May 2022 PMID 35619143

Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration.

Samaneh Dehghan, Reza Mirshahi, Alireza Shoae-Hassani, Masood Naseripour

Mentions

7
Peak: 3 in Jul 2025
across 3 sources since Jun 2022

Extended reach

359,394
potential audience

Total likes

6,159

Video views

359,205

Mentions per month

Jun 2022 – Aug 2025

Where it's discussed

  • YouTube5 videos
  • X / Twitter1 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions highlight promising results from new trials, such as Eyestem’s phase 1 trial showing positive outcomes, and reviews of generating iPSC-based therapies for dry AMD, using phrases like 'revolutionary' and 'hopeful developments' which indicate a generally optimistic tone that underscores the potential impact of these advancements.

AgreementModerate agreement

Most discussions reflect optimistic support for the advancements and potential of stem cell therapies for AMD, indicating agreement with the publication's significance.

InterestModerate interest

Comments show moderate curiosity, with mentions of trial results and new protocols pointing to a general interest in the scientific progress.

EngagementModerate engagement

Participants discuss specific developments like the Eyestem trial results and protocol reviews, implying some deep engagement.

ImpactModerate impact

The emphasis on positive trial outcomes and the development of new therapeutic approaches suggests recognition of a meaningful impact on future AMD treatments.

Abstract in brief

  • Human-induced pluripotent stem cells (iPSCs) offer a promising new approach for treating age-related macular degeneration (AMD) by generating retinal pigment epithelium (RPE) cells, which are crucial for helping restore retinal function.
  • Current treatments are effective for wet AMD but lack options for dry AMD, making stem cell therapies a potential breakthrough especially since iPSCs can be created without ethical concerns associated with embryonic stem cells.
  • The article reviews how iPSC-derived RPE cells are produced and discusses recent advancements in using these cells for regenerative therapy aimed at restoring vision in AMD patients.

Top posts

Most liked on X and Bluesky
EyeVidence
@EyeVidence · X

A review that discusses protocols for the generation of induced pluripotent #StemCell and recent developments regarding therapies for dry AMD. https://t.co/ke7fH6vghX

Jun 10, 2022 · 1 like · 190 followers View post →
ophthoscope.bsky.social
@ophthoscope.bsky.social · Bluesky

Eyestem releases positive results from phase 1 trial in patients with geographic atrophy Eyecyte-RPE is a suspension of human induced Pluripotent Stem Cells derived retinal pigment epithelial cells. www.ophthalmologytimes.com/view/eyestem...

Apr 14, 2025 View post →

All mentions

ophthoscope.bsky.social
@ophthoscope.bsky.social · Bluesky

Eyestem releases positive results from phase 1 trial in patients with geographic atrophy Eyecyte-RPE is a suspension of human induced Pluripotent Stem Cells derived retinal pigment epithelial cells. www.ophthalmologytimes.com/view/eyestem...

Apr 14, 2025 View post →
EyeVidence
@EyeVidence · X

A review that discusses protocols for the generation of induced pluripotent #StemCell and recent developments regarding therapies for dry AMD. https://t.co/ke7fH6vghX

Jun 10, 2022 · 1 like · 190 followers View post →