Physiol Behav December 2022 PMID 36126693

Lactobacillus plantarum ST-III modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder.

Min Guo, Ruiying Li, Yuezhu Wang, Shiyu Ma, Yilin Zhang, Sheng Li, Hongfa Zhang, Zhenmin Liu, Chunping You, Huajun Zheng

Mentions

9
Peak: 5 in Oct 2025
across 2 sources since Sep 2022

Extended reach

11,589
potential audience

Total likes

64

Video views

3,182

Mentions per month

Sep 2022 – Oct 2025

Where it's discussed

  • YouTube6 videos
  • X / Twitter3 posts

AI synopsis

What people are saying

The discussions reflect a cautiously optimistic view, with comments like '#microbiome' and references to the probiotic’s ability to modulate behavior and gut health, showing that users are engaged with the possible clinical applications of the research. The tone varies from scientific acknowledgment to speculative optimism, emphasizing the perceived importance of microbiome interventions for ASD.

AgreementModerate agreement

Most posts acknowledge the study's findings, with some expressing support for the potential of probiotics like Lactobacillus plantarum ST-III in addressing behavioral symptoms associated with ASD.

InterestModerate interest

The discussion shows moderate curiosity about the topic, with users highlighting specific bacteria and metabolic pathways, indicating some engagement beyond surface-level mentions.

EngagementModerate engagement

Several posts reference the mechanisms and potential implications of the research, suggesting active interest and a desire to explore its significance.

ImpactModerate impact

Participants imply that this study could influence future research or therapies related to ASD and gut microbiota, indicating perceived potential in the findings.

Abstract in brief

  • The study found that oral treatment with Lactobacillus plantarum STIII can improve social behavior and reduce repetitive actions in a mouse model of autism spectrum disorder (ASD) created using triclosan.
  • The probiotic also altered gut microbiota by increasing beneficial bacteria like Lachnospiraceae and decreasing harmful bacteria like Alistipes, which was linked to behavioral improvements.
  • These results suggest that L. plantarum STIII may help restore gut balance and alleviate some ASD symptoms by influencing gut bacteria and related metabolic pathways.]

Top posts

Most liked on X and Bluesky
Symbiosis papers
@Symbiosispapers · X

Lactobacillus plantarum ST-III modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder https://t.co/4OgX7ASTBn

Sep 21, 2022 · 1 like · 1,110 followers View post →
Microbiome Articles
@microbe_article · X

Lactobacillus plantarum st-iii modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder. - Guo M et al. - https://t.co/yGmBgfp2To #microbiome

Sep 21, 2022 · 7,156 followers View post →

All mentions

Lars Peterson
@FermentiLlc · X

#triclosan causes #autism in offspring of #microbime damaged mothers then is reversed with commensal L.A.B.'s. Lactobacillus plantarum ST-III modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder https://t.co/P1zgsGzpDL #greatdnahijack

Jul 23, 2023 · 143 followers View post →
Microbiome Articles
@microbe_article · X

Lactobacillus plantarum st-iii modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder. - Guo M et al. - https://t.co/yGmBgfp2To #microbiome

Sep 21, 2022 · 7,156 followers View post →
Symbiosis papers
@Symbiosispapers · X

Lactobacillus plantarum ST-III modulates abnormal behavior and gut microbiota in a mouse model of autism spectrum disorder https://t.co/4OgX7ASTBn

Sep 21, 2022 · 1 like · 1,110 followers View post →