PubHawk
September 2022 PMID 36137713

Incidence and Predictors of Early Death in Patients Undergoing Percutaneous Left Atrial Appendage Closure.

Jules Mesnier, Ignacio Cruz-González, Dabit Arzamendi, Xavier Freixa, Luis Nombela-Franco, Vicente Peral, Berenice Caneiro-Queija, Antonio Mangieri, Blanca Trejo-Velasco, Lluis Asmarats, Ander Regueiro, Angela McInerney, Caterina Mas-Lladó, Rodrigo Estevez-Loureiro, Alessandra Laricchia

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Mentions

76
Peak: 63 in Sep 2022
across 5 sources since Aug 2022

Extended reach

312,948
potential audience

Total likes

214

Video views

32

Mentions per month

Aug 2022 – Mar 2024

Where it's discussed

  • X / Twitter66 posts
  • YouTube3 videos
  • News3 articles
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Several posts highlight critical statistics from the research, such as the 15.5% early death rate and the impact of having multiple risk factors on mortality risk. Comments like, 'futile procedure in patients with comorbidities?' illustrate a critical analysis of the findings, while phrases like 'high risk in older patients' convey urgency and concern about patient selection. The tone of these discussions reflects a blend of concern and interest, emphasizing the importance of the study's conclusions for clinical decision-making.

AgreementModerate agreement

A majority of posts express support for the findings regarding mortality risks associated with the procedure, suggesting a consensus on the importance of the research.

InterestHigh interest

The discussions indicate strong curiosity about the implications of the publication, as users seek to understand the specifics of the data and its relevance to practice.

EngagementHigh engagement

Many posts delve into specific risk factors, methods, and clinical implications, demonstrating a deep engagement with the material and discussion about best practices.

ImpactHigh impact

Users perceive the findings as highly significant, noting the potential effects on patient selection and treatment approaches in clinical settings.

Abstract in brief

  • LAAC (Left Atrial Appendage Closure) is performed to prevent strokes in patients with atrial fibrillation, but early death within the first year can nullify its benefits.
  • In a study involving 807 patients over a decade, 15.5% experienced early death, with factors like older age, lower body mass index, diabetes, prior heart failure, and reduced kidney function significantly increasing this risk.
  • The findings suggest that having three or more of these risk factors can lead to a dramatically higher risk of early death, stressing the importance of careful patient selection for the procedure.
Read the full abstract

Top posts

Most liked on X and Bluesky
Mohamad Alkhouli
@adnanalkhouli · X

Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conferred a 1 year mortality risk of ~50% https://t.co/pVs77uuPrT https://t.co/1PbHAy916r

Sep 3, 2022 · 88 likes · 32 shares · 16,434 followers View post →
真鍋晋@心臓外科医
@Susumu_Manabe · X

カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 23, 2022 · 51 likes · 7 shares · 2,327 followers View post →
JACC Journals
@JACCJournals · X

In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage closure. Read more about these important observations regarding a preventive procedure in #JACCCEP: https://t.co/r3v5iCO5wJ #EPeeps #CardioTwitter https://t.co/sr3hCFqniT

Sep 22, 2022 · 44 likes · 17 shares · 114,706 followers View post →
CardioTeca
@cardioteca · X

Sep 21, 2022 · 19 likes · 8 shares · 36,606 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

【LAAC後の死亡率とリスク/ JACC CE】 スペイン、経皮的左心耳閉鎖施行の連続登録807例 [平均76歳] 解析：施行後１年以内に15.5%が死亡。多変量解析で残ったリスク因子は、「高齢」、「低BMI」、「DM」、「HF既往」、「eGFR低値」。リスクは相加的。 https://t.co/MtOV9d9DA8 https://t.co/CcwxAZP4ZR

Aug 31, 2022 · 7 likes · 2 shares · 4,902 followers View post →
Jose Albors Martin
@AlborsJose · X

From @jaccjournals https://t.co/ssr4O4jVPl Define futility @drjohnm, please

Sep 4, 2022 · 2 likes · 489 followers View post →

All mentions

Sahar Samimi, MD
@SaharSamimii · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Oct 13, 2022 · 32 shares · 1,215 followers View post →
Julia Valenzuela
@julia_valenz · X

RT @cardioteca:

Sep 27, 2022 · 8 shares · 256 followers View post →
Toshiki Kuno, MD, PhD, FESC, FSCAI
@ToshikiKuno · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 25, 2022 · 7 shares · 4,256 followers View post →
呼吸器内科医K
@ifitwasnt1 · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 599 followers View post →
りょ
@sonograpotter · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 960 followers View post →
Takuya Kishi @ねこ好き循環器内科医
@tkishi_cardiol · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 14,702 followers View post →
Hiroyuki Sato 佐藤宏行
@foreverhero0819 · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 3,806 followers View post →
まめたろう,MD, PhD
@mameeps · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 4,946 followers View post →
sentokun
@sentokunpcs · X

RT @Susumu_Manabe: カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 24, 2022 · 7 shares · 22,866 followers View post →
真鍋晋@心臓外科医
@Susumu_Manabe · X

カテーテルによる左心耳閉鎖術の施行後1年の総死亡が15.5%だったと。あくまで予防的措置なので、余命が見込めない高リスク症例での施行には慎重であるべきと。 From @jaccjournals https://t.co/85U3RV1Hu7

Sep 23, 2022 · 51 likes · 7 shares · 2,327 followers View post →
Yunox
@ysakamo27214609 · X

RT @KazNegishiMD: 左心耳閉鎖術後、6人に1人が1年以内に死亡。リスク因子は、年齢（78歳以上）、BMI低値（23未満）、DM,心不全の既往、腎機能低下(eGFR<50)。リスク印字が3つ以上あるとさらにハイリスク。 適応評価の参考に。 From @jacc…

Sep 23, 2022 · 5 shares · 66 followers View post →
Anjan Gupta
@ACSCardiology · X

In this registry, close to 1 in 6 patients died within the first year of LAAC. Older age, low body mass index, impaired estimated glomerular filtration rate, prior diabetes, and prior heart failure are at an increased risk. ⁦@drjohnm⁩ https://t.co/b6tVReJVJs

Sep 23, 2022 · 431 followers View post →
色々自粛中(ガラス細工の様な繊細なハートを持つ貴公子
@ECGEPSCADEVICE · X

RT @KazNegishiMD: 左心耳閉鎖術後、6人に1人が1年以内に死亡。リスク因子は、年齢（78歳以上）、BMI低値（23未満）、DM,心不全の既往、腎機能低下(eGFR<50)。リスク印字が3つ以上あるとさらにハイリスク。 適応評価の参考に。 From @jacc…

Sep 23, 2022 · 5 shares · 9,370 followers View post →
shuichi.N
@leon0705N · X

RT @KazNegishiMD: 左心耳閉鎖術後、6人に1人が1年以内に死亡。リスク因子は、年齢（78歳以上）、BMI低値（23未満）、DM,心不全の既往、腎機能低下(eGFR<50)。リスク印字が3つ以上あるとさらにハイリスク。 適応評価の参考に。 From @jacc…

Sep 23, 2022 · 5 shares · 222 followers View post →
Alberto Giannoni
@AlbertoGiannon8 · X

A futile procedure in patients with comorbidities? Incidence and Predictors of Early Death in Patients Undergoing Percutaneous Left Atrial Appendage Closure | JACC: Clinical Electrophysiology https://t.co/LgG1NEAnSQ

Sep 23, 2022 · 2 likes · 347 followers View post →
Daisuke Yakabe MD,PhD| 矢加部 大輔
@yakabe1206 · X

RT @KazNegishiMD: 左心耳閉鎖術後、6人に1人が1年以内に死亡。リスク因子は、年齢（78歳以上）、BMI低値（23未満）、DM,心不全の既往、腎機能低下(eGFR<50)。リスク印字が3つ以上あるとさらにハイリスク。 適応評価の参考に。 From @jacc…

Sep 22, 2022 · 5 shares · 4,758 followers View post →
Misako TOKI
@misako_desu · X

RT @KazNegishiMD: 左心耳閉鎖術後、6人に1人が1年以内に死亡。リスク因子は、年齢（78歳以上）、BMI低値（23未満）、DM,心不全の既往、腎機能低下(eGFR<50)。リスク印字が3つ以上あるとさらにハイリスク。 適応評価の参考に。 From @jacc…

Sep 22, 2022 · 5 shares · 942 followers View post →
Rahul Chaudhary MD, MBA, MSCS candidate
@RC_theheartdoc · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 148 followers View post →
Rami Kafa
@RamiKafa · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 1,181 followers View post →
Eduardo Zatarain
@EduZatarain · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 904 followers View post →
Reira Espinosa
@reira_espinosa · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 185 followers View post →
Felice Gragnano
@FeliceGragnano · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 5,355 followers View post →
Dr. Luiz Silva
@DrLuizSilva1 · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 392 followers View post →
Jörn Tongers
@JoernTongers_MD · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 116 followers View post →
EP_Bot
@EPeeps_Bot · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 8,533 followers View post →
J. Caro
@jcarocd · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 343 followers View post →
Gal Tsaban
@GalTsaban · X

RT @JACCJournals: In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage…

Sep 22, 2022 · 17 shares · 456 followers View post →
JACC Journals
@JACCJournals · X

In this multicenter international registry, close to 1 in 6 patients died within the first year of left atrial appendage closure. Read more about these important observations regarding a preventive procedure in #JACCCEP: https://t.co/r3v5iCO5wJ #EPeeps #CardioTwitter https://t.co/sr3hCFqniT

Sep 22, 2022 · 44 likes · 17 shares · 114,706 followers View post →
Joan Monell
@joan_monell · X

RT @cardioteca:

Sep 22, 2022 · 8 shares · 100 followers View post →
Antonio Gomez Menchero
@AntonioGomezM21 · X

RT @cardioteca:

Sep 22, 2022 · 8 shares · 685 followers View post →
СГАМ
@CGAM2016 · X

RT @cardioteca:

Sep 21, 2022 · 8 shares · 235 followers View post →
Ignacio Cruz Gonzalez
@icruzgonzalez · X

RT @cardioteca:

Sep 21, 2022 · 8 shares · 2,492 followers View post →
Rodrigo Estévez
@RodrigoEstvez1 · X

RT @cardioteca:

Sep 21, 2022 · 8 shares · 1,794 followers View post →
CardioTeca
@cardioteca · X

Sep 21, 2022 · 19 likes · 8 shares · 36,606 followers View post →
@investigando
@rocatanho · X

1 de c/6 pac mueren en 1er año post-cierre apéndice auricular izq , c/riesgo elevado en pacientes con edad avanzada, TFG baja, diabetes e insuficiencia cardíaca, siendo prohibitivo en presencia de más de estos 3 factores . #LAAC #earlydeath #riskfactors https://t.co/pz5th1SsuL

Sep 21, 2022 · 1 like · 398 followers View post →
J Mesnier
@JulesMesnier · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 5, 2022 · 32 shares · 39 followers View post →
Resi de Cardio
@RCardiologia · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 5, 2022 · 32 shares · 153 followers View post →
Xavier Freixa
@freixa_xavier · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 912 followers View post →
Aycan Erkan
@AycanErkan10 · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 350 followers View post →
Ramesh Adhikari MD
@Adhirams · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 395 followers View post →
Sunil Mankad MD
@MDMankad · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 1,211 followers View post →
Jose Albors Martin
@AlborsJose · X

From @jaccjournals https://t.co/ssr4O4jVPl Define futility @drjohnm, please

Sep 4, 2022 · 2 likes · 489 followers View post →
María Bastos
@MBastosFez · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 100 followers View post →
Giuseppe Marchese
@beppemarchese · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 649 followers View post →
Francesco Lauri
@laurifm86 · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 30 followers View post →
Jose Juan García
@2jeystone · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 160 followers View post →
Raquel Marzoa
@MarzoaRaquel · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 1,332 followers View post →
Dabit Arzamendi
@StructuralBCN · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 2,253 followers View post →
Lluis Asmarats
@AsmaratsL · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 803 followers View post →
Linda
@wordfinga · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 4,593 followers View post →
Pastor Perez Santigosa
@pastorluisps · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 102 followers View post →
Prof Dhiraj Gupta
@DhirajGuptaBHRS · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 4,969 followers View post →
la ode muhammadin
@matahana · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 4, 2022 · 32 shares · 122 followers View post →
Dr Arif, MD
@DrZiniuz · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 133 followers View post →
Domingo Luis Pozzer
@lpozzer · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 221 followers View post →
Abhishek Kulkarni
@AbhiKulk82 · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 520 followers View post →
Sahil Zaveri, MD
@SahilZaveriMD · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 2,486 followers View post →
Prosto Echo
@EchoProsto · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 148 followers View post →
Berenice Caneiro
@b_caneiro · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 482 followers View post →
José F. Rodríguez Palomares
@JRodriPalomares · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 2,282 followers View post →
Osama Bisht
@Obisht · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 6,420 followers View post →
Sergio R. de Leiras
@srdeleiras · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 2,434 followers View post →
Pedro Graziano Sanchez
@wikimagen · X

RT @adnanalkhouli: Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conf…

Sep 3, 2022 · 32 shares · 7,149 followers View post →
Mohamad Alkhouli
@adnanalkhouli · X

Predictors of 1 year mortality after left atrial appendage occlusion @JACCJournals The presence of 3 risk factors conferred a 1 year mortality risk of ~50% https://t.co/pVs77uuPrT https://t.co/1PbHAy916r

Sep 3, 2022 · 88 likes · 32 shares · 16,434 followers View post →
Ryo Horita, MD.
@hrt01a · X

RT @Office_j: 【LAAC後の死亡率とリスク/ JACC CE】 スペイン、経皮的左心耳閉鎖施行の連続登録807例 [平均76歳] 解析：施行後１年以内に15.5%が死亡。多変量解析で残ったリスク因子は、「高齢」、「低BMI」、「DM」、「HF既往」、「eGFR低…

Aug 31, 2022 · 2 shares · 1,434 followers View post →
宇津 貴史 /Utsu, Takashi
@Office_j · X

【LAAC後の死亡率とリスク/ JACC CE】 スペイン、経皮的左心耳閉鎖施行の連続登録807例 [平均76歳] 解析：施行後１年以内に15.5%が死亡。多変量解析で残ったリスク因子は、「高齢」、「低BMI」、「DM」、「HF既往」、「eGFR低値」。リスクは相加的。 https://t.co/MtOV9d9DA8 https://t.co/CcwxAZP4ZR

Aug 31, 2022 · 7 likes · 2 shares · 4,902 followers View post →