October 2022 PMID 36325189

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer's disease.

Xiaolan Liu, Meng Ye, Liang Ma

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Mentions

18
Peak: 6 in Nov 2022
across 4 sources since Oct 2022

Extended reach

127,297
potential audience

Total likes

40

Video views

470

Mentions per month

Oct 2022 – Apr 2024

Where it's discussed

  • X / Twitter11 posts
  • News3 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The overall tone reflects a positive acknowledgment of the article’s significance, with posts highlighting the role of autophagy and mitophagy in Alzheimer's and mentioning potential interventions like rapamycin. Words like 'emerging role' and phrases like 'translational implications' suggest a moderate but promising interest in linking cellular mechanisms to clinical advances.

AgreementModerate agreement

Most discussions acknowledge the importance of autophagy and mitophagy in understanding Alzheimer's pathology, showing general consensus.

InterestModerate interest

Participants show curiosity about the research, as evidenced by references to new mechanisms and potential treatments.

EngagementNeutral engagement

While some posts briefly mention the research, others echo key concepts like neurodegeneration and therapeutic targets, indicating moderate engagement.

ImpactModerate impact

The discussions convey that understanding these cellular processes could significantly influence future treatments, suggesting a notable impact.

Abstract in brief

  • The article discusses how abnormal tau proteins and defective autophagy and mitophagy (cellular processes that clean up damaged parts, especially mitochondria) are linked in the development of Alzheimer's disease (AD), potentially creating a harmful cycle that worsens neurodegeneration.
  • It highlights that both nonselective and selective autophagy, particularly mitophagy, are involved in AD pathology, with dysfunctional mitochondria playing a key role in tau-related diseases.
  • The review explores how neuroinflammation interacts with autophagy and mitophagy, and suggests potential new treatments targeting these processes, such as rapamycin, curcumin, and other compounds.]

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease https://t.co/Y5crKscl0a https://t.co/OMKxpdot56

Nov 2, 2022 · 21 likes · 3 shares · 41,523 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease: Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting… https://t.co/cs3QWA7gf7 #ageing #neuroscience

Oct 28, 2022 · 5 likes · 4 shares · 80,782 followers View post →
Orlando_uy
@Orlando_uy · X

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease https://t.co/by63mjBcKY

Dec 7, 2022 · 1 like · 1 share · 692 followers View post →
iBraiN Inserm Lab
@iBrain_Inserm · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Oct 29, 2022 · 4 shares · 1,723 followers View post →
Omar Hammouda
@HammoudaOm · X

RT @agingdoc1: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s…

Nov 3, 2022 · 3 shares · 804 followers View post →
Sebastián Morales Durán
@smorales_fcien · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Oct 28, 2022 · 4 shares · 490 followers View post →

All mentions

Orlando_uy
@Orlando_uy · X

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease https://t.co/by63mjBcKY

Dec 7, 2022 · 1 like · 1 share · 692 followers View post →
Lala
@CNSProteostasis · X

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer's disease https://t.co/nZAjmwc2vP https://t.co/qcUYMxDgTU

Nov 27, 2022 · 20 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @agingdoc1: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s…

Nov 3, 2022 · 3 shares · 210 followers View post →
N. Moncada
@ChiguiMedicina · X

RT @agingdoc1: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s…

Nov 3, 2022 · 3 shares · 273 followers View post →
Omar Hammouda
@HammoudaOm · X

RT @agingdoc1: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s…

Nov 3, 2022 · 3 shares · 804 followers View post →
Agingdoc
@agingdoc1 · X

The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease https://t.co/Y5crKscl0a https://t.co/OMKxpdot56

Nov 2, 2022 · 21 likes · 3 shares · 41,523 followers View post →
Neha Yadav
@neha_sunshine · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Nov 1, 2022 · 4 shares · 34 followers View post →
iBraiN Inserm Lab
@iBrain_Inserm · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Oct 29, 2022 · 4 shares · 1,723 followers View post →
Nonso Nduka
@NonsoNduka3 · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Oct 28, 2022 · 4 shares · 211 followers View post →
Sebastián Morales Durán
@smorales_fcien · X

RT @FrontNeurosci: New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implicatio…

Oct 28, 2022 · 4 shares · 490 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease: Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting… https://t.co/cs3QWA7gf7 #ageing #neuroscience

Oct 28, 2022 · 5 likes · 4 shares · 80,782 followers View post →