Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial.
Overall, the discussions express strong agreement, with commenters calling the trial results a 'gamechanger' and noting that Y90 outperforms traditional methods, supported by remarks about the level I evidence from the trial. Their tone and focus on clinical implications demonstrate deep engagement and highlight the potential impact on treatment strategies for unresectable hepatocellular carcinoma.
AgreementStrong agreement
Most discussions highlight support for the study's positive findings favoring Yttrium-90 radioembolization, reflecting strong agreement with the research conclusions.
InterestHigh interest
The discussions demonstrate high interest by emphasizing the significance of the trial's results and calling it a 'gamechanger,' indicating active engagement with the topic.
EngagementHigh engagement
Participants reference specific trial outcomes, such as improved overall survival and time to tumor progression, showing deep engagement and analysis of the research findings.
ImpactHigh impact
The widespread sharing of the study among prominent radiology and oncology communities suggests a significant influence on current treatment approaches and clinical practice discussions.
Abstract in brief
Transarterial chemoembolization (TACE) is the standard treatment for intermediate hepatocellular carcinoma (HCC), but a study compared it to yttrium 90 (Y) transarterial radioembolization (TARE) as a potential alternative.
In a trial involving participants with intermediate-stage HCC, TARE showed a significantly longer median time to tumor progression (17.1 months) and overall survival (30.2 months) compared to DEB-TACE (9.5 months and 15.6 months, respectively).
Both treatments had similar rates of serious adverse events and mortality, leading researchers to conclude that TARE is a promising option with comparable safety to TACE for
@rlevitinMD @nbn426 I think that’s the real question at present.
There are data from a prospective phase 2 RCT supporting improved OS with TARE compared with DEB-TACE. Pts were predominately BCLC-B
https://t.co/IqNd7mmDxN
Oct 21, 2023 · 2 likes · 1 share · 3,853 followersView post →
JD
Jeroen Dekervel
@JDekervel · X
@jryckman3 https://t.co/FfywQ96lTy
Jan 3, 2024 · 2 likes · 1 share · 678 followersView post →
This video summarizes research comparing yttrium-90 radioembolization to drug-eluting bead chemoembolization for unresectable hepatocellular carcinoma, highlighting improved tumor control and survival outcomes with Y-90…
This episode discusses the latest clinical data on combining transarterial chemoembolization and immunotherapy for hepatocellular carcinoma. The doctors explore emerging treatment trends, multidisciplinary approaches…
@rlevitinMD @nbn426 I think that’s the real question at present.
There are data from a prospective phase 2 RCT supporting improved OS with TARE compared with DEB-TACE. Pts were predominately BCLC-B
https://t.co/IqNd7mmDxN
Oct 21, 2023 · 2 likes · 1 share · 3,853 followersView post →
MH
Melissa Hogg
@HoggNDMD · X
RT @MarcDiMartino:
Jun 10, 2023 · 3 shares · 2,401 followersView post →
NR
Niki Rashidian
@Niki_Rashidian · X
RT @MarcDiMartino:
Jun 10, 2023 · 3 shares · 236 followersView post →
AR
Alejandro Rosales
@HpbNicaragua · X
RT @MarcDiMartino:
Jun 9, 2023 · 3 shares · 1,337 followersView post →
MM
Marcello Di Martino
@MarcDiMartino · X
Jun 9, 2023 · 11 likes · 3 shares · 1,696 followersView post →
BT
Brad Trent
@tbtrentMD · X
@liverwei @navale_pooja @DrGeeONE @ariella8 @vij_mukul @LiverPath_HPHS @liverpath @UKLiverPath Thanks for sending me down the rabbit hole
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
May 6, 2022 · 24 shares · 4,242 followersView post →
HV
Hans Van Vlierberghe
@HansVlierberghe · X
<sup>90</sup>Y Proud about this gamechanger!! Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial https://t.co/HSUQdkdPki
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 26, 2022 · 24 shares · 396 followersView post →
JS
Jamil Shaikh
@JShaikhVIR · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 25, 2022 · 21 shares · 269 followersView post →
SP
Salvador Pedraza
@salvasapedraza · X
90Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial | Radiology https://t.co/SFy7ZhMGkG https://t.co/XF0BW2Dr4h
Mar 19, 2022 · 1 like · 6,525 followersView post →
MT
Muhammad Mohid Tahir
@MuhammadMohidT · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 13, 2022 · 21 shares · 112 followersView post →
MD
Mike Devane
@amdevane · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 11, 2022 · 24 shares · 1,812 followersView post →
TW
Thomas Wong
@TWongMD · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 11, 2022 · 24 shares · 281 followersView post →
MM
Manish Dhyani, MD
@M_Dhyani · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 10, 2022 · 24 shares · 618 followersView post →
BR
Brian S. Wong, MD, MPH, RPVI
@brianswongmd · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 10, 2022 · 21 shares · 332 followersView post →
HY
Heera Yoen
@Heera_Yoen · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 10, 2022 · 24 shares · 111 followersView post →
JH
Julia Hileman
@Jkhileman · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 10, 2022 · 21 shares · 181 followersView post →
VF
Vance Forte
@vrforte · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 10, 2022 · 24 shares · 447 followersView post →
NK
Nevin de Korompay
@NevdeK · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 10, 2022 · 24 shares · 783 followersView post →
DS
Debkumar Sarkar
@debkumarsarkar · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 764 followersView post →
JF
Julie Fung
@fung_julie · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 283 followersView post →
C
Cain
@IR_Cain · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 368 followersView post →
NK
Nevin de Korompay
@NevdeK · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 783 followersView post →
A
AileenOShea
@AileenO_Shea · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 300 followersView post →
TR
The Arab Journal of Interventional Radiology
@Arabjir · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 1,522 followersView post →
KE
Kareem Elfatairy
@kareemfatairy · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 385 followersView post →
KD
Kelly N Davis, DO
@kellyndavis · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 21 shares · 157 followersView post →
Hا
Hassan ALQarni, MD حسن القرني
@Qarnihassan4 · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 924 followersView post →
RS
Rene Sarria
@ReneSarria · X
RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…
Mar 9, 2022 · 74 likes · 21 shares · 3,757 followersView post →
LT
Linda Tutty
@LindaTutty · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 730 followersView post →
CM
Cynthia De la Garza, MD
@cyndlg · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 1,857 followersView post →
AM
Alex J. Solomon, MD
@alexjsolomonIR · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 316 followersView post →
FM
Francis Deng, MD
@francisdeng · X
RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…
Mar 9, 2022 · 24 shares · 16,963 followersView post →
RM
Ryan England, MD
@RyanWEngland · X
Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phase 2 randomized controlled trial.
#InAMinute @RadiologyEditor #RadInTraining @RadITrainEditor @radiology_rsna
Mar 9, 2022 · 67 likes · 24 shares · 1,044 followersView post →
PO
Paperbirds_Oncology
@PaperbirdsO · X
New article: 90Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial https://t.co/I2b10sS9cS #livercancer #oncology https://t.co/7lR2v0UY8q