July 2022 PMID 35648414

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review.

Behnood Bikdeli, Farbod Zahedi Tajrishi, Parham Sadeghipour, Azita H Talasaz, John Fanikos, Giuseppe Lippi, Deborah M Siegal, John W Eikelboom, Manuel Monreal, David Jimenez, Jean M Connors, Walter Ageno, Geoffrey D Barnes, Gregory Piazza, Dominick J Angiolillo

Mentions

115
Peak: 60 in Jun 2022
across 3 sources since Jun 2022

Extended reach

523,533
potential audience

Total likes

294

Video views

1,278

Mentions per month

Jun 2022 – Nov 2025

Where it's discussed

  • X / Twitter112 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

Several discussions highlight agreement with the review's findings, mentioning the importance of dose adjustment for atrial fibrillation and cautioning against its use for VTE treatment; for example, users discuss the relevance of low-intensity treatment and references to specific trials, using language that indicates they see this review as significant for future clinical decisions.

AgreementStrong agreement

Most discussions emphasize the importance of dose adjustment strategies and agree with the review's conclusions, reflecting consensus in the community.

InterestHigh interest

The discussions display a high level of attention to the topic, with numerous posts discussing specifics about dose-reduction methods and their implications.

EngagementModerate engagement

Many users reference the article directly, quoting or summarizing key points, indicating active engagement but not deep original analysis.

ImpactModerate impact

The widespread sharing and validation suggest the review influences practices and perceptions around anticoagulant dosing, though some notes about ongoing research temper the perceived immediate impact.

Abstract in brief

  • Dose-reduced DOACs are used for full-intensity treatment like stroke prevention in atrial fibrillation or for lower-intensity, extended treatments such as venous thromboembolism (VTE).
  • In clinical trials, dose-adjusted DOACs showed similar safety and effectiveness to full doses in stroke prevention for AF, but they are less studied for acute VTE treatment.
  • Real-world use of dose-reduced DOACs varies and is sometimes inconsistent with clinical trial data, with different regulations across regions affecting dose adjustment criteria.

Top posts

Most liked on X and Bluesky
manuel monreal
@mmonrealriete · X

Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review https://t.co/Dm1xmIbP3W

Jul 1, 2022 · 49 likes · 20 shares · 2,097 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/A7ZuahGmwH

Jul 22, 2022 · 34 likes · 14 shares · 48,131 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/TK9BhPE5dE

Aug 9, 2022 · 31 likes · 20 shares · 48,131 followers View post →
manuel monreal
@mmonrealriete · X

Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for primary or secondary VTE prevention Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review https://t.co/Dm1xmIbP3W

Jun 3, 2022 · 31 likes · 16 shares · 2,097 followers View post →
Francesc Formiga
@FormigaFrancesc · X

BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMACardio @JAMANetwork @fikkumamoto @vic_pallares @Medtorek @chemachir @QuirosLopezRaul @mendez_bailon @drmiguelmarcos @roca_ferran @DrMarthaGulati @GiuseppeGalati_

Jun 2, 2022 · 28 likes · 12 shares · 1,970 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/rCkTvaNG2h

Jun 2, 2022 · 22 likes · 11 shares · 48,131 followers View post →

All mentions

DeLasSalas
@DrDeLasSalasGER · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/CdeLOZFq2Q vía @JAMACardio part of @JAMANetwork

Aug 9, 2022 · 696 followers View post →
koichi
@koichi_pt · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 4,444 followers View post →
Cher ባንቄ
@tsebank · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 48 followers View post →
Azita Talasaz, PharmD
@AzitaTalasaz · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 273 followers View post →
David Jiménez
@DJC6998 · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 1,421 followers View post →
Dr. Sudip Kandar
@DrKsudip · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 6 followers View post →
Giulio Francesco Romiti
@GiulioFRomiti · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 190 followers View post →
Liverpool Centre for Cardiovascular Science
@LiverpoolCCS · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 1,473 followers View post →
Dr.med. Bernd Kynast
@DrKynast · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 3,008 followers View post →
Erin T. Pharm.D.,BSPS,BCACP
@eltpharmd · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 1,474 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 39,891 followers View post →
Michael Klinkhammer
@klinki_hh · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Aug 9, 2022 · 20 shares · 679 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/TK9BhPE5dE

Aug 9, 2022 · 31 likes · 20 shares · 48,131 followers View post →
Ascen H
@ascenneumo · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 54 followers View post →
David Jiménez
@DJC6998 · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 1,421 followers View post →
David Jiménez
@DJC6998 · X

RT @bbikdeli: Our @JAMACardio review of dose-⬇️DOACs #apixaban #rivaroxaban #edoxaban #dabigatran 1. Low-intensity is ≠ dose-adjusted

Jul 22, 2022 · 13 shares · 1,421 followers View post →
Azita Talasaz, PharmD
@AzitaTalasaz · X

RT @bbikdeli: Our @JAMACardio review of dose-⬇️DOACs #apixaban #rivaroxaban #edoxaban #dabigatran 1. Low-intensity is ≠ dose-adjusted

Jul 22, 2022 · 13 shares · 273 followers View post →
Manan Pareek, MD, MSc, PhD, FAHA, FESC
@MananPareekMD · X

RT @bbikdeli: Our @JAMACardio review of dose-⬇️DOACs #apixaban #rivaroxaban #edoxaban #dabigatran 1. Low-intensity is ≠ dose-adjusted

Jul 22, 2022 · 13 shares · 953 followers View post →
Behnood Bikdeli
@bbikdeli · X

Our @JAMACardio review of dose-⬇️DOACs #apixaban #rivaroxaban #edoxaban #dabigatran 1. Low-intensity is ≠ dose-adjusted

Jul 22, 2022 · 16 likes · 13 shares · 1,267 followers View post →
Dr Haixu Yu, MD, PhD
@JohnsonyuMdphd · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 55 followers View post →
Liverpool Centre for Cardiovascular Science
@LiverpoolCCS · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 1,473 followers View post →
Ahmed rashed
@Ahmed_saegh · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 117 followers View post →
Awatif Hafiz , PharmD , BCCP
@awatifhafiz · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 414 followers View post →
Janet B. Campbell RN, BSN, CACP
@janbcam · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jul 22, 2022 · 14 shares · 71 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/A7ZuahGmwH

Jul 22, 2022 · 34 likes · 14 shares · 48,131 followers View post →
Ana Blanco Hidalgo
@anablancoha · X

RT @CordobaETV: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/1engz2WxO4 vía @JAMACardio p…

Jul 19, 2022 · 3 shares · 1,492 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @SABOURETCardio: Efficacy and Safety Considerations With Dose-Reduced #DOAC look at the conclusion https://t.co/bAuFq0DqWu

Jul 2, 2022 · 2 shares · 3,379 followers View post →
EOLO MORANDI JR.
@eolojr · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 544 followers View post →
SABOURETCardiologist
@SABOURETCardio · X

Efficacy and Safety Considerations With Dose-Reduced #DOAC look at the conclusion https://t.co/bAuFq0DqWu

Jul 2, 2022 · 11 likes · 2 shares · 31,395 followers View post →
Sintayehu Abebe
@sinta_gf · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 450 followers View post →
Ethiopian Society of Cardiac Professionals-ESCP
@SCPEthiopia · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 414 followers View post →
RIM
@Ricardoscientia · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 913 followers View post →
Cristian Añez. FACS
@cristian_anez · X

RT @CordobaETV: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/1engz2WxO4 vía @JAMACardio p…

Jul 2, 2022 · 3 shares · 268 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 12,250 followers View post →
Luis Jara-Palomares
@luistrombo · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 604 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 2,716 followers View post →
Álvaro Dubois-Silva
@AlvaroDibua · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 268 followers View post →
José Mª Gª Quintana
@jose_g_quintana · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 2, 2022 · 20 shares · 850 followers View post →
Majed Alzahrani
@Mmsalzahrani · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 399 followers View post →
Gabriel Puche, MD/PhD
@gabi_puchepalao · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 8,374 followers View post →
Azita Talasaz, PharmD
@AzitaTalasaz · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 273 followers View post →
Giuseppe Rescigno
@GiuRescigno · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 48 followers View post →
Behnood Bikdeli
@bbikdeli · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 1,267 followers View post →
David Jiménez
@DJC6998 · X

RT @CordobaETV: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/1engz2WxO4 vía @JAMACardio p…

Jul 1, 2022 · 3 shares · 1,421 followers View post →
CordobaETV
@CordobaETV · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/1engz2WxO4 vía @JAMACardio part of @JAMANetwork

Jul 1, 2022 · 6 likes · 3 shares · 484 followers View post →
Awatif Hafiz , PharmD , BCCP
@awatifhafiz · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 414 followers View post →
Manu Morales Sánchez
@Manugrillo2 · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 2,135 followers View post →
Manu Morales Sánchez
@Manugrillo2 · X

Dose adjustment and low-intensity treatment are 2 different forms of dose-reduced #DOACs. Dose adjustment is mostly relevant for #AF and should be done based on the approved criteria. https://t.co/CRerDt7x4V

Jul 1, 2022 · 2,135 followers View post →
trombo.info
@tromboinfo · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 1,592 followers View post →
ASEMEVE
@asemeve · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 480 followers View post →
César Andrés Mafla H
@cmaflah · X

RT @mmonrealriete: Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy a…

Jul 1, 2022 · 20 shares · 183 followers View post →
manuel monreal
@mmonrealriete · X

Low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review https://t.co/Dm1xmIbP3W

Jul 1, 2022 · 49 likes · 20 shares · 2,097 followers View post →
Manu Morales Sánchez
@Manugrillo2 · X

RT @TaniaAhuja:

Jun 11, 2022 · 3 shares · 2,135 followers View post →
ELVIRA LARA
@ElviraLaraCuest · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 6, 2022 · 16 shares · 101 followers View post →
Dra. María Alejandra Torres Viera
@dramatorresvi · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 6, 2022 · 16 shares · 529 followers View post →
Liverpool Health Partners
@LivHPartners · X

RT @LiverpoolCCS: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | JAMA…

Jun 6, 2022 · 2 shares · 3,691 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/CvINcGTDXS a través de @JAMACardio part of @JAMANetwork

Jun 5, 2022 · 2 likes · 620 followers View post →
BEATCME
@CmeBeat · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 5, 2022 · 16 shares · 54 followers View post →
Satoru Mitsuboshi
@3stars67664378 · X

RT @pinacol: 【総説】減量したDOACの有効性と安全性 #ペ読 https://t.co/1JuR2L4qS0

Jun 5, 2022 · 1 share · 1,828 followers View post →
Behnood Bikdeli
@bbikdeli · X

@gunnar_heine Thx so much! Great comment. Many❓about pts w advanced renal dysfunction & ESRD. #RENAF_AF❌, #VALKYRIE was interesting but not large enough. Regulatory bodies made recs based on not-so-strong data...My hope is more RCTs in the next Ys. Some in Appendix. https://t.co/LVhyAwUhZK

Jun 4, 2022 · 1,267 followers View post →
Manu Morales Sánchez
@Manugrillo2 · X

RT @LiverpoolCCS: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | JAMA…

Jun 4, 2022 · 2 shares · 2,135 followers View post →
Luciano López
@lucedulop · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 4, 2022 · 16 shares · 265 followers View post →
Liverpool Centre for Cardiovascular Science
@LiverpoolCCS · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | JAMA Cardiology | JAMA Network @LHCHFT @LivHPartners @LJMU_Health https://t.co/udlwz7lIdG https://t.co/N6PSUqmxFs

Jun 4, 2022 · 3 likes · 2 shares · 1,473 followers View post →
Cristian Añez. FACS
@cristian_anez · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 268 followers View post →
Gabriel Puche, MD/PhD
@gabi_puchepalao · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 8,374 followers View post →
Dani Salas
@pollitodeanaga · X

RT @Manugrillo2: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants #DOACS https://t.co/cdgv8HsOq1 vía @JAMACa…

Jun 3, 2022 · 1 share · 411 followers View post →
Geriatria DrGallegos
@geriatriachile · X

RT @DrDeLasSalasGER: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | J…

Jun 3, 2022 · 3 shares · 1,661 followers View post →
BEATCME
@CmeBeat · X

Great work @bbikdeli @farbod_ZT @psadeghipour @AzitaTalasaz @DebSiegal @mmonrealriete @DJC6998 @connors_md @GBarnesMD @sahilparikhmd @ajaykirtane @RenatoDLopes1 @DLBHATTMD @IsthPresident @Drroxmehran @hmkyale https://t.co/X7VUK8cxi4 #DOACs #VTE #AF

Jun 3, 2022 · 7 likes · 54 followers View post →
Michel Perez Garzon
@MichelPerezGar7 · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | JAMA Cardiology | JAMA Network https://t.co/PUYA89BsTh

Jun 3, 2022 · 159 followers View post →
Carlos Andrés Celis-Preciado
@pulmonology101 · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 4,345 followers View post →
Jorge Cárdenas R.
@JoCardR · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 339 followers View post →
Behnood Bikdeli
@bbikdeli · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 1,267 followers View post →
Geoff Barnes
@GBarnesMD · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 5,373 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 2,716 followers View post →
Manu Morales Sánchez
@Manugrillo2 · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants #DOACS https://t.co/cdgv8HsOq1 vía @JAMACardio part of @JAMANetwork

Jun 3, 2022 · 1 like · 1 share · 2,135 followers View post →
trombo.info
@tromboinfo · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 1,592 followers View post →
Jaime Alvarado
@jaialv01 · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 230 followers View post →
Geraldine POENOU
@zudenstein · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 401 followers View post →
David Jiménez
@DJC6998 · X

RT @mmonrealriete: Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for prima…

Jun 3, 2022 · 16 shares · 1,421 followers View post →
manuel monreal
@mmonrealriete · X

Dose adjustment of DOACs should not be used for acute VTE therapy In contrast, low-intensity DOACs may be used for primary or secondary VTE prevention Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review https://t.co/Dm1xmIbP3W

Jun 3, 2022 · 31 likes · 16 shares · 2,097 followers View post →
ELVIRA LARA
@ElviraLaraCuest · X

RT @TaniaAhuja:

Jun 3, 2022 · 3 shares · 101 followers View post →
Andrés Felipe
@AndrsBillut47 · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jun 2, 2022 · 11 shares · 58 followers View post →
Azita Talasaz, PharmD
@AzitaTalasaz · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jun 2, 2022 · 11 shares · 273 followers View post →
Behnood Bikdeli
@bbikdeli · X

RT @JAMACardio: This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolis…

Jun 2, 2022 · 11 shares · 1,267 followers View post →
JAMA Cardiology
@JAMACardio · X

This review evaluates dose-reduced direct oral anticoagulants (DOAC) for atrial fibrillation (AF) and venous thromboembolism (VTE). Dose-adjustment is relevant for AF and shouldn't be used for VTE. Low-intensity tx may be used for VTE prevention. @bbikdeli https://t.co/rCkTvaNG2h

Jun 2, 2022 · 22 likes · 11 shares · 48,131 followers View post →
alfonso piñana lopez
@AlfonsoPinanaMF · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 474 followers View post →
Luiz Gonzaga! - BaiãoEterno!_A Capacitância! - NE!
@A_Capacitancia · X

RT @bbikdeli: @luistrombo Thanks so much! Here it is: https://t.co/LVhyAxbSRi

Jun 2, 2022 · 2 shares · 376 followers View post →
trombo.info
@tromboinfo · X

RT @TaniaAhuja:

Jun 2, 2022 · 3 shares · 1,592 followers View post →
Dr.SGanta@PharmD
@SaiduluGanta · X

RT @bbikdeli: @luistrombo Thanks so much! Here it is: https://t.co/LVhyAxbSRi

Jun 2, 2022 · 2 shares · 769 followers View post →
Mari Carmen Porres
@LaPorres · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 10,703 followers View post →
Ivan Mendoza
@mencardio · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 7,241 followers View post →
Nicola Veronese
@ilmannato · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 575 followers View post →
Xtian_ sci hub
@Xtian_tuck · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 30,842 followers View post →
Juan
@Juan81849119 · X

RT @SeguraCardio:

Jun 2, 2022 · 2 shares · 31 followers View post →
Dr Raul Hera Jimenez
@rhj_74 · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 699 followers View post →
Manuel Méndez
@mendez_bailon · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 7,795 followers View post →
andres zapata
@andresparana · X

RT @fikkumamoto: Jama cardiology - Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/zH76fPkfuQ…

Jun 2, 2022 · 1 share · 124 followers View post →
andres zapata
@andresparana · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 124 followers View post →
Manuel Gaxiola
@cardiogax · X

RT @SeguraCardio:

Jun 2, 2022 · 2 shares · 7,995 followers View post →
Diego Segura-Rodríguez
@SeguraCardio · X

Jun 2, 2022 · 9 likes · 2 shares · 26,008 followers View post →
Medtorek
@Medtorek · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 13,814 followers View post →
Paco Tarazona
@Sabater71 · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 1,218 followers View post →
Miguel Marcos
@drmiguelmarcos · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 57,788 followers View post →
Ferran Roca
@roca_ferran · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 2,193 followers View post →
Francesc Formiga
@FormigaFrancesc · X

RT @FormigaFrancesc: BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMAC…

Jun 2, 2022 · 12 shares · 1,970 followers View post →
Francesc Formiga
@FormigaFrancesc · X

BASIC: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/38BkS58com @JAMACardio @JAMANetwork @fikkumamoto @vic_pallares @Medtorek @chemachir @QuirosLopezRaul @mendez_bailon @drmiguelmarcos @roca_ferran @DrMarthaGulati @GiuseppeGalati_

Jun 2, 2022 · 28 likes · 12 shares · 1,970 followers View post →
Arturo
@cardiogeriatra · X

RT @DrDeLasSalasGER: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | J…

Jun 1, 2022 · 3 shares · 593 followers View post →
Jaime A. Hidalgo A.
@Jhidalgoanfossi · X

RT @DrDeLasSalasGER: Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | J…

Jun 1, 2022 · 3 shares · 1,877 followers View post →
DeLasSalas
@DrDeLasSalasGER · X

Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review | Venous Thromboembolism | JAMA Cardiology | JAMA Network https://t.co/nF3W3w7oFw

Jun 1, 2022 · 3 likes · 3 shares · 696 followers View post →
Italo Kumamoto
@fikkumamoto · X

Jama cardiology - Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants https://t.co/zH76fPkfuQ via @JAMACardio part of @JAMANetwork

Jun 1, 2022 · 15 likes · 1 share · 8,796 followers View post →
Behnood Bikdeli
@bbikdeli · X

@luistrombo Thanks so much! Here it is: https://t.co/LVhyAxbSRi

Jun 1, 2022 · 6 likes · 2 shares · 1,267 followers View post →
Tania Ahuja
@TaniaAhuja · X

Jun 1, 2022 · 7 likes · 3 shares · 1,045 followers View post →
_Điều chỉnh liều DOAC theo HDSD_VNODIC.pdf
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doi:10.1001/jamacardio.2022.1292 2. Công ty Bayer AG (2019), "Tờ thông tin sản phẩm Xarelto 15mg, 20mg” 3. Công ty Bayer AG (2017), "Tờ thông tin sản phẩm ...

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