The discussions largely echo the study's findings that microdosing LSD produces negligible effects, with words like 'lukewarm', 'no significant effects', and 'negligible changes' illustrating consensus. Several posts dismiss microdosing as ineffective, with some referencing multiple recent studies, which underscores a shared understanding that current evidence does not support the beneficial claims of microdosing.
AgreementStrong disagreement
All discussions uniformly emphasize that low-dose LSD has minimal or no observable benefits, strongly supporting the study's conclusion.
InterestNeutral interest
The discussions show moderate interest, mostly agreeing or dismissing the findings, with little exploration of potential broader implications.
EngagementLow engagement
Engagement appears superficial, often dismissing or summarizing without deep analysis, indicating low critical engagement.
ImpactLow impact
The collective tone underscores the limited impact of microdosing as per current evidence, reinforcing the idea that microdosing lacks significant benefits.
Abstract in brief
This study investigated the effects of repeated low doses of LSD (microdosing) taken every 3 to 4 days on healthy adults, comparing placebo and two microdose levels (13 or 26 micrograms) in a controlled setting.
The results showed that while a higher dose (26 micrograms) elicited some subjective effects like feeling the drug and stimulant-like sensations, it did not significantly improve mood or cognitive performance, and no lasting effects were observed.
The study concludes that microdosing LSD appears safe in a controlled environment but offers minimal benefits for mood or cognition based on the limited number of doses tested.]
Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think micro-dosing works are experiencing placebo effect.
It works because you think it does.
https://t.co/PAIcSZEZvr
Mar 26, 2022 · 29 likes · 5 shares · 79,376 followersView post →
OL
Olson Lab
@DEOlsonLab · X
nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers."
https://t.co/HosB8Y9J8K
Feb 14, 2022 · 29 likes · 8 shares · 2,762 followersView post →
ZT
Zeus Tipado
@tipado · X
New microdose study dropped a few days ago. They used doses slightly above traditional microdoses (13μg, 26μg) Result? No cognitive enhancement compared to placebo. Y’all gotta stop it with this microdosing smh https://t.co/jOr4TVoHL1
Feb 10, 2022 · 23 likes · 17,511 followersView post →
TM
Tyler Black, MD
@tylerblack32 · X
https://t.co/jR2b873kqA
A randomized, blinded study of LSD microdosing showed no differences in mood, affect performance, or cognition between microdosing & placebo.
Relatively on trend: Especially when blinding & expectancy controlled, small/insignificant psychedelics effect.
Jun 5, 2022 · 21 likes · 4 shares · 54,450 followersView post →
AP
Alaina Jaster, PhD
@JasterAlaina · X
Another paper that seemingly shows microdosing is not doing much of anything
https://t.co/et44HZ0SAA
Feb 3, 2022 · 18 likes · 4 shares · 2,815 followersView post →
B
BryanRoth
@zenbrainest · X
"We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers."
https://t.co/JQTuqEXTPX
Feb 2, 2022 · 13 likes · 5 shares · 17,144 followersView post →
This video introduces the use of pharmaceuticals and supplements for cognitive enhancement, discussing their impact on brain performance and decision-making. It explores how stimulants like methylphenidate, modafinil…
This episode examines the effects of microdosing LSD through a rigorous study. Repeated low doses were found to have minimal impact on mood or cognition in healthy adults, highlighting the need for scientific scrutiny…
Low dose LSD reduces the pain of social rejection
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study - PMC https://t.co/2pE5G6F7FK
3. This study showed that after giving repeated microdoses of LSD to healthy participants, without the participants knowing what they were taking (or even what the study was about), there was no improvement on mood or emotional tasks compared to placebo.
https://t.co/ufBfA6haxl
RT @psybalazs: Overall, I feel these results are similarly lukewarm as other trials in healthy samples (e.g. https://t.co/JtWDLpo7wa & http…
Mar 30, 2023 · 1 share · 20,781 followersView post →
BS
Balázs Szigeti
@psybalazs · X
Overall, I feel these results are similarly lukewarm as other trials in healthy samples (e.g. https://t.co/JtWDLpo7wa & https://t.co/tbwZ2LyAK5) - best case scenario is a small effect.
#microdose research needs to turn towards patient populations to see if there is more there.
Mar 29, 2023 · 13 likes · 1 share · 3,292 followersView post →
DB
DANIEL BRUMMITT
@dan__brummitt · X
RT @JanHaugland: Microdosing is BS. Techbros in tears. “We conclude that within the context of a controlled setting and a limited number of…
Oct 13, 2022 · 1 share · 28,565 followersView post →
HC
Hedgehog Psychotherapy & Counseling
@HedgeCounseling · X
Unfortunately their sample only include "healthy volunteers". I think the results would be different if participants studied had anxiety/ depression.
https://t.co/OwkQFk89oI
RT @tylerblack32: https://t.co/jR2b873kqA
A randomized, blinded study of LSD microdosing showed no differences in mood, affect performance…
Jun 5, 2022 · 4 shares · 3,344 followersView post →
JH
Jan Haugland
@JanHaugland · X
Microdosing is BS. Techbros in tears. “We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers.” https://t.co/iCOEJOWm7C
Jun 5, 2022 · 1 like · 1 share · 1,391 followersView post →
LR
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X
RT @tylerblack32: https://t.co/jR2b873kqA
A randomized, blinded study of LSD microdosing showed no differences in mood, affect performance…
Jun 5, 2022 · 4 shares · 10,467 followersView post →
MG
Molly Gordon
@shaboom · X
RT @tylerblack32: https://t.co/jR2b873kqA
A randomized, blinded study of LSD microdosing showed no differences in mood, affect performance…
Jun 5, 2022 · 4 shares · 12,872 followersView post →
SP
Stephen Pimentel
@StephenPiment · X
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study
https://t.co/atVsTg932C
Jun 5, 2022 · 2 likes · 12,793 followersView post →
TM
Tyler Black, MD
@tylerblack32 · X
https://t.co/jR2b873kqA
A randomized, blinded study of LSD microdosing showed no differences in mood, affect performance, or cognition between microdosing & placebo.
Relatively on trend: Especially when blinding & expectancy controlled, small/insignificant psychedelics effect.
Jun 5, 2022 · 21 likes · 4 shares · 54,450 followersView post →
MK
Mike Knickerbocker
@MJKnickerbocker · X
RT @jerryteixeira: Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think mic…
RT @jerryteixeira: Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think mic…
Mar 27, 2022 · 5 shares · 971 followersView post →
JB
Joshua Bell
@CoachCrazy · X
RT @jerryteixeira: Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think mic…
Mar 27, 2022 · 5 shares · 910 followersView post →
BM
Brett Muller
@BrettMuller5 · X
RT @jerryteixeira: Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think mic…
Mar 26, 2022 · 5 shares · 470 followersView post →
BT
Briana Theroux
@brianatheroux · X
RT @jerryteixeira: Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think mic…
Mar 26, 2022 · 5 shares · 2,409 followersView post →
JT
JT | Jerry Teixeira
@jerryteixeira · X
Micro-dosing LSD does not appear to improve cognitive performance vs placebo.
It may well be that people who think micro-dosing works are experiencing placebo effect.
It works because you think it does.
https://t.co/PAIcSZEZvr
Mar 26, 2022 · 29 likes · 5 shares · 79,376 followersView post →
DP
Dr K Wildschut OLD AGE Psychiatrist
@DrK_W1984 · X
@Herne_TheHunter @m_wall It is what it is I’m afraid- it’s the powerful placebo effect at work.
Many trials have concluded same
https://t.co/23feLUWgJh
Mar 24, 2022 · 1 like · 3,042 followersView post →
Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study - Wit - 2022 - Addiction Biology - Wiley Online Library
...the drug did not improve mood or affect performance on psychomotor or most emotional tasks.
https://t.co/vW9497zIHp
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study https://t.co/RL95arh3B1
"Repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers"
We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers.
https://t.co/0sdKAjoUL6
RT @BursatilBiotech: Surprise, surprise
"Repeated low doses of LSD in healthy adults:A placebo-controlled, dose–response study"
Result? L…
Feb 19, 2022 · 1 share · 1,354 followersView post →
BB
Bursatil Biotech
@BursatilBiotech · X
Surprise, surprise
"Repeated low doses of LSD in healthy adults:A placebo-controlled, dose–response study"
Result? LSD didnt improve mood or affect participants’ performance on cognitive tests, either during the drug sessions or at the follow-up session
https://t.co/4C4JZZ8EoA
Feb 19, 2022 · 3 likes · 1 share · 10,312 followersView post →
AA
Alex Andru
@phantomcolor · X
@tripapp @PaulAustin3w @RonanDLevy Are there any counter-references to this study that you can point me to?
https://t.co/heMPoWS9M7
RT @mankadmd: I really do want novel agents to work in psychiatry. But here’s another negative trial for LSD.
Feb 18, 2022 · 1 share · 7,417 followersView post →
MD
Mehul Mankad, M.D.
@mankadmd · X
I really do want novel agents to work in psychiatry. But here’s another negative trial for LSD.
Feb 18, 2022 · 4 likes · 1 share · 429 followersView post →
M
Maydrigo
@maydrigopsi · X
Saiu estudo duplo cego/placebo sobre uso de microdose de alucinógenos em adultos saudáveis que NÃO constatou efeitos positivos significantes no humor, cognição e emoções wm 4 sessões com 4 dias de intervalo. A amostra foi de 19 pessoas em cada grupo.
https://t.co/y5KOxjjFx3
Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study - Wit - 2022 - Addiction Biology - Wiley Online Library
Silicon Valley in shambles right now https://t.co/AgLoTSH7uc
1/ Researchers has found no evidence LSD microdosing improves mood or cognitive function. They conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are https://t.co/JFHVZnzEHB
Researchers has found no evidence LSD microdosing improves mood or cognitive function. They conclude that within the context of a controlled setting and a limited number of ad https://t.co/MTAzFyG39c https://t.co/JFuWpS0XBL
RT @NeuroscienceNew: “Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study” by Harriet de Wit et al. Addi…
Feb 17, 2022 · 4 shares · 888 followersView post →
E
Endquire
@Endquire · X
RT @NeuroscienceNew: “Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study” by Harriet de Wit et al. Addi…
Feb 17, 2022 · 4 shares · 401 followersView post →
DU
Diego Urgelés
@diegourgeles · X
Parece que, como ya se sabía desde los años 70, no funciona. https://t.co/CE6RpO0ipG
Feb 17, 2022 · 3 likes · 1 share · 340 followersView post →
J
jeffburdges
@jeffburdges · X
RT @NeuroscienceNew: “Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study” by Harriet de Wit et al. Addi…
Feb 17, 2022 · 4 shares · 1,711 followersView post →
BC
Big Island Reporter - TheBigIslandReporter.com
@BlueTurbanStone · X
RT @NeuroscienceNew: “Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study” by Harriet de Wit et al. Addi…
Feb 17, 2022 · 4 shares · 1,737 followersView post →
NN
Neuroscience News
@NeuroscienceNew · X
“Repeated low doses of LSD in healthy adults: A placebo‐controlled, dose–response study” by Harriet de Wit et al. Addiction Biology
https://t.co/NvLqT5To8J
Feb 17, 2022 · 9 likes · 4 shares · 506,832 followersView post →
A
Agingdoc
@agingdoc1 · X
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study
https://t.co/wbFwjWBS4L
Feb 17, 2022 · 6 likes · 43,201 followersView post →
AH
Andrew Yockey, PhD (He/Him)
@YockeyAndrew · X
“We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers.” https://t.co/n5aQqdzenM
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 15, 2022 · 8 shares · 200 followersView post →
DY
David B. Yaden
@ExistWell · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 7,198 followersView post →
DH
Dr Melissa Herman
@MelissaHerman4 · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 3,517 followersView post →
DM
Drug Monkey
@drugmonkeyblog · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 8,798 followersView post →
B
BryanRoth
@zenbrainest · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 17,144 followersView post →
K
KCt577
@Know__Cannabis · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 126 followersView post →
TH
Terry Hébert
@THebertMcGill · X
RT @DEOlsonLab: nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of adm…
Feb 14, 2022 · 8 shares · 2,189 followersView post →
OL
Olson Lab
@DEOlsonLab · X
nice paper from the de Wit group:
"We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers."
https://t.co/HosB8Y9J8K
Feb 14, 2022 · 29 likes · 8 shares · 2,762 followersView post →
LP
Lucas Maia, PhD
@lucasomaia · X
LSD microdoses showed no mood or cognition effects within the context of a controlled setting and a limited number (4 repeated doses) of administrations. Results from a recent randomized placebo-controlled study: https://t.co/06E88ttC1p
1/ A study found that "within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers." https://t.co/w7taLukUI6
New microdose study dropped a few days ago. They used doses slightly above traditional microdoses (13μg, 26μg) Result? No cognitive enhancement compared to placebo. Y’all gotta stop it with this microdosing smh https://t.co/jOr4TVoHL1
Feb 10, 2022 · 23 likes · 17,511 followersView post →
RL
Royce Lee
@royce_md · X
The de Wit lab shows that LSD microdoses show some signs of habituation in behavioral effects, no great change in mood, but do reduce rejection sensitivity in virtual game of cyberball: https://t.co/yqcRBFOXcC
Ytterligare en placebokontrollerad studie finner att mikrodosering av LSD har "negligerbara" effekter. Tror det har kommit tre sådana studier bara senaste året.
https://t.co/BlubEfhPL0
Börjar bli dags att lägga ner den hypen nu och satsa mer helhjärtat på makrodoser.
@NewEra_Picks @Psych_Fin @Harvard Funny you should say that, since almost every placebo-controlled study of microdosing has found it to be ineffective. For ex, this dropped today:
https://t.co/iqiZmp8duM
Feb 2, 2022 · 2 likes · 4,757 followersView post →
K
KCt577
@Know__Cannabis · X
RT @PsilocybinAlpha: More negative findings for microdosing?
"We conclude that within the context of a controlled setting and a limited nu…
RT @zenbrainest: "We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses o…
Feb 2, 2022 · 5 shares · 2,069 followersView post →
B
BryanRoth
@zenbrainest · X
"We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers."
https://t.co/JQTuqEXTPX
Feb 2, 2022 · 13 likes · 5 shares · 17,144 followersView post →
TL
Tammy Le
@tams888 · X
RT @theradelics: Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study https://t.co/zMegr18oGE https://t.c…
More negative findings for microdosing?
"We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are safe, but produce negligible changes in mood or cognition in healthy volunteers."
https://t.co/4bFXyHfyqA
Feb 2, 2022 · 5 likes · 1 share · 20,781 followersView post →
T
THERADELICS
@theradelics · X
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study https://t.co/Zhx2YFeOnn https://t.co/kN4YdHRsqa
Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study https://t.co/zMegr18oGE https://t.co/6Mn8Eh6Lu3
Feb 2, 2022 · 1 like · 1 share · 3,393 followersView post →
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