PubHawk
Hypertension October 2022 PMID 35968698

High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients.

Valentina Trimarco, Raffaele Izzo, Carmine Morisco, Pasquale Mone, Maria Virginia Manzi, Angela Falco, Daniela Pacella, Paola Gallo, Maria Lembo, Gaetano Santulli, Bruno Trimarco

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Mentions

51
Peak: 20 in May 2023
across 3 sources since Aug 2022

Extended reach

281,295
potential audience

Total likes

1,853

Video views

41,838

Mentions per month

Aug 2022 – Jun 2025

Where it's discussed

  • X / Twitter43 posts
  • News6 articles
  • YouTube2 videos

AI synopsis

What people are saying

The digital discussions highlight a shift in perception about HDL cholesterol, with phrases like 'raises disease risk' and 'U-shaped association' emphasizing the nuanced understanding of HDL's role. The tone and choice of words reflect curiosity and validation of the study's findings, indicating that this publication might alter mainstream views on cholesterol management.

AgreementModerate agreement

Most discussions support the idea that high HDL levels may pose risks, especially in hypertensive males, aligning with the study's findings.

InterestModerate interest

Comments show moderate curiosity, with many focusing on the surprising nature of HDL being harmful rather than beneficial.

EngagementModerate engagement

Participants reference specific data points, such as the U-shaped relationship and HDL thresholds, indicating moderate engagement.

ImpactModerate impact

The discussions suggest the article could influence how clinicians evaluate cholesterol, signaling a notable, though not revolutionary, impact.

Abstract in brief

  • Elevated levels of HDL cholesterol are linked to increased cardiovascular risk, especially in hypertensive male patients.
  • The study found a U-shaped relationship between HDL levels and cardiovascular events, meaning both very low and very high HDL levels are associated with higher risks.
  • In female patients, high HDL levels did not show the same increased risk, indicating a gender difference in how HDL impacts cardiovascular health in hypertensive individuals.
Read the full abstract

Top posts

Most liked on X and Bluesky
Gorka Orive
@gorka_orive · X

Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encima de 80 mg/dl. Incluso niveles altos de HDL se asocian con mayor riesgo de fracturas óseas. https://t.co/7eqdMAM0g6

May 19, 2023 · 51 likes · 15 shares · 115,745 followers View post →
Hypertension
@HyperAHA · X

High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 22 likes · 7 shares · 10,768 followers View post →
Hypertension
@HyperAHA · X

ON THE COVER: High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQrZpb https://t.co/WAOA2wJLlG

Sep 20, 2022 · 13 likes · 3 shares · 10,768 followers View post →
LipoFan
@lipo_fan · X

High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/2Xnqu25107

Mar 15, 2023 · 11 likes · 2,991 followers View post →
Teresa Gijon Conde
@TGijonConde · X

There is a U-shaped association between HDL-C and the risk of cardiovascular events in male patients with hypertension. High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients @SEHLELHA140_90 @AMAREVA_Madrid https://t.co/HY8uLh8STl

Nov 22, 2022 · 9 likes · 2 shares · 1,054 followers View post →
Dr. Eddie Ramirez
@EddieRDMD · X

Journal Hypertension: Too Much ‘Good’ Cholesterol Can Harm the Heart HDL cholesterol raises disease risk at levels above 80 milligrams per deciliter Journal: https://t.co/PGDKOaq5UU Press: https://t.co/KeeGezrBnd @ToshiyukiHorie https://t.co/nH5gdUb2Bl

May 21, 2023 · 6 likes · 1 share · 4,787 followers View post →

All mentions

Lee Stevenson
@bashuser · X

It isn't the cholesterol and science just isn't getting it. Since they have shown LDL is not what causes cardiovascular disease now they are blaming HDL. They cannot get away from the flawed cholesterol science to see the whole picture. https://t.co/JZQOTeNckE

May 27, 2024 · 1 like · 1,706 followers View post →
williams diaz
@williamsdiaz58 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 28, 2023 · 15 shares · 1,040 followers View post →
ysaito
@ysaito8015 · X

RT @EddieRDMD: Journal Hypertension: Too Much ‘Good’ Cholesterol Can Harm the Heart HDL cholesterol raises disease risk at levels above 80…

May 21, 2023 · 1 share · 2,765 followers View post →
Toshiyuki Horie｜堀江 俊之
@ToshiyukiHorie · X

RT @EddieRDMD: Journal Hypertension: Too Much ‘Good’ Cholesterol Can Harm the Heart HDL cholesterol raises disease risk at levels above 80…

May 21, 2023 · 1 share · 25,197 followers View post →
Maria Antonieta
@mantonieta50 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 21, 2023 · 15 shares · 1,253 followers View post →
@nnie
@anu_acevedo · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 21, 2023 · 15 shares · 14 followers View post →
Dr. Eddie Ramirez
@EddieRDMD · X

Journal Hypertension: Too Much ‘Good’ Cholesterol Can Harm the Heart HDL cholesterol raises disease risk at levels above 80 milligrams per deciliter Journal: https://t.co/PGDKOaq5UU Press: https://t.co/KeeGezrBnd @ToshiyukiHorie https://t.co/nH5gdUb2Bl

May 21, 2023 · 6 likes · 1 share · 4,787 followers View post →
Antonio Palomar
@GarcPalomar · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 21, 2023 · 15 shares · 4,185 followers View post →
sol
@solfarmarural · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 21, 2023 · 15 shares · 252 followers View post →
marcia
@marcivirgo · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 20, 2023 · 15 shares · 418 followers View post →
Ricard Beltran
@RicardBeltran1 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 20, 2023 · 15 shares · 123 followers View post →
Ruben Dario Aguirre MD
@Rubencho80 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 267 followers View post →
ana leon
@anitals2009 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 693 followers View post →
Mari Carmen Porres
@LaPorres · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 10,668 followers View post →
Alicia León
@leonalicia8 · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 48 followers View post →
Rafa Vázquez #SinCienciaNoHayFuturo
@monkeyplatillos · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 1,565 followers View post →
Wimen
@1a31551c566e43d · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 670 followers View post →
BEATRIZ RIBALLO
@beatrizriballo · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 184 followers View post →
mirta tapia
@dratapia · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 115 followers View post →
Elvissss
@ev_eza · X

RT @gorka_orive: Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encim…

May 19, 2023 · 15 shares · 508 followers View post →
Gorka Orive
@gorka_orive · X

Otro estudio en 11.000 personas con hipertensión observó mayor mortalidad en aquellos con niveles por debajo de 40 o encima de 80 mg/dl. Incluso niveles altos de HDL se asocian con mayor riesgo de fracturas óseas. https://t.co/7eqdMAM0g6

May 19, 2023 · 51 likes · 15 shares · 115,745 followers View post →
LipoFan
@lipo_fan · X

High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/2Xnqu25107

Mar 15, 2023 · 11 likes · 2,991 followers View post →
SEH-LELHA
@SEHLELHA140_90 · X

RT @TGijonConde: There is a U-shaped association between HDL-C and the risk of cardiovascular events in male patients with hypertension. Hi…

Nov 22, 2022 · 2 shares · 5,835 followers View post →
AMAREVA Riesgo Vascular
@AMAREVA_Madrid · X

RT @TGijonConde: There is a U-shaped association between HDL-C and the risk of cardiovascular events in male patients with hypertension. Hi…

Nov 22, 2022 · 2 shares · 381 followers View post →
Teresa Gijon Conde
@TGijonConde · X

There is a U-shaped association between HDL-C and the risk of cardiovascular events in male patients with hypertension. High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients @SEHLELHA140_90 @AMAREVA_Madrid https://t.co/HY8uLh8STl

Nov 22, 2022 · 9 likes · 2 shares · 1,054 followers View post →
Sean C. Lucan, MD
@SeanLucan · X

"Good cholesterol?" (not really "cholesterol" and maybe not really "good") https://t.co/juIBgkGkxH via @HyperAHA #lipids #HDL #cardiovascular #health https://t.co/cdTIbIxHYo

Oct 21, 2022 · 1 like · 1,498 followers View post →
Kidney in Cardiovascular Disease
@KidneyInCVD · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 29, 2022 · 7 shares · 1,916 followers View post →
Dr Anastasia Mihailidou FAHA FCSANZ FESC
@AnastasiaSMihai · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 28, 2022 · 7 shares · 19,309 followers View post →
ASEMEVE
@asemeve · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 28, 2022 · 7 shares · 476 followers View post →
Nicolas Renna, MD PhD ISHF FESC
@nicolasrennamd · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 7 shares · 934 followers View post →
日本高血圧学会（公式）
@JSHypertension · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 7 shares · 3,363 followers View post →
Christián
@Christi07697214 · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 7 shares · 257 followers View post →
Mayela HJ
@MAYELAHJ · X

RT @HyperAHA: High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 7 shares · 210 followers View post →
Hypertension
@HyperAHA · X

High HDL Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQsxeJ https://t.co/UtaBCGUOhL

Sep 27, 2022 · 22 likes · 7 shares · 10,768 followers View post →
ASEMEVE
@asemeve · X

RT @HyperAHA: ON THE COVER: High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https:/…

Sep 21, 2022 · 3 shares · 476 followers View post →
roberto flores
@arobertoflores · X

RT @HyperAHA: ON THE COVER: High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https:/…

Sep 20, 2022 · 3 shares · 152 followers View post →
Hypertension
@HyperAHA · X

ON THE COVER: High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/VxTXiQrZpb https://t.co/WAOA2wJLlG

Sep 20, 2022 · 13 likes · 3 shares · 10,768 followers View post →
@investigando
@rocatanho · X

Hay una asociación en forma de U entre las HDL y el riesgo de eventos CV en los pacientes hipertensos masculinos #HDL #CV https://t.co/IT1bY2DAS5

Aug 23, 2022 · 1 like · 400 followers View post →
CH Chiang MD, MPH, PhD
@CHChiang9 · X

High HDL (High-Density Lipoprotein) Cholesterol Increases Cardiovascular Risk in Hypertensive Patients https://t.co/QsWGwGswnQ https://t.co/D5vpt6Gj5g

Aug 22, 2022 · 1 like · 12 followers View post →
Hiromichi Miyashita, MD, ABFM, OMD
@MiyashitaMD · X

? U-shaped HDL-C of impacting on cardiovascular

Aug 21, 2022 · 1 like · 111 followers View post →
ふたば
@6bMDWgyEEVqdMsC · X

RT @Office_j: ただし性別に検討すると、U字現象は男性のみ。 https://t.co/dnoEmjeIMy

Aug 16, 2022 · 2 shares · 447 followers View post →
1型の人生
@osmobox · X

RT @Office_j: ただし性別に検討すると、U字現象は男性のみ。 https://t.co/dnoEmjeIMy

Aug 16, 2022 · 2 shares · 314 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

ただし性別に検討すると、U字現象は男性のみ。 https://t.co/dnoEmjeIMy

Aug 16, 2022 · 1 like · 2 shares · 4,912 followers View post →