Endoscopy April 2023 PMID 36216266

Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study.

Hideki Ishikawa, Masayoshi Yamada, Yasushi Sato, Shinji Tanaka, Chino Akiko, Masahiro Tajika, Hisashi Doyama, Tetsuji Takayama, Yoshio Ohda, Takahiro Horimatsu, Yasushi Sano, Kohji Tanakaya, Hiroaki Ikematsu, Yoshihisa Saida, Hideyuki Ishida

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Mentions

8
Peak: 4 in Apr 2023
across 3 sources since Oct 2022

Extended reach

27,640
potential audience

Total likes

27

Video views

131

Mentions per month

Oct 2022 – Apr 2023

Where it's discussed

  • X / Twitter5 posts
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone reflects cautious optimism, with comments highlighting the potential of intensive endoscopic resection to delay or avoid colectomy, such as phrases like 'downstaging' and 'delay or avoid surgery,' which emphasize clinical significance. Some posts express curiosity about long-term outcomes, indicating moderate engagement and interest, while the focus on patient management implies a meaningful impact on future treatment approaches.

AgreementModerate agreement

Most discussions recognize the potential benefits of the endoscopic approach to delay surgery, aligning with the study's optimistic findings.

InterestModerate interest

Participants show moderate curiosity, focusing on how the method might change management and reduce surgical rates.

EngagementModerate engagement

Comments reference specific study details and raise questions about long-term risks, indicating thoughtful involvement.

ImpactModerate impact

The discussions suggest the article's findings could influence clinical practices and decision-making in managing FAP patients.

Abstract in brief

  • The study investigates whether intensive endoscopic removal of polyps (IDP) can effectively reduce the need for colectomy in patients with familial adenomatous polyposis (FAP), especially among young patients hesitant or refusing surgery.
  • Conducted at 22 centers, it included 222 patients, mostly those who hadn't had prior colectomy; results showed that about 95% of patients avoided colectomy over 5 years with this approach, suggesting it could be a viable way to manage FAP without immediate surgery.
  • However, the study notes that while IDP may help control polyp burden in mild to moderate FAP cases, a longer-term follow-up might reveal the eventual need for colectomy in many patients, indicating that IDP might not fully replace traditional surgical treatment over time.

Top posts

Most liked on X and Bluesky
Endoscopy Journal
@endoscopyjrnl · X

Familial adenomatous polyposis: intensive downstaging colorectal polypectomy to delay or avoid colectomy - a multicenter prospective interventional study Find more: https://t.co/Qd51nbPhOA Ishikawa Hideki et al. Intensive endoscopic resection for downstaging of polyp burden... https://t.co/TTLVS27Gz9

Apr 12, 2023 · 18 likes · 2 shares · 11,559 followers View post →
Kevin Monahan
@kevinjmonahan · X

Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis …. But does it reduce cancer risk…? https://t.co/qd1ki3lI6t

Oct 11, 2022 · 4 likes · 3,207 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

#AuthorCommentary Michihiro Mutoh & Hideki Ishikawa on "Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter..." Watch here: https://t.co/rPzYhjoXvf See more: https://t.co/Qd51nbPPE8

Apr 17, 2023 · 2 likes · 11,535 followers View post →
mowafy Jr.
@_Scholes__ · X

RT @endoscopyjrnl: Familial adenomatous polyposis: intensive downstaging colorectal polypectomy to delay or avoid colectomy - a multicenter…

Apr 12, 2023 · 2 shares · 631 followers View post →

All mentions

Endoscopy Journal
@endoscopyjrnl · X

#AuthorCommentary Michihiro Mutoh & Hideki Ishikawa on "Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter..." Watch here: https://t.co/rPzYhjoXvf See more: https://t.co/Qd51nbPPE8

Apr 17, 2023 · 2 likes · 11,535 followers View post →
mowafy Jr.
@_Scholes__ · X

RT @endoscopyjrnl: Familial adenomatous polyposis: intensive downstaging colorectal polypectomy to delay or avoid colectomy - a multicenter…

Apr 12, 2023 · 2 shares · 631 followers View post →
Ramiro Carreño Macián #NiHeroesNiMartires
@med020064 · X

RT @endoscopyjrnl: Familial adenomatous polyposis: intensive downstaging colorectal polypectomy to delay or avoid colectomy - a multicenter…

Apr 12, 2023 · 2 shares · 566 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

Familial adenomatous polyposis: intensive downstaging colorectal polypectomy to delay or avoid colectomy - a multicenter prospective interventional study Find more: https://t.co/Qd51nbPhOA Ishikawa Hideki et al. Intensive endoscopic resection for downstaging of polyp burden... https://t.co/TTLVS27Gz9

Apr 12, 2023 · 18 likes · 2 shares · 11,559 followers View post →
Kevin Monahan
@kevinjmonahan · X

Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis …. But does it reduce cancer risk…? https://t.co/qd1ki3lI6t

Oct 11, 2022 · 4 likes · 3,207 followers View post →