September 2022 PMID 36100950

The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows.

Dipti W Pitta, Nagaraju Indugu, Audino Melgar, Alexander Hristov, Krishna Challa, Bonnie Vecchiarelli, Meagan Hennessy, Kapil Narayan, Stephane Duval, Maik Kindermann, Nicola Walker

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Mentions

76
Peak: 47 in Dec 2024
across 4 sources since Sep 2022

Extended reach

201,308
potential audience

Total likes

164

Video views

626

Mentions per month

Sep 2022 – May 2025

Where it's discussed

  • X / Twitter64 posts
  • News9 articles
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

Discussions highlight the varying success of methane mitigation strategies, with several participants referencing specific metabolic processes affected by 3-nitrooxypropanol, such as the reduction of Methanobrevibacter species. Comments like 'the impact will first show up in changes to the cow's microbiome' and criticisms of other strategies underscore a recognition of the complexities involved, showing how choice of words like 'adverse effects’ and ‘limited practical use’ reflect the cautious yet hopeful tone regarding the study's implications.

AgreementModerate agreement

Many discussions express a positive reception of 3-nitrooxypropanol as a methane inhibitor, suggesting a general consensus on its potential benefits.

InterestHigh interest

There is significant curiosity surrounding the implications of the research, with many participants discussing its relevance to both environmental and agricultural practices.

EngagementModerate engagement

Though engagement varies, several discussions dive into the nuances of methane production and the effectiveness of 3NOP, indicating a moderate level of interaction with the content.

ImpactHigh impact

A strong belief in the publication's potential influence on farming practices and methane emissions is evident, showing that participants think it could lead to practical changes in dairy farming.

Abstract in brief

  • This study examines how 3-nitrooxypropanol (3NOP), a methane inhibitor, affects the microbial gene expression in the rumen of dairy cows, aiming to reduce methane emissions during digestion.
  • 3NOP primarily inhibits the enzyme responsible for methane formation, leading to shifts in hydrogen production and microbial activity, particularly affecting Methanobrevibacter species more than others.
  • The research utilizes advanced techniques to reveal that while methane production decreases, other metabolic pathways, like butyrate synthesis, may increase to manage hydrogen levels in the rumen, providing new insights into rumen microbiome dynamics.

Top posts

Most liked on X and Bluesky
Moneytrainers - An Adviser in Recovery
@Moneytrainers · X

@LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from around 600 m tonnes of cattle world wide? Adding seaweed to cattle feed reduces emissions by 60%, they could have done that and not had a milk boycott.https://t.co/abeHbNuOQl

Dec 2, 2024 · 115 likes · 22 shares · 477 followers View post →
Dr Henry Ealy
@DrHenryEaly · X

The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 32 likes · 14 shares · 58,269 followers View post →
Peter Romanowski (MSc/AI student)
@PitRomanowski86 · X

@Jedisurfer1 @909isLive What I managed to gather so far none are studying prolong effects of humans. pdf share: https://t.co/pn9S6IFkXQ ref: https://t.co/RAcHgBqg57 https://t.co/6MQNbKesKW https://t.co/mMJDYIEbDc https://t.co/MtDPjd83xs https://t.co/e4EYYS5azP https://t.co/DTOVXY8RhM https://t.co/UfKk245ZqM

Nov 28, 2024 · 4 likes · 3 shares · 1,054 followers View post →
Mike Jetten
@msmjetten · X

The effect of 3-nitrooxypropanol, a potent #methane inhibitor, on ruminal microbial gene expression profiles in dairy cows #methanogenesis https://t.co/Etuc3LR0U3

Sep 15, 2022 · 2 likes · 1 share · 6,722 followers View post →
Patrick Heizer
@PatrickHeizer · X

@AdamLasch1 Here: https://t.co/duoMYK20z4

Nov 28, 2024 · 1 like · 4,678 followers View post →
Kari Ruokola
@KRuokola · X

Mitä pötsissä tapahtuu?https://t.co/zpI0j2lthz

Dec 4, 2024 · 1 like · 410 followers View post →

All mentions

Peasant with a PhD
@PeteGDunne · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

May 11, 2025 · 14 shares · 3,080 followers View post →
kapitaali.com
@kapitaali__com · X

@hirvelanjuho @s_jarmo niitä aineenvaihduntatuotteita on aika hemmetin monta, suomalaisissa tutkimuksissa pitäis ilmottaa kaikkien näiden jäämien määrät https://t.co/daOxvA64yH https://t.co/WprU3rdZzg

Jan 1, 2025 · 1 like · 123 followers View post →
Criticalitem007
@criticalitem007 · X

RT @PitRomanowski86: @Jedisurfer1 @909isLive What I managed to gather so far none are studying prolong effects of humans. pdf share: https…

Dec 14, 2024 · 3 shares · 2,017 followers View post →
katcher
@distribute · X

@BritLad95 They should read, 3-NOP: Mitigation strategies have had varying degrees of success, with some strategies showing adverse effects on animal health and production - and also on the environment [5], indicating their limited practical use on farms. https://t.co/eVkNDlOOF2

Dec 9, 2024 · 1,184 followers View post →
katcher
@distribute · X

@BritLad95 3-NOP: "Different mitigation strategies have had varying degrees of success, with some strategies accompanied by adverse effects on animal health and production and also on the environment [5], indicating their limited practical use on farms". https://t.co/eVkNDlOOF2

Dec 9, 2024 · 1,184 followers View post →
katcher
@distribute · X

@realTrumpNewsX 3-NOP, these different mitigation strategies have had varying degrees of success, with some strategies accompanied by adverse effects on animal health and production and also on the environment [5], indicating their limited practical use on farms. https://t.co/eVkNDlOOF2

Dec 9, 2024 · 1,184 followers View post →
Courtney Galina ⚡️
@MuseMelodic · X

@wolsned @ArlaFoodsUK Source: https://t.co/SdNxOEmpkh https://t.co/A78Gu5OtyM

Dec 8, 2024 · 754 followers View post →
Markku Antero
@MarkkuAnteroX · X

@hirvelanjuho Oletkos muuten koulutukseltasi biokemisti ja tunnet sekä aineen, että lehmän metabolian niin hyvin, että pystyt laatimaan aiheesta kaiken jo kerätyn tiedon kumoavan tutkimusartikkelin? Aloita vaikka kumoamalla tämän tutkimuksen tiedot. https://t.co/yRvb1BYPfJ

Dec 5, 2024 · 117 followers View post →
HappiPlace32
@HPlace32 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 4, 2024 · 22 shares · 401 followers View post →
SD
@Baffled27 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 4, 2024 · 14 shares · 249 followers View post →
Grace Robertson
@gracerob50 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 4, 2024 · 22 shares · 1,936 followers View post →
Kari Ruokola
@KRuokola · X

Mitä pötsissä tapahtuu?https://t.co/zpI0j2lthz

Dec 4, 2024 · 1 like · 410 followers View post →
KellyRoze
@Kelly4Infowars · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 5,942 followers View post →
the eye
@watch1984 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 3, 2024 · 22 shares · 2,272 followers View post →
Shelli L Dellinger
@thegirlsclub3 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 595 followers View post →
Tony Opondo
@Opondo2022Tony · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 179 followers View post →
Sundevil89
@Sundevil891 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 1,978 followers View post →
Hexbar
@Hexbar2 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 407 followers View post →
LinnyGF
@linnyflintham · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 3, 2024 · 22 shares · 2,016 followers View post →
Karen Walker
@ImmuneHealthMom · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 2,207 followers View post →
☄☆☄J9 ☄☆☄
@J9P814 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 1,212 followers View post →
GrinerATodd
@supertodd1 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 1,566 followers View post →
Lisa Lynne
@LisaLynne · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 333 followers View post →
MAGA/MAHA Mimi
@momben10 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 2,941 followers View post →
DebraJ
@deebs001 · X

RT @DrHenryEaly: The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 14 shares · 1,314 followers View post →
Dr Henry Ealy
@DrHenryEaly · X

The impact will first show up in changes to the cow's microbiome...

Dec 3, 2024 · 32 likes · 14 shares · 58,269 followers View post →
Jedisurfer
@Jedisurfer1 · X

RT @PitRomanowski86: @Jedisurfer1 @909isLive What I managed to gather so far none are studying prolong effects of humans. pdf share: https…

Dec 3, 2024 · 3 shares · 253 followers View post →
Annabelle Valentine
@AnnabelleV94084 · X

RT @PitRomanowski86: @Jedisurfer1 @909isLive What I managed to gather so far none are studying prolong effects of humans. pdf share: https…

Dec 3, 2024 · 3 shares · 4 followers View post →
Elle Alder
@HEAlderman22 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 3, 2024 · 22 shares · 1,643 followers View post →
ShortieT
@shortietskippy · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 485 followers View post →
Stevo Tillydude
@tillydude28757 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 2,083 followers View post →
jackiebrown
@jackiebrow99232 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 151 followers View post →
VOBE_s
@VOBE_s · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 409 followers View post →
Liberty
@noc65342 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 518 followers View post →
Subrosa
@scots_subrosa · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 2,443 followers View post →
Alexblx
@Alexblx · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 4,623 followers View post →
Mike
@John_v925 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 745 followers View post →
Caro - NO TO SELF ID
@100_born · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 1,627 followers View post →
P1P3R00
@P1P3R00 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 1,301 followers View post →
SophiaMatrina
@AlphaTrw61759 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 850 followers View post →
Precocious_D
@G4offr4y · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 1,915 followers View post →
Heidi
@heidiEC5 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 13,305 followers View post →
@susi_d
@susi_d · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 1,294 followers View post →
Brendy
@BrendaJ98869280 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 2,846 followers View post →
me
@stevebridge6519 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 167 followers View post →
157pipers
@157pipers · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 628 followers View post →
LadyCBBBB
@Carole1258 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 3,079 followers View post →
Trudi West
@TJ092011 · X

RT @Moneytrainers: @LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from aroun…

Dec 2, 2024 · 22 shares · 3,120 followers View post →
Moneytrainers - An Adviser in Recovery
@Moneytrainers · X

@LeilaniDowding @marksandspencer The figures are made up and don't make sense. 12.5bn tonnes of gases, coming from around 600 m tonnes of cattle world wide? Adding seaweed to cattle feed reduces emissions by 60%, they could have done that and not had a milk boycott.https://t.co/abeHbNuOQl

Dec 2, 2024 · 115 likes · 22 shares · 477 followers View post →
Peter Romanowski (MSc/AI student)
@PitRomanowski86 · X

@Jedisurfer1 @909isLive What I managed to gather so far none are studying prolong effects of humans. pdf share: https://t.co/pn9S6IFkXQ ref: https://t.co/RAcHgBqg57 https://t.co/6MQNbKesKW https://t.co/mMJDYIEbDc https://t.co/MtDPjd83xs https://t.co/e4EYYS5azP https://t.co/DTOVXY8RhM https://t.co/UfKk245ZqM

Nov 28, 2024 · 4 likes · 3 shares · 1,054 followers View post →
Patrick Heizer
@PatrickHeizer · X

@AdamLasch1 Here: https://t.co/duoMYK20z4

Nov 28, 2024 · 1 like · 4,678 followers View post →
David Paton
@DavidPa30751924 · X

@SenRonJohnson Our favorite state loves cows… this is what Bill Gates wants to feed them https://t.co/avS9eKbp3b

Nov 27, 2024 · 587 followers View post →
EnoughAlready
@2Shirleylind · X

@ArlaFoodsUK @Morrisons @Tesco @AldiUK We do not consent https://t.co/peQEmEHEi6

Nov 27, 2024 · 139 followers View post →
Evald Ever
@Gaiatuuli · X

@MKartesalo 3-NOP on EU: ssa hyväksytty aine jota kokeillaan lehmien metaani tuotannon vähentämiseen. https://t.co/VrhDr4Cfy9

Jun 2, 2024 · 22 followers View post →
Erwin Boydens
@ErwinBoydens · X

Meer in detail https://t.co/moZ9q7qHNC

Dec 28, 2023 · 2,445 followers View post →
Daniel Park
@Daniel_E_Park · X

@stclairashley Slaughtering them? Why aren't we just doing this? https://t.co/MShK3VElRh https://t.co/aAe04spTAB

Jun 3, 2023 · 6,865 followers View post →
James Hadfield
@coregenomics · X

@BioMickWatson "In cows that received 3-NOP supplementation, the relative abundance of Methanobrevibacter was lower"...so it did reduce one species abundance. Did other, lower methane producing, methano-archea fill the niche? https://t.co/tGz4TbMbPT

Apr 4, 2023 · 7,091 followers View post →
Diii
@cha_ss86 · X

@SEater45 @WallStreetSilv Science mate... SCIENCE! source A: https://t.co/7ThSS77932 Source B: https://t.co/D6TZsR4H1u

Feb 2, 2023 · 177 followers View post →
Transcriptomes
@transcriptomes · X

The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expre... https://t.co/lcwJtw2mhi

Sep 16, 2022 · 1,810 followers View post →
Dr. Geo (Michel Geovanni Santiago-Martínez, PhD)
@GeoSantiagoM · X

RT @msmjetten: The effect of 3-nitrooxypropanol, a potent #methane inhibitor, on ruminal microbial gene expression profiles in dairy cows #…

Sep 15, 2022 · 1 share · 5,520 followers View post →
Mike Jetten
@msmjetten · X

The effect of 3-nitrooxypropanol, a potent #methane inhibitor, on ruminal microbial gene expression profiles in dairy cows #methanogenesis https://t.co/Etuc3LR0U3

Sep 15, 2022 · 2 likes · 1 share · 6,722 followers View post →
Microbiome
@MicrobiomeJ · X

The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows https://t.co/RjDQkv1Laf

Sep 14, 2022 · 20,395 followers View post →
FeOM Research
@FeOM_Research · X

The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows https://t.co/SRJ5Ylqdbk

Sep 14, 2022 · 124 followers View post →
Metagenomics Papers
@metagenomic_lit · X

The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows https://t.co/noVHjowHhh

Sep 14, 2022 · 3,698 followers View post →