The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demonstrating technical aspects of the methods described. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/yGjkagrMcG
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.
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AI synopsis
What people are saying
The discussions surrounding the publication reflect a mix of excitement and concern about synthetic embryos. For instance, one user noted that the ability to create embryos without traditional biological components could revolutionize reproduction, citing that it is something even Aldous Huxley couldn't have imagined. Posts include phrases like 'game changer' and 'amazing work', indicating enthusiasm, while other users discussed practical implications and concerns, which collectively demonstrate the depth of interest and the nuanced views present in the conversations.
The majority of discussions express a supportive view of the research findings, highlighting innovative aspects and potential applications.
There is a strong curiosity reflected in the posts, with many users expressing a fascination with the concept of synthetic embryos and their developments.
Several discussions delve into technical aspects and implications of the research, though not all show deep engagement with complex scientific details.
Many users perceive this research as having a significant impact on future reproductive technologies and scientific understanding.
Abstract in brief
- Researchers developed synthetic embryos (sEmbryos) from mouse naive embryonic stem cells (ESCs) that contain both embryonic and extraembryonic structures.
- By coaggregating nontransduced ESCs with ESCs expressing specific genes (Cdx2 and Gata4), they were able to guide the development towards essential cell lineages.
- These sEmbryos achieved significant developmental milestones, including gastrulation and organ progenitor formation, demonstrating the potential of naive pluripotent cells to recreate complex mammalian embryonic structures beyond early developmental stages.
Top posts
Most liked on X and BlueskyWe are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs” https://t.co/NI5gKKIAag https://t.co/B8SITBTdhl
We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs” https://t.co/NI5gKKI2kI https://t.co/Y9X7IsIRvL
In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/u05gXn4CAq
Amazing work with exowombs: "Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/wcHD72UtYb
All mentions
Synthetic Embryos from Mouse Naive ESCs: Developmental Insights
Researchers developed synthetic embryos (sEmbryos) from mouse naive embryonic stem cells. These sEmbryos achieved significant developmental milestones, including gastrulation and organ progenitor formation, showcasing…
Hodowanie ludzkich embrionów, powstawanie piorunów oraz wpływ kawy i bezsenności na psychikę - #042
Innovations in Synthetic Embryos: Advancing Developmental Biology
In this episode, Dr. Tarazi reveals insights into synthetic embryos made from embryonic stem cells (ESCs). The study demonstrates how naive ESCs can form complex structures, achieving gastrulation and key developmental…
2/n a)We previously made mouse SEMs solely from naive PSCs (nPSCs), by use of transgenes to separately induce TE & PrE (Tarazi et al. 2022, https://t.co/7S33eteKC6) b)However, we could make human SEMs from naive PSCs without transgenes (Oldak et al. 2023 https://t.co/wQznEHVmPv)? https://t.co/T8L1JLyjvA
@BakulaDaniela @ScheibyeKnudsen @koebenhavns_uni @biogerontology @InSilicoMeds @gladyshev_lab @jacob_hanna that undergo gastrulation and develop organ progenitors (https://t.co/F7LiU5QtQV).
・Post-gastrulation synthetic embryos generated exutero from mouse naive ESCs https://t.co/GOaFw3E8wI
1st synthetic mouse embryos — complete with beating hearts and brains — created with no sperm, eggs or womb https://t.co/kWL8RuREsw ¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/t18skUmc3C
@tazgezwitscher Zukünftig wird man weder Eizellen einer Frau, noch einen Uterus benötigen, wenn Kinderwunsch bei einem Paar besteht. Einfach synthetisieren lassen. Das hätte sich nichtmals Aldous Huxley träumen lassen. https://t.co/Msc80N6Lw7
#STEMCELL Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/wrN0PrHS6T
RT @CellPressNews: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs - check out this research from @jacob_hanna…
RT @CellPressNews: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs - check out this research from @jacob_hanna…
RT @CellPressNews: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs - check out this research from @jacob_hanna…
RT @CellPressNews: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs - check out this research from @jacob_hanna…
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs - check out this research from @jacob_hanna, @noashefi, @Itaymaza, @AlejandroAgCa & others in @CellCellPress #ISSCR23 https://t.co/KcjYnxB1tR
RT @jacob_hanna: 12/n Background - Tarazi et al. Cell 2022 we put a special effort to be able to make all embryonic and extra-embryonic lin…
12/n Background - Tarazi et al. Cell 2022 we put a special effort to be able to make all embryonic and extra-embryonic lineages only from naive PSCs, since in humans authentic TSC and PRE lines cannot be stabilized or derived from embryonic material... https://t.co/55L8yFMATi
@pknoepfler @jacobkimmel Great idea! Would love to see a cartoon & corresponding paper of everyone’s favorite. I’ll go first: https://t.co/CkqShdQv6O
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation sy…
We are pleased to bring you the @CellCellPress paper of #FacesOfCell Shadi Tarazi (@Shadi_Tarazi), “Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs” https://t.co/NI5gKKI2kI https://t.co/Y9X7IsIRvL
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Carine Joubran (@carinejoubran), “Post-gastrulation…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Carine Joubran (@carinejoubran), “Post-gastrulation…
We are pleased to bring you the @CellCellPress paper of #FacesOfCell Carine Joubran (@carinejoubran), “Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs” https://t.co/NI5gKKIAag https://t.co/He2LiRt1vW
….and in the most discussed one, just @1% , all w/great phenotypic variability, which for now limits their use in research (see related work https://t.co/W0nIaXOZ3A for comments on limitations and uses).
Le but est de développer des modèles embryoïdes pour se passer d'embryon animaux/humains en recherche https://t.co/ujGrn7Dniy
"Artificial Wombs - Something Revolutionary or Tech Bro Dream?" Featuring recent work of @alejandroagca on synthetic embryos (sEmbryos) > https://t.co/6is6nD60Ow Spinoffs: @ExoGenesis23, Renewal Bio (@jacob_hanna), Juno (Guid Oei) Other authors: https://t.co/eZ50LoK0Pz
RT @NikoMcCarty: 6. "Synthetic embryos" Two groups @Caltech & @WeizmannScience used mouse stem cells to make “embryo-like structures” w/ w…
6. "Synthetic embryos" Two groups @Caltech & @WeizmannScience used mouse stem cells to make “embryo-like structures” w/ working intestines, beating heart, and start of a brain — no sperm or eggs required. https://t.co/s2Ol9RGeSA
今週の論文 https://t.co/q2R4jNlnJC
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post…
RT @CellCellPress: We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post…
We are pleased to bring you the @CellCellPress paper of #FacesOfCell Alejandro Aguilera Castejon (@AlejandroAgCa), “Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs” https://t.co/NI5gKKIAag https://t.co/B8SITBTdhl
Researchers from @WeizmannScience have enabled the self-assembly of advanced synthetic embryos #sEmbryos in an ex utero setup that underwent organogenesis. Check out this fascinating work @CellCellPress https://t.co/I7K6cGw83K https://t.co/MXtZNATkpG
@Perestupinya https://t.co/8EzlZpsXBZ and https://t.co/18MCCwpU8g
RRIDs were included in the Cell paper "¬Post-Gastrulation Synthetic Embryos Generated Ex…" (https://t.co/R9gHDtNysq). RRIDs like this improve reproducibility in scientific research. #reproducibility #STMpublishing
RT @yamagatm3: Mouse embryos grown without eggs or sperm: why and what’s next? https://t.co/PgOFXMYEPf https://t.co/CRSkZfN3GF https://t.c…
Oh mama... Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/9otg0mElE4
https://t.co/5UWA1OUBjh Speaking with Shadi Tarazi, Serena Michaels, and Joyce Waterhouse https://t.co/7tKTXlM7b9
https://t.co/Dy7dObW1Ii Speaking with Shadi Tarazi and Serena Michaels https://t.co/QgY2aZe6Ph
@ScienceSociety8 @wonderactionv @SerenaM17009865 @frankschoschka @Clubhouse https://t.co/Dy7dObW1Ii
RT @DNA_Nanotech: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/vDGhoRDyeD https://t.co/2oR38ir…
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/vDGhoRDyeD https://t.co/2oR38irhT1
The paper in Cell being discussed and highlighted on the Sep. 1, 2022 cover. "Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs". Tarazi, et. al. https://t.co/aU9sUFmaQZ
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
RT @DrImranSheikh: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/2UwW9hLOqv https://t.co/gSoLHL…
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/2UwW9hLOqv https://t.co/gSoLHLZ0vL
my mind will explode
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
RT @CellCellPress: In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
In the latest issue! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/qrBTFPrS92
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/iqz6dAr7Hg
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs: Cell https://t.co/Ur0qdvlGnF
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
RT @takatoh_life: 【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulatio…
【参考文献】 Synthetic embryos complete gastrulation to neurulation and organogenesis https://t.co/tjNmg7Gi7k Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/u05gXn4CAq
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/NgyDEN0QTH
RT @yamagatm3: Mouse embryos grown without eggs or sperm: why and what’s next? https://t.co/PgOFXMYEPf https://t.co/CRSkZfN3GF https://t.c…
Congratulations! Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs: Cell - we need 3 more days to see the lung!
The paper in "Cell" cited & linked to in the above "Nature" article: “Post-gastrulation synthetic embryos generated 'ex utero' from mouse naive ESCs” https://t.co/pRaBXeH7qb
Jacob Hanna lab Cell. 2022 Aug 2;S0092-8674(22)00981-3. doi: 10.1016/j.cell.2022.07.028. Online ahead of print. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs Shadi Tarazi 1, Alejandro Aguilera-Castrejon 2, Carine Joubran 3,…https://t.co/uP5vWKQrB8
RT @Magda_Skipper: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/xIRJ75loQk @CellCellPress
RT @Magda_Skipper: Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/xIRJ75loQk @CellCellPress
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/xIRJ75loQk @CellCellPress
Mouse embryos grown without eggs or sperm: why and what’s next? https://t.co/PgOFXMYEPf https://t.co/CRSkZfN3GF https://t.co/zK6swUjdDh 胚は8.5日間成長し、心臓、腸管、神経ヒダなど、はっきりとした器官ができた。#日本神経科学学会ニューロナビゲータ
What a great paper! It can change the world. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs: Cell https://t.co/oZeLAEgk8M
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs #FirstSyntheticEmbryos https://t.co/itf1rABWIN
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/24qwKT4xLT
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: 15/n The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos…
RT @jacob_hanna: 15/n The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
RT @jacob_hanna: The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demon…
15/n The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demonstrating technical aspects of methods described. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/yGjkagrMcG
The proofed version of our recent @CellCellPress paper has been made available online with all supplementary videos demonstrating technical aspects of the methods described. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs https://t.co/yGjkagrMcG
RT @CellCellPress: Now online! ¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/xp2it31AZp
¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/cpOL1OJ1Yd
Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/cyALwXpSgK - impressive work to get embryos to develop this far in vitro!
¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs: Cell https://t.co/tHaMFJQhKw
RT @mason_lab: Amazing work with exowombs: "Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/wcHD…
魏茨曼科学研究所的干细胞生物学家Jacob Hannay课题组干细胞制造了人造小鼠胚胎 - 不需要精子或卵子 - 并使用创新的生物反应器来培育他们的创造物,其时间比以前的任何胚胎模型都要长。 ¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/LKn8nQ8GHA
¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs: Cell https://t.co/cpOL1OJ1Yd
RT @mason_lab: Amazing work with exowombs: "Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/wcHD…
RT @mason_lab: Amazing work with exowombs: "Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/wcHD…
Amazing work with exowombs: "Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/wcHD72UtYb
RT @Biyoteknolojitr: Araştırmacılar, sperm veya yumurtaya ihtiyaç duymadan, kök hücreleri kullanarak yapay embriyo üretti ve bunları rahim…
Araştırmacılar, sperm veya yumurtaya ihtiyaç duymadan, kök hücreleri kullanarak yapay embriyo üretti ve bunları rahim dışında uzun süre büyütmeyi başardı.
@BenBetzalel @rutihersh @Leia_Vain גם ברמת הממצאים עצמם, בלי מסגור ובלי השלכות הרות גורל על שאלות כמו חיים ומוות, הרי הם דרמטים בכל קנה מידה. עולה בדעתי ההשואה למחקר שפורסם לאחרונה של פרופ יעקוב חנא ממכון וייצמן שהצליח לגדל עובר סינטטי של עכבר מתאי גזע עובריים, בלי תא זרע, ביצית או רחם. https://t.co/rD2U5SpEj0
RT @Djindji4: Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/5l5h0cMsNv A synthetic mouse embr…
RT @Djindji4: Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/5l5h0cMsNv A synthetic mouse embr…
Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/5l5h0cMsNv A synthetic mouse embryo model on day 8 of its development https://t.co/S8kf7Lr0ec https://t.co/vEP1YMtUHP https://t.co/mwCydNPflg
"¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs" https://t.co/yBxcvVgwRk
¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/a2287pTKAY
RT @Biology1802: @DrAbdulmajeedFR لقراءة الورقة العلمية كاملة و معرفة كل التفاصيل المذهله هنا الرابط ⬇️⬇️ ¬Post-Gastrulation Synthetic Emb…
¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/79LrDta9Zt
Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs https://t.co/8e4e5khNjc
'Synthetic mouse embryos created from stem cells — without sperm, eggs, or a uterus.' Paper: https://t.co/4KeZiXwOhc https://t.co/JBV7oiwZ2T @WeizmannScience @TechnionLive