Front Neurosci March 2022 PMID 35368252

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains.

Fabrízio Dos Santos Cardoso, Douglas W Barrett, Zachary Wade, Sérgio Gomes da Silva, F Gonzalez-Lima

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Mentions

14
Peak: 3 in Apr 2022
across 4 sources since Apr 2022

Extended reach

28,492
potential audience

Total likes

25

Video views

149

Mentions per month

Apr 2022 – Jun 2025

Where it's discussed

  • X / Twitter8 posts
  • YouTube2 videos
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Discussions exhibit strong interest by referencing concepts like dawn sunlight's alignment with CCO absorption and highlighting the restorative effects of laser stimulation on aging brains, using technical language and positive tone. The focus on mechanisms like antioxidant enzyme upregulation and brain activity modulation demonstrates curiosity and moderate engagement, though the tone remains informational rather than critical or skeptical.

AgreementModerate agreement

Most discussions acknowledge the promising effects of laser therapy on brain aging, reflecting moderate support.

InterestHigh interest

Participants show high curiosity about how light wavelengths and laser stimulation could influence brain health, evidenced by technical references.

EngagementModerate engagement

Comments indicate some level of engagement through mentions of biological mechanisms and potential benefits, though not deeply debated.

ImpactModerate impact

While the discussions suggest potential applications, they remain somewhat speculative without strong calls to action or concrete evidence presented by users.

Abstract in brief

  • This study investigates how chronic transcranial laser photobiomodulation (PBM) affects cytochrome c oxidase (CCO) activity in the brains of young and aged rats, showing that aging decreases CCO activity and brain connectivity, but PBM can reverse these age-related declines.
  • The research involves detailed brain mapping and compares CCO activity in rats that received laser stimulation over 58 days with controls, finding that PBM restores CCO activity levels in aged rats to those similar to young rats.
  • Since CCO plays a key role in brain energy production, these findings suggest that PBM could potentially improve brain function and energy metabolism in older individuals, helping to mitigate age-related cognitive decline.

Top posts

Most liked on X and Bluesky
Fez☯️
@Zenfrog4 · X

What Makes Sunrise Unique? Dawn sunlight peaks at 660 nm (red) and 850mm (NIR), aligning with CCO's absorption maxima. https://t.co/xGW7HjlI1i And, as mentioned, morning light pulses generate transient singlet oxygen, which: - Upregulates antioxidant enzymes (SOD, catalase) https://t.co/TJIEf7xqum

Apr 14, 2025 · 7 likes · 2 shares · 3,102 followers View post →
Rene Sugar
@renesugar · X

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains https://t.co/PD0q3MEbwh

Jan 11, 2023 · 2 likes · 3,959 followers View post →
Ken Gusler
@kgusler · X

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains: https://t.co/lJVFsoCbbO

Apr 10, 2022 · 20,039 followers View post →
alephh
@alephh · X

Photobiomodulation of Cytochrome-c-Oxidase by Chronic Transcranial Laser in Young/Aged Brains — Aging decreased regional brain CCO activity & systems-level functional connectivity, while chronic laser stimulation predominantly reversed age-related effects https://t.co/bWLmkLYdkh

Apr 12, 2022 · 388 followers View post →
Reddit Journal of Science
@rsciencejournal · X

1/ Application of light in the near-infrared spectrum to the skull may be used to augment brain and behavioral functions of older individuals by improving oxidative energy metabolism. https://t.co/ZsUSnIHXYX #science #medicine

Apr 10, 2022 · 332 followers View post →
Pieter Janssens
@pieter_mj_j · X

RT @Zenfrog4: What Makes Sunrise Unique? Dawn sunlight peaks at 660 nm (red) and 850mm (NIR), aligning with CCO's absorption maxima. http…

Apr 15, 2025 · 2 shares · 287 followers View post →

All mentions

Silvia de Dios
@SilviadeDios12 · X

RT @Zenfrog4: What Makes Sunrise Unique? Dawn sunlight peaks at 660 nm (red) and 850mm (NIR), aligning with CCO's absorption maxima. http…

Apr 15, 2025 · 2 shares · 222 followers View post →
Pieter Janssens
@pieter_mj_j · X

RT @Zenfrog4: What Makes Sunrise Unique? Dawn sunlight peaks at 660 nm (red) and 850mm (NIR), aligning with CCO's absorption maxima. http…

Apr 15, 2025 · 2 shares · 287 followers View post →
Fez☯️
@Zenfrog4 · X

What Makes Sunrise Unique? Dawn sunlight peaks at 660 nm (red) and 850mm (NIR), aligning with CCO's absorption maxima. https://t.co/xGW7HjlI1i And, as mentioned, morning light pulses generate transient singlet oxygen, which: - Upregulates antioxidant enzymes (SOD, catalase) https://t.co/TJIEf7xqum

Apr 14, 2025 · 7 likes · 2 shares · 3,102 followers View post →
Rene Sugar
@renesugar · X

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains https://t.co/PD0q3MEbwh

Jan 11, 2023 · 2 likes · 3,959 followers View post →
John Paruch
@johnparuchmd · X

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains https://t.co/8hup6DdTD4 #PBM #coldlasertherapy

Oct 14, 2022 · 3 followers View post →
alephh
@alephh · X

Photobiomodulation of Cytochrome-c-Oxidase by Chronic Transcranial Laser in Young/Aged Brains — Aging decreased regional brain CCO activity & systems-level functional connectivity, while chronic laser stimulation predominantly reversed age-related effects https://t.co/bWLmkLYdkh

Apr 12, 2022 · 388 followers View post →
Reddit Journal of Science
@rsciencejournal · X

1/ Application of light in the near-infrared spectrum to the skull may be used to augment brain and behavioral functions of older individuals by improving oxidative energy metabolism. https://t.co/ZsUSnIHXYX #science #medicine

Apr 10, 2022 · 332 followers View post →
Ken Gusler
@kgusler · X

Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains: https://t.co/lJVFsoCbbO

Apr 10, 2022 · 20,039 followers View post →