May 2022 PMID 35521043

Frontiers in Lichen Planopilaris and Frontal Fibrosing Alopecia Research: Pathobiology Progress and Translational Horizons.

Maryanne Makredes Senna, Erik Peterson, Ivan Jozic, Jérémy Chéret, Ralf Paus

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Mentions

5
Peak: 3 in May 2022
across 2 sources since May 2022

Extended reach

9,887
potential audience

Total likes

142

Video views

8,423

Mentions per month

May 2022 – Mar 2025

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone is supportive and mildly engaged, with references to foundational concepts like immune responses involving CD8 T cells, indicating a recognition of the research's significance. Phrases like 'review on possible disease mechanisms' and hashtags such as #openaccess reflect a desire to share and disseminate important scientific findings, while the tone remains cautious and exploratory rather than highly enthusiastic or critical.

AgreementModerate agreement

Most discussions acknowledge the importance of understanding the mechanisms behind LPP and FFA, showing general support.

InterestModerate interest

Participants show curiosity about the research, as evidenced by comments highlighting the relevance and potential treatments.

EngagementNeutral engagement

The exchanges are somewhat superficial, with some posts sharing summaries or expressing interest without deep analysis.

ImpactModerate impact

The discussions suggest the research has a meaningful impact on advancing knowledge in alopecia, with references to disease mechanisms and future therapies.

Abstract in brief

  • Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are types of scarring hair loss caused by an immune attack on hair follicle stem cells, leading to follicle damage, fibrosis, and loss of hair regeneration.
  • Recent research suggests that both conditions may share a common initial immune-related pathway, involving CD8 T cells, but then diverge into different clinical types, possibly influenced by macrophages and other factors.
  • Future treatment strategies might focus on protecting hair follicle stem cells with topical therapies that inhibit immune responses, such as tacrolimus and other agents targeting PPAR and CB1 receptors.]

Top posts

Most liked on X and Bluesky
Kevin McElwee
@ResearchHair · X

A review on the possible disease mechanisms behind the development of scarring alopecias - Lichen Planopilaris and Frontal Fibrosing Alopecia. From @hairwithdrmare and colleagues. #openaccess https://t.co/5wapVyTeRf

May 10, 2022 · 3 likes · 2 shares · 883 followers View post →
MARTA • trichologist/dermatology nurse
@clinihair · X

RT @ResearchHair: A review on the possible disease mechanisms behind the development of scarring alopecias - Lichen Planopilaris and Fronta…

May 10, 2022 · 2 shares · 310 followers View post →

All mentions

StephTs
@STurcios_Sa · X

RT @ResearchHair: A review on the possible disease mechanisms behind the development of scarring alopecias - Lichen Planopilaris and Fronta…

May 10, 2022 · 2 shares · 260 followers View post →
MARTA • trichologist/dermatology nurse
@clinihair · X

RT @ResearchHair: A review on the possible disease mechanisms behind the development of scarring alopecias - Lichen Planopilaris and Fronta…

May 10, 2022 · 2 shares · 310 followers View post →
Kevin McElwee
@ResearchHair · X

A review on the possible disease mechanisms behind the development of scarring alopecias - Lichen Planopilaris and Frontal Fibrosing Alopecia. From @hairwithdrmare and colleagues. #openaccess https://t.co/5wapVyTeRf

May 10, 2022 · 3 likes · 2 shares · 883 followers View post →