Transl Neurodegener June 2022 PMID 35659112

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases.

Kareem Khalaf, Paolo Tornese, Antoniangela Cocco, Alberto Albanese

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Mentions

Peak: 16 in Dec 2022

across 4 sources since Jun 2022

Extended reach

509,096

potential audience

Total likes

13,623

Video views

366,854

Mentions per month

Jun 2022 – Mar 2025

Where it's discussed

X / Twitter39 posts
Bluesky5 posts
YouTube3 videos
News2 articles

AI synopsis

What people are saying

Discussions consistently show a positive tone, with users highlighting promising studies, such as references to 'amazing studies' and 'potential OTC supplement', and urging others to investigate TUDCA further. The tone's optimism and the use of phrases like 'help neurodegeneration' demonstrate genuine interest and an implied hope for future impacts, though the overall depth remains moderate.

AgreementModerate agreement

Most discussions express support or positive perceptions of TUDCA's potential benefits for neurodegenerative diseases, reflected in phrases like 'promising results' and 'amazing studies'.

InterestHigh interest

There is a high level of curiosity and enthusiasm, with users urging others to look into TUDCA and mentioning ongoing research.

EngagementModerate engagement

Few posts delve into detailed mechanisms or critique the research, but many share personal interests or encourage further exploration, indicating moderate engagement.

ImpactModerate impact

While some discussions emphasize potential therapeutic impacts, most focus on raising awareness or sparking interest rather than definitive clinical applications yet.

Abstract in brief

TUDCA, a hydrophilic bile acid, has shown antiapoptotic and neuroprotective effects in experimental models of neurodegenerative diseases like Alzheimer’s, Parkinson’s, Huntington’s, and ALS, by reducing oxidative stress, protecting mitochondria, and maintaining proper protein folding.
Preclinical studies suggest that TUDCA works by inhibiting cell death pathways, reducing inflammation, and acting as a chemical chaperone, which helps prevent protein misfolding and aggregation common in these diseases.
Clinical trials, particularly in ALS, indicate that TUDCA is safe and may slow disease progression, making it a promising therapeutic option while further research continues to explore its benefits for other neurodegenerative conditions.

Read the full abstract

All mentions

Tauroursodeoxycholic Acid as a Neuroprotective Agent in Neurodegenerative Diseases

TUDCA, a hydrophilic bile acid, shows antiapoptotic and neuroprotective effects by reducing oxidative stress and maintaining protein folding, with potential to slow progression in diseases like Alzheimer's, Parkinson's…

Dr. Eric Berg DC · Dec 27, 2022 220,184 views

TUDCA as a Potential Therapeutic for Neurodegenerative Diseases

TUDCA, a hydrophilic bile acid, has shown antiapoptotic and neuroprotective effects in experimental models of neurodegenerative diseases like Alzheimer’s, Parkinson’s, Huntington’s, and ALS, by reducing oxidative…

Dr. Berg - официальный русскоязычный канал · Feb 1, 2023 145,263 views

TUDCA as a Neuroprotective Agent in Neurodegenerative Diseases

Happy Namynara · Feb 18, 2024 1,407 views

ES/IODE

@esiode.bsky.social · Bluesky

Mar 11, 2025 View post →

ES/IODE

@esiode.bsky.social · Bluesky

Feb 4, 2025 View post →

ES/IODE

@esiode.bsky.social · Bluesky

Dec 29, 2024 View post →

ES/IODE

@esiode.bsky.social · Bluesky

Nov 3, 2024 View post →

Actually Mik

@140_keyes · X

@CCVagina So sorry, neurodegenerative crap sucks. My husband is in early stage HD and has seen some improvements since starting TUDCA. Clinical trials are not complete, but promising results from an OTC supplement. https://t.co/VcqsNbFOfS.

Oct 31, 2024 · 316 followers View post →

ES/IODE

@esiode.bsky.social · Bluesky

Oct 13, 2024 View post →

Ekhi

@Ekhi_sasienGain · X

Selenium has antiviral properties as well as mito enhancer. Other antioxidants: Ginkgo TUDCA could be a potential OTC to add to https://t.co/CUp1y8M9IO https://t.co/hIks4EZrHc

Mar 19, 2024 · 5 likes · 564 followers View post →

Claus Zsivkovits

@ClausZsivkovits · X

RT @healthmatrixnet: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/uEZ1JulMI6

Jan 24, 2024 · 2 shares · 235 followers View post →

Jacques Paquin

@JacquesPaquin8 · X

RT @healthmatrixnet: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/uEZ1JulMI6

Jan 23, 2024 · 2 shares · 257 followers View post →

Dr.Gaby

@healthmatrixnet · X

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/uEZ1JulMI6

Jan 23, 2024 · 1 like · 2 shares · 1,220 followers View post →

Herbert Renz-Polster

@RenzPolster · X

RT @renesugar: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/0YBIZwNWzP https://t.co/…

Aug 15, 2023 · 2 shares · 8,584 followers View post →

Tomaso Antonacci

@TomasoAntonacci · X

RT @renesugar: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/0YBIZwNWzP https://t.co/…

Aug 15, 2023 · 2 shares · 2,390 followers View post →

Rene Sugar

@renesugar · X

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/0YBIZwNWzP https://t.co/XvCyJbr3mP

Aug 15, 2023 · 12 likes · 2 shares · 3,950 followers View post →

Encarnación Martín

@Encarna1m · X

@cherylbenson @RenzPolster @lifeanalytics Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/gfbxiA9S2t

Jul 11, 2023 · 4 likes · 293 followers View post →

Ashley

@Laughterizbest · X

@MikeOMara @meccamaggie At the very least, please look into TUDCA. Some amazing studies coming out on how it helps neurodegeneration https://t.co/zTfDfkdWcU

Apr 29, 2023 · 1 like · 937 followers View post →

es/iode

@es_iode · X

Apr 14, 2023 · 36 followers View post →

es/iode

@es_iode · X

Apr 13, 2023 · 36 followers View post →

NootBro

@nootropicguy · X

@StuMcMullin @BowTiedUM https://t.co/OTxT2XQ8Th

Apr 6, 2023 · 1 like · 80,915 followers View post →

Ashley

@Laughterizbest · X

@nootropicguy I take all except Sodium Butyrate, will have to look into it! The more I read about TUDCA the more I'm amazed by it's healing properties. Dunno why it's not discussed more, especially for it's benefits for neurodegenerative issues https://t.co/zTfDfkdWcU

Mar 18, 2023 · 937 followers View post →

Unravel

@tothineownselph · X

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases | Translational Neurodegeneration | Full Text https://t.co/sFhCKZOn3l

Mar 4, 2023 · 605 followers View post →

Gerard Hough

@GerardHough · X

https://t.co/cKBOXJF3zD Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases

Feb 28, 2023 · 1,747 followers View post →

Михаил Рохин 99+

@MikhailRokhin · X

#Генетика #предрасположенность к болезни #Альцгеймер ? https://t.co/TiLBFl5X3M через @YouTube ...и консультация у #эндокринолог ( #гормоны щитовидки, гипофиза и надпочечников) ... иммунная система <-> эндокринная система <-> нервная система

Feb 1, 2023 · 62 followers View post →

es/iode

@es_iode · X

Jan 26, 2023 · 36 followers View post →

es/iode

@es_iode · X

Jan 21, 2023 · 36 followers View post →

نوفـﮧ

@Nunnita_ · X

@chrishemsworth @NatGeo @DisneyPlus https://t.co/MYAYN63tcV Try this! It’ll help you prevent Alzheimer’s. Dr berg recommendations truly works.

Jan 19, 2023 · 24 followers View post →

Yi Xue

@ArtyExeter · X

@peterzhou8964 https://t.co/N8oah0MgD4

Jan 6, 2023 · 1 like · 1,676 followers View post →

melissa zickler

@colormemod · X

Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/hdGZfbhW1U via @YouTube

Dec 27, 2022 · 523 followers View post →

Kitty Glamourcat

@kittyglamourcat · X

Dr Eric Berg - Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/x1S8DFDj7L via @YouTube

Dec 27, 2022 · 1,945 followers View post →

Vielä Hengissä

@JukMantu · X

Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/cBhKWBpXHG käyttäen @YouTube

Dec 27, 2022 · 6,035 followers View post →

Bona Na Croin

@BonaNaCroin · X

RT @BobobroK: Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/fbllptgWwi

Dec 27, 2022 · 2 shares · 2,202 followers View post →

joonbug0861

@joonbug0861 · X

RT @BobobroK: Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/fbllptgWwi

Dec 27, 2022 · 2 shares · 2,047 followers View post →

BOBObro kake

@BobobroK · X

Genetically at Risk for Alzheimer's Disease? DO THIS... https://t.co/fbllptgWwi

Dec 27, 2022 · 2 likes · 2 shares · 3,399 followers View post →

Gerald Schumacher

@GeraldSaved285 · X

https://t.co/zEBLURgMXS

Dec 27, 2022 · 670 followers View post →

John Hansen

@johnhansenart · X

Dec 27, 2022 · 2 likes · 112 followers View post →

Ruben vasquez

@Rubenva65000956 · X

RT @GoPoloe: If You Are Genetically at Risk for Alzheimer's Disease, DO THIS NOW.. https://t.co/Ee4BM6LPZ5 via @YouTube

Dec 27, 2022 · 1 share · 2,436 followers View post →

Omar Lemfadel

@omar_lemfadel · X

https://t.co/kBOBEZQSyO

Dec 27, 2022 · 186 followers View post →

Sir Poloe -Kid of Grace-Son of Nun

@GoPoloe · X

If You Are Genetically at Risk for Alzheimer's Disease, DO THIS NOW.. https://t.co/Ee4BM6LPZ5 via @YouTube

Dec 27, 2022 · 1 like · 1 share · 3,640 followers View post →

仲本正吉

@ygfUYTbPZvNlitJ · X

If You Are Genetically at Risk for Alzheimer's Disease, DO THIS NOW.. https://t.co/wl81UTw1kN @YouTubeより

Dec 27, 2022 · 4 followers View post →

Yuji Marutani Planning Director

@YujiMarutani · X

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/qF7LLxB24N

Dec 25, 2022 · 1,581 followers View post →

Steven Mathern

@StevenMathern · X

@philena_pugh @louise_linney @1goodtern i absolutely want to know this too; it seems udca is an antagonist while tudca is an agonist yet look at these potential effects: https://t.co/ePj7YpAzix

Dec 17, 2022 · 456 followers View post →

Steven Mathern

@StevenMathern · X

@BiologistBunk what do u think about restoring mitochondrial function via the oral supplement tudca?: https://t.co/ePj7YpAzix

Dec 17, 2022 · 456 followers View post →

Alberto Albanese

@AlbertoAlbanes5 · X

A review on the use of bile acids as disease modifiers in neurodegenerative diseases. Paper can be downloaded at https://t.co/eJNbZhJOuz.

Jun 7, 2022 · 326 followers View post →

The Science of Parkinson's

@ScienceofPD · X

With the "UP study" results imminent, this is very timely: Tauroursodeoxycholic acid - a new review from @AlbertoAlbanes5 & colleagues asks if it is a potential therapeutic tool in neurodegenerative conditions, like #Parkinsons https://t.co/zy79Y16jQ2 https://t.co/TGG1uTESRa

Jun 7, 2022 · 10,871 followers View post →

Paperbirds_Neurology

@PaperbirdsN · X

New article: Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases https://t.co/T9Kg1X35iN #alzheimers #neurology https://t.co/GD6TDguYou

Jun 6, 2022 · 458 followers View post →

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Tauroursodeoxycholic Acid as a Neuroprotective Agent in Neurodegenerative Diseases

TUDCA as a Potential Therapeutic for Neurodegenerative Diseases

TUDCA as a Neuroprotective Agent in Neurodegenerative Diseases