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Front Pediatr May 2022 PMID 35685915

Pathogenicity and Long-Term Outcomes of Liddle Syndrome Caused by a Nonsense Mutation of in a Chinese Family.

Di Zhang, Yi Qu, Xue-Qi Dong, Yi-Ting Lu, Kun-Qi Yang, Xin-Chang Liu, Peng Fan, Yu-Xiao Hu, Chun-Xue Yang, Ling-Gen Gao, Ya-Xin Liu, Xian-Liang Zhou

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Mentions

4
Peak: 3 in Jun 2022
across 2 sources since Jun 2022

Extended reach

11,319
potential audience

Total likes

5

Video views

20

Mentions per month

Jun 2022 – Aug 2025

Where it's discussed

  • X / Twitter3 posts
  • YouTube1 videos

AI synopsis

What people are saying

These discussions mainly serve to share the publication's findings, such as highlighting the genetic mutation in the Chinese family and the effectiveness of amiloride, but do not delve deeply into methodological details or clinical implications. The tone remains informational, with references to source attribution and hashtags indicating focus on dissemination rather than detailed critique or debate.

AgreementNeither agree nor disagree

The discussions mainly acknowledge the significance of the study, but do not strongly express support or disagreement with its conclusions.

InterestModerate interest

The social discussions show a moderate level of curiosity, especially regarding the genetic aspects and treatment implications of Liddle syndrome.

EngagementLow engagement

Most posts are brief, primarily sharing links or calling attention to the publication without deep analysis or detailed commentary.

ImpactNeutral impact

The posts reflect some awareness but lack evidence of widespread influence or behavioral change resulting from the publication.

Abstract in brief

  • Liddle syndrome is a genetic condition that causes high blood pressure, often starting in childhood, and this study investigates a specific mutation in a family from China along with the effectiveness of amiloride, a medication used to manage the condition.
  • Researchers used lab techniques to analyze the mutation's effects on sodium channels and found that patients with the mutation had heightened responses to amiloride.
  • The long-term treatment with amiloride successfully controlled blood pressure without adverse effects, highlighting its potential as a safe and effective strategy for managing Liddle syndrome in young patients.
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Top posts

Most liked on X and Bluesky
American Society of Pediatric Nephrology
@ASPNeph · X

Pathogenicity and Long-Term Outcomes of #Liddle_Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family https://t.co/hDns1VqfUG @FrontPediatrics #openaccess #HTN

Jun 11, 2022 · 2 likes · 2 shares · 10,134 followers View post →
International Pediatric Hypertension Association
@IntPedHTN · X

Pathogenicity and Long-Term Outcomes of #Liddle_Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family https://t.co/niFW2QKu8P @FrontPediatrics #openaccess #HTN

Jun 10, 2022 · 1 like · 614 followers View post →

All mentions

Dark Brandon Rises
@iamgabbarson · X

RT @ASPNeph: Pathogenicity and Long-Term Outcomes of #Liddle_Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family https://t…

Jun 11, 2022 · 2 shares · 544 followers View post →
American Society of Pediatric Nephrology
@ASPNeph · X

Pathogenicity and Long-Term Outcomes of #Liddle_Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family https://t.co/hDns1VqfUG @FrontPediatrics #openaccess #HTN

Jun 11, 2022 · 2 likes · 2 shares · 10,134 followers View post →
International Pediatric Hypertension Association
@IntPedHTN · X

Pathogenicity and Long-Term Outcomes of #Liddle_Syndrome Caused by a Nonsense Mutation of SCNN1G in a Chinese Family https://t.co/niFW2QKu8P @FrontPediatrics #openaccess #HTN

Jun 10, 2022 · 1 like · 614 followers View post →