PubHawk
Front Aging May 2022 PMID 35821806

A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement), an Orally Administered Supplementation in Middle Aged and Older Adults.

Hao Huang

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Mentions

104
Peak: 55 in Jan 2024
across 3 sources since Mar 2022

Extended reach

672,229
potential audience

Total likes

10,815

Video views

524,664

Mentions per month

Mar 2022 – Jun 2024

Where it's discussed

  • X / Twitter70 posts
  • News21 articles
  • YouTube13 videos

AI synopsis

What people are saying

In the discussions, notable mentions include posts highlighting the increase of NAD levels after 60 days, while others raise concerns about statistical reliability and conflict of interest in the study. Phrases like 'very fishy statistical methods' demonstrate skepticism and contribute to a critical tone, while references to health benefits foster a mix of curiosity and doubt about the supplement's implications.

AgreementNeither agree nor disagree

There is a mixture of skepticism and support, with some discussing benefits while others question the study's validity.

InterestModerate interest

Posts show moderate curiosity about the findings, reflecting some relevance to current health discussions.

EngagementModerate engagement

Conversations reference research details and methods but vary in depth, with some being dismissive.

ImpactModerate impact

Participants perceive the research as having some importance, but skepticism limits the overall perception of impact.

Abstract in brief

  • The study evaluated the effectiveness and safety of Uthever NMN, an anti-aging supplement, in healthy adults aged 40 to 65 through a double-blind, placebo-controlled trial with 66 participants.
  • Results showed a significant increase in NAD/NADH levels in the Uthever group after 30 and 60 days compared to a stable level in the placebo group, indicating a potential anti-aging effect.
  • Additionally, while the Uthever group maintained stable HOMA IR scores, the placebo group experienced a decline, suggesting that Uthever may enhance insulin sensitivity associated with anti-aging benefits.
Read the full abstract

Top posts

Most liked on X and Bluesky
SciTube
@scitube_social · X

#Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https://t.co/nadzV7C6pm). Watch the #animation to find out the results of their #ClinicalTrial: https://t.co/Ib3ECJ4YEw

Jan 11, 2024 · 819 likes · 54 shares · 2,916 followers View post →
Dr Brad Stanfield
@BradStanfieldMD · X

NEW VIDEO - 7th #NMN Human Study Don't be misled https://t.co/lAxJY9axl2 https://t.co/tvLQAGXe7j https://t.co/YxjLYrfYec

May 6, 2022 · 20 likes · 2 shares · 29,392 followers View post →
Matt McAteer
@MatthewMcAteer0 · X

Incredibly misleading paper. 1) Very fishy statistical methods and huge conflict of interest 2) Of course the placebo group had worse insulin sensitivity than the treatment group, because you were giving SUGAR PILLS TO THE PLACEBO GROUP.

May 6, 2022 · 2 likes · 2,668 followers View post →
ふくまる@食から健康を考える
@fukumaru_foody · X

NMN含有量がゼロの製品もあったみたいやけど、 NMN摂取とNAD+の増加を調べた研究では、プラセボ（偽薬）のグループでもNAD+が増えてるから、 NMN含有量がゼロでも効果がゼロってわけでもなさそう？笑 https://t.co/x9er6bneIS https://t.co/vc6gjlfqiP

Nov 2, 2022 · 1 like · 1,258 followers View post →
韭菜盒子
@_jiucaihezi__ · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 14,578 followers View post →
Scientia
@scientia_social · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 11, 2024 · 54 shares · 12,398 followers View post →

All mentions

₿E
@elektrikki · X

Nicotinamide Mononucleotide, abbreviated as NMN, is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), an essential molecule present in all living cells. Tests showed a 38% increase in NAD levels just 60 days after ingestion https://t.co/5mfGU5XFRi

Jun 29, 2024 · 312 followers View post →
افسانه شاهی
@afsaneshahi · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 24, 2024 · 54 shares · 1,050 followers View post →
Joy Esquivel
@JoyEsquive51068 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 23, 2024 · 54 shares View post →
Ergül Çakır
@Ergulcakir42 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 22, 2024 · 54 shares · 75 followers View post →
Самвел Саакян
@Samvel299Samvel · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 22, 2024 · 54 shares View post →
Sophia Ahrend
@Sophia_Ahrend · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 224 followers View post →
迎送花香的风
@swnlng3 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 753 followers View post →
ウルトラマン ファイティング エボリューション
@Donois_Ahrend · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 321 followers View post →
Alexander Shalav
@ShalavAlex · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 644 followers View post →
Aservantof JEHOVAH
@aslaveofJEHOVAH · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 446 followers View post →
Samuelmporton
@samuelmpor62272 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 10 followers View post →
Crypto Princesss
@Emilyweb_3 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 9,775 followers View post →
RedWine
@sansanyi15 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 21, 2024 · 54 shares · 252 followers View post →
Tuan Son
@nosnaut242 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 261 followers View post →
PartnerProfits4
@partnerprofits4 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 54 followers View post →
Andrеw Brоgdan
@brogdannandrew · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 14 followers View post →
Nihon Raibu Chūn
@williamrmb88138 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 9 followers View post →
k pop
@MUSIC_JAPAN57 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 3 followers View post →
Lourdes Luis Bernar
@lourdes_bernar · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 89 followers View post →
Monakhan Khan
@MonakhanKhan10 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 48 followers View post →
GhanaFor4You
@GhanaFor4You · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 20, 2024 · 54 shares · 3,011 followers View post →
Moustapha
@Moustap305 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 2,435 followers View post →
Jason Oliver
@jasonoli123456 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 14 followers View post →
Queen Wolf
@QueenWolf135469 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 99 followers View post →
Шинэ үе
@erduuno1 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 1,201 followers View post →
Bat
@Bat5599 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 1,177 followers View post →
Zubair Ahmed
@Sir_Ahmedo_ · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 1,821 followers View post →
abdul ghafoor
@abdulgh71246219 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 166 followers View post →
RedWine
@sansanyi15 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 252 followers View post →
BEST
@Since_Jeff · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 2,685 followers View post →
Gingla gbo
@GboGingla46656 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 19, 2024 · 54 shares · 65 followers View post →
Chidambara .ML.
@chidambara09 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 11,701 followers View post →
realboy
@realboyemmanuel · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 542 followers View post →
Heros de Moraes
@HerosMoraes · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 8,115 followers View post →
韭菜盒子
@_jiucaihezi__ · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 14,578 followers View post →
Lewis Nancy
@LewisNancy923 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 46 followers View post →
معرفت
@marefat182 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 265 followers View post →
Minardo Rodriguez
@rod731108 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 197 followers View post →
Urtnasan Ts
@UrtnasanT94324 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 25 followers View post →
Paul Peeters
@PaulPeete25 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 18, 2024 · 54 shares · 1,894 followers View post →
ffm_municipio
@ffm_municipio · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 177 followers View post →
Yordy
@Yordy73451849 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 118 followers View post →
Pedro Quispe
@pedroqc36 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 123 followers View post →
THE_KING
@Fola_gbadee · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 2,042 followers View post →
Jpaulzac8
@mariah193290 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 534 followers View post →
Olupot Charles
@OlupotChar78955 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 1,241 followers View post →
Fida Hussain Wattoo
@FidaA79318 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 471 followers View post →
El Pidio Valde
@pidio71313 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 28 followers View post →
nazaret landinez
@LandinezNazare1 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 217 followers View post →
Sandy ✨ み ゆみ
@sd8223932 · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 3 followers View post →
☘️ MURAT DUVARKUŞU ☘️ EST
@muratdvrks · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 2,231 followers View post →
X Fourth Official
@ondari_gideon · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 983 followers View post →
hassan ali
@lonelyguitar · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 17, 2024 · 54 shares · 63 followers View post →
Scientia
@scientia_social · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 11, 2024 · 54 shares · 12,398 followers View post →
Scipod
@scipod_social · X

RT @scitube_social: #Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https:…

Jan 11, 2024 · 54 shares · 6,867 followers View post →
SciTube
@scitube_social · X

#Scientists at #EffePharm in Shanghai assessed the safety & effectiveness of #Uthever, an #antiaging supplement (https://t.co/nadzV7C6pm). Watch the #animation to find out the results of their #ClinicalTrial: https://t.co/Ib3ECJ4YEw

Jan 11, 2024 · 819 likes · 54 shares · 2,916 followers View post →
B3n7ic@
@b3n7ic0 · X

@davidasinclair what do you think about this https://t.co/RUZdt0CR89

Nov 29, 2022 · 248 followers View post →
ふくまる@食から健康を考える
@fukumaru_foody · X

NMN含有量がゼロの製品もあったみたいやけど、 NMN摂取とNAD+の増加を調べた研究では、プラセボ（偽薬）のグループでもNAD+が増えてるから、 NMN含有量がゼロでも効果がゼロってわけでもなさそう？笑 https://t.co/x9er6bneIS https://t.co/vc6gjlfqiP

Nov 2, 2022 · 1 like · 1,258 followers View post →
UndoAge
@udacoffee · X

@Alman95822408 Hey Edwin, great question! There’s lots of work showing that NMN is able to be absorbed when taken orally! One of the big reasons for using NMN at all is that it is absorbed orally and can then be turned into NAD+, whereas NAD+ typically needs to be IV! https://t.co/jewcXir3T3

Oct 20, 2022 · 121 followers View post →
Dr. Todd Ewing PhD
@EwingT_PhD · X

In a placebo-controlled trial of nicotinamide mononucleoside (NMN): At the end of the study, the mean HOMA IR Index showed a rise of 0.6% among the Uthever group and 30.6% among the Placebo group from baseline. Weird effect in placebo group @ 60 days.

Jun 2, 2022 · 3,605 followers View post →
Moises Hernandez MD
@drmoyhv · X

Frontiers | A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of NMN https://t.co/pjuFaM5Ws1

May 8, 2022 · 95 followers View post →
Katie Smith
@KatieSm73640241 · X

RT @BradStanfieldMD: NEW VIDEO - 7th #NMN Human Study Don't be misled https://t.co/lAxJY9axl2 https://t.co/tvLQAGXe7j https://t.co/YxjL…

May 6, 2022 · 2 shares · 126 followers View post →
Matt McAteer
@MatthewMcAteer0 · X

Incredibly misleading paper. 1) Very fishy statistical methods and huge conflict of interest 2) Of course the placebo group had worse insulin sensitivity than the treatment group, because you were giving SUGAR PILLS TO THE PLACEBO GROUP.

May 6, 2022 · 2 likes · 2,668 followers View post →
Mesha
@cosmautic · X

RT @BradStanfieldMD: NEW VIDEO - 7th #NMN Human Study Don't be misled https://t.co/lAxJY9axl2 https://t.co/tvLQAGXe7j https://t.co/YxjL…

May 6, 2022 · 2 shares · 461 followers View post →
Dr Brad Stanfield
@BradStanfieldMD · X

NEW VIDEO - 7th #NMN Human Study Don't be misled https://t.co/lAxJY9axl2 https://t.co/tvLQAGXe7j https://t.co/YxjLYrfYec

May 6, 2022 · 20 likes · 2 shares · 29,392 followers View post →
Longevity Global
@LongevityGL · X

RT @FrontAging: New Research: A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy a…

May 5, 2022 · 1 share · 3,209 followers View post →
Frontiers - Aging
@FrontAging · X

New Research: A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement), an Orally Administered Supplementation in Middle Aged and Older Adults https://t.co/ZCMPHeS2Gl #Aging

May 5, 2022 · 1 share · 1,710 followers View post →
QueenBioInvestor
@QueenBioInvest · X

@mjoh090 @CharlesMBrenner Have a look at this new published article https://t.co/7BMXRTbKJ4

Mar 25, 2022 · 293 followers View post →
ProHealth
@ProHealth · X

New ProHealth Uthever NMN clinical study results! "A Multicentre, Randomized, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement)..." https://t.co/GnEGbqTtd3 https://t.co/XYbencdz8E

Mar 24, 2022 · 3,175 followers View post →
ProHealth Longevity
@PHLongevity · X

New ProHealth Uthever NMN clinical study results! "A Multicentre, Randomized, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement)..." https://t.co/xm519Nwoob https://t.co/K2FaHSK6Pz

Mar 24, 2022 · 209 followers View post →