October 2022 PMID 36240095

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.

Thomas Jaworek, Huichun Xu, Brady J Gaynor, John W Cole, Kristiina Rannikmae, Tara M Stanne, Liisa Tomppo, Vida Abedi, Philippe Amouyel, Nicole D Armstrong, John Attia, Steven Bell, Oscar R Benavente, Giorgio B Boncoraglio, Adam Butterworth

Mentions

281
Peak: 19 in Sep 2022
across 6 sources since Aug 2022

Extended reach

564,485
potential audience

Total likes

222

Video views

8,738

Mentions per month

Aug 2022 – Jun 2025

Where it's discussed

  • News208 articles
  • X / Twitter51 posts
  • Blogs16 articles
  • Facebook3 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Several discussions delve into the specific findings mentioned in the article, such as the increased risk of early-onset stroke among individuals with type A blood. Posts use terminology like 'significant links' and 'higher genetic propensity,' reflecting urgency and importance in the context of genetic research on health. The tone ranges from informative to alarmed about the implications for young individuals, enhancing the overall perception of potential impact.

AgreementModerate agreement

Many discussions reflect a general support for the findings of the publication, particularly around the genetic connections to early-onset ischemic stroke.

InterestHigh interest

There is a high level of curiosity shown by users, especially regarding the implications of blood types on stroke risk.

EngagementModerate engagement

While some posts engage in a surface-level mention of the research, there are instances of deeper discussions on the implications of specific genetic factors.

ImpactHigh impact

Overall, the perception is that the findings could significantly influence understanding and prevention strategies for early-onset ischemic stroke.

Abstract in brief

  • The study investigates genetic variants linked to early-onset ischemic stroke (EOS) in individuals aged 18-59, contrasting with previous research focused on late-onset stroke (LOS).
  • Researchers conducted a meta-analysis involving 16,730 EOS cases and 599,237 controls to identify significant genetic associations and compared results between EOS and LOS.
  • Findings include two genetic variants associated with blood subgroups that show a stronger connection to EOS than LOS, indicating that genetic factors promoting blood clotting are particularly influential in early-onset cases.

Top posts

Most liked on X and Bluesky
UM Population Studies Center
@UM_PSC · X

A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke. @JFaul99 and David R. Weir of @UM_PSC and @UM_SRC co-author: https://t.co/6PTd9OByFq https://t.co/OsdAKRt3uq

Sep 6, 2022 · 10 likes · 5 shares · 3,135 followers View post →
Neurology Journal
@GreenJournal · X

Finish the year strong with Neurology journal's top read articles of 2022! Read #3—Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke: https://t.co/suAqeVbXgq #NeuroTwitter #Neurology https://t.co/tQ1BjSPgXY

Dec 29, 2022 · 9 likes · 2 shares · 98,154 followers View post →
Neurology Journal
@GreenJournal · X

Contribution of Common #Genetic Variants to Risk of Early-Onset Ischemic #Stroke: https://t.co/dIfN0prDWP #NeuroTwitter https://t.co/6XNhk80epo

Oct 23, 2022 · 9 likes · 1 share · 98,154 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/bYqhZnPPAv

Sep 1, 2022 · 9 likes · 1 share · 79,166 followers View post →
AshuJadhav
@AshuPJadhav · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/a7wRgW7A25

Aug 31, 2022 · 6 likes · 4 shares · 17,544 followers View post →
Reiner 
@erlesen · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/8DZW0CoIGn Your Blood Type May Affect Your Risk of an Early Stroke, Research Reveals https://t.co/Lig4S8JhCj

Jan 2, 2023 · 5 likes · 1 share · 7,860 followers View post →

All mentions

Kelvin R.
@Kelvin_ramlo · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke | Neurology https://t.co/vCQm2O4zVn

Jun 26, 2025 · 103 followers View post →
Longevity
@LongevityTao · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke | Neurology https://t.co/LosJ91xPjg

Jun 25, 2025 · 329 followers View post →
رمزي الزهراني
@Makkitter · X

@OKAZ_online هل هي هذه

Mar 13, 2025 · 12,685 followers View post →
Derfel-ap-arthur
@ap_derfel · X

Des découvertes montrent des liens significatifs entre les sous-groupes sanguins O1 & A1 et les AVC précoces (EOS), avec des effets plus marqués qu’en cas d’AVC tardifs (LOS). #Génétique #RechercheAVC https://t.co/hVZGVgRQxu

Jan 4, 2025 · 437 followers View post →
心理学解説bot
@kruchoro · X

血液型がA型の人は、若いうちに脳卒中や血栓症にかかるリスクが他の血液型の人よりも高い Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/efpjDDZh1a

Oct 16, 2024 · 6,443 followers View post →
Marc Veldhoen
@marcveld.bsky.social · Bluesky

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke This is a meta-analysis of genome-wide association studies of early-onset stroke (EOS), in ages 18–59 years. Blood group A had a higher genetic propensity for thrombosis. www.neurology.org/do... 4/5

Oct 10, 2024 · 1 like · 1 share View post →
Razaz Felemban
@razazfelemban · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke | Neurology. Individuals with type A blood have a 16% higher risk for early-onset stroke (EOS) than those with other blood types! https://t.co/549wJscH4r

Feb 12, 2023 · 1,121 followers View post →
Roger Blackwell
@rogerablackwell · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/W4PXsEq6aY

Feb 8, 2023 · 2,307 followers View post →
Luis Mochizuki
@mochizukil · X

É de outubro/22, mas continua interessante! Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/V8oMjpVfeX

Feb 8, 2023 · 173 followers View post →
uz_tw
@uz_tw · X

論文はコチラから。(neurologyに掲載) Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/G05KpWzfZt

Jan 27, 2023 · 1,273 followers View post →
hummy
@m_hummy · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke | Neurology https://t.co/3nhEfZsSSG

Jan 3, 2023 · 29 followers View post →
Reiner 
@erlesen · X

RT @erlesen: Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/8DZW0CoIGn Your Blood Type May Aff…

Jan 3, 2023 · 1 share · 7,860 followers View post →
Reiner 
@erlesen · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/8DZW0CoIGn Your Blood Type May Affect Your Risk of an Early Stroke, Research Reveals https://t.co/Lig4S8JhCj

Jan 2, 2023 · 5 likes · 1 share · 7,860 followers View post →
Roger Blackwell
@rogerablackwell · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/W4PXsEq6aY

Jan 2, 2023 · 2,307 followers View post →
FAMA
@apoyarenas · X

RT @GreenJournal: Finish the year strong with Neurology journal's top read articles of 2022! Read #3—Contribution of Common Genetic Varian…

Dec 30, 2022 · 2 shares · 14 followers View post →
Mistletoe US
@mistletoeus · X

RT @GreenJournal: Finish the year strong with Neurology journal's top read articles of 2022! Read #3—Contribution of Common Genetic Varian…

Dec 29, 2022 · 2 shares · 2,908 followers View post →
Neurology Journal
@GreenJournal · X

Finish the year strong with Neurology journal's top read articles of 2022! Read #3—Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke: https://t.co/suAqeVbXgq #NeuroTwitter #Neurology https://t.co/tQ1BjSPgXY

Dec 29, 2022 · 9 likes · 2 shares · 98,154 followers View post →
ASEMEVE
@asemeve · X

RT @ESVM_: Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke. Individuals with type A blood have a 16% higher…

Nov 14, 2022 · 1 share · 476 followers View post →
TICR
@TICR4 · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke. Individuals with type A blood have a 16% higher risk for early-onset stroke (EOS) than those with other blood types https://t.co/WSsfaECvL2

Nov 13, 2022 · 305 followers View post →
European Society of Vascular Medicine
@ESVM_ · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke. Individuals with type A blood have a 16% higher risk for early-onset stroke (EOS) than those with other blood types https://t.co/MbiR7HLMjS

Nov 13, 2022 · 1 like · 1 share · 1,300 followers View post →
Yan-Ran Li
@ynrnl1 · X

RT @GreenJournal: Contribution of Common #Genetic Variants to Risk of Early-Onset Ischemic #Stroke: https://t.co/dIfN0prDWP #NeuroTwitter h…

Oct 25, 2022 · 1 share · 37 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Contribution of Common #Genetic Variants to Risk of Early-Onset Ischemic #Stroke #NeuroTwitter: https://t.co/5M5bvaEdIu https://t.co/F0ruDWCj60

Oct 24, 2022 · 24,143 followers View post →
Neurology Journal
@GreenJournal · X

Contribution of Common #Genetic Variants to Risk of Early-Onset Ischemic #Stroke: https://t.co/dIfN0prDWP #NeuroTwitter https://t.co/6XNhk80epo

Oct 23, 2022 · 9 likes · 1 share · 98,154 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke - AAN Neurology via BrainSights for iOS https://t.co/fM6hzMRWuo

Oct 17, 2022 · 312 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke - AAN Neurology via BrainSights for iOS https://t.co/fM6hzMzNgg

Oct 17, 2022 · 312 followers View post →
Shiva Gopal Vasishta
@ShivaVasishta · X

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke https://t.co/EaCKo8RGmi #neurology #doctors #medtwitter #medical #medicinenews #healthcare

Oct 17, 2022 · 336 followers View post →
BibliotecaHUVH
@BibliotecaHUVH · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/fNqoHtyE1T #hvhebron #psiq @GreenJournal

Oct 17, 2022 · 2,312 followers View post →
Dennis Lal
@LalDennis · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/diVXQOblvk https://t.co/5YWSTw9mhu

Oct 14, 2022 · 3,315 followers View post →
Oxford Psychiatry
@OxPsychiatry · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/VYzwUzSIHM

Oct 14, 2022 · 22,100 followers View post →
PRS papers
@PRS_pubmed · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/O5hcGTB0NZ

Oct 14, 2022 · 400 followers View post →
UVA Science Pubs
@UvaScience_Pubs · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/4kCyufvACs https://t.co/OPUr24v74I

Oct 14, 2022 · 1 like · 258 followers View post →
Reiner 
@erlesen · X

RT @erlesen: Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/9q14iD9LBM Schlaganfall-Risiko bei…

Sep 26, 2022 · 1 share · 7,860 followers View post →
Reiner 
@erlesen · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/9q14iD9LBM Schlaganfall-Risiko bei jungen Menschen: Eine Blutgruppe besonders gefährdet https://t.co/6FQEYb25vF Wer die Blutgruppe 0 vorwies, hatte demnach ein geringeres Erkrankungsrisiko

Sep 25, 2022 · 5 likes · 1 share · 7,860 followers View post →
UM SRC
@UM_SRC · X

Jessica Faul, Jennifer A. Smith, David Weir, et al. sought to identify the contribution of common genetic variants to risk of early onset ischemic stroke https://t.co/srdWxcuxcZ

Sep 8, 2022 · 1,950 followers View post →
理学療法士_海津陽一 Ph.D.
@copellist · X

■ Ref info: Jaworek, Thomas, et al. "Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke." Neurology (2022). ■ Ref link: https://t.co/MFXBAUqB15 ■ Today’s full:https://t.co/UlrOCOKUAO

Sep 7, 2022 · 10,752 followers View post →
Jas Wall
@jaz_walker · X

RT @UM_PSC: A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke…

Sep 6, 2022 · 5 shares · 123 followers View post →
めじぇど。
@49_FufuKUkuu · X

ふーん。 Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke | Neurology https://t.co/D74RbuIryJ

Sep 6, 2022 · 3 likes · 7,892 followers View post →
Neurology Journal
@GreenJournal · X

RT @UM_PSC: A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke…

Sep 6, 2022 · 5 shares · 98,154 followers View post →
UM SRC
@UM_SRC · X

RT @UM_PSC: A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke…

Sep 6, 2022 · 5 shares · 1,950 followers View post →
U-M ISR
@umisr · X

RT @UM_PSC: A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke…

Sep 6, 2022 · 5 shares · 5,828 followers View post →
UM Population Studies Center
@UM_PSC · X

A new GWAS study in @GreenJournal identifies the contribution of common genetic variants to risk of early onset ischemic stroke. @JFaul99 and David R. Weir of @UM_PSC and @UM_SRC co-author: https://t.co/6PTd9OByFq https://t.co/OsdAKRt3uq

Sep 6, 2022 · 10 likes · 5 shares · 3,135 followers View post →
Atsushi Oshio / 小塩真司
@oshio_at · X

これですね。ゲノムワイド関連分析のメタ分析。 Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/Lq5WV1Nfdm

Sep 6, 2022 · 8,700 followers View post →
Fradi Frad Dreizehn
@frad_fradi · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke | Neurology https://t.co/4NFeJGj4sO

Sep 4, 2022 · 2,453 followers View post →
Tiedonhaluinen
@Tiedonhalu · X

Veriryhmä A altistaa hiukan aivoinfarktille. Kas kummaa, myös #covid tykkää noista ihmisistä. https://t.co/snIXkxTwbS

Sep 3, 2022 · 229 followers View post →
Viljami
@tiedonjanoa · X

Veriryhmä A alttiimpi aivoinfarktille. (#covid riski myös suurempi, aiemmin todettu) https://t.co/bnEh66xzgm

Sep 3, 2022 · 182 followers View post →
ong beng hooi
@ongbenghooi1 · X

RT @AshuPJadhav: Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/a7wRgW7A25

Sep 1, 2022 · 4 shares · 545 followers View post →
Dr Anthony Martin
@AMAinsight · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke | Neurology https://t.co/PFsIkidz0D

Sep 1, 2022 · 913 followers View post →
青柳
@FBWM8888 · X

RT @ichiipsy: Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/bYqhZnPPAv

Sep 1, 2022 · 1 share · 732 followers View post →
octavio
@dontavo66 · X

RT @AshuPJadhav: Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/a7wRgW7A25

Sep 1, 2022 · 4 shares · 329 followers View post →
いっちー@バーチャル精神科医
@ichiipsy · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/bYqhZnPPAv

Sep 1, 2022 · 9 likes · 1 share · 79,166 followers View post →
CESAR ALVES
@cesaralvesneuro · X

RT @AshuPJadhav: Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/a7wRgW7A25

Aug 31, 2022 · 4 shares · 1,572 followers View post →
AshuJadhav
@AshuPJadhav · X

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke https://t.co/a7wRgW7A25

Aug 31, 2022 · 6 likes · 4 shares · 17,544 followers View post →