J Immunother Precis Oncol August 2022 PMID 36034580

Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institute of Emory University Experience.

Dylan J Martini, T Anders Olsen, Subir Goyal, Yuan Liu, Sean T Evans, Emilie Elise Hitron, Greta Anne Russler, Lauren Yantorni, Sarah Caulfield, Jacqueline T Brown, Jamie M Goldman, Bassel Nazha, Bradley C Carthon, Wayne B Harris, Omer Kucuk

Mentions

37
Peak: 7 in Aug 2022
across 2 sources since Jun 2022

Extended reach

82,390
potential audience

Total likes

54

Video views

185

Mentions per month

Jun 2022 – Mar 2023

Where it's discussed

  • X / Twitter36 posts
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AI synopsis

What people are saying

The discussions reflect a moderate interest in the published research, with posts emphasizing its real-world relevance and potential impact on cancer treatment. The tone varies from informational sharing to subtle appreciation, as seen in references to interviews and engagement with specific data points, illustrating thoughtful but cautious attention to the findings.

AgreementNeither agree nor disagree

Most discussions acknowledge the significance of the study but do not explicitly endorse its conclusions, reflecting neutral agreement.

InterestModerate interest

Several posts show curiosity by sharing links to the article and highlighting the focus on combination immunotherapy, indicating moderate interest.

EngagementModerate engagement

Discussions involve referencing real-world data and sharing interviews, demonstrating active engagement with the details.

ImpactModerate impact

The collective mentions of real-world outcomes and new research imply a recognition of the study’s potential influence on treatment approaches.

Abstract in brief

  • The study reviewed 49 patients with metastatic renal cell carcinoma treated with immune checkpoint inhibitor combinations at Emory University between 2015 and 2020, focusing on real-world outcomes and side effects.
  • Most patients were older, male, white, and had clear cell RCC, with the majority receiving nivolumab and ipilimumab; over half experienced immune-related side effects, and some needed treatment delays or discontinuations due to toxicity.
  • The effectiveness of these treatments showed a median progression-free survival of about 8 months and an objective response rate of 33%, which appeared lower compared to other reported data, highlighting variability in real-world treatment outcomes.]

Top posts

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JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikv8jM @bilenma #CombinationTherapy #Immunotherapy https://t.co/q4djuTuNDF

Aug 19, 2022 · 11 likes · 6 shares · 816 followers View post →
JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikMJIm @bilenma #CombinationTherapy #Immunotherapy https://t.co/2ZatMOMY9H

Sep 7, 2022 · 10 likes · 6 shares · 816 followers View post →
JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikMJIm @bilenma #CombinationTherapy #Immunotherapy https://t.co/AP4GCK0Hz9

Nov 25, 2022 · 8 likes · 3 shares · 816 followers View post →
JIPO Editors
@JIPOEditors · X

New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: The @WinshipAtEmory Experience, by Martini, Bilen et al. https://t.co/gEectYJ08L #Immunotherapy #oncology @bilenma @ANaingMD @weoncologists @SewantiLimaye https://t.co/PedPgDTIZt

Jun 16, 2022 · 6 likes · 7 shares · 816 followers View post →
JIPO Editors
@JIPOEditors · X

"Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co/GvvPikv8jM @bilenma #CombinationTherapy #Immunotherapy #JIPO @DenizCanGuven1 @jibranahmed1 @mirella_nardo @s02shambhavi @aysunyklmz https://t.co/Gs2zp3qNek

Oct 24, 2022 · 5 likes · 4 shares · 816 followers View post →
JIPO Editors
@JIPOEditors · X

#JIPO fellow Dr. Singh interview Dr. Bilen about his research ""Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma"" Watch: https://t.co/2H5eOeoyPm Read: https://t.co/GvvPikMJIm @s02shambhavi @bilenma

Nov 4, 2022 · 5 likes · 2 shares · 816 followers View post →

All mentions

CancerLinks 
@CancerLinks · X

RT @JIPOEditors: #TBT Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcino…

Mar 31, 2023 · 1 share · 97 followers View post →
JIPO Editors
@JIPOEditors · X

#TBT Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikMJIm @bilenma #CombinationTherapy #Immunotherapy https://t.co/EqUg2kXjYA

Mar 30, 2023 · 3 likes · 1 share · 816 followers View post →
Winship Cancer Institute of Emory University
@WinshipAtEmory · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Nov 28, 2022 · 3 shares · 10,295 followers View post →
Sewanti Limaye
@SewantiLimaye · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Nov 25, 2022 · 3 shares · 3,119 followers View post →
CancerLinks 
@CancerLinks · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Nov 25, 2022 · 3 shares · 97 followers View post →
JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikMJIm @bilenma #CombinationTherapy #Immunotherapy https://t.co/AP4GCK0Hz9

Nov 25, 2022 · 8 likes · 3 shares · 816 followers View post →
Aysun Ş. Yıkılmaz
@aysunsenturk · X

RT @JIPOEditors: #JIPO fellow Dr. Singh interview Dr. Bilen about his research ""Combination Immune Checkpoint Blockade Regimens for Previo…

Nov 5, 2022 · 2 shares · 280 followers View post →
Sewanti Limaye
@SewantiLimaye · X

RT @JIPOEditors: #JIPO fellow Dr. Singh interview Dr. Bilen about his research ""Combination Immune Checkpoint Blockade Regimens for Previo…

Nov 4, 2022 · 2 shares · 3,119 followers View post →
JIPO Editors
@JIPOEditors · X

#JIPO fellow Dr. Singh interview Dr. Bilen about his research ""Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma"" Watch: https://t.co/2H5eOeoyPm Read: https://t.co/GvvPikMJIm @s02shambhavi @bilenma

Nov 4, 2022 · 5 likes · 2 shares · 816 followers View post →
Deniz Can Guven
@DenizCanGuven1 · X

RT @JIPOEditors: "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co…

Oct 25, 2022 · 4 shares · 2,475 followers View post →
Dr Mukesh Rulaniya
@RulaniyaDr · X

RT @JIPOEditors: "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co…

Oct 24, 2022 · 4 shares · 578 followers View post →
Jibran Ahmed
@jibranahmed1 · X

RT @JIPOEditors: "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co…

Oct 24, 2022 · 4 shares · 96 followers View post →
Aysun Ş. Yıkılmaz
@aysunsenturk · X

RT @JIPOEditors: "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co…

Oct 24, 2022 · 4 shares · 280 followers View post →
JIPO Editors
@JIPOEditors · X

"Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma..." https://t.co/GvvPikv8jM @bilenma #CombinationTherapy #Immunotherapy #JIPO @DenizCanGuven1 @jibranahmed1 @mirella_nardo @s02shambhavi @aysunyklmz https://t.co/Gs2zp3qNek

Oct 24, 2022 · 5 likes · 4 shares · 816 followers View post →
Aysun Ş. Yıkılmaz
@aysunsenturk · X

JIPO Interview: Dr Mehmet Bilen shares real-world data from front-line I... https://t.co/rkjJaUWR0j @YouTube aracılığıyla

Oct 22, 2022 · 2 likes · 280 followers View post →
Sewanti Limaye
@SewantiLimaye · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 9, 2022 · 6 shares · 3,119 followers View post →
Jibran Ahmed
@jibranahmed1 · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 7, 2022 · 6 shares · 96 followers View post →
Dr Mukesh Rulaniya
@RulaniyaDr · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 7, 2022 · 6 shares · 578 followers View post →
Teoman Yanmaz
@mtymtyyanmaz · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 7, 2022 · 6 shares · 995 followers View post →
Deniz Can Guven
@DenizCanGuven1 · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 7, 2022 · 6 shares · 2,475 followers View post →
Aysun Ş. Yıkılmaz
@aysunsenturk · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Sep 7, 2022 · 6 shares · 280 followers View post →
JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikMJIm @bilenma #CombinationTherapy #Immunotherapy https://t.co/2ZatMOMY9H

Sep 7, 2022 · 10 likes · 6 shares · 816 followers View post →
Jacqueline T. Brown, MD
@jackiebrown_MD · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Aug 25, 2022 · 6 shares · 494 followers View post →
Winship Cancer Institute of Emory University
@WinshipAtEmory · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Aug 25, 2022 · 6 shares · 10,295 followers View post →
Hour of Science
@hour_of_science · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell C... https://t.co/ch12HEqk0S

Aug 25, 2022 · 111 followers View post →
Aysun Ş. Yıkılmaz
@aysunsenturk · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Aug 25, 2022 · 6 shares · 280 followers View post →
Sewanti Limaye
@SewantiLimaye · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Aug 19, 2022 · 6 shares · 3,119 followers View post →
Deniz Can Guven
@DenizCanGuven1 · X

RT @JIPOEditors: Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: T…

Aug 19, 2022 · 6 shares · 2,475 followers View post →
JIPO Editors
@JIPOEditors · X

Read in #JIPO "Combination Immune Checkpoint Blockade Regimens for Previously Untreated Metastatic Renal Cell Carcinoma: The Winship Cancer Institue of Emory University Experience" by Martini et al. here https://t.co/GvvPikv8jM @bilenma #CombinationTherapy #Immunotherapy https://t.co/q4djuTuNDF

Aug 19, 2022 · 11 likes · 6 shares · 816 followers View post →
Innovative Oncology Network
@OncologyNetwork · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jul 24, 2022 · 7 shares · 140 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jul 1, 2022 · 7 shares · 3,378 followers View post →
Stefania Colasanti
@Stefani19753108 · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jun 18, 2022 · 7 shares · 843 followers View post →
Mehmet AYDIN
@DrMhmtAYDINmd · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jun 17, 2022 · 7 shares · 110 followers View post →
Winship Cancer Institute of Emory University
@WinshipAtEmory · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jun 16, 2022 · 7 shares · 10,295 followers View post →
Gil Morgan, MD
@weoncologists · X

RT @JIPOEditors: New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: Th…

Jun 16, 2022 · 7 shares · 16,361 followers View post →
JIPO Editors
@JIPOEditors · X

New in #JIPO: Combination immune checkpoint blockade regimens for previously untreated metastatic renal cell carcinoma: The @WinshipAtEmory Experience, by Martini, Bilen et al. https://t.co/gEectYJ08L #Immunotherapy #oncology @bilenma @ANaingMD @weoncologists @SewantiLimaye https://t.co/PedPgDTIZt

Jun 16, 2022 · 6 likes · 7 shares · 816 followers View post →