J Am Heart Assoc May 2022 PMID 35574962

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS.

Charlene E Goh, Bruno Bohn, Clarisse Marotz, Rebecca Molinsky, Sumith Roy, Bruce J Paster, Ching-Yuan Chen, Michael Rosenbaum, Melana Yuzefpolskaya, Paolo C Colombo, Moïse Desvarieux, Panos N Papapanou, David R Jacobs, Rob Knight, Ryan T Demmer

Mentions

7
Peak: 3 in May 2022
across 2 sources since May 2022

Extended reach

72,493
potential audience

Total likes

1,849

Video views

25,647

Mentions per month

May 2022 – Jan 2026

Where it's discussed

  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

Many discussions highlight key findings, such as the importance of nitrite generation in health, using terms like 'provides support' and 'important role,' which reflect respect and curiosity. The tone indicates a mix of agreement and curiosity, especially with references to future studies and health implications, demonstrating meaningful engagement without extensive critique.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, emphasizing the role of nitrite in cardiometabolic health and supporting its findings.

InterestHigh interest

The topic appeals strongly to those interested in microbiome research and health, indicated by enthusiastic phrases and tagging relevant figures.

EngagementModerate engagement

Several posts reference the detailed content, such as the role of nitrite depletion and future studies, showing thoughtful engagement.

ImpactModerate impact

Discussions suggest the findings could influence future research and health strategies, recognizing the study’s potential broader importance.

Abstract in brief

  • The study investigates how the presence of certain oral bacteria that produce nitrite might influence cardiometabolic health in adults, suggesting a link between oral microbiota and reduced health risks.
  • By analyzing dental plaque samples from 764 participants, researchers measured gene abundances related to nitrogen metabolism and created summary scores to evaluate their impact on cardiometabolic profiles.
  • Results indicated that a higher ratio of genes producing nitric oxide (NO) compared to those connected to ammonia (NH) was associated with a lower risk of cardiometabolic issues, while higher NH levels suggested greater nitrite depletion linked to increased health risks.

Top posts

Most liked on X and Bluesky
Mike Lustgarten, PhD
@mike_lustgarten · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/Twp4ZJsolv

Jul 5, 2022 · 4 likes · 1 share · 9,831 followers View post →
JAHA
@JAHA_AHA · X

Nitrite depletion plays an important role in the enterosalivary pathway and provides support for future studies examining the interplay of nitrite generation and depletion and cardiometabolic health. @RebeccaMolinsky #AHAJournals https://t.co/zrLWWCbiWs https://t.co/0cbDQxiveW

May 24, 2022 · 31,675 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/WXomjiy8U1

May 16, 2022 · 3,682 followers View post →
Symbiosis papers
@Symbiosispapers · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/ndyvuy1oMg

May 17, 2022 · 1,101 followers View post →

All mentions

Diana
@PharmphoodTM · X

RT @mike_lustgarten: Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https:…

Jul 5, 2022 · 1 share · 553 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/Twp4ZJsolv

Jul 5, 2022 · 4 likes · 1 share · 9,831 followers View post →
JAHA
@JAHA_AHA · X

Nitrite depletion plays an important role in the enterosalivary pathway and provides support for future studies examining the interplay of nitrite generation and depletion and cardiometabolic health. @RebeccaMolinsky #AHAJournals https://t.co/zrLWWCbiWs https://t.co/0cbDQxiveW

May 24, 2022 · 31,675 followers View post →
Symbiosis papers
@Symbiosispapers · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/ndyvuy1oMg

May 17, 2022 · 1,101 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS https://t.co/WXomjiy8U1

May 16, 2022 · 3,682 followers View post →