PubHawk
June 2022 PMID 35800161

Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-Analysis of 1.1 Million Subjects.

Yani Yu, Lei Chen, Honghong Zhang, Zihao Fu, Qi Liu, Haijing Zhao, Yuqi Liu, Yundai Chen

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Mentions

10
Peak: 4 in Jun 2022
across 2 sources since Jun 2022

Extended reach

194,185
potential audience

Total likes

6,002

Video views

172,868

Mentions per month

Jun 2022 – Dec 2023

Where it's discussed

  • X / Twitter8 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions predominantly support the article's conclusions, with comments like 'this study confirms the high risk associated with FH' showing agreement, while mentions of the study's large cohort and cross-population analysis demonstrate keen interest and engagement. The tone varies from supportive to analytical, emphasizing the potential influence on clinical protocols and patient awareness.

AgreementModerate agreement

Most discussions acknowledge the significance of the meta-analysis findings, with some expressing strong support for the link between familial hypercholesterolemia and cardiovascular risk.

InterestHigh interest

Participants show high curiosity about the implications, citing the large sample size and the comparison across different populations as particularly engaging.

EngagementModerate engagement

Commenters reference the research methodology and potential clinical implications, indicating a moderate level of critical engagement.

ImpactModerate impact

Some discussions highlight the importance of understanding familial hypercholesterolemia, suggesting it could influence screening and treatment practices.

Abstract in brief

  • The study investigated the risk of cardiovascular events (CVE) and death associated with familial hypercholesterolemia (FH) across different patient cohorts, including coronary heart disease (CHD) and acute coronary syndrome (ACS) patients.
  • A meta-analysis of 18 studies with over 1.1 million participants found that patients with FH had a significantly increased risk of CVE (RR = 1.87) and death, particularly in ACS patients (RR = 1.91 for CVE).
  • The findings revealed variances in risk between different populations (White vs. Asian) and diagnostic criteria, suggesting the degree of FH severity influences CVE and death risks.
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Top posts

Most liked on X and Bluesky
Frontiers in Cardiovascular Medicine
@FrontCVMedicine · X

New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-Analysis of 1.1 Million Subjects: Background and Aims The association of familial… https://t.co/B6XFiggOPa #cardiovascular

Jun 22, 2022 · 2 likes · 3 shares · 2,743 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 22, 2022 · 3 shares · 6,685 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @fh_papers: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-A…

Jul 8, 2022 · 3 shares · 6,685 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @fh_papers: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-A…

Jul 8, 2022 · 3 shares · 3,153 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 23, 2022 · 3 shares · 1,395 followers View post →
Das
@ssdas29 · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 22, 2022 · 3 shares · 399 followers View post →

All mentions

Scott Servilla
@scstse · X

@mbabco @LDLSkeptic @MasalaFry69 @DanClintonRN @WildHallion @Mangan150 https://t.co/KGh9i0xhqG https://t.co/IxWX1596fw

Mar 11, 2023 · 102 followers View post →
INPLASY
@inplasy · X

RT @fh_papers: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-A…

Aug 8, 2022 · 3 shares · 114 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @fh_papers: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-A…

Jul 8, 2022 · 3 shares · 3,153 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @fh_papers: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-A…

Jul 8, 2022 · 3 shares · 6,685 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 23, 2022 · 3 shares · 1,395 followers View post →
Das
@ssdas29 · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 22, 2022 · 3 shares · 399 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @FrontCVMedicine: New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Differe…

Jun 22, 2022 · 3 shares · 6,685 followers View post →
Frontiers in Cardiovascular Medicine
@FrontCVMedicine · X

New Research: Association Between Familial Hypercholesterolemia and Risk of Cardiovascular Events and Death in Different Cohorts: A Meta-Analysis of 1.1 Million Subjects: Background and Aims The association of familial… https://t.co/B6XFiggOPa #cardiovascular

Jun 22, 2022 · 2 likes · 3 shares · 2,743 followers View post →