Overall, the discussions reflect a strong interest in the implications for clinical practice, citing specific data such as 25% leak rate at follow-up and the increased thromboembolic risk with small leaks, which indicates active engagement. The tone is analytical, emphasizing procedural accuracy and patient outcomes, demonstrating a moderate but meaningful potential impact on clinical decision-making.
AgreementModerate agreement
Most discussions support the findings that small residual leaks (0-5mm) are linked with increased risks, but larger leaks (>5mm) do not correlate with adverse events, indicating agreement with the study conclusions.
InterestHigh interest
Posts demonstrate high interest, referencing specific data percentages and clinical implications, showing engagement with the research details.
EngagementModerate engagement
Several discussions reference clinical implications, follow-up data, and imaging techniques, indicating a moderate level of deep engagement.
ImpactModerate impact
The discussions highlight the importance of residual leak assessment and procedural techniques, suggesting the findings could influence clinical practice and device management.
Abstract in brief
The study analyzed data from over 51,000 patients who underwent left atrial appendage occlusion (LAAO) to see if residual leaks after the procedure affect health outcomes, finding that small leaks (0.5mm) are linked with slightly increased risks of stroke, bleeding, and adverse events.
Patients with larger leaks (5mm) did not experience more adverse events, but they were more often kept on blood-thinning medications like warfarin; smaller leaks still had some increased risk compared to no leaks.
The findings suggest that smaller leaks might modestly increase risks, but newer devices with better sealing could reduce problems related to residual leaks after LAAO.]
Small Peri-Device Leak (≤ 5mm) after LAAO are Associated with ⬆️ Thromboembolic Events at 1-Year. #ACC22 https://t.co/fFNFigzQW3 https://t.co/6yu6TG3bxM
Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic & bleeding events
* >5mm leaks were rare (<1%) & not associated w/ adverse events, but more were maintained on #anticoagulation. https://t.co/qdZLiyLzve #JACCCEP https://t.co/xjFHJ5hnWd
Jun 30, 2022 · 66 likes · 34 shares · 115,495 followersView post →
R
RTHahnMD
@hahn_rt · X
New Data on Followup & Outcomes of PeriDevice Leak (PDL) following LAA Occlusion: https://t.co/Q9LiuWg184 &
https://t.co/6ISsjmvpiN Essential to avoid PDL!
@VUMC_heart @davidrholmes2 @adnanalkhouli @drpaulfriedman @JACCJournals @ACCinTouch @ASE360 #LAA @VivekReddyMD @brijmaini https://t.co/SpqUkx8712
✨#ACC22 LBCT✨
Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion: Insights From the NCDR #LAAO Registry
➡️ 25% had leak at 45d f/u
➡️ Leaks <= 5mm ➡️ 10-15% ⬆️ TE / bleeding event at 1y
#SimPub #JACCCEP @JACCJournals
https://t.co/fnZ0cECZlz #EPeeps https://t.co/HSy9f9EmHk
Given the recent NCDR manuscript https://t.co/6ISsjmN0al on importance of eliminating PDL, is intraprocedural ICE imaging comprehensive enough compared to TEE which allows a 360 degree evaluation? @adnanalkhouli @VivekReddyMD @brijmaini @davidrholmes2 @ACCinTouch @JACCJournals https://t.co/t1VKuthS8D https://t.co/KMPNiWyLfx
This episode discusses the evolving evidence behind left atrial appendage occlusion, reviewing pivotal trials like PROTECT, PREVAIL, and the upcoming CHAMPIONAF at ACC 2026, highlighting safety, efficacy, and future…
Mohamad Alkhouli summarizes a study analyzing data from over 51,000 patients undergoing left atrial appendage occlusion, highlighting that small residual leaks may modestly increase risks of stroke and bleeding, while…
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 1,829 followersView post →
JG
Jose Juan García
@2jeystone · X
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 163 followersView post →
MP
Manuel Barreiro-Perez
@manuelbarreirop · X
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 1,873 followersView post →
Q
Quique
@Quiquemonjes · X
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 93 followersView post →
CI
Carlos E. Izurieta
@Dardinho83 · X
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 304 followersView post →
AJ
Alessandra Joslin
@AleJoslin · X
Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion: Insights From the NCDR LAAO Registry | JACC: Clinical Electrophysiology https://t.co/v1BiOKWQLm
RT @JACCJournals: Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic &…
Jun 30, 2022 · 34 shares · 6,405 followersView post →
JJ
JACC Journals
@JACCJournals · X
Clinical Impact of Residual Leaks Following #LAAO: #NCDR-LAAO Registry
* 0-5mm leaks had slightly ⬆️er thromboembolic & bleeding events
* >5mm leaks were rare (<1%) & not associated w/ adverse events, but more were maintained on #anticoagulation. https://t.co/qdZLiyLzve #JACCCEP https://t.co/xjFHJ5hnWd
Jun 30, 2022 · 66 likes · 34 shares · 115,495 followersView post →
DZ
Dr. Zhong
@pzhong2016 · X
RT @adnanalkhouli: Small Peri-Device Leak (≤ 5mm) after LAAO are Associated with ⬆️ Thromboembolic Events at 1-Year. #ACC22 https://t.co/fF…
May 17, 2022 · 68 shares · 3,140 followersView post →
FM
Farid Khan MD
@KhanFaridMD · X
Wonderful work by Dr @adnanalkhouli and his team on the peri-device leaks post LAAO.
Small leaks >0-5mm were found in 25% in a cohort of >50K patients in LAAO registry, associated with higher VTE and bleeding events compared to leaks >5mm. @jaccjournals
https://t.co/OSYGru531b
SCAI expert @AGoldsweig covers trial presented at #ACC22: Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion: Insights From the NCDR LAAO Registry https://t.co/JZszvJvRLY https://t.co/5fArRY2s7a
Given the recent NCDR manuscript https://t.co/6ISsjmN0al on importance of eliminating PDL, is intraprocedural ICE imaging comprehensive enough compared to TEE which allows a 360 degree evaluation? @adnanalkhouli @VivekReddyMD @brijmaini @davidrholmes2 @ACCinTouch @JACCJournals https://t.co/t1VKuthS8D https://t.co/KMPNiWyLfx
"0-5 mm leaks after LAAO were associated with modestly higher incidence of thromboembolic/bleeding events; >5 mm leaks were not associated with adverse events, although higher proportions of these patients were maintained on anticoagulation"
https://t.co/PN2hZZypPa https://t.co/0WXnHngjoG
Small Peri-Device Leak (≤ 5mm) after LAAO are Associated with ⬆️ Thromboembolic Events at 1-Year. #ACC22 https://t.co/fFNFigzQW3 https://t.co/6yu6TG3bxM
✨#ACC22 LBCT✨
Clinical Impact of Residual Leaks Following Left Atrial Appendage Occlusion: Insights From the NCDR #LAAO Registry
➡️ 25% had leak at 45d f/u
➡️ Leaks <= 5mm ➡️ 10-15% ⬆️ TE / bleeding event at 1y
#SimPub #JACCCEP @JACCJournals
https://t.co/fnZ0cECZlz #EPeeps https://t.co/HSy9f9EmHk
Left atrial appendage occlusion: Contemporary review and current ...
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