Mol Diagn Ther November 2022 PMID 36251245

Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds.

Alex du Rand, John M T Hunt, Vaughan Feisst, Hilary M Sheppard

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Mentions

Peak: 4 in Oct 2022

across 2 sources since Oct 2022

Extended reach

6,984

potential audience

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Video views

2,282

Mentions per month

Oct 2022 – Jun 2024

Where it's discussed

X / Twitter4 posts
YouTube2 videos

AI synopsis

What people are saying

The social discussions reflect a positive and curious tone, with phrases like 'wonder no more' and mentions of 'best ways to engineer skin' indicating genuine interest. The posts support the article's importance in advancing treatment options for fragile skin conditions, emphasizing its potential impact on future therapies.

AgreementModerate agreement

Most discussions acknowledge the importance and relevance of the review, showing overall support for the research focus.

InterestHigh interest

Posts demonstrate a high level of curiosity and eagerness to learn, highlighted by phrases like 'wonder no more' and direct questions about innovative skin engineering.

EngagementModerate engagement

The discussions contain references to the article's content and its significance, but lack detailed analysis or critical evaluation, indicating moderate engagement.

ImpactModerate impact

The discourse suggests that the publication could influence future research and treatment approaches, though it remains at an introductory level.

Abstract in brief

This review discusses the use of tissue-engineered skin substitutes (TESSs) for treating epidermolysis bullosa (EB), a severe skin disorder with no current cure that leads to fragile skin and poor wound healing.
TESSs are made from human skin cells and scaffolds, and they can be categorized based on cell types like keratinocytes (epidermal), fibroblasts (dermal), or both, with some being autologous (patient's own cells) to better mimic natural skin.
While epidermal TESSs have shown promise for long-term wound healing, their effectiveness varies among EB subtypes; ongoing research is now focusing on personalized, gene-corrected, autologous TESSs that could offer broader and more durable treatment options.

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All mentions

Tissue-Engineered Skin Substitutes for Treating Epidermolysis Bullosa

This review discusses the use of tissue-engineered skin substitutes for treating epidermolysis bullosa, a severe skin disorder with no current cure. These substitutes are made from human skin cells and scaffolds, with…

Saurabh Bhatia · Jun 8, 2024 1,442 views

Advances in Epidermolysis Bullosa Treatment: Tissue-Engineered Skin Therapies

This review discusses the use of tissue-engineered skin substitutes for treating epidermolysis bullosa, a severe skin disorder with no current cure that leads to fragile skin and poor wound healing. Ongoing research…

Saurabh Bhatia · Jun 8, 2024 840 views

Ciara Ramiah

@ciararamiah · X

RT @HilarySheppard9: I know you’ve been wondering ‘what’s the best way to engineer skin for people with fragile skin conditions?’ - well, w…

Oct 25, 2022 · 1 share · 16 followers View post →

Ivan Alfaro

@alfobioq · X

RT @DarioBalacco: Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds https://t.co/477OnyLYsY

Oct 19, 2022 · 1 share · 821 followers View post →

Dario Balacco, PhD

@DarioBalacco · X

Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds https://t.co/477OnyLYsY

Oct 19, 2022 · 5 likes · 1 share · 3,549 followers View post →

Hilary Sheppard

@HilarySheppard9 · X

I know you’ve been wondering ‘what’s the best way to engineer skin for people with fragile skin conditions?’ - well, wonder no more- read all about it here! https://t.co/alH2kmv3vR

Oct 18, 2022 · 3 likes · 1 share · 309 followers View post →