J Clin Invest August 2022 PMID 35968789

Metabolic changes in aging humans: current evidence and therapeutic strategies.

Allyson K Palmer, Michael D Jensen

Mentions

122
Peak: 92 in Sep 2022
across 4 sources since Aug 2022

Extended reach

608,603
potential audience

Total likes

1,405

Video views

45,998

Mentions per month

Aug 2022 – Dec 2025

Where it's discussed

  • X / Twitter99 posts
  • Instagram15 posts
  • News6 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reveal a positive consensus on the importance of lifestyle interventions like exercise and diet, with phrases like 'best proven way' and 'new research,' which underscore the significance and practical relevance of the article’s insights. The tone reflects both appreciation and a desire to apply these strategies in aging health management.

AgreementModerate agreement

Most discussions acknowledge and support the core conclusions of the article, emphasizing the importance of physical activity and nutrition in managing metabolic changes with age.

InterestHigh interest

Posts demonstrate high interest by highlighting specific strategies such as exercise, diet, and the relevance of the research, indicating enthusiasm for the topic.

EngagementModerate engagement

Posts include references to detailed content like fat, muscle, and liver metabolism, suggesting moderate to deep engagement through sharing insights and summaries.

ImpactModerate impact

Discussions suggest these findings are viewed as valuable for advancing aging health strategies, though mostly within an academic or health-conscious context, indicating moderate impact.

Abstract in brief

  • Aging is closely connected to changes in metabolism, such as increased fat around the abdomen and loss of muscle mass, which are influenced by fundamental aging processes.
  • These metabolic changes are worsened by a sedentary lifestyle but can be partly prevented through regular physical activity and targeted interventions.
  • The text reviews how aging affects key metabolic tissues like fat, muscle, and liver, and discusses potential therapies—including caloric restriction, exercise, and drugs targeting aging cells—based on current human research.]

Top posts

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Satchin Panda
@SatchinPanda · X

Timely @jclinicalinvest review on metabolic changes in aging humans with specific focus on fat, muscle and liver. Take home message - the best and proven way to slow down aging is optimum nutrition and exercise. https://t.co/wbgiKaYod5 https://t.co/UxoCzB8iGv

Sep 11, 2022 · 244 likes · 73 shares · 52,521 followers View post →
Agingdoc
@agingdoc1 · X

Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/45Vo042nsA https://t.co/lkjsihDE6c

Sep 12, 2022 · 22 likes · 7 shares · 45,109 followers View post →
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

#starzenie #ćwiczenia #omega3 #Okinawa JCI - Zmiany metaboliczne u starzejących się ludzi: aktualne dowody i strategie terapeutyczne https://t.co/M31jGoW2tC

Sep 12, 2022 · 4 likes · 1 share · 3,467 followers View post →
та самая допиздержка
@dopizderzhka · X

@gelificenta @Johanna_fromAir (c) сказала некая твиттерская. Послушаем же ученых https://t.co/9vxoJdpHXm

Sep 28, 2023 · 3 likes · 1,956 followers View post →
Adipose Papers
@adipose_papers · X

Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/CanH541OvY https://t.co/dHLNhNAQYS

Aug 15, 2022 · 2 likes · 1 share · 2,484 followers View post →
WHO Collaborating Center for Frailty
@WHOCenterFrailt · X

Maintenance of activity with aging ? in "Metabolic changes in aging humans: current evidence and therapeutic strategies" https://t.co/mQ9Xsj7V9E @brunovellas @RollandYves2 @drjohnmorley @SoutoPhilipe @JuanluSanchez5 @aragonijaqui

Sep 13, 2022 · 1 like · 3,209 followers View post →

All mentions

та самая допиздержка
@dopizderzhka · X

@gelificenta @Johanna_fromAir (c) сказала некая твиттерская. Послушаем же ученых https://t.co/9vxoJdpHXm

Sep 28, 2023 · 3 likes · 1,956 followers View post →
#ThankYouCena
@lifeofpkay_ · X

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Sep 2, 2023 · 1 like · 1,988 followers View post →
anonymoushater
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Jun 28, 2023 · 145 followers View post →
Ovais Shafi
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Let's Prolong Life
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Sep 14, 2022 · 7 shares · 8 followers View post →
Mathieu Maltais
@mathieu_maltais · X

RT @CentreOMSfragil: Maintenir des activités avec l'âge ? dans "Metabolic changes in aging humans: current evidence and therapeutic strateg…

Sep 13, 2022 · 1 share · 268 followers View post →
OMS Centre Collaborateur pour la Fragilité
@CentreOMSfragil · X

Maintenir des activités avec l'âge ? dans "Metabolic changes in aging humans: current evidence and therapeutic strategies" https://t.co/nG8sjyNrlm @brunovellas @m_aubertin @mathieu_maltais @macesari @FNourhashemi

Sep 13, 2022 · 1 like · 1 share · 576 followers View post →
WHO Collaborating Center for Frailty
@WHOCenterFrailt · X

Maintenance of activity with aging ? in "Metabolic changes in aging humans: current evidence and therapeutic strategies" https://t.co/mQ9Xsj7V9E @brunovellas @RollandYves2 @drjohnmorley @SoutoPhilipe @JuanluSanchez5 @aragonijaqui

Sep 13, 2022 · 1 like · 3,209 followers View post →
Derhsing Lai, Ph.D
@DserhsingLai · X

人類老化的代謝改變:目前的証據和醫療的策略 Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/AgWSeWUQ1j

Sep 13, 2022 · 150 followers View post →
Daniel Vera
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Nutrióloga Clínica Magaly Lizaola
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Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

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Sep 12, 2022 · 2,236 followers View post →
PC ⛓
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これ以外
@jafer_rashad · X

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Adipose Tissue: The Circadian clock of Metabolism
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Derhsing Lai, Ph.D
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JCI - Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/KBNoeemTrn

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Viviana
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Mind Your Science!
@MindYourSci · X

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jebus christoff
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Agingdoc
@agingdoc1 · X

Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/45Vo042nsA https://t.co/lkjsihDE6c

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Hec
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Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

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Mind Your Science!
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Satchin Panda
@SatchinPanda · X

Timely @jclinicalinvest review on metabolic changes in aging humans with specific focus on fat, muscle and liver. Take home message - the best and proven way to slow down aging is optimum nutrition and exercise. https://t.co/wbgiKaYod5 https://t.co/UxoCzB8iGv

Sep 11, 2022 · 244 likes · 73 shares · 52,521 followers View post →
Let's Prolong Life
@hunt4longevity · X

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Adipose Papers
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Metabolic changes in aging humans: current evidence and therapeutic strategies https://t.co/CanH541OvY https://t.co/dHLNhNAQYS

Aug 15, 2022 · 2 likes · 1 share · 2,484 followers View post →
The Average Weight for Women Based on Age and Height
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doi:10.1172/JCI158451. Turesson A, De Souto Barreto P, Nydahl M, Koochek A. The relationship between physical activity and appetite among older adults - A ...

Dec 31, 2025 View →
Bài 5 | PDF
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doi: 10.1172/JCI158451. PMID: 35968789; PMCID: PMC9374375. 11. Nutricare. Người già bị tiêu chảy nên ăn gì? 5 loại thực phẩm giúp nhanh khỏe, lấy lại sức.

Dec 31, 2025 View →
Obes in Elderly 1 | PDF | Adipose Tissue | Obesity
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doi: 10.1172/JCI158451. PMID: 35968789; PMCID: PMC9374375. Figure 2. Cellular changes in adipose and skeletal muscle with aging1. In adipose tissue, aged ...

Dec 31, 2025 View →
Você já ouviu dizer que “o metabolismo fica mais lento com o tempo ...
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doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14 · treinoemcasacomcida's profile ...

Dec 12, 2025 View →
Você não está engordando “porque sim”. Não é idade. Não é ...
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doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14 · Sign up • Instagram · Meta.

Dec 11, 2025 View →
Fernanda Rodrigues | Alimentação Pós-40: Os Pilares da Saúde ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14.

Dec 9, 2025 View →
Com a chegada da menopausa o metabolismo fica mais lento, por ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14.

Dec 5, 2025 View →
Nem sempre o problema é o metabolismo “lento”. Muitas vezes, é ...
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J Clin Invest. 2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March ...

Nov 26, 2025 View →
Você já ouviu falar em metabolaging? É o termo que descreve como ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14 · dr ...

Nov 12, 2025 View →
Atenção, 40+! O tempo passa, e o metabolismo muda. Você tem ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14.

Oct 21, 2025 View →
Nem sempre é falta de tempo, muitas vezes é falta de organização e ...
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DOI: https://doi.org/10.1172/JCI158451. #metabolismo #metabolismoacelerado #estilodevida #nutrição #praticabaseadaemevidencias. more. View all ...

Sep 17, 2025 View →
Você sente que, mesmo se esforçando na alimentação e nos ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14.

Aug 25, 2025 View →
Não estou aqui só pra te ensinar a montar um prato. Mas também ...
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DOI: https://doi.org/10.1172/JCI158451. #metabolismo #metabolismoacelerado #estilodevida #nutrição #praticabaseadaemevidencias. more. July 31.

Aug 6, 2025 View →
Você já percebeu que, com o passar dos anos, fica mais difícil ...
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J Clin Invest. 2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March ...

Jul 17, 2025 View →
Na Terceira idade muitos pacientes se queixam de que estão ...
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J Clin Invest. 2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March ...

Jul 15, 2025 View →
Controlar o peso após os 60 anos vai muito além de "comer menos ...
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doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14 · dra.amandapormann's profile ...

Jul 3, 2025 View →
Você achava que o metabolismo já começava a cair aos 30 ou 40 ...
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2022;132(16):e158451. doi:10.1172/JCI158451 #nutrição #metabolismolento #alimentaçãosaudavel. more. View all 10 comments. March 14.

Jun 27, 2025 View →
How Many Steps Do You Need To Walk Daily To Lose Weight?
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doi:10.1172/JCI158451. Rezuş E, Burlui A, Cardoneanu A, et al. Inactivity and skeletal muscle metabolism: A vicious cycle in old age. Int J ...

Apr 23, 2025 View →
WCR 19-03-2025 | PDF | Body Shape
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J Clin Invest 132, e158451, doi:10.1172/JCI158451. 381 4. Ransdell, L.B.; Wayment, H.A.; Lopez, N.; Lorts, C.; Schwartz, A.L.; Pugliesi, K ...

Mar 19, 2025 View →
抗衰新利器:全国首家精准测衰服务,助你全面掌握自身衰老状态_检测
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doi: 10.1172/JCI158451. PMID: 35968789; PMCID: PMC9374375. [2]Ferrucci, L., Fabbri, E. Inflammageing: chronic inflammation in ageing ...

Jun 1, 2023 View →
descabelada - Instagram
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DOI: https://doi.org/10.1172/JCI158451. #metabolismo #metabolismoacelerado #estilodevida #nutrição #praticabaseadaemevidencias. more. View all ...

Aug 8, 2021 View →