Neuron September 2022 PMID 35809573

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons.

Fuu-Jiun Hwang, Richard H Roth, Yu-Wei Wu, Yue Sun, Destany K Kwon, Yu Liu, Jun B Ding

Mentions

96
Peak: 38 in Jul 2022
across 6 sources since Oct 2021

Extended reach

923,165
potential audience

Total likes

225

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Oct 2021 – May 2025

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AI synopsis

What people are saying

The discussions highlight the relevance of the publication, with references to the exciting observations made by Stanford researchers about memory formation and motor circuits in mice. Phrases like 'the cool stuff!' and discussions revolving around memory reactivation contribute to a tone of excitement and importance, showcasing a strong interest in how this research could enhance understanding of diseases like Parkinson's.

AgreementModerate agreement

The majority of the discussions show a supportive stance towards the findings of the research.

InterestHigh interest

There is evident enthusiasm and curiosity about the implications of the research.

EngagementModerate engagement

While some comments are informative, most mainly express interest without deep analytical discussion.

ImpactHigh impact

Many participants perceive the research as having significant implications for understanding learning and memory processes.

Abstract in brief

  • Motor learning involves changes in the brain's motor cortex (M1) and striatum, crucial for forming motor skill memories.
  • Researchers trained mice on a motor task and manipulated specific neurons to understand how these neurons strengthen connections during learning.
  • Findings show that successful motor performance is linked to the reactivation of certain M1 neurons, which undergo structural changes and enhance their connections to other brain cells involved in coordinating movement.

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CLaE
@leafs_s · X

Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 37 likes · 7 shares · 28,125 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu #biorxiv_neursci

Oct 29, 2021 · 22 likes · 4 shares · 59,897 followers View post →
yuweiwu_imb
@yuweiwu_imb · X

Congratulations to Fuu-jiun and Richard! Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons is out on Neuron! We used TRAP and synaptic mapping to reveal the clustered synapses form in the striatum. https://t.co/uW7RcNglOl

Jul 8, 2022 · 19 likes · 293 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons” by Fuu-Jiun Hwang et al. Neuron https://t.co/7FNVFcksQs

Jul 18, 2022 · 11 likes · 2 shares · 505,549 followers View post →
Takuma Kitanishi
@tkitanishi · X

運動学習で運動野エングラム細胞→線条体シナプスが強くなる。 Neuron 2022. Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons. https://t.co/n2kg7p8VuW

Jul 18, 2022 · 9 likes · 1 share · 2,692 followers View post →
Josh Goldberg Lab
@GoldbergLab · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/NLo2qnp4QO

Jul 16, 2022 · 8 likes · 1,317 followers View post →

All mentions

The Carboncopies Foundation
@carboncopiesorg · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses o…

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Kenneth Hayworth
@KennethHayworth · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses o…

May 6, 2025 · 2 shares · 2,320 followers View post →
Aspirational Neuroscience
@AspirationNeuro · X

Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" https://t.co/BK7jb2lpcp #Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience https://t.co/JIY3sE73iv

May 5, 2025 · 2 likes · 2 shares · 630 followers View post →
Aspirational Neuroscience
@aspirationalneuro.bsky.social · Bluesky

Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" carboncopies.org/Events/Journ... #Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience

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@ariel_zj · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! - Motor learning selectively strengthens cortical and striatal synapses…

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The Carboncopies Foundation
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RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! - Motor learning selectively strengthens cortical and striatal synapses…

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Liangyi Chen
@Orangeroad2017 · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! - Motor learning selectively strengthens cortical and striatal synapses…

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Kenneth Hayworth
@KennethHayworth · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! - Motor learning selectively strengthens cortical and striatal synapses…

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Aspirational Neuroscience
@AspirationNeuro · X

Join Us for the Memory Decoding Journal Club! - Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/bei9gKPCFd... #Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience https://t.co/zGndvEw6m6

May 4, 2025 · 6 likes · 4 shares · 630 followers View post →
Aspirational Neuroscience
@aspirationalneuro.bsky.social · Bluesky

Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" carboncopies.org/Events/Journ... #Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience

May 4, 2025 · 3 likes View post →
The Carboncopies Foundation
@carboncopiesorg · X

RT @AspirationNeuro: Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses o…

Apr 28, 2025 · 1 share · 732 followers View post →
Aspirational Neuroscience
@AspirationNeuro · X

Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" May 6, 3 pm PDT at https://t.co/a4oXNpc4AO https://t.co/J1kEbRXKcJ

Apr 28, 2025 · 2 likes · 1 share · 630 followers View post →
Çağlar Mesci
@caglarmesci · X

RT @caglarmesci: Stanford neuroscientists observe memory formation in real time https://t.co/iBSZrnVyTd https://t.co/UtfnIPONaU

Feb 28, 2024 · 4 shares · 852 followers View post →
Çağlar Mesci
@caglarmesci · X

RT @caglarmesci: Stanford neuroscientists observe memory formation in real time https://t.co/iBSZrnVyTd https://t.co/UtfnIPONaU

Dec 25, 2023 · 4 shares · 852 followers View post →
Çağlar Mesci
@caglarmesci · X

RT @caglarmesci: Stanford neuroscientists observe memory formation in real time https://t.co/iBSZrnVyTd https://t.co/UtfnIPONaU

Sep 20, 2023 · 4 shares · 852 followers View post →
Stanford Knight Initiative for Brain Resilience
@BrainResilience · X

RT @StanfordBrain: It's #BrainAwarenessWeek— let's take a moment to appreciate new technologies that make it possible for Stanford neurosci…

Mar 18, 2023 · 1 share · 840 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

It's #BrainAwarenessWeek— let's take a moment to appreciate new technologies that make it possible for Stanford neuroscientists to observe memory formation in real time. https://t.co/mAtBT4vHDd

Mar 18, 2023 · 7 likes · 1 share · 10,976 followers View post →
Çağlar Mesci
@caglarmesci · X

RT @caglarmesci: Stanford neuroscientists observe memory formation in real time https://t.co/iBSZrnVyTd https://t.co/UtfnIPONaU

Sep 24, 2022 · 4 shares · 852 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/n19mGZOfKl @Stanford_Neuro @StanfordNsurg

Aug 25, 2022 · 2 likes · 1 share · 10,976 followers View post →
Çağlar Mesci
@caglarmesci · X

Hwang, F-J, Roth, RH, Wu, Y-W, Sun, Y, Kwon, DK, Liu, Y, Ding, J. Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons. Neuron. Published online July 8, 2022. DOI: https://t.co/hBuvbS75gx https://t.co/U0YADB2uby

Aug 20, 2022 · 849 followers View post →
Çağlar Mesci
@caglarmesci · X

Stanford neuroscientists observe memory formation in real time https://t.co/iBSZrnVyTd https://t.co/UtfnIPONaU

Aug 20, 2022 · 4 shares · 852 followers View post →
Stanford Neurology & Neurological Sciences
@Stanford_Neuro · X

RT @StanfordBrain: As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #bra…

Aug 8, 2022 · 4 shares · 5,062 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/ZxsEdkAZFb @Stanford_Neuro @StanfordNsurg

Aug 8, 2022 · 1 like · 4 shares · 10,976 followers View post →
Miguel Angel Escotet
@DrEscotet · X

RT @DrEscotet: Stanford researchers observe memory formation in real-time. Why is it that someone who hasn’t ridden a bicycle in decades ca…

Aug 2, 2022 · 4 shares · 9,737 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/eBAiPd8Lds @Stanford_Neuro @StanfordNsurg

Jul 29, 2022 · 7 likes · 6 shares · 10,976 followers View post →
BRIC-NBRC
@DBT_NBRC · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 29, 2022 · 7 shares · 4,740 followers View post →
えばしゅう
@koburouze845 · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 29, 2022 · 7 shares · 2,177 followers View post →
Gustavo cabañas
@Gcabanasmoreno · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 7 shares · 11 followers View post →
Nathalie George
@nathgeorgeNG · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 7 shares · 248 followers View post →
Eino-Mikael Talvitie
@EinoMikael · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 7 shares · 18 followers View post →
Andy Xor
@andy_xor · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 7 shares · 1,439 followers View post →
Ben Zarov
@BenZarov · X

RT @leafs_s: Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 7 shares · 269 followers View post →
CLaE
@leafs_s · X

Neuron Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/adNOdxnL5R

Jul 28, 2022 · 37 likes · 7 shares · 28,125 followers View post →
MANUJ TRIPATHI
@manujtripathi · X

RT @DrEscotet: Stanford researchers observe memory formation in real-time. Why is it that someone who hasn’t ridden a bicycle in decades ca…

Jul 25, 2022 · 4 shares · 167 followers View post →
Miguel A. Escotet
@MAEscotet · X

RT @DrEscotet: Stanford researchers observe memory formation in real-time. Why is it that someone who hasn’t ridden a bicycle in decades ca…

Jul 25, 2022 · 4 shares · 1,059 followers View post →
Escotet Foundation
@Escotet · X

RT @DrEscotet: Stanford researchers observe memory formation in real-time. Why is it that someone who hasn’t ridden a bicycle in decades ca…

Jul 25, 2022 · 4 shares · 235 followers View post →
Miguel Angel Escotet
@DrEscotet · X

Stanford researchers observe memory formation in real-time. Why is it that someone who hasn’t ridden a bicycle in decades can likely jump on and ride away, but could not recall a name from their 3rd-grade class? The research was published July 8 in Neuron: https://t.co/vNYWKBuuH0 https://t.co/Z1WHFskNig

Jul 25, 2022 · 5 likes · 4 shares · 9,737 followers View post →
Stanford Neurosurgery
@StanfordNsurg · X

Dr. Jun Ding (@BJunDing) & colleagues observed the formation of skill-based memories in the brains of mice, potentially leading to improved understanding of learning and #Parkinsons disease. @StanfordBrain https://t.co/Glg9dVjw9j

Jul 23, 2022 · 2 likes · 2 shares · 11,314 followers View post →
Stanford Neurology & Neurological Sciences
@Stanford_Neuro · X

RT @StanfordBrain: As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #bra…

Jul 20, 2022 · 1 share · 5,062 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/hR58NKxw2n @Stanford_Neuro @StanfordNsurg

Jul 20, 2022 · 4 likes · 1 share · 10,976 followers View post →
Australasian Neuroscience Society (ANS)
@AusNeuroSoc · X

RT @lab_plotkin: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons: Neuron https://t.co/UWc1cej…

Jul 20, 2022 · 3 shares · 3,687 followers View post →
Pooja Shukla
@HeadsInOcean · X

The cool stuff! https://t.co/jyQTniSfjH

Jul 20, 2022 · 94 followers View post →
Ronald K. Phillips
@Ariella09 · X

Stanford neuroscientists observe memory formation in real time https://t.co/xhLeWimchj

Jul 19, 2022 · 1,315 followers View post →
Lab of Dr. Nephi Stella, University of Washington
@StellaLab11 · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/mJNVOzSFS5

Jul 19, 2022 · 1 like · 756 followers View post →
NaO
@spikeoutOXY · X

RT @NeuroscienceNew: “Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons” by Fuu-Jiun Hwang et a…

Jul 19, 2022 · 2 shares · 153 followers View post →
NaO
@spikeoutOXY · X

RT @tkitanishi: 運動学習で運動野エングラム細胞→線条体シナプスが強くなる。 Neuron 2022. Motor learning selectively strengthens cortical and striatal synapses of motor e…

Jul 19, 2022 · 1 share · 153 followers View post →
Cláudio Bacci
@CBacciBR · X

RT @NeuroscienceNew: “Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons” by Fuu-Jiun Hwang et a…

Jul 18, 2022 · 2 shares · 543 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons” by Fuu-Jiun Hwang et al. Neuron https://t.co/7FNVFcksQs

Jul 18, 2022 · 11 likes · 2 shares · 505,549 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

Que bárbaro!!!!!!! Stanford neuroscientists observe memory formation in real time https://t.co/g7LEEhNyTJ https://t.co/MZzqPJOCwK https://t.co/HDkiyhUztx

Jul 18, 2022 · 93 followers View post →
Takuma Kitanishi
@tkitanishi · X

運動学習で運動野エングラム細胞→線条体シナプスが強くなる。 Neuron 2022. Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons. https://t.co/n2kg7p8VuW

Jul 18, 2022 · 9 likes · 1 share · 2,692 followers View post →
WilluhnLab
@_the_ing · X

RT @lab_plotkin: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons: Neuron https://t.co/UWc1cej…

Jul 18, 2022 · 3 shares · 1,338 followers View post →
Dehorter Lab
@DehorterLab · X

RT @lab_plotkin: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons: Neuron https://t.co/UWc1cej…

Jul 18, 2022 · 3 shares · 1,293 followers View post →
PlotkinLab
@lab_plotkin · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons: Neuron https://t.co/UWc1cejxDD

Jul 17, 2022 · 6 likes · 3 shares · 215 followers View post →
Josh Goldberg Lab
@GoldbergLab · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/NLo2qnp4QO

Jul 16, 2022 · 8 likes · 1,317 followers View post →
h
@mr_sunshine · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4cFGy50ogI

Jul 15, 2022 · 1 like · 3,067 followers View post →
Stanford Neurology & Neurological Sciences
@Stanford_Neuro · X

RT @StanfordBrain: As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #bra…

Jul 14, 2022 · 3 shares · 5,062 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/OTGcOJQE2P @Stanford_Neuro @StanfordNsurg

Jul 14, 2022 · 6 likes · 3 shares · 10,976 followers View post →
Stanford Neurosurgery
@StanfordNsurg · X

RT @StanfordBrain: As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #bra…

Jul 12, 2022 · 3 shares · 11,314 followers View post →
Stanford Neurology & Neurological Sciences
@Stanford_Neuro · X

RT @StanfordBrain: As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #bra…

Jul 12, 2022 · 3 shares · 5,062 followers View post →
Wu Tsai Neurosciences Institute
@StanfordBrain · X

As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: https://t.co/92Ko9NwEK9 @Stanford_Neuro @StanfordNsurg

Jul 12, 2022 · 3 likes · 3 shares · 10,976 followers View post →
yuweiwu_imb
@yuweiwu_imb · X

Congratulations to Fuu-jiun and Richard! Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons is out on Neuron! We used TRAP and synaptic mapping to reveal the clustered synapses form in the striatum. https://t.co/uW7RcNglOl

Jul 8, 2022 · 19 likes · 293 followers View post →
Bergami Lab
@bergami_lab · X

RT @biorxiv_neursci: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu…

Oct 30, 2021 · 4 shares · 558 followers View post →
Raaj Gowrishankar
@outRaajeous · X

RT @biorxiv_neursci: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu…

Oct 29, 2021 · 4 shares · 650 followers View post →
NaO
@spikeoutOXY · X

RT @biorxiv_neursci: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu…

Oct 29, 2021 · 4 shares · 153 followers View post →
Andy Xor
@andy_xor · X

RT @biorxiv_neursci: Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu…

Oct 29, 2021 · 4 shares · 1,439 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/4l0wN97aOu #biorxiv_neursci

Oct 29, 2021 · 22 likes · 4 shares · 59,897 followers View post →
bioRxiv
@biorxivpreprint · X

Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons https://t.co/pY5L1JyLGj #bioRxiv

Oct 29, 2021 · 137,027 followers View post →