#OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up of patients who received coronary stenting #AHAJournals https://t.co/UY7s9MyjPe https://t.co/QgGczLjudn
Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study.
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Nov 2022 – Aug 2025Where it's discussed
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X / Twitter120 posts
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News6 articles
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Facebook3 posts
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YouTube2 videos
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AI synopsis
What people are saying
The discussions highlight key findings, such as the lower rates of cardiovascular events associated with clopidogrel compared to aspirin, which is reflected in phrases like 'clopidogrel safer and more effective' and 'why do we use aspirin rather than P2Y12 inhibitors for long-term prevention?' The choice of words such as 'better,' 'significant,' and 'reanalysis' showcases a tone of urgency and importance, contributing to the overall sentiment that the study's conclusions are vital for future treatment considerations.
Overall, a moderate level of agreement is reflected in the discussions, with many participants supporting or acknowledging the findings of the HOST-EXAM study.
There is a high level of curiosity surrounding the article, as many participants engage with the findings and express interest in the implications for treatment.
While many posts engage with the study's results, some responses are dismissive, suggesting varying depths of engagement on the topic.
The perceived impact of the study is significant, as participants recognize its importance for clinical practice in cardiology.
Abstract in brief
- The HOSTEXAM Extended Study compared long-term outcomes of clopidogrel versus aspirin in patients who underwent percutaneous coronary intervention with drug-eluting stents.
- A total of 5,438 patients who were free of clinical events after 12 months of dual antiplatelet therapy were assigned to either clopidogrel 75 mg or aspirin 100 mg daily, with the study focusing on a median follow-up of about 5.8 years.
- Results show that clopidogrel was associated with lower risks for major cardiovascular events and bleeding complications compared to aspirin, suggesting it may be a more effective option for long-term maintenance therapy.
Top posts
Most liked on X and BlueskyThe new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommendation for chronic CAD thx. Based on the HOST Exam trial https://t.co/HXXn9uxIlb and the CAPRIE trial https://t.co/hGGrZppFLv what is your practice? #esccongress
「抗血小板薬1剤残すならP2Y12i」は知らなかった
Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
poor metabolizer問題はありますが,長期でみるとやはりクロピドグレルは良い薬ですよねえ。 ■PCI後DAPT後,SAPTどっち残すか問題RCT(n=5438):Clop75 vs ASA100 で心血管イベント(12.8% vs 16.9%)も出血イベント(4.5% vs 6.1%)もClopが優越性。 追跡期間中央値は約6年! https://t.co/qh9qQQVz03
【文献メモ】(こっちですね!) Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study https://t.co/roxMLm77lW
All mentions
Clopidogrel vs. Aspirin: Insights from Recent Cardiology Studies
This week, John Mandrola MD discusses the Ticagrelor controversy and new RCTs showing clopidogrel may outperform aspirin in noncardiac surgery. The HOST-EXAM study highlights clopidogrel's effectiveness for long-term…
Clopidogrel versus Aspirin in Long-Term Cardiovascular Care
This video discusses listener feedback on antiplatelet therapy after PCI, focusing on the HOST-EXAM study that compared long-term outcomes of clopidogrel versus aspirin. Clopidogrel demonstrated lower risks of major…
https://t.co/DmVYdone6S
@drkeithsiau @drmineg @battyberd Sorry but I recall multiple studies saying that clopidogrel is associated with lower bleeding risk than aspirin? https://t.co/pXue3Isd53 https://t.co/seGQjJPV0v
RT @bunken_kensaku: 【文献メモ】(こっちですね!) Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Interventi…
RT @bunken_kensaku: 【文献メモ】(こっちですね!) Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Interventi…
【文献メモ】(こっちですね!) Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study https://t.co/roxMLm77lW
@DrRajeshG1 @drmjp93 @DrSanjay277 @Vighrane01 @drmohansai https://t.co/sFr8uis1Oz Actually plavix monotherapy is better, sir. Conclusively proven recently.
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
RT @CMichaelGibson: The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommend…
The new ESC guidelines give Aspirin mono therapy a Class 1 recommendation & thienopyridine therapy a class 2b recommendation for chronic CAD thx. Based on the HOST Exam trial https://t.co/HXXn9uxIlb and the CAPRIE trial https://t.co/hGGrZppFLv what is your practice? #esccongress
RT @Cardio_Pharm_JP: https://t.co/8oclj77pTN
https://t.co/8oclj77pTN
During a median follow-up of 5.8 years in those 6-18 months after PCI, clopidogrel had lower rates of both the secondary thrombotic and secondary bleeding endpoints compared to aspirin with combined NNT of 37. https://t.co/LwFnpbbRzO
SAPT: Aspirin or clopidogrel? HOST-EXAM trial (Lancet 21): Clopidogrel safer and more effective » Reanalysis at 6y w/ maintained benefit I haven't seen it into practice. Status quo? South-coreans only? If 2nd, not the only study but maybe best so far https://t.co/ykaOuQGzce
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @farukumayaku: 「抗血小板薬1剤残すならP2Y12i」は知らなかった
「抗血小板薬1剤残すならP2Y12i」は知らなかった
RT @EvidenceObasan: poor metabolizer問題はありますが,長期でみるとやはりクロピドグレルは良い薬ですよねえ。 ■PCI後DAPT後,SAPTどっち残すか問題RCT(n=5438):Clop75 vs ASA100 で心血管イベント(12.8%…
poor metabolizer問題はありますが,長期でみるとやはりクロピドグレルは良い薬ですよねえ。 ■PCI後DAPT後,SAPTどっち残すか問題RCT(n=5438):Clop75 vs ASA100 で心血管イベント(12.8% vs 16.9%)も出血イベント(4.5% vs 6.1%)もClopが優越性。 追跡期間中央値は約6年! https://t.co/qh9qQQVz03
RT @rincondesisifo: (Circulation) Seguridad y eficacia a largo plazo del ácido acetilsalicílico vs clopidogrel en monoterapia en pac que ha…
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @RevistaMFSamfyc: Aspirina frente a clopidogrel para terapia de mantenimiento a largo plazo tras intervención coronaria percutánea: estu…
Aspirina frente a clopidogrel para terapia de mantenimiento a largo plazo tras intervención coronaria percutánea: estudio HOST-EXAM extendido https://t.co/BIbgeFq1Bd PMID 36342475
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @ChaturvediNeuro: HOST-EXAM extension study in @CircAHA shows 26% decrease in major adverse events (thrombotic events, major bleed) 12…
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @ChaturvediNeuro: HOST-EXAM extension study in @CircAHA shows 26% decrease in major adverse events (thrombotic events, major bleed) 12…
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @ChaturvediNeuro: HOST-EXAM extension study in @CircAHA shows 26% decrease in major adverse events (thrombotic events, major bleed) 12…
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
HOST-EXAM extension study in @CircAHA shows 26% decrease in major adverse events (thrombotic events, major bleed) 12 mos after PCI with clopidogrel mono-rx vs. aspirin. Should stroke clinicians convert more pts to clop. mono-rx after a course of DAPT? https://t.co/OMIAQqQ0xR
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
RT @SABOURETCardio: Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy #PCI #SAPT https://t.co/XuQy6gLOls
Why do we used aspirin rather than p2y12 inhibitors for longterm secondary prevention after #PCI. 5438 patients randomized 1:1 after a yr of #DAPT clopidogrel vs asa. clopidogrel w/⬇️net outcomes. Is it time to switch? Read more
Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study | Circulation https://t.co/c6o446QW96
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
RT @CircAHA: #OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up…
#OriginalResearch: Clopidogrel monotherapy was superior to aspirin monotherapy (following 6-18 mo DAPT) in long term follow-up of patients who received coronary stenting #AHAJournals https://t.co/UY7s9MyjPe https://t.co/QgGczLjudn
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
RT @SABOURETCardio: Do you still use #Aspirin Instead of #Clopidogrel for Long-Term Maintenance Monotherapy After #PCI ? Just consider the…
Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study https://t.co/sbzOuSPx8n #Cardiotwitter
The HOST-EXAM clopidogrel and AAS at 5.8 years similar all cause of death.https://t.co/7qoWjJnHPW If prolonged DAPT isn't the cause of an excess of non-cardiac death in recent DES trials who was? It is hard to believe thats happening by chance, 9903 pts randomized in 4 trials
RT @pinacol: 【追跡調査: HOST-EXAM】PCI後のDAPTで臨床イベントがなかった患者へのクロピドグレル投与は、アスピリン投与と比較して、延長した追跡期間中の全原因死亡、非致死性心筋梗塞、脳卒中、急性冠症候群による再入院、BARCタイプ3以上の出血の複合転帰…
【追跡調査: HOST-EXAM】PCI後のDAPTで臨床イベントがなかった患者へのクロピドグレル投与は、アスピリン投与と比較して、延長した追跡期間中の全原因死亡、非致死性心筋梗塞、脳卒中、急性冠症候群による再入院、BARCタイプ3以上の出血の複合転帰リスクを減少させた。 #ペ読 https://t.co/I7vrGC1dzo
Clopidogrel monotherapy as compared with aspirin monotherapy was associated with lower rates of the composite net clinical outcome in patients without clinical events for 12±6 months after percutaneous coronary intervention with drug-eluting stents. https://t.co/ddKwhdEOXQ