Radiology June 2022 PMID 35258371

Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial.

Elisabeth Dhondt, Bieke Lambert, Laurens Hermie, Lynn Huyck, Peter Vanlangenhove, Anja Geerts, Xavier Verhelst, Maridi Aerts, Aude Vanlander, Frederik Berrevoet, Roberto Ivan Troisi, Hans Van Vlierberghe, Luc Defreyne

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Mentions

60
Peak: 43 in Mar 2022
across 3 sources since Mar 2022

Extended reach

86,034
potential audience

Total likes

171

Video views

612

Mentions per month

Mar 2022 – Apr 2025

Where it's discussed

  • X / Twitter55 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Overall, the discussions express strong agreement, with commenters calling the trial results a 'gamechanger' and noting that Y90 outperforms traditional methods, supported by remarks about the level I evidence from the trial. Their tone and focus on clinical implications demonstrate deep engagement and highlight the potential impact on treatment strategies for unresectable hepatocellular carcinoma.

AgreementStrong agreement

Most discussions highlight support for the study's positive findings favoring Yttrium-90 radioembolization, reflecting strong agreement with the research conclusions.

InterestHigh interest

The discussions demonstrate high interest by emphasizing the significance of the trial's results and calling it a 'gamechanger,' indicating active engagement with the topic.

EngagementHigh engagement

Participants reference specific trial outcomes, such as improved overall survival and time to tumor progression, showing deep engagement and analysis of the research findings.

ImpactHigh impact

The widespread sharing of the study among prominent radiology and oncology communities suggests a significant influence on current treatment approaches and clinical practice discussions.

Abstract in brief

  • Transarterial chemoembolization (TACE) is the standard treatment for intermediate hepatocellular carcinoma (HCC), but a study compared it to yttrium 90 (Y) transarterial radioembolization (TARE) as a potential alternative.
  • In a trial involving participants with intermediate-stage HCC, TARE showed a significantly longer median time to tumor progression (17.1 months) and overall survival (30.2 months) compared to DEB-TACE (9.5 months and 15.6 months, respectively).
  • Both treatments had similar rates of serious adverse events and mortality, leading researchers to conclude that TARE is a promising option with comparable safety to TACE for

Top posts

Most liked on X and Bluesky
NorthwesternIR
@NorthwesternIR · X

TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesociety @AASLDtweets @EASLnews @SIRspecialists @ASTRO_org @radiology_rsna @JVIRmedia @bsc_io @SirtexMedical @RSNA https://t.co/kNiVrTpmXl

Mar 9, 2022 · 74 likes · 21 shares · 3,757 followers View post →
Ryan England, MD
@RyanWEngland · X

Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phase 2 randomized controlled trial. #InAMinute @RadiologyEditor #RadInTraining @RadITrainEditor @radiology_rsna

Mar 9, 2022 · 67 likes · 24 shares · 1,044 followers View post →
Marcello Di Martino
@MarcDiMartino · X

Jun 9, 2023 · 11 likes · 3 shares · 1,696 followers View post →
Jeroen Dekervel
@JDekervel · X

@SprakerMDPhD @NiuSanford Not much but there is a small RCT showing OS benefit vs TACE in intermediate stage HCC https://t.co/DBOGXjscKt

Feb 26, 2025 · 3 likes · 678 followers View post →
Krishan Jethwa
@KrishanJethwa · X

@rlevitinMD @nbn426 I think that’s the real question at present. There are data from a prospective phase 2 RCT supporting improved OS with TARE compared with DEB-TACE. Pts were predominately BCLC-B https://t.co/IqNd7mmDxN

Oct 21, 2023 · 2 likes · 1 share · 3,853 followers View post →
Jeroen Dekervel
@JDekervel · X

@jryckman3 https://t.co/FfywQ96lTy

Jan 3, 2024 · 2 likes · 1 share · 678 followers View post →

All mentions

Jeroen Dekervel
@JDekervel · X

@SprakerMDPhD @NiuSanford Not much but there is a small RCT showing OS benefit vs TACE in intermediate stage HCC https://t.co/DBOGXjscKt

Feb 26, 2025 · 3 likes · 678 followers View post →
Jeff Ryckman
@jryckman3 · X

RT @JDekervel: @jryckman3 https://t.co/FfywQ96lTy

Jan 3, 2024 · 1 share · 4,636 followers View post →
Jeroen Dekervel
@JDekervel · X

@jryckman3 https://t.co/FfywQ96lTy

Jan 3, 2024 · 2 likes · 1 share · 678 followers View post →
R. Waterschoot
@rob_nucMD · X

@jryckman3 Yes, here's another trial supporting this: https://t.co/k86tIed3g0

Jan 3, 2024 · 1 like · 4 followers View post →
Amit Chowdhry, MD, PhD
@amit_chowdhry · X

RT @KrishanJethwa: @rlevitinMD @nbn426 I think that’s the real question at present. There are data from a prospective phase 2 RCT support…

Oct 21, 2023 · 1 share · 700 followers View post →
Krishan Jethwa
@KrishanJethwa · X

@rlevitinMD @nbn426 I think that’s the real question at present. There are data from a prospective phase 2 RCT supporting improved OS with TARE compared with DEB-TACE. Pts were predominately BCLC-B https://t.co/IqNd7mmDxN

Oct 21, 2023 · 2 likes · 1 share · 3,853 followers View post →
Melissa Hogg
@HoggNDMD · X

RT @MarcDiMartino:

Jun 10, 2023 · 3 shares · 2,401 followers View post →
Niki Rashidian
@Niki_Rashidian · X

RT @MarcDiMartino:

Jun 10, 2023 · 3 shares · 236 followers View post →
Alejandro Rosales
@HpbNicaragua · X

RT @MarcDiMartino:

Jun 9, 2023 · 3 shares · 1,337 followers View post →
Marcello Di Martino
@MarcDiMartino · X

Jun 9, 2023 · 11 likes · 3 shares · 1,696 followers View post →
Brad Trent
@tbtrentMD · X

@liverwei @navale_pooja @DrGeeONE @ariella8 @vij_mukul @LiverPath_HPHS @liverpath @UKLiverPath Thanks for sending me down the rabbit hole

Jun 8, 2022 · 2,030 followers View post →
ALEKENT
@Alekent · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

May 6, 2022 · 24 shares · 4,242 followers View post →
Hans Van Vlierberghe
@HansVlierberghe · X

<sup>90</sup>Y Proud about this gamechanger!! Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial https://t.co/HSUQdkdPki

Apr 9, 2022 · 1 like · 298 followers View post →
Eric Bready
@eruckinator · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 26, 2022 · 24 shares · 396 followers View post →
Jamil Shaikh
@JShaikhVIR · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 25, 2022 · 21 shares · 269 followers View post →
Salvador Pedraza
@salvasapedraza · X

90Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial | Radiology https://t.co/SFy7ZhMGkG https://t.co/XF0BW2Dr4h

Mar 19, 2022 · 1 like · 6,525 followers View post →
Muhammad Mohid Tahir
@MuhammadMohidT · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 13, 2022 · 21 shares · 112 followers View post →
Mike Devane
@amdevane · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 11, 2022 · 24 shares · 1,812 followers View post →
Thomas Wong
@TWongMD · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 11, 2022 · 24 shares · 281 followers View post →
Manish Dhyani, MD
@M_Dhyani · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 10, 2022 · 24 shares · 618 followers View post →
Brian S. Wong, MD, MPH, RPVI
@brianswongmd · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 10, 2022 · 21 shares · 332 followers View post →
Heera Yoen
@Heera_Yoen · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 10, 2022 · 24 shares · 111 followers View post →
Julia Hileman
@Jkhileman · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 10, 2022 · 21 shares · 181 followers View post →
Vance Forte
@vrforte · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 10, 2022 · 24 shares · 447 followers View post →
Nevin de Korompay
@NevdeK · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 10, 2022 · 24 shares · 783 followers View post →
Debkumar Sarkar
@debkumarsarkar · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 764 followers View post →
Julie Fung
@fung_julie · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 283 followers View post →
Cain
@IR_Cain · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 368 followers View post →
Nevin de Korompay
@NevdeK · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 783 followers View post →
AileenOShea
@AileenO_Shea · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 300 followers View post →
The Arab Journal of Interventional Radiology
@Arabjir · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 1,522 followers View post →
Kareem Elfatairy
@kareemfatairy · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 385 followers View post →
Kelly N Davis, DO
@kellyndavis · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 157 followers View post →
Hassan ALQarni, MD حسن القرني
@Qarnihassan4 · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 924 followers View post →
Rene Sarria
@ReneSarria · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 75 followers View post →
Dr Sunil Kalmath MD EBIR
@DrLighthunter · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 1,243 followers View post →
Mickael Tordjman, MD
@Mike_tordjman · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 307 followers View post →
Dr Sachin Modi
@interadiologist · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 853 followers View post →
Dr Sunil Kalmath MD EBIR
@DrLighthunter · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 1,243 followers View post →
Vance Forte
@vrforte · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 447 followers View post →
Chris Malone
@ChrisDMaloneVIR · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 475 followers View post →
University of Arizona VIR
@ArizonaVIR · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 1,460 followers View post →
AmmarSarwarIRad
@AmmarSarwarIRad · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 758 followers View post →
Sidhartha Tavri, MBBS DABR FSIR
@SidTavri · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 890 followers View post →
Pankaj Kaushal
@PankajKaushalMD · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 838 followers View post →
Austin Bourgeois
@AustinBourgeois · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 6,966 followers View post →
Harjit Singh
@hsinghIR · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 651 followers View post →
Mohammed Faisal Loya, M.D.
@DrFLoya · X

RT @NorthwesternIR: TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesoc…

Mar 9, 2022 · 21 shares · 1,612 followers View post →
NorthwesternIR
@NorthwesternIR · X

TRACE trial out: Y90 outperforms DEBs in BCLC A/B HCC. Sig better TTP + OS. Level I evidence RCT @riadsalemIR @cirsesociety @AASLDtweets @EASLnews @SIRspecialists @ASTRO_org @radiology_rsna @JVIRmedia @bsc_io @SirtexMedical @RSNA https://t.co/kNiVrTpmXl

Mar 9, 2022 · 74 likes · 21 shares · 3,757 followers View post →
Linda Tutty
@LindaTutty · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 730 followers View post →
Cynthia De la Garza, MD
@cyndlg · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 1,857 followers View post →
Alex J. Solomon, MD
@alexjsolomonIR · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 316 followers View post →
Francis Deng, MD
@francisdeng · X

RT @RyanWEngland: Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phas…

Mar 9, 2022 · 24 shares · 16,963 followers View post →
Ryan England, MD
@RyanWEngland · X

Yttrium-90 radioembolization vs. chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phase 2 randomized controlled trial. #InAMinute @RadiologyEditor #RadInTraining @RadITrainEditor @radiology_rsna

Mar 9, 2022 · 67 likes · 24 shares · 1,044 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: 90Y Radioembolization versus Drug-eluting Bead Chemoembolization for Unresectable Hepatocellular Carcinoma: Results from the TRACE Phase II Randomized Controlled Trial https://t.co/I2b10sS9cS #livercancer #oncology https://t.co/7lR2v0UY8q

Mar 8, 2022 · 891 followers View post →
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