Neurology November 2022 PMID 36195449

Morphologic and Molecular Patterns of Polymyositis With Mitochondrial Pathology and Inclusion Body Myositis.

Felix Kleefeld, Akinori Uruha, Anne Schänzer, Anna Nishimura, Andreas Roos, Udo Schneider, Hans H Goebel, Markus Schuelke, Katrin Hahn, Corinna Preusse, Werner Stenzel

Mentions

13
Peak: 5 in Apr 2023
across 3 sources since Nov 2022

Extended reach

213,316
potential audience

Total likes

37

Video views

2,907

Mentions per month

Nov 2022 – Jul 2025

Where it's discussed

  • X / Twitter9 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The social discussions demonstrate high interest by referencing detailed aspects of the study, such as divergent inflammatory responses in PM-Mito and IBM, with words like 'discuss' and 'analyze' indicating active engagement. The tone is professional and analytical, emphasizing the potential implications for diagnosis and treatment, which underscores the perceived importance of the research's contributions.

AgreementModerate agreement

Most discussions acknowledge the importance of the study, indicating general agreement with its findings and relevance.

InterestHigh interest

The discussions are highly engaging, as key participants actively analyze the article and its implications, demonstrating strong interest.

EngagementModerate engagement

Posts reference specific details like inflammatory markers and immune mechanisms, suggesting a moderate level of deep engagement.

ImpactModerate impact

The discussions highlight the significance of the findings for understanding myopathies, suggesting a potentially meaningful impact on medical research and practice.

Abstract in brief

  • This study aimed to understand the similarities and differences in the characteristics of polymyositis with mitochondrial pathology (PM-Mito) and sporadic inclusion body myositis (IBM), focusing on inflammatory responses and T-cell activity.
  • Researchers analyzed muscle biopsy samples from both patient groups and non-diseased controls, employing techniques like histopathology and qPCR to assess immune cell counts and gene expression.
  • Findings revealed that while PM-Mito and IBM shared many molecular traits, IBM exhibited significantly higher levels of certain inflammatory markers and immune cells, indicating divergent underlying mechanisms between the two conditions.

Top posts

Most liked on X and Bluesky
Neurology Journal
@GreenJournal · X

Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic and molecular patterns of #polymyositis with mitochondrial pathology and inclusion body myositis. Watch now: https://t.co/osW3qyA0q3 @BrighamWomens @harvardmed https://t.co/GZCqzHC22Z

Apr 7, 2023 · 12 likes · 5 shares · 98,155 followers View post →
Neurology Journal
@GreenJournal · X

Neurology® Video Journal Club: Drs. Anthony A. Amato and Paloma Gonzalez Perez discuss an article published in Neurology on morphologic and molecular patterns of PM-Mito and IBM. Watch now: https://t.co/30pX7IS1br Article: https://t.co/lVNfnoUNGI #NeuroTwitter https://t.co/37D2mqugDJ

Jan 5, 2024 · 11 likes · 98,155 followers View post →
Mari Carmen Porres
@LaPorres · X

RT @GreenJournal: Neurology® Video Journal Club: Drs. Anthony A. Amato and Paloma Gonzalez Perez discuss an article published in Neurology…

Jan 6, 2024 · 10,668 followers View post →
Giovanni Di Liberto
@DiLibertoMD · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Apr 8, 2023 · 5 shares · 1,213 followers View post →
Dataemia
@Dataemia · X

Morphologic and Molecular Patterns of Polymyositis With Mitochondrial Pathology and Inclusion Body Myositis - https://t.co/0T2btw837B

Nov 15, 2022 · 967 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Apr 8, 2023 · 5 shares · 545 followers View post →

All mentions

Sibz
@SibzSiba · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Jul 26, 2025 · 5 shares · 205 followers View post →
Mari Carmen Porres
@LaPorres · X

RT @GreenJournal: Neurology® Video Journal Club: Drs. Anthony A. Amato and Paloma Gonzalez Perez discuss an article published in Neurology…

Jan 6, 2024 · 10,668 followers View post →
Neurology Journal
@GreenJournal · X

Neurology® Video Journal Club: Drs. Anthony A. Amato and Paloma Gonzalez Perez discuss an article published in Neurology on morphologic and molecular patterns of PM-Mito and IBM. Watch now: https://t.co/30pX7IS1br Article: https://t.co/lVNfnoUNGI #NeuroTwitter https://t.co/37D2mqugDJ

Jan 5, 2024 · 11 likes · 98,155 followers View post →
NeuroMD
@lauraalonsomm · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Apr 9, 2023 · 5 shares · 115 followers View post →
Giovanni Di Liberto
@DiLibertoMD · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Apr 8, 2023 · 5 shares · 1,213 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @GreenJournal: Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic…

Apr 8, 2023 · 5 shares · 545 followers View post →
Neurology Journal
@GreenJournal · X

Neurology Video Journal Club: Dr. Steven Greenberg and Dr. Erika Williams discuss an article in Neurology on morphologic and molecular patterns of #polymyositis with mitochondrial pathology and inclusion body myositis. Watch now: https://t.co/osW3qyA0q3 @BrighamWomens @harvardmed https://t.co/GZCqzHC22Z

Apr 7, 2023 · 12 likes · 5 shares · 98,155 followers View post →
Dataemia
@Dataemia · X

Morphologic and Molecular Patterns of Polymyositis With Mitochondrial Pathology and Inclusion Body Myositis - https://t.co/0T2btw837B

Nov 15, 2022 · 967 followers View post →
Shiva Gopal Vasishta
@ShivaVasishta · X

Morphologic and Molecular Patterns of Polymyositis With Mitochondrial Pathology and Inclusion Body Myositis https://t.co/Evy52IC2nD #neurology #doctors #medtwitter #medical #medicinenews #healthcare

Nov 14, 2022 · 336 followers View post →