Front Endocrinol (Lausanne) August 2022 PMID 35937836

Efficacy of flavonoids-containing supplements on insulin resistance and associated metabolic risk factors in overweight and obese subjects: a systematic review and meta-analysis of 25 randomized controlled trials.

Jia Yao, Yuan Zhang, Jia Zhao, Xian-Zhe Wang, Yu-Ping Lin, Lu Sun, Qi-Yun Lu, Guan-Jie Fan

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Mentions

4
Peak: 3 in Aug 2024
across 2 sources since Aug 2024

Extended reach

18,611
potential audience

Total likes

1

Video views

80

Mentions per month

Aug 2024 – Sep 2025

Where it's discussed

  • YouTube3 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The overall tone is cautiously optimistic, with discussions emphasizing the metabolic benefits demonstrated by the research, such as improvements in insulin sensitivity and cholesterol levels, using words like 'promising', 'positive', and 'significant'. The inclusion of references to multiple studies and details about trial outcomes reflect a moderate level of engagement, highlighting the relevance and potential impact of the findings on health practices.

AgreementModerate agreement

Most discussions acknowledge the positive findings regarding flavonoids and insulin resistance, supported by phrases like 'significant benefits' and 'promising results'.

InterestHigh interest

Participants show high interest, often referencing the potential health benefits and implications for obesity management, reflected in enthusiastic language like 'exciting', 'potentially groundbreaking', and 'worth considering'.

EngagementModerate engagement

Several social discussions delve into methodological details, citing specific outcomes such as reductions in HOMA-IR and improvements in metabolic risk factors, indicating moderate of deep engagement.

ImpactModerate impact

The tone suggests that many believe this research could influence future dietary supplement recommendations or clinical practices, described as 'important stepping stone' or 'could pave the way for new treatments'.

Abstract in brief

  • * The analysis included 25 randomized controlled trials (RCTs) with nearly 2,000 participants, revealing significant reductions in HOMA-IR (a measure of insulin sensitivity) for those taking flavonoid supplements, especially those with mixed flavonoids.
  • * Secondary outcomes showed that other metabolic factors like fasting blood glucose, cholesterol, and body weight were also positively affected by flavonoid supplements without notable adverse effects.

Top posts

Most liked on X and Bluesky
The Institute for Functional Medicine (IFM)
@fxmed · X

* References: doi:10.1093/advances/nmaa010 doi:10.1080/01635581.2024.2417457 doi:10.1186/s12937-022-00778-w doi:10.3389/fendo.2022.917692 doi:10.1016/j.ctim.2022.102865 doi:10.1002/mnfr.202100976

Sep 9, 2025 · 18,532 followers View post →

All mentions

The Institute for Functional Medicine (IFM)
@fxmed · X

* References: doi:10.1093/advances/nmaa010 doi:10.1080/01635581.2024.2417457 doi:10.1186/s12937-022-00778-w doi:10.3389/fendo.2022.917692 doi:10.1016/j.ctim.2022.102865 doi:10.1002/mnfr.202100976

Sep 9, 2025 · 18,532 followers View post →