Molecules July 2022 PMID 35807558

Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review.

Vivek P Chavda, Jinal Ajabiya, Divya Teli, Joanna Bojarska, Vasso Apostolopoulos

Mentions

28
Peak: 5 in Feb 2023
across 3 sources since Feb 2023

Extended reach

148,035
potential audience

Total likes

69

Video views

4,755

Mentions per month

Feb 2023 – Aug 2024

Where it's discussed

  • News18 articles
  • X / Twitter8 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussion reflects moderate enthusiasm and engagement, with posts highlighting its weekly injections, effects on insulin and glucagon, and potential to revolutionize diabetes and obesity treatments. The tone suggests cautious optimism, exemplified by phrases like 'new era' and 'promising', while some comments focus on mechanisms like gastric emptying and insulin secretion, indicating analytical interest.

AgreementModerate agreement

Most discussions acknowledge the promising aspects of Tirzepatide and its dual-targeted approach, indicating general support.

InterestModerate interest

The conversations show moderate interest, with participants discussing mechanisms and potential benefits but not expressing extreme enthusiasm or skepticism.

EngagementModerate engagement

Some posts delve into specific physiological effects such as reductions in gastric emptying and glucagon secretion, reflecting a moderate level of discussion depth.

ImpactNeutral impact

The overall influence appears balanced: the publication seems significant but not revolutionary in the immediate context, with some posts referencing new treatment possibilities.

Abstract in brief

  • Tirzepatide, known as a "twincretin," is a groundbreaking drug that targets both GLP-1 and GIP receptors, helping to control blood sugar, improve insulin sensitivity, and significantly reduce body weight, making it a promising treatment for obesity and diabetes.
  • The drug is a synthetic peptide with a design that allows it to be injected weekly, thanks to its ability to bind albumin and its half-life of around five days; it was approved by the FDA in May 2022 under the brand name Mounjaro.
  • This development marks the beginning of the "twincretin era," providing a new dual-treatment option that offers advantages for managing diabetes, obesity, and related cardiometabolic conditions, although ongoing research continues to explore its full potential and limitations.

Top posts

Most liked on X and Bluesky
Molecules MDPI
@Molecules_MDPI · X

#mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review” By: Vivek P. Chavda, et al.

Feb 20, 2023 · 8 likes · 5 shares · 7,661 followers View post →
Neil Floch MD
@NeilFlochMD · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 130,124 followers View post →
Wouter ont-dekker
@ontdekuzelf · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 1,832 followers View post →
Dr. Alexander Carreño G.
@ChemistryandBi1 · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 1,497 followers View post →
oryzae
@nonshu · X

抗肥満薬Tirzepatide "GLP-1受容体作動薬はα細胞を介して膵臓のグルカゴン分泌を減少させ、胃内容排出時間を短縮し、食欲と栄養素の摂取を減少させ、体重減少を引き起こす。" https://t.co/pfeGydXGv1

Aug 30, 2024 · 616 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 20, 2023 · 5 shares · 574 followers View post →

All mentions

oryzae
@nonshu · X

抗肥満薬Tirzepatide "GLP-1受容体作動薬はα細胞を介して膵臓のグルカゴン分泌を減少させ、胃内容排出時間を短縮し、食欲と栄養素の摂取を減少させ、体重減少を引き起こす。" https://t.co/pfeGydXGv1

Aug 30, 2024 · 616 followers View post →
Suresh
@Stlite5 · X

@baxirahul Tirzepatide once a week injections reduces gastric emptying and decreases glucagon secretions and increase insulin secretions https://t.co/lfFv5wSCk0 https://t.co/63GlRM43tc

Dec 26, 2023 · 437 followers View post →
Albert Kagina Sinyigaya
@DrSinyigaya · X

Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review https://t.co/QWDZ39elzW

Nov 30, 2023 · 490 followers View post →
Wouter ont-dekker
@ontdekuzelf · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 1,832 followers View post →
Neil Floch MD
@NeilFlochMD · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 130,124 followers View post →
Dr. Alexander Carreño G.
@ChemistryandBi1 · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 21, 2023 · 5 shares · 1,497 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @Molecules_MDPI: #mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obes…

Feb 20, 2023 · 5 shares · 574 followers View post →
Molecules MDPI
@Molecules_MDPI · X

#mdpimolecules #NewPublication New Publication “Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review” By: Vivek P. Chavda, et al.

Feb 20, 2023 · 8 likes · 5 shares · 7,661 followers View post →