Mitochondrial Dysfunction in Cardiovascular Diseases: Potential Targets for Treatment.

Abstract in brief

• Mitochondrial dysfunction plays a key role in the development of cardiovascular diseases (CVDs), partly because mitochondria produce energy but also generate harmful reactive oxygen species (ROS) that can damage cells.
• The body can protect against mitochondrial damage through processes that maintain mitochondrial balance, and recent research has focused on targeting mitochondria to treat CVDs.
• Studies show that certain drugs, like ACE inhibitors and angiotensin receptor blockers, can protect mitochondria and have potential as therapies for preventing or treating heart-related diseases.]