BMC Microbiol March 2022 PMID 35287577

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides.

Gajender Aleti, Jordan N Kohn, Emily A Troyer, Kelly Weldon, Shi Huang, Anupriya Tripathi, Pieter C Dorrestein, Austin D Swafford, Rob Knight, Suzi Hong

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Mentions

9
Peak: 5 in Mar 2022
across 2 sources since Aug 2021

Extended reach

26,527
potential audience

Total likes

2

Video views

366

Mentions per month

Aug 2021 – May 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos

AI synopsis

What people are saying

Overall, the discussions express strong interest and moderate engagement, with posts referencing the study’s focus on oral bacteria differences in obesity and depression, as well as implications for inflammation treatment. Words like 'different,' 'importance,' and hashtags like '#ScientificArticles' highlight both curiosity and recognition of its potential significance, but without deep dives into the methodology or broader implications.

AgreementModerate agreement

Most discussions recognize the significance of the study, emphasizing the links between oral bacteria, depression, and obesity, reflecting broad agreement on its relevance.

InterestHigh interest

The use of terms like 'new study,' 'novel insights,' and hashtags suggests high curiosity and engagement with the scientific findings.

EngagementModerate engagement

Participants reference specific aspects such as inflammation and oral microbiome management, indicating moderate depth in their discussion, but mostly highlighting the importance rather than detailed critique.

ImpactModerate impact

The discussions suggest that this research could influence future approaches to managing depression and obesity through microbiome-related interventions, indicating potential impact.

Abstract in brief

  • The study found that specific oral bacteria and their neuroactive metabolites are linked to depression, obesity, and their co-occurrence, with Gram-negative bacteria being more prevalent in people with both conditions and supporting an inflammation connection.
  • Metabolomic analysis showed changes in signaling molecules, amino acids, and neuropeptides associated with these conditions, indicating that the microbiome may influence brain-related processes through neuroactive compounds.
  • Integrating microbiome and metabolomics data suggests that oral microbes may produce neuroactive substances like dopamine, serotonin, and epinephrine precursors, highlighting a potential microbial-brain communication pathway involved in depression and obesity.]

Top posts

Most liked on X and Bluesky
medRxiv
@medrxivpreprint · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/PJXE4qhyAj #medRxiv

Aug 12, 2021 · 2 likes · 17,452 followers View post →
Dr Nagina Khan
@DrKhan_do · X

RT @BMC_series: Suzi Hong and co-authors have published in #BMCMicrobiol a study reporting novel insights into oral microbial-brain connect…

Mar 23, 2022 · 1 share · 6,295 followers View post →
Symbiosis papers
@Symbiosispapers · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/2199I3wvII

Mar 15, 2022 · 1,104 followers View post →
MyJournals
@myjournals · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/sTy7OaMLEx

Mar 14, 2022 · 550 followers View post →
Ross Perry
@oliverrossperry · X

A new study reports the bacterial mix of saliva differs in obese and depressed adults. https://t.co/0YW3nPSgvn Obesity and depression are driven by inflammation. Gum disease lifts inflammation by 20%. So managing the oral microbiome with Prevora becomes even more important. https://t.co/Y0MPiSktzr

Aug 12, 2022 · 524 followers View post →
Lorena Abadía-Patiño Asesora en Microbiología
@AbadiaEn · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/T1ibFbUmGp

Mar 16, 2022 · 216 followers View post →

All mentions

Ross Perry
@oliverrossperry · X

A new study reports the bacterial mix of saliva differs in obese and depressed adults. https://t.co/0YW3nPSgvn Obesity and depression are driven by inflammation. Gum disease lifts inflammation by 20%. So managing the oral microbiome with Prevora becomes even more important. https://t.co/Y0MPiSktzr

Aug 12, 2022 · 524 followers View post →
Dr Nagina Khan
@DrKhan_do · X

RT @BMC_series: Suzi Hong and co-authors have published in #BMCMicrobiol a study reporting novel insights into oral microbial-brain connect…

Mar 23, 2022 · 1 share · 6,295 followers View post →
CMI Publications
@CMIpublications · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides | BMC Microbiology #CMImember #ScientificArticles #JournalArticles https://t.co/B1GZry3a1w

Mar 18, 2022 · 19 followers View post →
Lorena Abadía-Patiño Asesora en Microbiología
@AbadiaEn · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/T1ibFbUmGp

Mar 16, 2022 · 216 followers View post →
Symbiosis papers
@Symbiosispapers · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/2199I3wvII

Mar 15, 2022 · 1,104 followers View post →
MyJournals
@myjournals · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/sTy7OaMLEx

Mar 14, 2022 · 550 followers View post →
medRxiv
@medrxivpreprint · X

Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides https://t.co/PJXE4qhyAj #medRxiv

Aug 12, 2021 · 2 likes · 17,452 followers View post →