Int J Cancer July 2022 PMID 35213038

Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage.

Samuel T Orange, Alastair R Jordan, Adam Odell, Owen Kavanagh, Kirsty M Hicks, Tristan Eaglen, Stephen Todryk, John M Saxton

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Mentions

143
Peak: 41 in Apr 2022
across 4 sources since Mar 2022

Extended reach

224,032
potential audience

Total likes

156

Video views

272

Mentions per month

Mar 2022 – Jan 2023

Where it's discussed

  • News71 articles
  • X / Twitter68 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Several discussions highlight the study's findings, such as posts that mention how post-exercise serum can reduce colon cancer cell growth and DNA damage. Phrases like 'potential mechanism' and 'decrease the risk for cancer' help convey the transformative nature of these findings, and the overall tone reflects enthusiasm and urgency regarding the implications of this research.

AgreementStrong agreement

Many discussions express strong support for the findings, highlighting a consensus on the benefits of exercise in relation to cancer prevention.

InterestHigh interest

There is a high level of curiosity, with numerous posts referencing the specifics of the research, showing that audiences are engaged with the topic.

EngagementModerate engagement

While several posts reference the research, not all delve into methods or broader implications, indicating a moderate level of engagement.

ImpactHigh impact

Users generally perceive the research as offering significant insights into cancer prevention strategies linked to physical activity.

Abstract in brief

  • Regular physical activity may lower the risk of colon cancer, but the specific mechanisms behind this effect are not well understood.
  • In a study, human colon cancer cells (LoVo) were exposed to serum collected from participants before and after moderate-intensity aerobic exercise, revealing that post-exercise serum significantly reduced cancer cell growth and DNA damage.
  • The reduction in cancer cell proliferation was linked to increased levels of interleukin-6 (IL-6) in the serum, suggesting that IL-6 may play a crucial role in how acute exercise impacts colon cancer biology.

Top posts

Most liked on X and Bluesky
Dr Alexey Kulikov
@KulikovUNIATF · X

Exercise ⛹

Apr 9, 2022 · 57 likes · 31 shares · 62,991 followers View post →
Sam Orange
@SamOrange01 · X

New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage" https://t.co/CKRcFCSZuB Brief thread https://t.co/RVx5nvjEHY

Mar 16, 2022 · 41 likes · 9 shares · 1,166 followers View post →
Scott Lear, PhD
@DrScottLear · X

#MondayMotivation to keep active: Regular activity is associated with ⬇️ colorectal #cancer. This study indicates blood taken after a 30-min bout of #exercise can result in decreased cancer cell reproduction and DNA damage: https://t.co/JwBiNBHrgz https://t.co/e1jnzlDPpE

Apr 11, 2022 · 7 likes · 3 shares · 3,033 followers View post →
International Journal of Cancer
@IntJCanc · X

NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is mediated by decreased #DNAdamage and increase in serum #IL6

Mar 24, 2022 · 7 likes · 4 shares · 1,788 followers View post →
Kirsty Hicks
@KirstyHicks88 · X

Enjoyed working on our paper published in @IntJCanc

Mar 17, 2022 · 7 likes · 3 shares · 1,221 followers View post →
Newcastle Biomedical, Nutrition & Sport Sci
@NclBNS · X

Dr @SamOrange01 for his paper investigating the effects of aerobic exercise-conditioned serum on colon cancer cell proliferation: https://t.co/GHW7etxKjh https://t.co/qIwjbrywse

Mar 18, 2022 · 4 likes · 2 shares · 1,856 followers View post →

All mentions

Human Nutrition & Exercise Research Centre
@HNERC_NclUni · X

Sam’s laboratory-based research has revealed a potential biological mechanism explaining how physical activity slows the progression of colon cancer. https://t.co/j6hNmx2YlT https://t.co/fL8csuXmIr

Jan 30, 2023 · 1 like · 1,215 followers View post →
Dr Rachel Stocker
@RachelStocker · X

RT @SamOrange01: Nice blog that aligns well with our recent findings: Acute aerobic exercise-conditioned serum reduces colon cancer cell p…

Oct 21, 2022 · 1 share · 1,024 followers View post →
Sam Orange
@SamOrange01 · X

Nice blog that aligns well with our recent findings: Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage https://t.co/CKRcFCTxk9 https://t.co/fvdNL3fAg4

Oct 21, 2022 · 2 likes · 1 share · 1,166 followers View post →
Jasem Alqallaf
@jq_nutrition · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Aug 17, 2022 · 9 shares · 818 followers View post →
Sam Orange
@SamOrange01 · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Aug 17, 2022 · 9 shares · 1,166 followers View post →
International Journal of Cancer
@IntJCanc · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Aug 17, 2022 · 9 shares · 1,788 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Acute aerobic exercise‐conditioned serum reduces c…" (https://t.co/tvWWm4NzRJ) included RRIDs in their paper! We appreciate the author's support of reproducibility. #reproducibility #STMpublishing

Aug 5, 2022 · 161 followers View post →
International Journal of Cancer
@IntJCanc · X

RT @SamOrange01: There was a letter to the editor on our paper published in @IntJCanc Original (open access) https://t.co/CKRcFCSZuB Lett…

Jun 23, 2022 · 1 share · 1,788 followers View post →
Sam Orange
@SamOrange01 · X

There was a letter to the editor on our paper published in @IntJCanc Original (open access) https://t.co/CKRcFCSZuB Letter by Jiang & Yang https://t.co/pDfx86T0OU Our response https://t.co/k0cHtrn8Df https://t.co/HfvAJ6Yjsx

Jun 22, 2022 · 1 like · 1 share · 1,166 followers View post →
kuri14
@kuri14mr · X

運動を長期間に、毎週、複数回繰り返す。 すると、血流にガンと戦う物質が放出されます! そして、それらがDNAを修復して、加えて細胞が癌化するのを抑える可能性があるそうですよ! 運動素晴らしい!みんな、運動だ!! #運動 #長期的 #ガン予防 https://t.co/FmHSXJXURG

Apr 16, 2022 · 2 likes · 33 followers View post →
Lisal Folsom
@DocFolsom · X

What if moving your body could decrease the risk for cancer? #exercise #activity #move #cancerrisk #beatcancer https://t.co/ErrMZXvqO1

Apr 15, 2022 · 1 like · 425 followers View post →
Solimut Mutuelle
@SolimutMutuelle · X

#ETUDESANTEDUSOIR Parce qu'il libère des protéines anticancéreuses dans le sang (interleukine-6), le #sport aide à réparer les cellules potentiellement endommagées et réduit le risque de développer un #cancer (ex. avec cancer colorectal) Via @IntJCanc https://t.co/M0rb7FyRq7

Apr 13, 2022 · 2,654 followers View post →
Prof. Biology
@ResearchBiology · X

International Journal of Cancer- Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage. https://t.co/rt5CCfvutJ

Apr 11, 2022 · 601 followers View post →
Marina Mourtzakis, PhD
@MourtzakisM · X

RT @DrScottLear: #MondayMotivation to keep active: Regular activity is associated with ⬇️ colorectal #cancer. This study indicates blood…

Apr 11, 2022 · 3 shares · 242 followers View post →
Scott Lear, PhD
@DrScottLear · X

#MondayMotivation to keep active: Regular activity is associated with ⬇️ colorectal #cancer. This study indicates blood taken after a 30-min bout of #exercise can result in decreased cancer cell reproduction and DNA damage: https://t.co/JwBiNBHrgz https://t.co/e1jnzlDPpE

Apr 11, 2022 · 7 likes · 3 shares · 3,033 followers View post →
Dr Carol Granger
@CarolGranger2 · X

Exercise shown to release protein reducing bowel cancer risk. https://t.co/RdJ7RINXwO

Apr 11, 2022 · 1 like · 358 followers View post →
Ghazi/غازي
@Gfphar1214 · X

https://t.co/xuQVr3GrfK

Apr 10, 2022 · 2 likes · 1,322 followers View post →
Latif Patel
@LatifPatel14 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 10, 2022 · 31 shares · 2,061 followers View post →
Dr. د. عبدالواحد الزهراني
@ralzahrani2020 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 10, 2022 · 31 shares · 4,366 followers View post →
Bongani Mayosi Health Sciences Library (BMHSL)
@uct_bmhsl · X

RT @KulikovUNIATF: Exercise ⛹

Apr 10, 2022 · 31 shares · 1,598 followers View post →
Maya Romani
@MayaRomani · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 945 followers View post →
ann mcsorley
@annimac57 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 159 followers View post →
Dr Patricia Rarau
@rarau_p · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 223 followers View post →
Clare Drummy
@ClareDrummy · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 245 followers View post →
KathMorrow90
@KathMorrow90 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 2,334 followers View post →
Dr Wondi Alemu
@alemuw1 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 22,120 followers View post →
Gabriela Llerena P.
@nutgllerena · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 885 followers View post →
Physio_ Leanne SIMONCELLI
@PhysioSIMONCEL1 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 376 followers View post →
Michele Verroken
@SportIntegrity · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 2,313 followers View post →
Jeroen Swart
@JeroenSwart · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 11,482 followers View post →
Etain Kett MPRII
@EtainKett1 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 567 followers View post →
Yun-ting Lin
@yunting____ · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 31 followers View post →
Lynder
@lynderlinda · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 1,838 followers View post →
daniel varela PhD
@dr_dvarela_P4T · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 919 followers View post →
Ganjasmoker
@GanjasmokerCb · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 2,330 followers View post →
Bruno Moura, PhD
@moura_bp · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 458 followers View post →
Agnes Ayton
@AgnesAyton · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 7,396 followers View post →
Tyra Ann
@Tyra_Ann7 · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 460 followers View post →
AOLMahuaDS
@AOLMahuaDS · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 3,552 followers View post →
syawal™ シ
@syawal · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 3,183 followers View post →
Ifeanyi Nsofor
@ekemma · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 21,119 followers View post →
Taro Shiga, MD, PhD
@OncoCard_Ganken · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 1,033 followers View post →
Active Life Club
@ActiveLifeClub · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 540 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

RT @KulikovUNIATF: Exercise ⛹

Apr 9, 2022 · 31 shares · 4,574 followers View post →
Dr Alexey Kulikov
@KulikovUNIATF · X

Exercise ⛹

Apr 9, 2022 · 57 likes · 31 shares · 62,991 followers View post →
Ala_Haddadin,MD,MHA
@ashaddadin11 · X

https://t.co/5CQMXMZZsq

Apr 8, 2022 · 438 followers View post →
Ariakas Enoreth
@Aenoreth · X

Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage https://t.co/0r4f31jtYt

Apr 8, 2022 · 1,004 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage - International Journal of Cancer Interesting & provocative as IL6 can promote cancer and is a therapy target https://t.co/cXrAF98clI

Apr 7, 2022 · 18,512 followers View post →
Dr Anthony Martin
@AMAinsight · X

Acute aerobic exercise‐conditioned serum reduces colon cancer cell proliferation in vitro through interleukin‐6‐induced regulation of DNA damage - Orange - - International Journal of Cancer - Wiley Online Library https://t.co/KAv1Chl7lZ

Apr 7, 2022 · 1 like · 1 share · 913 followers View post →
Yannick Romero, PhD
@YannickRomero · X

RT @IntJCanc: NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is media…

Mar 24, 2022 · 4 shares · 657 followers View post →
Dr. Henrique Mansur
@HenriqueMansur7 · X

RT @IntJCanc: NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is media…

Mar 24, 2022 · 4 shares · 31 followers View post →
John Saxton
@JohnSaxton19 · X

RT @IntJCanc: NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is media…

Mar 24, 2022 · 4 shares · 464 followers View post →
Sam Orange
@SamOrange01 · X

RT @IntJCanc: NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is media…

Mar 24, 2022 · 4 shares · 1,166 followers View post →
International Journal of Cancer
@IntJCanc · X

NOW ONLINE study by @samorange01 @Uni_Newcastle #PhysicalActivity reduces #cellproliferation in colon - The effect is mediated by decreased #DNAdamage and increase in serum #IL6

Mar 24, 2022 · 7 likes · 4 shares · 1,788 followers View post →
Chris Hurst
@chrishurst99 · X

RT @NclBNS: Dr @SamOrange01 for his paper investigating the effects of aerobic exercise-conditioned serum on colon cancer cell proliferatio…

Mar 18, 2022 · 2 shares · 1,060 followers View post →
Sam Orange
@SamOrange01 · X

RT @NclBNS: Dr @SamOrange01 for his paper investigating the effects of aerobic exercise-conditioned serum on colon cancer cell proliferatio…

Mar 18, 2022 · 2 shares · 1,166 followers View post →
Newcastle Biomedical, Nutrition & Sport Sci
@NclBNS · X

Dr @SamOrange01 for his paper investigating the effects of aerobic exercise-conditioned serum on colon cancer cell proliferation: https://t.co/GHW7etxKjh https://t.co/qIwjbrywse

Mar 18, 2022 · 4 likes · 2 shares · 1,856 followers View post →
土橋祥平 Shohei Dobashi
@shoheidobashi · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Mar 17, 2022 · 9 shares · 796 followers View post →
Georgina Stebbings
@stebbina · X

RT @KirstyHicks88: Enjoyed working on our paper published in @IntJCanc

Mar 17, 2022 · 3 shares · 838 followers View post →
Sam Orange
@SamOrange01 · X

RT @KirstyHicks88: Enjoyed working on our paper published in @IntJCanc

Mar 17, 2022 · 3 shares · 1,166 followers View post →
Jade B
@JAD3_B · X

RT @KirstyHicks88: Enjoyed working on our paper published in @IntJCanc

Mar 17, 2022 · 3 shares · 252 followers View post →
Kirsty Hicks
@KirstyHicks88 · X

Enjoyed working on our paper published in @IntJCanc

Mar 17, 2022 · 7 likes · 3 shares · 1,221 followers View post →
MartinBondSWFC
@MartinBondSWFC · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Mar 16, 2022 · 9 shares · 315 followers View post →
Rebecca Robinson
@rjprobinson · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Mar 16, 2022 · 9 shares · 3,466 followers View post →
Jordan Curry, PhD
@JordanCurry2 · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Mar 16, 2022 · 9 shares · 1,123 followers View post →
Newcastle Biomedical, Nutrition & Sport Sci
@NclBNS · X

RT @SamOrange01: New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-condi…

Mar 16, 2022 · 9 shares · 1,856 followers View post →
Sam Orange
@SamOrange01 · X

New paper in @IntJCanc identifying a potential mechanism of exercise and cancer prevention. "Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage" https://t.co/CKRcFCSZuB Brief thread https://t.co/RVx5nvjEHY

Mar 16, 2022 · 41 likes · 9 shares · 1,166 followers View post →
Tom
@howtobeatcancer · X

Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation through IL-6-induced regulation of DNA damage in vitro https://t.co/gJ4vfnI6oQ

Mar 1, 2022 · 1,453 followers View post →