Nat Prod Bioprospect February 2022 PMID 35157175

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2.

Wenting Liu, Weikang Zheng, Liping Cheng, Ming Li, Jie Huang, Shuzheng Bao, Qiang Xu, Zhaocheng Ma

Mentions

21
Peak: 9 in Feb 2023
across 4 sources since Apr 2022

Extended reach

29,793
potential audience

Total likes

18

Video views

101

Mentions per month

Apr 2022 – Dec 2025

Where it's discussed

  • X / Twitter15 posts
  • Facebook3 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

The group demonstrates strong agreement by emphasizing the potential of citrus flavonoids in blocking virus entry, as seen in statements about ACE2 receptors and health benefits, while interest is driven by personal and practical implications, such as claims that citrus saved lives. The tone reflects a mix of scientific enthusiasm and personal anecdotal reassurance, indicating recognition of the research's importance without extensive critical analysis.

AgreementStrong agreement

Most discussions reinforce the idea that citrus fruits contain beneficial flavonoids targeting ACE2, supporting the article’s claims.

InterestModerate interest

Participants show moderate curiosity, especially those mentioning personal health benefits and the relevance of citrus in preventing viral entry.

EngagementModerate engagement

Posts reflect some engagement through referencing biological mechanisms and personal anecdotes, but mostly remain surface-level.

ImpactHigh impact

Given the focus on health benefits and potential preventative strategies, the discussions highlight significant perceived impact of the research findings.

Abstract in brief

  • This text discusses the potential of citrus fruits, especially their flavonoids, in fighting COVID-19 by enhancing immunity and inhibiting the virus, with specific focus on compounds like hesperetin, naringin, and naringenin.
  • Studies showed that naringin could suppress inflammatory cytokines and may help prevent cytokine storms associated with severe COVID-19 cases, suggesting a possible therapeutic role.
  • Molecular docking simulations indicate that citrus flavonoids may bind to ACE2 receptors, the entry points for the coronavirus, highlighting their potential as preventive or treatment agents against SARS-CoV-2.]

Top posts

Most liked on X and Bluesky
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

@GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are attacking the body, the same treatment for scurvy amazing.

Feb 14, 2023 · 9 likes · 4 shares · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 - PubMed look at this every lemons on this virus or its entry point into your DNA. It stops it that’s what saved my life and others. https://t.co/FXPdwDhbOE

Feb 14, 2023 · 1 like · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

https://t.co/FXPdwDhbOE

Feb 14, 2023 · 1 like · 1 share · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 - PMC https://t.co/FZgER8Fp9t

Dec 2, 2023 · 1 like · 2,304 followers View post →
Korey
@korey72758 · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 15, 2023 · 4 shares · 7,343 followers View post →
KeepItReal
@kateebvintage · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 17, 2023 · 4 shares · 3,232 followers View post →

All mentions

Gerard Hough
@GerardHough · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 https://t.co/1zBtshbJtq

Oct 15, 2024 · 1,754 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 - PMC https://t.co/FZgER8Fp9t

Dec 2, 2023 · 1 like · 2,304 followers View post →
Truth Over Tyranny
@RacquelforTruth · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 17, 2023 · 4 shares · 2,772 followers View post →
KeepItReal
@kateebvintage · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 17, 2023 · 4 shares · 3,232 followers View post →
Korey
@korey72758 · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 15, 2023 · 4 shares · 7,343 followers View post →
Stell
@osmak_estelle · X

RT @Trueknight77777: @GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are a…

Feb 14, 2023 · 4 shares · 17 followers View post →
Hoofsrulestheroost
@Hoofsrulesther1 · X

RT @Trueknight77777: https://t.co/FXPdwDhbOE

Feb 14, 2023 · 1 share · 1,338 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

@GlobalFreedomM https://t.co/FXPdwDhbOE that’s why this works on the virus. It works on ACE2 receptor where they are attacking the body, the same treatment for scurvy amazing.

Feb 14, 2023 · 9 likes · 4 shares · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

@DocPeteChambers That’s why citrus acid works. It works on the AC2 receptors that are being affected by the virus. https://t.co/FXPdwDhbOE

Feb 14, 2023 · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

https://t.co/FXPdwDhbOE

Feb 14, 2023 · 1 like · 1 share · 2,304 followers View post →
Call Me TOTO….The Natural Born Medicain Man….
@Trueknight77777 · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 - PubMed look at this every lemons on this virus or its entry point into your DNA. It stops it that’s what saved my life and others. https://t.co/FXPdwDhbOE

Feb 14, 2023 · 1 like · 2,304 followers View post →
Megan Elizabeth Graham
@grahamemegan · X

(PDF) Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 https://t.co/XjwNlYlDWB

Jan 7, 2023 · 299 followers View post →
Megan Elizabeth Graham
@grahamemegan · X

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2 https://t.co/IlRrZkLv2X

Dec 30, 2022 · 299 followers View post →
文月宵(ケトン人)
@fumizukishou_bc · X

“柑橘系の果物は、免疫調節とACE2を標的とする可能性のあるフラボノイドが豊富です” 柑橘類のフラボノイドがACE2からの侵入を競合的にブロックするだろうという研究 ナリンギン、ヘスペリジンあたりが強力 こたつみかんと緑茶は日本の冬の守り神やっていう https://t.co/elERyr9JUQ

May 4, 2022 · 736 followers View post →
Megan Elizabeth Graham
@grahamemegan · X

Citrus Fruits Are Rich in Flavonoids for Immunoregulation and Potential Targeting ACE2[v1] | Preprints https://t.co/wrQiW1TyTQ

Apr 30, 2022 · 299 followers View post →
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doi: 10.1007/s13659-022-00325-4. PMID: 35157175; PMCID: PMC8844329. Barghouthy Y, Somani BK. Role of Citrus Fruit Juices in Prevention of Kidney Stone ...

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... 10.1007/s13659-022-00325-4. PMID: 35157175; PMCID: PMC8844329. Barghouthy Y, Somani BK. Role of Citrus Fruit Juices in Prevention of Kidney ...

Dec 8, 2025 View →
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DOI: https://doi.org/10.1007/s13659-022-00325-4. DOI: https://doi.org/10.31989/ffs.v2i3.906. 46. Wang Y, Mou Y, Lu S, Xia Y, Cheng B ...

Feb 20, 2025 View →
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doi: 10.1007/s13659-022-00325-4. PMID: 35157175; PMCID: PMC8844329. Barghouthy Y, Somani BK. Role of Citrus Fruit Juices in Prevention of ...

Jan 23, 2025 View →