Nat Rev Clin Oncol October 2022 PMID 36068272

Is early-onset cancer an emerging global epidemic? Current evidence and future implications.

Tomotaka Ugai, Naoko Sasamoto, Hwa-Young Lee, Mariko Ando, Mingyang Song, Rulla M Tamimi, Ichiro Kawachi, Peter T Campbell, Edward L Giovannucci, Elisabete Weiderpass, Timothy R Rebbeck, Shuji Ogino

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679

Peak: 39 in Sep 2022

across 7 sources since Sep 2022

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AI synopsis

What people are saying

The overall tone reflects serious concern and recognition of the rising incidence of early-onset cancers, with exchanges citing authoritative sources like the Nature Reviews article and highlighting lifestyle factors such as diet, obesity, and environmental exposures. Words like 'alarming,' 'fascinating,' and references to research and prevention underscore a high level of engagement and acknowledgment of the potential profound impact on public health.

AgreementStrong agreement

Most discussions acknowledge the rise of early-onset cancers and seem to agree on its significance, with many referencing the authoritative publication and highlighting lifestyle and environmental factors.

InterestHigh interest

The collective interest is high, as many posts delve into potential causes, implications, and prevention strategies, indicating strong engagement with the topic.

EngagementHigh engagement

Posts go beyond surface-level comments, often sharing studies, asking questions, and discussing genetic, lifestyle, and environmental factors, reflecting deep involvement.

ImpactHigh impact

The discussions emphasize the potential global health crisis, with some posts calling it an 'alarming' trend and referencing ongoing research and policy implications, suggesting significant perceived impact.

Abstract in brief

The incidence of early-onset cancers, diagnosed in adults under 50, has increased globally across various types, partly due to better screening and a genuine rise in cases, possibly linked to changes in lifestyle, environment, and genetics.
Changes in early life exposures, such as diet, obesity, and environmental factors, over recent decades may play a role in these increased cancer risks, but the specific impacts of individual factors are still unclear.
Addressing this growing concern requires prospective studies to understand early-life exposures better, as well as increased awareness among healthcare providers and the public to implement effective prevention strategies.]

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Why Is Cancer Increasing Among Young People? Key Factors and Risks

Suscrbete a mi Newsletter httpsdrsanagustinsubstackcom Hay trabajos de investigacin que sugieren un aumento de cncer diagnosticado en menores de 50 aos. Changes in early life exposures, such as diet, obesity, and…

Dr. Alberto Sanagustín · Sep 19, 2022 28,431 views

Rise in Early-Onset Cancers: Causes and Prevention Strategies

Cancer in young people has skyrocketed. Factors beyond genetics, including lifestyle and environmental exposures, may drive this trend. Experts emphasize the importance of awareness and early detection to reduce risk.

Dr Esh · Nov 10, 2024 1,530 views

Rising Cancer Rates Among Young People: Causes and Trends

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Kobi · Jul 17, 2024 236 views

Historical Landmarks in Cancer Treatment and Early Detection Strategies

Early historical records show that ancient doctors and surgeons gradually advanced their understanding of cancer, emphasizing early detection and complete removal for better outcomes, principles that continue to…

مع ناصر · Nov 14, 2022 212 views

Wireless Warrior

@Anti5GWarrior · X

"Is early-onset cancer an emerging global epidemic? Current evidence and future implications" https://t.co/croVc5yszD

Sep 19, 2025 · 2,795 followers View post →

Good vs Evil

@aFoxy10 · X

Doctors of Yale Medicine have observed that younger adults tend to have more aggressive-appearing cancers compared to older adults. This difference is seen in various cancer types, including colorectal, gastric and esophageal cancers and breast cancer. https://t.co/liXyVdt2wD

Sep 2, 2025 · 414 followers View post →

Andrea Stephany

@andreastephanyd · X

RT @VivekSubbiah: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Onc…

Aug 12, 2025 · 11 shares · 373 followers View post →

Dr. Amy C. Moore

@acmoorephd · X

RT @VivekSubbiah: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Onc…

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VinnDoc

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RT @VivekSubbiah: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Onc…

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RT @VivekSubbiah: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Onc…

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/3aAXhljzcn

Aug 11, 2025 · 23 likes · 11 shares · 38,721 followers View post →

Wireless Warrior

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"American Cancer Society - Cancer Facts & Figures 2025": https://t.co/Mna3sw3aIx "Is early-onset cancer an emerging global epidemic? Current evidence and future implications" https://t.co/ukav1M1Gth

Jul 9, 2025 · 1 like · 2,795 followers View post →

Wireless Warrior

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"Is early-onset cancer an emerging global epidemic? Current evidence and future implications": https://t.co/croVc5yszD IFS Report - "The number of new disability benefit claimants has doubled in a year" https://t.co/YNnqXaCVas

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Michael Klipstein

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Apr 5, 2025 · 349 followers View post →

Esh Tatla

@EshTatla · X

Why are so many young people getting cancer? I dive into why early-onset cancer is rising at an alarming rate and what you can do to prevent it. Watch here: https://t.co/01Dai9qPQu https://t.co/YXIi3t9Lcm

Nov 14, 2024 · 1 like · 349 followers View post →

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Aug 14, 2024 · 189 followers View post →

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications https://t.co/WkOvdYZSBR

May 21, 2024 · 451 followers View post →

Hacker News Top 100 Bot (Unofficial)

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Is early-onset cancer an emerging global epidemic? (2022) Discussion

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Kimmie Ng, MD, MPH

@KimmieNgMD · X

RT @TomGallagherHPB: Young onset #PDAC⬆️frequency

Jan 20, 2024 · 2 shares · 3,141 followers View post →

Fergus Keane

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RT @TomGallagherHPB: Young onset #PDAC⬆️frequency

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Tom Gallagher

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Young onset #PDAC⬆️frequency

Jan 19, 2024 · 6 likes · 2 shares · 633 followers View post →

je suis charlie

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Aantal gevallen van kanker stijgt enorm….#kanker Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/WWxMeWgD12

Dec 21, 2023 · 1 like · 1,177 followers View post →

IBIONS - Nutrición y Cáncer

@ibionsnutricion · X

Ugai, T., Sasamoto, N., Lee, HY. et al. Is early-onset cancer an emerging global epidemic? Current evidence and future implications. Nat Rev Clin Oncol 19, 656–673 (2022). https://t.co/Vpfx1xj0CH https://t.co/rRJ7NuT83J

Oct 3, 2023 · 1 like · 123 followers View post →

Ming Web

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Aug 17, 2023 · 1 like · 36 followers View post →

Global AYA Cancer Congress

@AYAGlobalCancer · X

“Is Early-Onset Cancer an Emerging Global Epidemic? Current Evidence and Future Implications” with Tomotaka Ugai Brigham & Women's Hospital, Harvard Medical School @harvardmed @BrighamWomens #AYACancerCongress #gayacc #CancerResearch #oncology #oncologyresearch https://t.co/5zwQqvHZCk

Jun 21, 2023 · 2 likes · 1,057 followers View post →

Amilcar De Oliveira

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications. https://t.co/gc47XGV3Iu

May 23, 2023 View post →

Agathonia Media

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Is early-onset cancer an emerging global epidemic? Current #evidence and #future implications https://t.co/IuKwTAvHQN

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A propos de l'article « Is early-onset cancer an emerging global epidemic ? Current evidence and future implication » https://t.co/Uzz4YINAN7 https://t.co/kptzy8JTvj

Jan 13, 2023 · 113 followers View post →

Mahmoud Delphan

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RT @FrezzaLab: Our lifestyle is not very healthy. Who would have predicted this? Is early-onset cancer an emerging global epidemic? Curren…

Dec 31, 2022 · 1 share · 29 followers View post →

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ねこ@医療ライター

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications https://t.co/JFyAfrSBnd

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RT @BatlleLab: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncolo…

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/AIjI67YO7v

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RT @JDekervel: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncolo…

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/inl2BQOGXt

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Original article for those who would like to dig in: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/7Dzw41uuJp

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RT @SueChappel: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncol…

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RT @SueChappel: Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncol…

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Dr.Suzanne Chappel

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/d9ickZWOqy

Dec 4, 2022 · 3 likes · 2 shares · 2,768 followers View post →

Rob de Kok

@mobirob · X

Heftig dit. Helaas ook zichtbaar in mijn omgeving. Vermoedens? Ja. Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/MaL5lVbwlS

Dec 1, 2022 · 448 followers View post →

Christine

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Is early-onset cancer an emerging global epidemic? Current evidence and future implications | Nature Reviews Clinical Oncology https://t.co/m7KdpaGr59

Nov 28, 2022 · 1,526 followers View post →

Joel Selanikio

@jselanikio · X

Is early-onset cancer an emerging global epidemic? New paper in NatRevClinOncol raises important questions. https://t.co/VyuUWAzSP5 ht @AlisonBuist via @dianabuist #oncology #cancer #globalhealth

Nov 22, 2022 · 1 like · 3,612 followers View post →

CitadinLe

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RT @barriere_dr: « On voit de plus en plus de cancers chez les jeunes ! » Légende urbaine? https://t.co/wIN7LFR2m3 https://t.co/DSuplTFj…

Nov 19, 2022 · 1 share · 159 followers View post →

Dr Jérôme BARRIERE, MD.

@barriere_dr · X

« On voit de plus en plus de cancers chez les jeunes ! » Légende urbaine? https://t.co/wIN7LFR2m3 https://t.co/DSuplTFjE8

Nov 18, 2022 · 11 likes · 1 share · 31,349 followers View post →

David García-González

@DavidGarcaGonz6 · X

Very interesting paper for today. https://t.co/yT5giL0uS0

Nov 14, 2022 · 1 like · 94 followers View post →

Guscanarias

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