ACS Chem Neurosci November 2022 PMID 36283035

Alzheimer's Disease Prevention through Natural Compounds: Cell-Free, and Dissection of Hop ( L.) Multitarget Activity.

Alessandro Palmioli, Valeria Mazzoni, Ada De Luigi, Chiara Bruzzone, Gessica Sala, Laura Colombo, Chiara Bazzini, Chiara Paola Zoia, Mariagiovanna Inserra, Mario Salmona, Ivano De Noni, Carlo Ferrarese, Luisa Diomede, Cristina Airoldi

Mentions

93
Peak: 34 in Nov 2022
across 5 sources since Oct 2022

Extended reach

218,890
potential audience

Total likes

84

Video views

36

Mentions per month

Oct 2022 – Dec 2025

Where it's discussed

  • Facebook50 posts
  • X / Twitter35 posts
  • News4 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The overall tone indicates positive enthusiasm, highlighted by phrases like 'your hops may prevent Alzheimer's' and references to the research being a potential breakthrough, driven by words such as 'could help' and 'prevents.' The mixture of scientific references and casual mentions creates an atmosphere of curiosity and optimistic support, emphasizing the significance and possible societal impact of the findings.

AgreementModerate agreement

Most discussions express support and excitement for the potential of hops in preventing or treating Alzheimer's, indicating broad agreement with the publication’s findings.

InterestHigh interest

Posts demonstrate high interest by mentioning specific mechanisms, compounds, and potential practical applications like brewing beer as a preventive measure.

EngagementModerate engagement

Engagement is moderate; some posts reflect curiosity and support, but few go deeply into scientific details or critique, showing a general but not profound level of involvement.

ImpactModerate impact

The discussions suggest the publication could influence public perception and interest in natural compounds for neuroprotection, though concrete policy or clinical impacts are not clearly established.

Abstract in brief

  • The study explores the potential of natural compounds found in hops, a main ingredient in beer, to prevent Alzheimer's Disease by targeting key biochemical mechanisms like peptide aggregation and oxidative stress.
  • Researchers characterized four hop varieties (Cascade, Saaz, Tettnang, Summit) and tested their ability to reduce amyloid-beta aggregation, promote autophagy, and combat neurotoxicity using cell-based assays and advanced analytical techniques like NMR and MS metabolomics.
  • Key anti-Alzheimer's components identified in hops include feruloyl and coumaroylquinic acids, flavan-3-ol glycosides, and procyanidins, which could serve as natural multitarget agents for AD prevention.

Top posts

Most liked on X and Bluesky
Luna Sarcazio
@lunasarcazio · X

Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 57 likes · 18 shares · 1,911 followers View post →
Agingdoc
@agingdoc1 · X

Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity

Nov 21, 2022 · 11 likes · 2 shares · 43,372 followers View post →
Alessandro Crimi
@Dr_Alex_Crimi · X

Substantially the cure for #Alzheimer is hidden in #beer ;-) "Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity" https://t.co/GjMpWqSJRI https://t.co/AQ38o91peT

Nov 15, 2022 · 5 likes · 8,161 followers View post →
Charles Gordon
@princetongb · X

=> Your beer hops may prevent Alzheimer's =>Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/tJg8l6u8je

Jan 3, 2023 · 3 likes · 5,033 followers View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The paper in "ACS Chemical Neuroscience" the above "Inside Precision Medicine" article is based upon: “Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity” https://t.co/Hz5QDzA8oA

Nov 30, 2022 · 3 likes · 1 share · 4,369 followers View post →
George Dawson
@dawso007 · X

Open access: investigation of the antioxidant and antiamyloid effects of hop extract. NA beer is probably a better choice. https://t.co/zasmfmQHmz

Nov 23, 2023 · 1 like · 7,819 followers View post →

All mentions

Jarek Growin
@JarekGrowin · X

Dzisiaj kilka linków na temat wpływu chmielu na Alzheimera: https://t.co/kwU5Sh9gM2 https://t.co/YWF7AqmYKS https://t.co/OarhV0KE7d Podsumowując: można zapobiegać a nawet leczyć początki alzheimara wyciągiem z szyszek chmielowych.

Nov 14, 2024 View post →
George Dawson
@dawso007 · X

Open access: investigation of the antioxidant and antiamyloid effects of hop extract. NA beer is probably a better choice. https://t.co/zasmfmQHmz

Nov 23, 2023 · 1 like · 7,819 followers View post →
Woody Nist
@Woodynist · X

Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity (octobre 2022) https://t.co/ofMIWfqZTQ

Apr 20, 2023 · 1,311 followers View post →
Treventis
@Treventis_corp · X

#Hops have been found to hinder Aβ1–42 peptide aggregation and promote the clearance of misfolded and aggregated #proteins by upregulating autophagy preventing and mediating the biochemical mechanisms responsible for #Alzheimer’s #disease onset. https://t.co/kaaOD7URcE https://t.co/2VDxuOhhRp

Jan 16, 2023 · 1 like · 85 followers View post →
シゲチー@
@ShoRatio · X

ビール好きの同胞たちに朗報です https://t.co/zWl5jnc3fV

Jan 5, 2023 · 2,277 followers View post →
Charles Gordon
@princetongb · X

=> Your beer hops may prevent Alzheimer's =>Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/tJg8l6u8je

Jan 3, 2023 · 3 likes · 5,033 followers View post →
Charles Gordon
@princetongb · X

=> You beer hops may prevent Alzheimer's =>Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/tJg8l6uG8M

Jan 3, 2023 · 5,033 followers View post →
サイエンスあれこれ
@sarekore · X

使って調べたところ、ドキシサイクリンと同程度の神経保護活性を示しました。https://t.co/1v4htOITLg

Dec 31, 2022 · 942 followers View post →
John West
@JohnWest_JAWS · X

RT @AndrewW66619812: The paper in "ACS Chemical Neuroscience" the above "Inside Precision Medicine" article is based upon: “Alzheimer’s Di…

Nov 30, 2022 · 1 share · 25,796 followers View post →
Andy_Weeble_Weaver
@AndrewW66619812 · X

The paper in "ACS Chemical Neuroscience" the above "Inside Precision Medicine" article is based upon: “Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity” https://t.co/Hz5QDzA8oA

Nov 30, 2022 · 3 likes · 1 share · 4,369 followers View post →
Tim Storr
@storr_tim · X

Alzheimer's drug from Eisai and Biogen slows cognitive decline: https://t.co/P9uhF9tS1D Combine this with beer and we are onto something: https://t.co/4nsvt6kGmb

Nov 30, 2022 · 1 like · 680 followers View post →
Simône Silva
@ninasymony · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 22, 2022 · 18 shares · 113 followers View post →
CopperKettle
@Artyom_Yekat · X

RT @agingdoc1: Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulu…

Nov 22, 2022 · 2 shares · 382 followers View post →
yasmin
@girlwearsart · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 22, 2022 · 18 shares · 966 followers View post →
JURÍDICO DOS BRASILEIROS DA HYBE
@daemonitter · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 353 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @agingdoc1: Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulu…

Nov 21, 2022 · 2 shares · 32,588 followers View post →
Ericasjr
@Ericasjr2 · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 7 followers View post →
yBenihime ~ NeX Gen
@ybenihime · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 43 followers View post →
Terapeuta de pinscher
@DrPinscher · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 42 followers View post →
Caemorera
@Caemorera1 · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 22 followers View post →
Guegué Bailas
@guegueb · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 72 followers View post →
Willian Braga ❁
@neverping · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 328 followers View post →
Rodigo
@PoloRDG · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 155 followers View post →
vini
@viservano · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 692 followers View post →
BeLu ✨
@onlystarlight_ · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 177 followers View post →
Gabriela Bailas, PhD
@bibibailas · X

RT @lunasarcazio: Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 18 shares · 69,300 followers View post →
Luna Sarcazio
@lunasarcazio · X

Ai gente, sei lá sabe… cansa

Nov 21, 2022 · 57 likes · 18 shares · 1,911 followers View post →
Agingdoc
@agingdoc1 · X

Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity

Nov 21, 2022 · 11 likes · 2 shares · 43,372 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @physorg_com: Beer hops compounds could help protect against #Alzheimer'sdisease https://t.co/LyOlLD8fGD https://t.co/LjLiBpeXcZ

Nov 17, 2022 · 11 shares · 1,785 followers View post →
Alessandro Crimi
@Dr_Alex_Crimi · X

Substantially the cure for #Alzheimer is hidden in #beer ;-) "Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity" https://t.co/GjMpWqSJRI https://t.co/AQ38o91peT

Nov 15, 2022 · 5 likes · 8,161 followers View post →
carai calorina
@o_diariodecarol · X

@RafaelCdeSouza4 @choquei https://t.co/Tjov4ZUUqr Melhor?

Nov 15, 2022 · 343 followers View post →
dri
@AdriXbt · X

Será que o consumo de cerveja pode ajudar a prevenção da doença de Alzheimer ??? https://t.co/vy2hCgfVDm https://t.co/h2vadDCVIq

Nov 15, 2022 · 1 like · 399 followers View post →
Researching the Brain
@Brain_Database · X

#Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/oTLX8hLF3v

Nov 14, 2022 · 1,038 followers View post →
Autophagy Papers
@AutophagyPapers · X

Alzheimer's Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/5Mj5jnh5b0 https://t.co/KslzSvTuhP

Oct 26, 2022 · 1,706 followers View post →
Paperbirds_Neurology
@PaperbirdsN · X

New article: Alzheimer's Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/eU5NhUJImJ #alzheimers #neurology https://t.co/bPeTdbWhsy

Oct 25, 2022 · 452 followers View post →
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