The collective discussions demonstrate strong support and curiosity, with posts highlighting the importance of weakened neural connections in at-risk youth and their implications for bipolar disorder, using words like 'impressive,' 'important,' and emphasizing the potential for advances in diagnosis and understanding resilience, which shows both high interest and perceived impact.
AgreementModerate agreement
Most discussions acknowledge the importance of the research and support its findings around neural differences in high-risk individuals.
InterestHigh interest
The discussions reflect high interest, highlighted by the enthusiasm in phrases like 'impressive and important work' and detailed summaries of neural changes.
EngagementModerate engagement
Several posts engage deeply by referencing specific brain regions, neural networks, and potential implications for understanding resilience and disease onset.
ImpactHigh impact
The discussions emphasize the significance of the findings for future research and clinical applications, suggesting high potential impact.
Abstract in brief
The study investigated how brain connectivity changes over two years in young people at high genetic risk for bipolar disorder compared to controls, using MRI data.
Both groups showed overall brain network development, but high-risk individuals experienced specific weakening in certain brain regions related to emotion and cognition, which persisted or worsened over time.
These differences in brain network development might help explain why some high-risk individuals develop bipolar disorder, highlighting the importance of neurodevelopmental processes in illness onset and resilience.]
“Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder” by Philip Mitchell et al. American Journal of Psychiatry
https://t.co/f9gPvE8t2L
Mar 28, 2022 · 9 likes · 3 shares · 506,664 followersView post →
SF
Stefan Frässle
@stefan_fraessle · X
"Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder" in The American Journal of Psychiatry -- impressive and (clinically) important work by @alistairgperry @DrBreaky and others https://t.co/DhSKVZBjtl
Mar 30, 2022 · 8 likes · 4 shares · 2,199 followersView post →
JA
Journals of The American Psychiatric Association
@APAPubJournals · X
From @UNSW Sydney, individuals at high risk of bipolar disorder exhibit differences in maturational processes in a multisystem network in the brain. This represents a chance for understanding resilience and predicting conversion to bipolar disorder.
https://t.co/FJjOJHhOhD
May 13, 2022 · 4 likes · 2 shares · 11,607 followersView post →
JA
Journals of The American Psychiatric Association
@APAPubJournals · X
From @UNSW Sydney, individuals at high risk of bipolar disorder exhibit differences in maturational processes in a multisystem network in the brain. This may represent a chance for understanding resilience + predicting conversion to bipolar disorder. 3/4
https://t.co/MQ1h1Ma1e3
May 24, 2022 · 2 likes · 1 share · 11,607 followersView post →
JA
Journals of The American Psychiatric Association
@APAPubJournals · X
AJP Deputy Editor Danny Pine highlights two articles from the July 2022 issue.
https://t.co/SpwtXwT0xZ
The study investigated how brain connectivity changes over two years in young people at high genetic risk for bipolar disorder compared to controls, using MRI data. Differences in neural development may explain…
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses a study on digital interventions for cognitive deficits in major depression, reviewing efficacy and safety in adults. The video highlights…
The study investigates how brain connectivity evolves over two years in young individuals at high genetic risk for bipolar disorder versus controls, revealing specific weakening in emotion and cognition-related regions…
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses a study examining how brain connectivity evolves over two years in young people at high genetic risk for bipolar disorder. The research highlights…
Scans show weakened connections in brains of adolescents at risk of bipolar disorder
https://t.co/2VAIPCw5t0
https://t.co/DF0E5MmSjU https://t.co/OCv3On2Xcw
From @UNSW Sydney, individuals at high risk of bipolar disorder exhibit differences in maturational processes in a multisystem network in the brain. This may represent a chance for understanding resilience + predicting conversion to bipolar disorder. 3/4
https://t.co/MQ1h1Ma1e3
May 24, 2022 · 2 likes · 1 share · 11,607 followersView post →
VV
Verónica VQuer
@VeronicaVquer · X
RT @APAPubJournals: From @UNSW Sydney, individuals at high risk of bipolar disorder exhibit differences in maturational processes in a mult…
From @UNSW Sydney, individuals at high risk of bipolar disorder exhibit differences in maturational processes in a multisystem network in the brain. This represents a chance for understanding resilience and predicting conversion to bipolar disorder.
https://t.co/FJjOJHhOhD
May 13, 2022 · 4 likes · 2 shares · 11,607 followersView post →
Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder.
El neurodesarrollo desde la adolescencia-adultez temprana está asociado con reorganización sustancial de las redes cerebrales estructurales.
https://t.co/NKDB3aO02N
Mar 31, 2022 · 1 like · 2,785 followersView post →
EM
Emiliano MQ
@NANOxMQ · X
Weakened Connections in Brains of Young People at Risk of Bipolar Disorder
https://t.co/g879sT7qaJ
RT @stefan_fraessle: "Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder" in The Ame…
Mar 30, 2022 · 4 shares · 252 followersView post →
TW
Thomas Wolfers
@ThomasWolfers · X
RT @stefan_fraessle: "Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder" in The Ame…
Mar 30, 2022 · 4 shares · 870 followersView post →
WC
Wendy Burn CBE
@wendyburn · X
RT @stefan_fraessle: "Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder" in The Ame…
Mar 30, 2022 · 4 shares · 27,298 followersView post →
SF
Stefan Frässle
@stefan_fraessle · X
"Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder" in The American Journal of Psychiatry -- impressive and (clinically) important work by @alistairgperry @DrBreaky and others https://t.co/DhSKVZBjtl
Mar 30, 2022 · 8 likes · 4 shares · 2,199 followersView post →
MH
Mar Alonso Hoyas
@MarMarhoyas · X
RT @NeuroscienceNew: “Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder” by Philip…
Mar 29, 2022 · 3 shares · 3,650 followersView post →
P
Progress
@progressnp · X
People with a high-risk phenotype for bipolar disorder show weakened connectivity in executive and cognitive control networks in the final stages of neurodevelopment compared to controls, approaching a phenotype seen in established bipolar disorder: https://t.co/QCs6mVpLZB
Bipolar bozukluk geliştirme riski yüksek olan gençler üzerinde yapılan bir beyin görüntüleme çalışması, ilk kez geç ergenlik döneminde beynin kilit alanları arasındaki bağlantıların zayıfladığına dair kanıt buldu.
#bipolar #psikiyatri #psikoloji #beyin
https://t.co/mAEeEfhU0O https://t.co/GYEdikLd8O
RT @NeuroscienceNew: “Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder” by Philip…
Mar 28, 2022 · 3 shares · 11,750 followersView post →
NN
Neuroscience News
@NeuroscienceNew · X
“Longitudinal Changes in Structural Connectivity in Young People at High Genetic Risk for Bipolar Disorder” by Philip Mitchell et al. American Journal of Psychiatry
https://t.co/f9gPvE8t2L
Mar 28, 2022 · 9 likes · 3 shares · 506,664 followersView post →
JA
Journals of The American Psychiatric Association
@APAPubJournals · X
From @UNSW Sydney, individuals at high genetic risk of bipolar disorder exhibit differences in maturational processes in a multisystem network in the brain. This represents a novel understanding of resilience and predicting conversion to bipolar disorder. https://t.co/FJjOJHhOhD https://t.co/UKTNbjXfhR
Mar 28, 2022 · 1 like · 1 share · 11,607 followersView post →
N
Differences in neurodevelopmental maturation indicate higher risk ...
News
Am J Psychiatry. 2022;doi: 10.1176/appi.ajp.21010047. Disclosures: Roberts reports no relevant financial disclosures. Please see the study for ...