February 2023 PMID 36223558

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small-Cell Lung Cancer in CheckMate 227.

Julie R Brahmer, Jong-Seok Lee, Tudor-Eliade Ciuleanu, Reyes Bernabe Caro, Makoto Nishio, Laszlo Urban, Clarisse Audigier-Valette, Lorena Lupinacci, Randeep Sangha, Adam Pluzanski, Jacobus Burgers, Mauricio Mahave, Samreen Ahmed, Adam J Schoenfeld, Luis G Paz-Ares

Download social card

Mentions

62
Peak: 19 in Oct 2022
across 6 sources since Jun 2022

Extended reach

307,799
potential audience

Total likes

185

Video views

21,864

Mentions per month

Jun 2022 – Feb 2025

Where it's discussed

  • X / Twitter42 posts
  • News8 articles
  • Blogs6 articles
  • YouTube2 videos
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Discussions around this article use confident and precise language, such as 'confirms its superiority' and 'supports nivolumab plus ipilimumab as effective,' reflecting strong agreement. The tone and focus on detailed survival rates and clinical implications suggest high interest, deep engagement, and recognition of substantial impact on lung cancer treatment paradigms.

AgreementStrong agreement

Many discussions highlight positive outcomes and endorse immunotherapy as a superior option, with phrases like 'confirms its superiority' and 'supports nivolumab plus ipilimumab as effective,' indicating strong consensus.

InterestHigh interest

Posts reflect high curiosity through keywords like 'significant improvements,' 'five-year survival,' and references to detailed data, suggesting strong relevance and engagement.

EngagementHigh engagement

Several posts delve into specifics, such as 5-year survival rates and PD-L1 status, and include citations of study presentations, demonstrating deep analysis and active participation.

ImpactHigh impact

The discussions emphasize the potential for changing clinical practice, with remarks that the findings 'support' and 'confirm' the effectiveness of these treatments, indicating they perceive meaningful influence on future oncology approaches.

Top posts

Most liked on X and Bluesky
レ点
@m0370 · X

肺癌イピニボのCheckMate-227。これ見るとPD-L1<1%ってのは抗PD-1抗体にとっては不利な腫瘍だが、抗CTLA-4抗体はむしろ低PD-L1という逆境を乗り越える力を抗PD-1抗体に与える感じだな。やっぱ食道癌で「PD-L1陽性はイピニボ」という論調がしばしば出るのは変に感じる。 /JCO https://t.co/QmaaXufJx4

Oct 20, 2022 · 13 likes · 1 share · 28,813 followers View post →
Journal of Clinical Oncology
@JCO_ASCO · X

Jun 23, 2023 · 10 likes · 8 shares · 54,592 followers View post →
Journal of Clinical Oncology
@JCO_ASCO · X

Oct 28, 2022 · 8 likes · 9 shares · 54,592 followers View post →
Vivek Subbiah, MD
@VivekSubbiah · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/Hp7wLnX7uy

Feb 20, 2023 · 6 likes · 38,821 followers View post →
Masahiro Torasawa, MD. PhD.
@M_Torasawa · X

②CheckMate227試験(Nivo+Ipi vs Chemo)

Aug 26, 2024 · 6 likes · 2,440 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/Zip1enlhem

Feb 17, 2023 · 4 likes · 623 followers View post →

All mentions

シンノスケ
@simplechart111 · X

RT @m0370: 肺癌イピニボのCheckMate-227。これ見るとPD-L1<1%ってのは抗PD-1抗体にとっては不利な腫瘍だが、抗CTLA-4抗体はむしろ低PD-L1という逆境を乗り越える力を抗PD-1抗体に与える感じだな。やっぱ食道癌で「PD-L1陽性はイピニボ」と…

Feb 28, 2025 · 1 share · 487 followers View post →
Masahiro Torasawa, MD. PhD.
@M_Torasawa · X

②CheckMate227試験(Nivo+Ipi vs Chemo)

Aug 26, 2024 · 6 likes · 2,440 followers View post →
bet9 优德体育 足球 速8体育 彩金 江山美景图 彩娱乐 AB视讯
@JulieBrahmer · X

RT @JCO_ASCO:

Jun 29, 2023 · 8 shares · 1,644 followers View post →
Eileen M O’Reilly
@EileenMOReilly · X

RT @JCO_ASCO:

Jun 25, 2023 · 8 shares · 6,342 followers View post →
Sheyda Abdullaeva
@SheydaDoc · X

RT @JCO_ASCO:

Jun 24, 2023 · 8 shares · 108 followers View post →
Mayer
@Mayer46231196 · X

RT @JCO_ASCO:

Jun 24, 2023 · 8 shares · 164 followers View post →
YasarHammor
@YasarHammor · X

RT @JCO_ASCO:

Jun 23, 2023 · 8 shares · 509 followers View post →
Cristina Zannori
@CristinaZ2022 · X

RT @JCO_ASCO:

Jun 23, 2023 · 8 shares · 40 followers View post →
tomisuke
@nextommysuke · X

RT @JCO_ASCO:

Jun 23, 2023 · 8 shares · 918 followers View post →
Journal of Clinical Oncology
@JCO_ASCO · X

Jun 23, 2023 · 10 likes · 8 shares · 54,592 followers View post →
Journal of Clinical Oncology
@JCO_ASCO · X

Jun 15, 2023 · 1 like · 54,592 followers View post →
Johan Pluvy
@johanpluvy · X

RT @dipeshuprety4: CheckMate-227: 5-year OS rates were 24% and 19% for PD-L1 ≥ 1% and PD-L1 < 1% with Nivo-Ipi https://t.co/BkOe3chj3g

Mar 12, 2023 · 1 share · 121 followers View post →
Dipesh Uprety MD FACP
@DipeshUpretyMD · X

CheckMate-227: 5-year OS rates were 24% and 19% for PD-L1 ≥ 1% and PD-L1 < 1% with Nivo-Ipi https://t.co/BkOe3chj3g

Mar 12, 2023 · 2 likes · 1 share · 1,620 followers View post →
H. Zhao
@zhao_h · X

RT @cancer_evolve: LUNG: first line chemo-free immunotherapy treatment has delivered clinically meaningful improvements in 5 year survival…

Mar 7, 2023 · 1 share · 65 followers View post →
Cancer_Evolve
@cancer_evolve · X

LUNG: first line chemo-free immunotherapy treatment has delivered clinically meaningful improvements in 5 year survival rates, irrespective of PDL1 status or histology (adeno vs squamous). https://t.co/cZVYfjk1Zr

Feb 27, 2023 · 1 like · 1 share · 369 followers View post →
Vivek Subbiah, MD
@VivekSubbiah · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/Hp7wLnX7uy

Feb 20, 2023 · 6 likes · 38,821 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/Zip1enlhem

Feb 17, 2023 · 4 likes · 623 followers View post →
INDoximity
@indoximity · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/xQl0Bdc25W #Oncology

Feb 16, 2023 · 832 followers View post →
Dipesh Uprety MD FACP
@DipeshUpretyMD · X

6. 5-yr update of CheckMate-227: With Nivo plus Ipilimumab, 5-yr OS rates ➡️ 24% for PD-L1 ≥ 1% ➡️19% for PD-L1 < 1% https://t.co/t5OQsjq1mN

Dec 14, 2022 · 1 like · 1,620 followers View post →
alberto ravaioli
@RavaioliAlberto · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/UmMf8PN7bi

Nov 10, 2022 · 873 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/bFnS8VinIg

Nov 9, 2022 · 1 like · 623 followers View post →
FarmaOnco
@FarmaOnco · X

RT @gedefo_sefh: Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–…

Nov 9, 2022 · 1 share · 2,633 followers View post →
GEDEFO
@gedefo_sefh · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non–Small-Cell Lung Cancer in CheckMate 227 https://t.co/EEwXbsOux9

Nov 8, 2022 · 1 like · 1 share · 5,434 followers View post →
Shannon Westin, MD, MPH, FASCO
@ShannonWestin · X

RT @JCO_ASCO:

Oct 29, 2022 · 9 shares · 5,308 followers View post →
Sergio
@sergiomejiaonco · X

RT @MLPOncoData: Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-…

Oct 29, 2022 · 1 share · 81 followers View post →
takaaki
@odatka2 · X

RT @JCO_ASCO:

Oct 29, 2022 · 9 shares · 1 followers View post →
Oxana Shatkovskaya
@OShatkovskaya · X

RT @JCO_ASCO:

Oct 29, 2022 · 9 shares · 18 followers View post →
OncoNetwork
@onconetwork · X

RT @JCO_ASCO:

Oct 29, 2022 · 9 shares · 36 followers View post →
Ahmed Tayel
@AhmedTayel13 · X

RT @JCO_ASCO:

Oct 28, 2022 · 9 shares · 363 followers View post →
Monica Duran
@MonicaYDuran · X

RT @JCO_ASCO:

Oct 28, 2022 · 9 shares · 10 followers View post →
MLP Oncología
@MLPOncoData · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small Cell Lung Cancer in CheckMate 227 https://t.co/6c8U4Zx33V

Oct 28, 2022 · 1 like · 1 share · 705 followers View post →
Ricardo Arteaga
@mcricardoa · X

RT @JCO_ASCO:

Oct 28, 2022 · 9 shares · 30 followers View post →
Antonio Torres
@viniciu_antonio · X

RT @JCO_ASCO:

Oct 28, 2022 · 9 shares · 340 followers View post →
Journal of Clinical Oncology
@JCO_ASCO · X

Oct 28, 2022 · 8 likes · 9 shares · 54,592 followers View post →
ALCASE Italia
@ALCASEItalia · X

Confermata ancora una volta (con dati, come si dice, "maturi") la superiorità dell'immunoterapia (NIVOLUMAB + IPILIMUMAB) rispetto alla chemio nel trattamento di prima linea del cancro al polmone non a piccole cellule metastatico. https://t.co/FTVVem1IKK

Oct 23, 2022 · 319 followers View post →
Vitor Moutinho, MD, MSc
@vitor__moutinho · X

Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small Cell Lung Cancer in CheckMate 227. https://t.co/WFfWcoBguG @JCO_ASCO https://t.co/vA5ENFe3Ui

Oct 21, 2022 · 1 like · 5,694 followers View post →
レ点
@m0370 · X

肺癌イピニボのCheckMate-227。これ見るとPD-L1<1%ってのは抗PD-1抗体にとっては不利な腫瘍だが、抗CTLA-4抗体はむしろ低PD-L1という逆境を乗り越える力を抗PD-1抗体に与える感じだな。やっぱ食道癌で「PD-L1陽性はイピニボ」という論調がしばしば出るのは変に感じる。 /JCO https://t.co/QmaaXufJx4

Oct 20, 2022 · 13 likes · 1 share · 28,813 followers View post →
ACIR
@ACIR_org · X

Oct 17, 2022 · 2 likes · 3,074 followers View post →
Paz-Ares's Lab
@PazAresLab · X

A recent study by @JulieBrahmer et colleagues supports nivolumab plus ipilimumab as an effective first-line treatment for patients with metastatic NSCLC https://t.co/8PeC14EZRM

Oct 17, 2022 · 1,081 followers View post →
星良孝 Yoshitaka Hoshi
@yoshitakahoshi · X

https://t.co/cIgJJKyIsF

Oct 17, 2022 · 2 likes · 8,184 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small Cell Lung Cancer in CheckMate 227 https://t.co/X9YmNarPdb #lungcancer #oncology https://t.co/Ryyfq0sIDn

Oct 12, 2022 · 891 followers View post →
IDEOlogy Health
@IDEOlogyHealth · X

Join @JulieBrahmer presenting results from CheckMate 227: Five-year survival outcomes with nivolumab plus ipilimumab versus chemotherapy as first-line treatment for metastatic non–small cell #lungcancer @bmsnews #ASCO22 Hall A starting 8 am

Jun 6, 2022 · 616 followers View post →