The discourse centers on the STEP 1 extension findings that two-thirds of lost weight returned within a year after withdrawal, with cardiometabolic gains waning. Respondents range from neutral observers to critical voices arguing for lifelong treatment or lifestyle changes, with many citing the paper to push for sustained management of obesity. The language spans neutral summaries, critiques, questions, and advocacy, reflecting a broad, somewhat skeptical but highly engaged discussion about the implications of the study for obesity treatment and health policy.
AgreementNeither agree nor disagree
Overall, posts show mixed to cautious agreement; many acknowledge findings but few express strong endorsement or rejection of GLP-1 therapies as a long-term solution.
InterestModerate interest
Moderate to high interest; numerous posts cite the study and discuss implications, indicating engagement with the topic.
EngagementModerate engagement
Engaged discussions with critical takes, questions, and calls for data beyond the paper; some sarcasm and campaigning tones.
ImpactModerate impact
Notable potential impact on opinions about long-term GLP-1 use; discussions emphasize need for lifestyle changes and ongoing treatment, suggesting moderate to high perceived impact.
Abstract in brief
The STEP 1 trial assessed the effects of subcutaneous semaglutide on weight loss and cardiometabolic risk factors in adults with obesity over 68 weeks, followed by a one-year treatment withdrawal phase.
Participants experienced significant weight loss with semaglutide, averaging a 17.3% reduction, while those on placebo lost only 2.0%, but most regained a substantial portion of this weight after stopping treatment.
Results indicated that cardiometabolic health improvements also declined after treatment ended, suggesting long-term care is essential for sustaining weight loss and health benefits.
A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatment. Some interesting things to chew on in this paper.
h/t @kamleshkhunti
https://t.co/eCaOObyIk6
May 11, 2022 · 136 likes · 32 shares · 48,844 followersView post →
E
endocrinorosero
@endocrinorosero · X
Historia real :
(Es de la mamá de un compañero de mi hijo)
Tiene sobrepeso y fue atendida por cuenta de su servicio de salud por un Endocrino
El Endocrino le dice:
Como tiene exceso de peso tiene dos opciones
1. Se inyecta este medicamento.
O
2. Se hace la cirugía https://t.co/iUA7a6H5ZF
Nov 19, 2024 · 114 likes · 34 shares · 168,221 followersView post →
I
IberianCitizen
@IberianCitizen · X
Pincharse no enseña a comer, ni vale para siempre, aprovechar el tirón y seguir con los hábitos
The Ozempic boom is just another case in point. When people stop taking it, as they do in the vast majority of cases due to its costs and side effects, the weight comes roaring back. WW keeps profiting on the same old model https://t.co/ZzD6V2DMSW https://t.co/KKWUT2nfzz
Dec 16, 2023 · 50 likes · 8 shares · 45,399 followersView post →
A
Alvin
@alvie_barr · X
Ozempic/Wegovy are all over the news & a lot of misconceptions
Here’s a trial on what happens when treatment is stopped
Link: https://t.co/OAnAscAvFP https://t.co/4ylTq0fLH5
@aschleighj2022 When they stop taking it, as do the vast majority of patients, the weight comes roaring back--setting people up for weight cycling, which is independently harmful to our health https://t.co/ZzD6V2DMSW
Dec 16, 2023 · 43 likes · 1 share · 45,399 followersView post →
This study examines how patients with type 2 diabetes in the UK stick to and benefit from GLP1 receptor agonists. About 54% achieved at least 5% weight loss at 12 and 24 months, but discontinuation was common…
Explores weight loss from semaglutide in obesity over 68 weeks and how most of the gains fade during a 1-year withdrawal, with diminishing cardiometabolic benefits. Highlights the need for ongoing care to sustain health…
This video discusses the effects of Ozempic on the body after nine months, highlighting ongoing research and developments in weight loss medications, with insights from Abbey Sharp and updated medical information.
This video exposes the harmful misinformation spreading about Ozempic online. It discusses the impact of marketing strategies, potential side effects, and shares simple, side effect-free hacks to enhance health…
Examines rapid weight loss claims from Ozempic and explains potential risks, including long-term sustainability and health considerations beyond initial weight reduction.
Weight loss drugs Ozempic, Wegovy, and Mounjaro are discussed, covering how they work and their safety. This video explains their roles as GLP1 mimetics for obesity and weight management.
A new drug achieves 24% body weight loss and improves blood pressure, glucose, triglycerides, and cholesterol. It is important to understand how retatrutide works and potential downsides, as these medications may…
This video explores the impact of Ozempic, a GLP-1 receptor agonist, on weight management. It discusses potential benefits and concerns regarding muscle loss, supported by recent research studies, to inform viewers…
Delves into the GLP-1–based drugs semaglutide and related compounds, their duration in blood, and concerns about pancreatitis, ocular risks, and unsupervised cosmetic use.
This video explores recent research on fatty liver disease, focusing on GLP1 medications, diet, and exercise's role in management, and the importance of ongoing care for sustained health improvements.
Comprehensive look at semaglutide: mechanism, indications, dosing, side effects, contraindications, and safety considerations for clinical use and exams.
This episode addresses myths and realities surrounding Ozempic and GLP-1 receptor agonists. We explore findings from the SUSTAIN 8 study, which highlights significant reductions in total fat mass with semaglutide…
This video explores how Semaglutide, marketed as Ozempic or Wegovy, functions as a weight loss aid, examining its potential benefits and associated risks based on scientific research and recent FDA approvals.
The STEP 1 trial evaluated weight loss and cardiometabolic health with semaglutide, revealing significant initial improvements that declined upon treatment discontinuation, emphasizing the need for ongoing management…
Learn about science-backed strategies for long-term weight loss and maintenance from Dr. Laurena Law, including lifestyle changes, medications, and innovative technology to support weight management.
The fake Ozempic jab can cause hypoglycaemic shock and comas. This video explains drug origins, how it promotes weight loss, and what happens when treatment stops, including potential weight regain and health effects.
Discusses how obesity meds can reduce fat but also muscle, affecting metabolism, with about 30% of weight loss from muscle and potential rebound fat after stopping.
Why does losing weight often make you feel hungrier and why is it so hard to keep the weight off? This video explains the science behind the body's counterattack against weight loss, set point theory, and the roles of…
In this video, we discuss the use of weight-loss injections and their potential to revolutionize obesity treatment versus industry-promoted promises. We examine scientific insights on GLP-1 hormones and recent research…
Traces how Ozempic and Mounjaro were developed, why Paraguay is discussed for purchases, and how Brazil's SUS and CONITEC respond as Ozivy enters the market.
Explains how semaglutide alters appetite and weight loss, why it lasts a week in blood, common side effects, and what happens after stopping treatment.
This video explores the role of GLP-1 receptor agonists in addressing obesity and other health issues. It reviews recent innovations, their effectiveness in treating obesity, heart disease, and neurodegenerative…
Obesity and Type 2 diabetes are rising globally, often managed with diet, blood sugar monitoring, and pharmaceuticals. While GLP-1 receptor agonists show promise in controlling blood sugar and promoting weight loss…
GLP1 medications are making headlines but what do they actually mean for your longterm health energy and relationship with food. This episode explores how these drugs affect the body beyond weight, including muscle…
Explore the effectiveness of GLP-1 drugs like Ozempic, Wegovy, and Mounjaro for weight loss, with up to 20% reduction. Learn how they work, potential side effects, and long-term impact. Discover who benefits most and…
Explains what peptides are and reviews weight loss, immunity, and healing/fitness peptides. Discusses claims, risks, and evidence, emphasizing that this is informational and not medical advice.
The STEP 1 trial evaluated subcutaneous semaglutide's effects on weight loss and cardiometabolic risk factors over 68 weeks, followed by a one-year withdrawal. Participants experienced significant weight loss and health…
Si está buscando un método para bajar de peso y en redes le dicen que lo puede conseguir solo con alimentación y/o otras personas solo con medicamentos, tal vez le están contando la mitad de la historia.
Lea este artículo para entender mejor. https://t.co/A7A8QICpLQ
Oct 21, 2026 · 6 likes · 12,738 followersView post →
小公
小澤栄治 米国自然療法医（ND）公式
@shizenryouhou · X
https://t.co/ivv7TmaZfp
Oct 20, 2026 · 4 likes · 3,096 followersView post →
CH
Clyr Health
@ClyrHealth · X
@semodough This is the real problem in obesity care. In the STEP 1 extension, people regained about two-thirds of their lost weight within a year of stopping semaglutide (Wilding 2022, DOI 10.1111/dom.14725). Anything that helps people hold the loss after GLP-1s is worth watching.
Po odstawieniu semaglutydu wracają nie tylko kilogramy. W przedłużeniu badania STEP 1, rok po zakończeniu leczenia i programu stylu życia, większość poprawionych parametrów kardiometabolicznych wróciła w stronę wartości wyjściowych.
Źródło: Wilding J.P.H. i wsp., „Weight regain
Not a health expert but I’d suggest going about it the old fashioned way diet and exercise. Using glp 1’s isn’t effective because you will regain most of what you lose if you get off them. https://t.co/VdNJUxkybD https://t.co/3hkOWMm9i5
Canetas emagrecedoras no SUS: entre a lógica econômica e o desenho da política
Um ensaio sobre custo-efetividade, impacto orçamentário e governança no anúncio da incorporação de semaglutida pelo SUS — setembro de 2026
1. A pergunta certa
Em 17 de setembro de 2026, o presidente
@MWeintraubMD Two-thirds of it, numerically: in the STEP 1 extension, people who stopped semaglutide at week 68 had lost 17.3% and regained 11.6 points a year later, netting 5.6%. Cardiometabolic gains reverted too. The defended fat mass doesn't care. https://t.co/RxCJmBFb4M
Sep 12, 2026 · 1 like · 3,378 followersView post →
MN
Metabolic Nurse
@metabolicnurse · X
@davidludwigmd In the STEP 1 extension, weight loss was 17.3% at week 68; a year after withdrawal two-thirds of it came back and cardiometabolic gains reverted (exploratory, n=327). That's the bar a diet-plus-GLP-1 comparison has to clear. https://t.co/RxCJmBFb4M
@PhoebePerkins22 @puregres no, with glp-1's, the medication itself is what’s helping maintain the weight loss, so stopping it can cause your appetite/weight to rebound even if you’re still trying to maintain those habits --> https://t.co/2Lxhb0Mwpi
@agingroy @ClevelandClinic So.. they didn’t actually “stop” everything.
There’s research that shows when they do actually “stop”, the weight rebound is very real from just these two studies:
https://t.co/oZ5KHoRtZb
https://t.co/ihlGRTCkOF
It’s pretty safe to assume that a lot if not most people may
Study 2: https://t.co/ihlGRTCkOF
A separate trial compared what happened when participants continued using semaglutide versus switching to placebo, while both groups received identical lifestyle interventions. Those who switched to a placebo gained an average of 6.9% of body
@hpassosneto "Canetinhas"
Veja só que absurdo! quantos estão se injetando sem saber destes riscos e como algo assim é liberado ao grande público, não apenas ao paciente com risco/benefício favorável?
Qual % das vendas para r/b favoráveis: 1% 5% 10%?
CADÊ OS RCT's?!?
https://t.co/sQ8jAGV9bN
Cadê as hienas perseguidoras da Dra Tatiana Sampaio, (com sua fascinante, segura e promissora molécula) que NÃO COBRARAM mais segurança destas outras moléculas via 3 ou 4 db RCT's?
e que NADA FALAM sobre a aprovação relâmpago das canetinhas ??
Canalhas!
https://t.co/Gc1ERDsmrM
@Pedrojbc92 @luiscab200 É mentira o que dizes.
Estudos mostram que a quase totalidade de quem deixa de tomar os medicamentos, acaba por recuperar dois terços do peso perdido em menos de um ano.
Ou seja, GLP-1 não é eficaz como tratamento.
https://t.co/ZABmR7oieg
@kosik_md Niestety, tak to jest jak się pełnię wiary i nadziei pokłada w leku, który ma odwalić za nas całą robotę. Znalazłem tez to samo znalezisko z 2022:
https://t.co/ChcvrKWAEX
@drdenwalker Rebound — not a good thing and they designed this so you have to be on it the rest of your life otherwise risk regaining 2/3rd of your weight back
https://t.co/EyGoXgviCC
https://t.co/wMzPj7JZpQ
Most important: https://t.co/oLbu9dq9Rh
@HeidiBriones Many patients experience rebound weight gain after discontinuing GLP-1 agonists like semaglutide,often rapid, with ~two-thirds of lost weight regained within a year (as in the STEP 1 trial extension: https://t.co/itMt1i9cJ5).
A very recent BMJ review (just published) confirms
Jan 9, 2026 · 1 like · 1 share · 1,547 followersView post →
AB
Aurora Borerealis
@let_me_atom · X
@antmcguire @LM7seven @chimpychimpy37 @anon_opin Yep, here you go chubbs. Now put down the syringe and Doritos and go for a run
https://t.co/2mQJGtcY1Q
@LShannon31734 @JebraFaushay You made me look. Found lots of articles stating that regaining weight is likely if the drug is discontinued. Looks like they're saying obesity is chronic. Justification to create a life-long dependency on this drug. ?
https://t.co/Oioyvytjia https://t.co/oLyNpOg8yX
Dec 15, 2025 · 1 like · 1,636 followersView post →
B
Brock
@InvadeCanada · X
@Biotech2k1 @inspector_token @Brandon_Job23 https://t.co/hI00VndoxU
https://t.co/uHsODTyGG2
6 month REMAIN-1 Midpoint Cohort sham controlled trial data is being released next month. They also already have 2+ year data from their Germany Real World Registry Study.
It’s going to the fucking moon.
@carolsteel82 What misinformation?
https://t.co/kNO3WlwGJM
Nov 24, 2025 · 2 likes · 11,267 followersView post →
R
Rebelcat
@graf_there52332 · X
RT @graf_there52332: Drump's REALLY BIG announcement was a reduction in weight loss drugs like Ozempic. He should read more before espousin…
Nov 6, 2025 · 3 shares · 26,679 followersView post →
S
SmalltownCouple
@Cecelia78932677 · X
RT @graf_there52332: Drump's REALLY BIG announcement was a reduction in weight loss drugs like Ozempic. He should read more before espousin…
Nov 6, 2025 · 3 shares · 6,396 followersView post →
J
Jolene
@FollowWives · X
RT @graf_there52332: Drump's REALLY BIG announcement was a reduction in weight loss drugs like Ozempic. He should read more before espousin…
Nov 6, 2025 · 3 shares · 2,448 followersView post →
R
Rebelcat
@graf_there52332 · X
Drump's REALLY BIG announcement was a reduction in weight loss drugs like Ozempic. He should read more before espousing a possibly dangerous drug that must be taken for life or weight gain returns.
https://t.co/ohEEjiCOOM
Nov 6, 2025 · 2 likes · 3 shares · 26,679 followersView post →
JM
Jeff Robinson, CEO and Chairman of $MRES and $MMAZ
@contrariansmind · X
New Fatty Liver Treatment Just Got Approved https://t.co/n0IR8rWoVY via @YouTube
@JarknCZ @zuzabkv @Pavel_Horvath @grok Existují i delší follow up studie, hledat se mi to ale nechce. Včera jsem k tomu dával náhodnou studii:
https://t.co/QBxg5JfoRr
Wilding JPH, Batterham RL, et al.
“Weight regain and cardiometabolic effects after withdrawal of semaglutide:
The STEP 1 trial extension“.
Diabetes Obes Metab. - https://t.co/RAN4mm5Ewt
dom-pubs.onlinelibrary.wiley.com/doi/10.1111/... Only marginally lower! And any improved metabolic changes revert to baseline! This is also assuming that everyone who is 'obese' on the BMI is unhealthy, which is not true! And not even considering the ethical/social implications of aesthetic use!
What happens is people gain some weight, but are still lower than start. Most people taper when dropping off, which mitigates most gains.
pubmed.ncbi.nlm.nih.gov/35441470/
@RoCoZahf Chi, justo demuestra que a pesar de su suspension la mayoria no regresa a su peso inicial
https://t.co/jc5cfKWTX3 https://t.co/tedQJfA3V8
Jun 24, 2025 · 6 likes · 9,591 followersView post →
DP
Dr. Practicón
@moy_qmac · X
@___ame___c @itsgreshi Hay ya toneladas de evidencia, llevamos ya muchos años esperando esta conclusión. A mi parecer ya se habin tardado.
https://t.co/jc5cfKWTX3
The worst part? If you stop taking Ozempic, the weight usually comes right back. One study showed most people regained 2/3 of the weight within a year of stopping.
It’s not a cure. It’s a subscription.
https://t.co/VEJe4EIIQY
RT @pash22: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension
https://t.co/7BZy6c93ZB v…
Mar 14, 2025 · 3 shares · 4,188 followersView post →
BC
Brain Food Nutrition Clinic
@anappleeveryday · X
To maintain weight loss semaglutides may need to be taken long term, likely forever.
‘One year after stopping use.. participants regained two-thirds of their weight loss …. ongoing treatment is required to maintain improvements in weight and health.’ https://t.co/rHZRMibK8h
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension
https://t.co/7BZy6c93ZB via @DrRobertKushner et al
Mar 14, 2025 · 8 likes · 3 shares · 33,658 followersView post →
B
brax
@anyamaxxed · X
@rottingwrist it's from a clinical trial that was literally funded by novo nordisk, the ozempic company.
also i'm pretty sure that if the trial had lasted longer (the chart extended longer to the right), the ozempic group would eventually converge with placebo
https://t.co/MED17iM248
Once you stop the drug, even if it was the magic drug Wegovy, weight comes back, so don't underestimate the good lifestyle maintenance.
https://t.co/olBkmUxfxU
@elonmusk
#wegovy
#ozempic
#WorldObesityDay2025
Are the results achieved with Ozempic (semaglutide) actually durable?
Given the high cost (~$1,000 monthly if not covered by insurance), potential GI side effects and inconsistent accessibility due to supply shortages, it's worth asking if the resulting weight lost stays off https://t.co/fhPXFOUyyY
Las personas que bajan de peso con semaglutida recuperan casi todo el peso luego de dejar de usarla. No hay soluciones a corto plazo.
https://t.co/MQ5LsbhyUm
Feb 4, 2025 · 13 likes · 2 shares · 6,638 followersView post →
That may be because after a year of steady weight gain - in which subjects regained on average 66% of weight lost - they quit measuring. There's no reason to think that the weight regain stopped when the study did.
pubmed.ncbi.nlm.nih.gov/35441470/
@DownedUAP @DrNadolsky Most regain some (but not all) of the weight they loss after they quit: https://t.co/TW3WhrqYIH. So there's still a net benefit for most after quitting.
Loss in muscle is not induced by the drug but weight loss in general when you don't also lift weights.
@astutelygarish It’s a bit of a boring read, but here’s a study on semaglutide which is the active ingredient in Ozempic that causes the weight loss. https://t.co/P9W12w5Avk
Jan 3, 2025 · 2 likes · 2,236 followersView post →
T
TF 2
@TonyFauci2 · X
RT @TonyFauci2: “One year after withdrawal of once-weekly subcutaneous $NVO semaglutide 2.4 mg and lifestyle intervention, participants reg…
“One year after withdrawal of once-weekly subcutaneous $NVO semaglutide 2.4 mg and lifestyle intervention, participants regained two-thirds of their prior weight loss” https://t.co/fYKcD48Awk
For 29 days after 28 day course of $VKTX VK2735 patients continued losing weight off
Jan 2, 2025 · 2 likes · 1 share · 965 followersView post →
MY
m o c h y
@mochy.bsky.social · Bluesky
4) You need to stay on them indefinitely if you don't want your health conditions and metabolic issues to reverse (unless you modify your lifestyle significantly)
@DrEenfeldt The pattern of weight gain in weight-reduced vs. non-weight-reduced people can only be explained by invoking a homeostatic reaction in weight-reduced people. They gain weight much faster than non-weight-reduced people.
https://t.co/eCaOObyauy https://t.co/gpazV5MtC9
Dec 20, 2024 · 10 likes · 1,195,011 followersView post →
RD
Rene Doo
@Rene_Doo · X
RT @Lily4Lily2: Gewichtstoename slechts 1 jaar na het stoppen met Ozempic/Wegovy.
Bevindingen bevestigen de chroniciteit van obesitas en s…
RT @Lily4Lily2: Gewichtstoename slechts 1 jaar na het stoppen met Ozempic/Wegovy.
Bevindingen bevestigen de chroniciteit van obesitas en s…
Dec 9, 2024 · 3 shares · 4,954 followersView post →
JT
J.A. Broersma "#terrorist"
@JohnnyBG19 · X
RT @Lily4Lily2: Gewichtstoename slechts 1 jaar na het stoppen met Ozempic/Wegovy.
Bevindingen bevestigen de chroniciteit van obesitas en s…
Dec 9, 2024 · 3 shares · 7,894 followersView post →
L
Lily
@Lily4Lily2 · X
Gewichtstoename slechts 1 jaar na het stoppen met Ozempic/Wegovy.
Bevindingen bevestigen de chroniciteit van obesitas en suggereren dat voortdurende behandeling nodig is om verbeteringen in gewicht en gezondheid te behouden.
https://t.co/DkXGuH3DOF
Dec 9, 2024 · 5 likes · 2 shares · 759 followersView post →
RT @Jikkyleaks: @realjessknight @Bonbonhamilton @Cyndichrishotm1 @Faceles007 @Barbie530652452 @kevinnbass 15-30% withdrew from the trials.…
Dec 7, 2024 · 4 shares · 1,957 followersView post →
YK
You Otter Know
@Barbie530652452 · X
RT @Jikkyleaks: @realjessknight @Bonbonhamilton @Cyndichrishotm1 @Faceles007 @Barbie530652452 @kevinnbass 15-30% withdrew from the trials.…
Dec 7, 2024 · 4 shares · 1,002 followersView post →
IK
Integrityand Karma
@IntegrityandK · X
RT @Jikkyleaks: @realjessknight @Bonbonhamilton @Cyndichrishotm1 @Faceles007 @Barbie530652452 @kevinnbass 15-30% withdrew from the trials.…
Dec 6, 2024 · 4 shares · 1,218 followersView post →
C
Cych
@Cyndichrishotm1 · X
RT @Jikkyleaks: @realjessknight @Bonbonhamilton @Cyndichrishotm1 @Faceles007 @Barbie530652452 @kevinnbass 15-30% withdrew from the trials.…
Dec 6, 2024 · 4 shares · 2,658 followersView post →
J
Jikkyleaks
@Jikkyleaks · X
@realjessknight @Bonbonhamilton @Cyndichrishotm1 @Faceles007 @Barbie530652452 @kevinnbass 15-30% withdrew from the trials.
The weight loss was temporary in those that stayed.
We don't know how many suffered permanent disability as a result of the plasmid contamination.
Even conflicted doctors can't hide the rebound weight problem.
https://t.co/FBrpgo7gI1
Dec 6, 2024 · 12 likes · 4 shares · 116,690 followersView post →
W
wyliepanda
@wyliepanda · X
Perpetual therapeutics are also cash cows for the manufacturers.
In one study, people regained about two-thirds of the weight they lost after stopping Ozempic within one year.
https://t.co/0D09vmkoUt https://t.co/cHnd2TS5pX https://t.co/ktEY8HihVl
@annchitia Аааа, ну короче я пересказываю чё услышал я ж ведомый
Погуглил, исследование есть, если по нему судить, то проблема такая всё-таки имеется, но я так понимаю всё ещё спорный вопрос
https://t.co/Tq7VxMjb0v https://t.co/HBCIi7irVx
Nov 27, 2024 · 2 likes · 11,849 followersView post →
MY
m o c h y
@mochy.bsky.social · Bluesky
"Conclusions: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two-thirds of their prior weight loss, with similar changes in cardiometabolic variables"
pubmed.ncbi.nlm.nih.gov/35441470/
One of the downsides isn't a side effect, but more related to how the drugs work. Using them for weight loss is already being shown to be effective only for as long as you take them, which comes with the implication of a lifelong commitment.
dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/...
Historia real :
(Es de la mamá de un compañero de mi hijo)
Tiene sobrepeso y fue atendida por cuenta de su servicio de salud por un Endocrino
El Endocrino le dice:
Como tiene exceso de peso tiene dos opciones
1. Se inyecta este medicamento.
O
2. Se hace la cirugía https://t.co/iUA7a6H5ZF
Nov 19, 2024 · 114 likes · 34 shares · 168,221 followersView post →
YC
Yuval Cohen
@CEOCorbus · X
@bradloncar And this is the problem: https://t.co/qEhDROcJ6c
بين "التخسيس" ومعالجة "السكّر":
هل الأدوية المطروحة في السوق حاليّاً فعّالة حقّاً!؟
"حلقة مُختارة".
#الاسبتالية
https://t.co/5ITyAjN6Li @YouTube aracılığıyla
Had no idea that these drugs are made from synthetic lizard venom, but kinda makes sense...
"The Dangerous Lies About Ozempic"
https://t.co/TcrKtD8Hao via @YouTube
@markeatsmeat Once Ozempic is stopped, all of the benefits from the medication also stop.
weight and cardiometabolic markers do not stay at levels once the medication is stopped. They slowly return to previous levels if significant lifestyle changes are not made.
So what, is the plan to
@KevinH_PhD @SableSys @DrCarlaPrado We agree more than we disagree Kevin, it's clear. Our perspective, in contrast to your and Sam's and @CatConte_MD was that muscle is something clinicians should be mindful of. It may not be entirely consequential but recidivism is a reality https://t.co/H7qlHIcFNs and that may be
@Tofkism93 في أبحاث الوقت ان بمجرد ما توقف الحقن من غير تغيير لأسلوب حياتك (أكل صحي ورياضة) ها ترجع تتخن تاني أكتر من الأول.
الحلقة دي كويسه لشرح الموضوع اكتر:
https://t.co/wbEuBEmmMn
@JasonJh1319 multiple studies and countless anecdotes about people who gain it back after getting off the glp-1’s.
https://t.co/TYMRCjgwLj
Aug 24, 2024 · 1 like · 6,077 followersView post →
RH
Roots Community Health
@RootsEmpowers · X
Once-Weekly Semaglutide in Adults with Overweight or Obesity:
https://t.co/NnX6bqxFd0
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension
https://t.co/NPkIej9Oy3
#NoMoreCovidDeaths #LongCovid #wastewater #JN1 #H5N1 #coronavirus
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension
Después de la retirada de semaglutida subcutánea los participantes recuperaron dos tercios de su pérdida de peso. https://t.co/orvhnFB4yG
Jul 21, 2024 · 1 like · 3,061 followersView post →
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Ivabradina
@Ricardo37380988 · X
RT @IberianCitizen: Pincharse no enseña a comer, ni vale para siempre, aprovechar el tirón y seguir con los hábitos
Uso de inyecciones para obesidad (ozempic o wegovy)
1. Más del 80% de las personas las suspenden antes de 2 años.?
2. Los investigadores informan que a menudo la interrupción del tratamiento se debe a los efectos secundarios.??
3. Otros análisis han demostrado que, una vez https://t.co/9cYmLDJdsa
Uso de inyecciones para obesidad (ozempic o wegoby)
1. Más del 80% de las personas las suspenden antes de 2 años.?
2. Los investigadores informan que a menudo la interrupción del tratamiento se debe a los efectos secundarios.??
3. Otros análisis han demostrado que, una vez https://t.co/Bobdn2D3HU
2/ Wt recurrence even impacts medical and surgical treatments.
Whether 5-10 years after surgery or in response to med discontinuation, it can be a problem.
Participants experienced a recurrence of ~2/3 of lost wt within a year of med discontinuation. https://t.co/WVL46FRGDF https://t.co/ybrWhNSyfn
@fivehundredpou1 Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - PubMed (https://t.co/ASj5HcnSDy)
so you'd have to be on it forever??
@thecaptain_nemo https://t.co/KrYkCbTC6V
Conclusions: One year after withdrawal regained two-thirds of their prior weight loss
So even after you spend all the time and money messing up your hormones. You gain 70% of it back. And still didn't gain anything meaningful like muslces
Jun 3, 2024 · 2 likes · 2,989 followersView post →
HF
Hector Madariaga, MD FASN
@HecmagsMD · X
@annlbugeja Ongoing treatment with GLP- 1 agonists is required to maintain weight.
https://t.co/cEPDt3yFx5
#ATC2024Philly https://t.co/6FjJE69DYM
Mar 8, 2024 · 2 likes · 11,663 followersView post →
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Ephemeral
@Ephemerallama · X
@annbauerwriter @ifihadastick Not even remaining thin many rebound, small portion even worse than before. Lifelong drug with many side effects many people cant tolerate is not a general society-wide obesity solution. https://t.co/iw0Y4My9J4 https://t.co/1YgO4PB95o
Something fishy here @ConscienHealth. Real world results are not aligning at all with Step 1 Extension RCT. Even when broken down into different weight loss categories; weight regain happens. thoughts @seanwharton https://t.co/FGiADl1T69 https://t.co/gIHatekfBd https://t.co/4UtR2KlwiJ
Jan 25, 2024 · 2 likes · 9,571 followersView post →
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Tom Swiss, HMSH
@tom_swiss · X
@AliceFromQueens @cremieuxrecueil If your idea of "fixable" means "is dependent on a expensive drug for the rest their lives." https://t.co/T5nhlPPfD1
@hellodahlingz One year after stopping 2/3 of the weight was regained and this is just one study. Fa eh la hek Mish kteer mshaja3 ekhdo Sara7a
https://t.co/RZIQfwKaw4
*After calorie counting is discontinued, the dieter will regain more weight than was lost
*Semaglutide discontinuation is same
*Semaglutide causes thyroid cancer, pancreatic burnout, bowel diseases, muscle/bone loss, accelerated aging (face), kidney damage
https://t.co/ZQXcgfCIOq https://t.co/LCS3TWdgYi
@Intimacyenergy @alxoh0lic @danishacarterr Here are a few
https://t.co/AQWo9nAGfi
https://t.co/SUsDaVKU67
https://t.co/xHvkausmEo
https://t.co/6lESN9yIMP
https://t.co/x6GjXPuO7U
Jan 1, 2024 · 5 likes · 1,629 followersView post →
MD
MWR DBM
@mwr_dbm · X
@TiggerBurning @Fresh__pickle @VVHristov Так вот она. Вы вроде человек в теме образованный, а таких элементарных вещей найти не можете и утверждаете, что они не существуют. Более того, подобные же исследования были относительно близкого к семиглютиду агонисту ГЛП-1 лираглютиду. https://t.co/rppUwjEPzS
@aschleighj2022 When they stop taking it, as do the vast majority of patients, the weight comes roaring back--setting people up for weight cycling, which is independently harmful to our health https://t.co/ZzD6V2DMSW
Dec 16, 2023 · 43 likes · 1 share · 45,399 followersView post →
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Walter M.
@Harlegator68 · X
RT @kate_manne: The Ozempic boom is just another case in point. When people stop taking it, as they do in the vast majority of cases due to…
Dec 16, 2023 · 8 shares · 2,065 followersView post →
KM
Kate Manne
@kate_manne · X
The Ozempic boom is just another case in point. When people stop taking it, as they do in the vast majority of cases due to its costs and side effects, the weight comes roaring back. WW keeps profiting on the same old model https://t.co/ZzD6V2DMSW https://t.co/KKWUT2nfzz
Dec 16, 2023 · 50 likes · 8 shares · 45,399 followersView post →
KM
Kate Manne
@kate_manne · X
@OuisieM It comes roaring back https://t.co/ZzD6V2DMSW
Dec 16, 2023 · 3 likes · 45,399 followersView post →
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Heather Clemenceau
@HClemenceau · X
@XHaDOKOH4711 @JV_today_ @stealthygeek Most people seem to gain back weight after discontinuing it, so I'm not sure about beneficial eating habits sticking with them.
https://t.co/Uo35a8Ngm3.
This is the semaglutide rebound data. @BertrandBio and I may disagree, but I think $NVO mgmt must be sounding the alarm here.
https://t.co/b781ggAdGW https://t.co/lFBEYcNY2n
Dec 11, 2023 · 3 likes · 1 share · 9,951 followersView post →
TD
The Doctor
@TennantRob · X
@IonaItalia @TLDWdeasoN Long term, many/most people don’t make the lifestyle changes necessary to sustain the weight loss, otherwise they would not yo-yo.
https://t.co/4RHfP2vknW
Nov 28, 2023 · 1 like · 5,715 followersView post →
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Philip Hinds
@DrPhilipHinds · X
The specific trial referenced in this thread is:
Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. _Diabetes Obes Metab_. 2022;24(8):1553-1564. doi:10.1111/dom.14725
And this is what we see in many of the clinical trials that are now being published. Studies such as this one show that GLP-1 agonists do indeed help tremendously with weight loss. But...
https://t.co/ecwfALmMN2
Nov 11, 2023 · 1 like · 1,858 followersView post →
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Daniele Basta
@dottbasta86 · X
@AurelianoStingi Che poi alla fine, una volta interrotto il trattamento, comporta il riacquisto di 2/3 del peso perso. Può essere efficace ma soltanto all’interno di un cambio delle abitudini alimentari e dello stile di vita (che dovrebbero iniziare proprio nelle scuole)
https://t.co/DgtEzTPXEq
دراسة حديثة بينت عودة ثلثي الوزن المفقود بعد إيقاف استعمال #إبر_التنحيف لمدة سنة و عودة الأمراض المصاحبة للسمنة بعد تحسنها.
الإبر ممتازة و فعالة لكن مفعولها لا يدوم للأبد. المحافظة على نمط حياة سليم هو الأفضل دائما
#الوهاج_خوقير #سمنه #رابطة_المتكممين
https://t.co/axoPxs67nt
RT @SABOURETCardio: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - 2022 - #T2D #Ob…
Oct 29, 2023 · 6 shares · 2,676 followersView post →
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Dr Celestino Gutiérrez González MD
@CelestinoGutirr · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 29, 2023 · 9 shares · 11,287 followersView post →
DM
Dr Celestino Gutiérrez González MD
@CelestinoGutirr · X
RT @SABOURETCardio: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - 2022 - #T2D #Ob…
Oct 29, 2023 · 6 shares · 11,507 followersView post →
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Neil Floch MD
@NeilFlochMD · X
RT @SABOURETCardio: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - 2022 - #T2D #Ob…
Oct 29, 2023 · 6 shares · 130,209 followersView post →
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Neil Floch MD
@NeilFlochMD · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 29, 2023 · 9 shares · 130,120 followersView post →
ZM
Zaher Toumi MD
@ZaherToumi · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 29, 2023 · 9 shares · 7,827 followersView post →
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هاشمية
@LibresMinds · X
RT @Halkhayat: ماذا سيحصل عند ايقاف ادوية السمنة الحديثة مثل اوزيمبك لمدة سنة؟
سيزيد وزنك بنسبة الثلثين من الوزن المفقود
يجب ان يستعد م…
Oct 29, 2023 · 4 shares · 3,552 followersView post →
PB
Polar Bear
@chaiwat_non · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 28, 2023 · 12 shares · 96 followersView post →
AK
Aljosa Kuzmanovski
@Aljoo5 · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 28, 2023 · 12 shares · 105 followersView post →
FG
Felice Gragnano
@FeliceGragnano · X
RT @SABOURETCardio: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - 2022 - #T2D #Ob…
Oct 28, 2023 · 6 shares · 5,520 followersView post →
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SABOURETCardiologist
@SABOURETCardio · X
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - 2022 - #T2D #Obesity and #Metabolism. Change your habits during your period under #GLP1RA https://t.co/jJREHwrpLL
Oct 28, 2023 · 16 likes · 6 shares · 32,733 followersView post →
GR
Ginny Eastwood, RD
@ginny_rd · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 28, 2023 · 9 shares · 715 followersView post →
دا
د. هشام الخياط
@Dralkhayat · X
RT @Halkhayat: ماذا سيحصل عند ايقاف ادوية السمنة الحديثة مثل اوزيمبك لمدة سنة؟
سيزيد وزنك بنسبة الثلثين من الوزن المفقود
يجب ان يستعد م…
Oct 28, 2023 · 4 shares · 158,118 followersView post →
SP
Satish Pattanshetti
@drsatishpattan · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 28, 2023 · 9 shares · 2,404 followersView post →
AR
Amr Ragab
@AmrAliRagab · X
RT @Halkhayat: ماذا سيحصل عند ايقاف ادوية السمنة الحديثة مثل اوزيمبك لمدة سنة؟
سيزيد وزنك بنسبة الثلثين من الوزن المفقود
يجب ان يستعد م…
Oct 28, 2023 · 4 shares · 466 followersView post →
ها
هيثم الخياط
@Halkhayat · X
ماذا سيحصل عند ايقاف ادوية السمنة الحديثة مثل اوزيمبك لمدة سنة؟
سيزيد وزنك بنسبة الثلثين من الوزن المفقود
يجب ان يستعد مريض السمنة لاخذ هذه الادوية طول العمر
جراحات السمنة خيار افضل للسمنة المفرطة خصوصا مع الدراسات عليها لاكثر من ٣٠ سنة https://t.co/NuVCcvy7u9
Oct 28, 2023 · 4 likes · 4 shares · 29,489 followersView post →
CF
Cesar Villa MD FACS
@drdoom22 · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 352 followersView post →
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Ajiman
@Ajiman1 · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 748 followersView post →
EF
Endo Fellow
@endo_fellow · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 33 followersView post →
CM
Christina Huynh Nguyen, MD
@CNTNguyenMD · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 790 followersView post →
CM
Christina Huynh Nguyen, MD
@CNTNguyenMD · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
Oct 27, 2023 · 9 shares · 799 followersView post →
JA
Juan Ignacio Arano
@AranoIgnacio · X
RT @ZaherToumi: One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained…
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 4,771 followersView post →
PH
Patrick Holmes
@drpatrickholmes · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 3,299 followersView post →
ZM
Zaher Toumi MD
@ZaherToumi · X
One year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two-thirds of their prior weight loss, with similar changes in cardiometabolic variables.
#obesity #semaglutide https://t.co/aHC5Gru6ue
Oct 27, 2023 · 30 likes · 9 shares · 7,827 followersView post →
JC
John Conneely
@jbconneely · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 820 followersView post →
DM
Dr Celestino Gutiérrez González MD
@CelestinoGutirr · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 11,507 followersView post →
DJ
Dr. Shashank Joshi
@AskDrShashank · X
RT @NeilFlochMD: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - D…
Oct 27, 2023 · 12 shares · 33,339 followersView post →
NM
Neil Floch MD
@NeilFlochMD · X
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - Diabetes, Obesity and Metabolism - Wiley Online Library https://t.co/hg3AXWushU
Oct 27, 2023 · 40 likes · 12 shares · 130,209 followersView post →
DW
Dr Murphy WeightLoss
@TakeWeightOffMD · X
RT @MichaelAlbertMD: I challenge any employer or telehealth practice to demonstrate treatment withdrawal is not harmful! Show me the data b…
Oct 27, 2023 · 1 share · 6,784 followersView post →
MM
Michael Albert, MD
@MichaelAlbertMD · X
I challenge any employer or telehealth practice to demonstrate treatment withdrawal is not harmful! Show me the data because the existing data suggests you are directly CAUSING HARM.
Study: https://t.co/eMFDsCXOp3 https://t.co/OGCWvIEk1g
Oct 27, 2023 · 15 likes · 1 share · 15,910 followersView post →
SH
Stuart Phillips (he/him)
@mackinprof · X
@RedPillMD @MichaelAlbertMD @karrie_sequeira This may be a better paper to make my point: https://t.co/PqsdxrD5os
Don't get me wrong, the meds are great, but sustained weight loss - after withdrawal from the drug - is still a tough proposition!
@MichaelAlbertMD Can we all also agree that the recidivism of weight regain if you stop taking the meds is not inconsequential? https://t.co/PqsdxrD5os
Oct 25, 2023 · 2 likes · 58,352 followersView post →
@TheStalwart They will lobby for it to be scrutinized on long term effects and limit its use to shorter time frames.
Studies showed patients regained 2/3rds of weight lost after discontinuing the drug.
Snackmakers can bank on most people not adjusting lifestyle
https://t.co/Y9yJSl3Xfe
@moistowelette27 @BradMossEsq Studies show that average weight regain is about 2/3 of what was lost. I.e., if you lost 15 pounds taking Ozempic, you can be expected to regain 10 pounds 1 year after discontinuing treatment.
On average, you dont end up heavier than when you started.
https://t.co/wTT1KIS2SL
Ahora, los efectos adversos:
https://t.co/hnbvDNwQwb
Recuperación de peso y efectos cardiometabólicos tras la retirada de semaglutida: extensión del ensayo STEP 1
Un año después de la retirada de semaglutida 2,4 mg una vez a la semana por vía subcutánea y de la intervención sobre
Reganancia de peso al suspender medicamentos para disminucion de peso. El trabajo mental y conductual es muy arduo para evitar este proceso.
https://t.co/w5x7tclFu5
Ozempic/Wegovy are all over the news & a lot of misconceptions
Here’s a trial on what happens when treatment is stopped
Link: https://t.co/OAnAscAvFP https://t.co/4ylTq0fLH5
@CamilaJcruz @MWeintraubMD Wilding, J. P., Batterham, R. L., Davies, M., Van Gaal, L. F., Kandler, K., Konakli, K., ... & STEP 1 Study Group. (2022). Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension. Diabetes, Obesity and Metabolism, 24(8), 1553-1564.
RT @AniaJastreboff: An important study✨demonstrating that physiology fights back resulting in weight regain when treatment is discontinued…
Jun 26, 2023 · 62 shares · 290 followersView post →
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CharlesCMann
@CharlesCMann · X
@Royal_Arse Re-gain is a big issue. But it's early days with these drugs yet, and this is something researchers are working on understanding. https://t.co/XL8qNoTbGr
Jun 26, 2023 · 2 likes · 17,299 followersView post →
SG
Sandy George
@SandyGeorge79 · X
@drsaltzman @merryberry9 @Torontomom22 @blackqueeriroh @drmuhlheim It’s termed “Ozempic rebound”, you can Google it, here’s one article:
https://t.co/fyAQgnj9o8
RT @FarmaMadridAP: (Diabetes Obes Metab) Un año después de la retirada de semaglutida 2,4 mg SC y la intervención en el estilo de vida, 2/…
Jun 15, 2023 · 6 shares · 124 followersView post →
OH
Omid Hakami Hakami
@Omidhakami · X
RT @FarmaMadridAP: (Diabetes Obes Metab) Un año después de la retirada de semaglutida 2,4 mg SC y la intervención en el estilo de vida, 2/…
Jun 15, 2023 · 6 shares · 505 followersView post →
VJ
Victor Juárez
@victormjt · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 971 followersView post →
SS
Sociedad SEEN
@sociedadSEEN · X
Artículo comentado por el Dr. José Ignacio Martínez Montoro ▶ “Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension“
En el #blog de @ObesitySeen
Jun 15, 2023 · 2 likes · 3 shares · 17,123 followersView post →
TF
Telaraña Farmacéutica
@telarfarma · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 1,442 followersView post →
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marigvaldivieso
@marigvaldivieso · X
RT @FarmaMadridAP: (Diabetes Obes Metab) Un año después de la retirada de semaglutida 2,4 mg SC y la intervención en el estilo de vida, 2/…
Jun 15, 2023 · 6 shares · 3,890 followersView post →
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NadaQueAlegar
@NadaQueAlegar · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 338 followersView post →
ES
Estrella Sancho
@ESTRELLASANCHO · X
RT @FarmaMadridAP: (Diabetes Obes Metab) Un año después de la retirada de semaglutida 2,4 mg SC y la intervención en el estilo de vida, 2/…
Jun 15, 2023 · 6 shares · 1,199 followersView post →
FA
Farmacia Madrid AP
@FarmaMadridAP · X
(Diabetes Obes Metab) Un año después de la retirada de semaglutida 2,4 mg SC y la intervención en el estilo de vida, 2/3 de los pacientes recuperaron su pérdida de peso previa. Extensión del ensayo STEP 1 https://t.co/c9xivKfrQ3
Jun 15, 2023 · 4 likes · 6 shares · 8,347 followersView post →
MP
Miguel Ibarra MD, MPH, PhD
@Miggs_Ibarra · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 628 followersView post →
MV
Marimar Velazquez
@mar_marvelal · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 188 followersView post →
EH
Erika Hernandez
@erhervi · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 955 followersView post →
CA
Clara Arenós
@aremoncl · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 15, 2023 · 39 shares · 200 followersView post →
JG
Jose Matute Gimenez
@JoseMatuteGimen · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 14, 2023 · 39 shares · 1,020 followersView post →
LM
Leonardo Soto Muñoz
@LeonardoSotoMu · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 14, 2023 · 39 shares · 8,457 followersView post →
JA
José Antonio
@J_Antonio0619 · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 14, 2023 · 39 shares · 195 followersView post →
HP
Hernán Perea
@hernoperea · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
Jun 14, 2023 · 39 shares · 223 followersView post →
LC
Lorena Ajila Chamaidan
@ajila_lorena · X
RT @pzjarana: Tratamiento con 2,4 mg de semaglutida durante 68 semanas - Bajada de unos 18 kg de media
Retiran la medicación y en 52 seman…
@DobryJane @MedscapeEndo In case you have an interest in facts, all the weight does not "come back plus more." The fact is that people only regain 2/3 of the weight they lost a year after they stop taking it. Obesity is a chronic condition. Here is the study:
https://t.co/p0hIeDLuGc https://t.co/aUrJ59saNo
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension https://t.co/QRU6uqUkRo
Jan 16, 2023 · 4 likes · 1 share · 385 followersView post →
RR
Rafael Radaeli
@rfradaeli · X
RT @EndocrinoLaPaz:
Jan 16, 2023 · 2 shares · 382 followersView post →
S
SANCYD
@SANCYDnutricion · X
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - Diabetes, Obesity and Metabolism - Wiley Online Library https://t.co/PnPaAMAdZu
Jan 16, 2023 · 1 like · 3,013 followersView post →
MR
María Recarte Rico
@recarterico_me · X
RT @EndocrinoLaPaz:
Jan 15, 2023 · 2 shares · 458 followersView post →
E
EndocrinoLaPaz
@EndocrinoLaPaz · X
Jan 15, 2023 · 6 likes · 2 shares · 620 followersView post →
JD
Joe Devon
@joedevon · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
Dec 22, 2022 · 32 shares · 6,025 followersView post →
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tudoctorfavorito
@doctorfavorito · X
Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553-1564. doi:10.1111/dom.14725
Pónganle ganas al google scholar, aqui no es primaria. https://t.co/SVO1EpWSDB
Dec 11, 2022 · 1 like · 6,609 followersView post →
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JORGE FERNANDEZ
@drjorfer · X
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - 2022 - Diabetes, Obesity and Metabolism - Wiley Online Library✅✅✅ https://t.co/W0WSbLKRwj
Open Access UCL Research: Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension https://t.co/ytl5tRuTVD
Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Wilding - - Diabetes, Obesity and Metabolism - Wiley Online Library
Obesidade é uma doença crônica que necessita tratamento contínuo. https://t.co/qhyQeaI6JC
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 783 followersView post →
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Joe Zucchi, PA-C, CPT
@JPZfitness · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 245 followersView post →
DJ
Dr. Shashank Joshi
@AskDrShashank · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 32,532 followersView post →
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Prof Kamlesh Khunti
@kamleshkhunti · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 24,425 followersView post →
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Costas Tsakirides
@tsakirides · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 1,472 followersView post →
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Dr Tom Butler
@drtom_butler · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 3,408 followersView post →
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vmc
@vmckamc · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 12, 2022 · 32 shares · 293 followersView post →
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FabiolaRDMS
@FabiolaRDMS · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 78 followersView post →
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Jean-Claude Fox
@JeanClaudeFox2 · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 322 followersView post →
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Daniel Lam
@dna_lam · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 197 followersView post →
DC
Daniel Brockmann Ernährungs Coaching
@DanielsFuNcoach · X
@sguyenet
A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatment. Some interesting things to chew on in this paper.
h/t @kamleshkhunti
https://t.co/uwV4g9jZig https://t.co/AX0sqlcm3u
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 14,608 followersView post →
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Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 6,717 followersView post →
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Alberto Andrade
@Springandashura · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 224 followersView post →
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David Breen
@sanpellebreeno · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 356 followersView post →
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Hayle George C Scott
@haylesatan · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 3,271 followersView post →
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Robb!e
@RobbieG_PhD · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 180 followersView post →
HE
Hormone Equilibrium
@HormoneEquilib · X
RT @sguyenet: A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatm…
May 11, 2022 · 32 shares · 1,887 followersView post →
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Stephan J. Guyenet
@sguyenet · X
A recent study examines what happens when the new weight loss drug semaglutide (Wegovy) is withdrawn after 68 weeks of treatment. Some interesting things to chew on in this paper.
h/t @kamleshkhunti
https://t.co/eCaOObyIk6
May 11, 2022 · 136 likes · 32 shares · 48,844 followersView post →
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Doctor Mime
@DoctorMime · X
SEMAGLUTIDA Y PESO: La interrupción de la semaglutida está asociada con el aumento de peso y puede estar asociada con la reversión de los beneficios cardiovasculares
https://t.co/80OG6LbSZ7
Guarding the Gift of Giving in: Kidney News Volume 18 Issue 3 (2026)
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doi: 10.1111/dom.14725. PubMed. Wilding JPH , ; STEP 1 Study Group . Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 ...
Making Obesity Care Affordable: Patient Views on Deprescribing ...
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... 10.1111/dom.14725. 4. Cengiz A, Wu CC, Lawley SD. Alternative dosing regimens of GLP-1 receptor agonists may reduce costs and maintain weight loss efficacy ...
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