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Front Nutr October 2022 PMID 36313077

Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.

Xiaoxia Li, Luwen Cui, Guilin Feng, Shengnan Yu, Guanglong Shao, Ningning He, Shangyong Li

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Mentions

4
Peak: 1 in Nov 2022
across 3 sources since Nov 2022

Extended reach

158,527
potential audience

Total likes

4,712

Video views

154,599

Mentions per month

Nov 2022 – Dec 2025

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts
  • News1 articles

AI synopsis

What people are saying

Several posts highlight the potential risks of collagen peptides for people with inflammatory conditions, using phrases like 'not suitable' and 'could worsen,' which reflect concern and caution. The tone remains mostly informative with occasional skepticism, indicating interest but not deep or widespread engagement with technical details or implications.

AgreementLow agreement

Most discussions acknowledge the research findings, but some express skepticism about the implications or question the methodology.

InterestModerate interest

The discussions show moderate interest, with few posts delving into the detailed mechanisms or broader impacts.

EngagementNeutral engagement

Post interactions suggest a casual overview rather than deep analysis, with minimal detailed debate.

ImpactNeutral impact

The overall influence of these discussions seems limited, mainly sharing the news without extensive exploration of consequences.

Abstract in brief

  • The study investigated the effects of collagen peptide (CP) on ulcerative colitis (UC) using a mouse model and found that CP supplementation worsened colitis symptoms by increasing inflammatory responses and disrupting gut microbiota.
  • CP was shown to promote M1 macrophage polarization, leading to heightened inflammation, suggesting that CP can activate immune cells that contribute to intestinal damage.
  • Overall, the findings indicate that marine-derived CP may not be suitable for patients with intestinal inflammation, as it could exacerbate the condition instead of providing benefits.]
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Top posts

Most liked on X and Bluesky
Frontiers - Nutrition
@FrontNutrition · X

New Research: Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization: Ulcerative colitis (UC) is an inflammatory bowel disease caused by mucosal immune system disorder, which has… https://t.co/yHUeQQH45k #Nutrition

Nov 19, 2022 · 3,919 followers View post →

All mentions

Frontiers - Nutrition
@FrontNutrition · X

New Research: Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization: Ulcerative colitis (UC) is an inflammatory bowel disease caused by mucosal immune system disorder, which has… https://t.co/yHUeQQH45k #Nutrition

Nov 19, 2022 · 3,919 followers View post →
5 Conditions Collagen Can Help Manage Naturally
News

doi:10.3389/fnut.2022.957391. Wang H. A review of the effects of collagen treatment in clinical studies. Polymers. 2021;13(22):3868. doi ...

Oct 23, 2025 View →