Front Pediatr April 2022 PMID 35529328

Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childhood: Systematic Review and Meta-Analysis.

Mengyang He, Xiangling Deng, Xuan Wang, Yuxiang Wan, Jinchang Huang, Zhixin Zhang, Wenquan Niu

Mentions

7
Peak: 2 in May 2022
across 3 sources since May 2022

Extended reach

590,154
potential audience

Total likes

5,849

Video views

584,015

Mentions per month

May 2022 – Sep 2024

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions reflect a generally cautious attitude towards the publication, with users highlighting key points such as the absence of a definitive link between growth hormone and cancer, while also emphasizing that some data suggest increased risk of second tumors. The tone varies from supportive to skeptical, and the language used by posters indicates an analytical approach, considering both the study's findings and its limitations.

AgreementModerate agreement

Most posts express support or skepticism towards the publication's conclusions, with some emphasizing that no definitive link between growth hormone and cancer has been established, indicating a leaning towards agreement with the study's cautious findings

InterestHigh interest

Posts show high curiosity, especially around the safety concerns and implications of growth hormone therapy, demonstrating active engagement with the topic.

EngagementModerate engagement

Discussions include references to the study's methods and interpretation, with some users debating the validity of the findings and the potential risks involved.

ImpactModerate impact

While the posts enhance awareness about the research, the overall influence on clinical practice or policy appears moderate, as critics highlight the need for further studies.

Abstract in brief

  • This study reviewed data from 24 articles to examine whether recombinant human growth hormone (rhGH) therapy in children and adolescents is linked to increased risk of death, cancer, or second tumors, finding that overall, rhGH does not significantly increase most of these risks.
  • However, the analysis did find a statistically significant increased risk of developing a second tumor in children who received rhGH therapy, suggesting that while it may not raise general mortality or initial cancer risk, it could be associated with tumor recurrence.
  • The researchers emphasize that more future studies are needed to confirm these findings and determine the safest and most effective dosage of rhGH treatment for young patients.]

Top posts

Most liked on X and Bluesky
RaulZavala(Raikunza)
@rzavala797 · X

@topacero @ratagoticatetas Ni si quiera se ha establecido vínculo con el desarrollo de tumores en aquellos pacientes tratados con hormona del crecimiento. Tal vez haya riesgo, pero decir abiertamente que la hormona del crecimiento causa cáncer es simplemente una mentira https://t.co/u1bhewSrWQ

Jun 25, 2024 · 9 likes · 124 followers View post →
Frontiers - Pediatrics
@FrontPediatrics · X

New Research: Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childhood: Systematic Review and Meta-Analysis: Objectives The safety of recombinant human growth hormone (rhGH) treatment in… https://t.co/XAmYno3aYL #Pediatrics

May 27, 2022 · 2 likes · 1 share · 4,035 followers View post →

All mentions

RaulZavala(Raikunza)
@rzavala797 · X

@topacero @ratagoticatetas Ni si quiera se ha establecido vínculo con el desarrollo de tumores en aquellos pacientes tratados con hormona del crecimiento. Tal vez haya riesgo, pero decir abiertamente que la hormona del crecimiento causa cáncer es simplemente una mentira https://t.co/u1bhewSrWQ

Jun 25, 2024 · 9 likes · 124 followers View post →
Marcio Fossari
@marciofossari · X

RT @FrontPediatrics: New Research: Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childh…

May 27, 2022 · 1 share · 1,957 followers View post →
Frontiers - Pediatrics
@FrontPediatrics · X

New Research: Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childhood: Systematic Review and Meta-Analysis: Objectives The safety of recombinant human growth hormone (rhGH) treatment in… https://t.co/XAmYno3aYL #Pediatrics

May 27, 2022 · 2 likes · 1 share · 4,035 followers View post →
How to Talk to your Child About Growth Hormone Deficiency
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Risks and Benefits From Growth Hormone Therapy
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