BMC Biol November 2022 PMID 36344967

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes.

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko

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Mentions

62
Peak: 28 in Nov 2022
across 5 sources since Dec 2021

Extended reach

1,444,801
potential audience

Total likes

51

Video views

159

Mentions per month

Dec 2021 – Jul 2023

Where it's discussed

  • X / Twitter35 posts
  • News20 articles
  • Blogs3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Several discussions emphasize the significance of the genomic assembly, using expressions like 'supports Nile rat as a model for diabetes' and 'expands potential for studying metabolic diseases.' Words such as 'incredible,' 'supports,' and 'new insights' highlight a tone of enthusiasm about the scientific breakthrough and its broad implications for future research.

AgreementStrong agreement

Many discussions explicitly highlight the significance of the Nile rat genome as a valuable model for diabetes research, with phrases like 'supports Nile rat animal model' and 'incredible model system,' indicating strong consensus on its importance.

InterestHigh interest

The conversations demonstrate high curiosity, referencing detailed genomic techniques and potential implications for human health, such as exploring genetic bases of diabetes and novel research models.

EngagementHigh engagement

Multiple posts delve into technical aspects—mentioning genome assembly, gene annotations, and advanced sequencing methods—showing deep engagement with the research.

ImpactHigh impact

The overall tone suggests this publication is perceived as highly impactful, with many posts emphasizing its potential to advance understanding of diabetes and improve treatment models for humans.

Abstract in brief

  • The study presents a high-quality, 2.5 Gb chromosome-level genome assembly of the Nile rat, a valuable model for diabetes research due to its similarities to humans in certain biological traits and its tendency to develop diet-induced diabetes.
  • The researchers used advanced sequencing techniques to identify complex genomic features like segmental duplications and gene variations, highlighting unique genetic factors linked to diabetes and metabolic issues in the Nile rat.
  • This detailed genomic data enhances the understanding of the Nile rat's genetics, positioning it as a powerful model organism for studying diabetes and metabolic diseases with better relevance to humans.

Top posts

Most liked on X and Bluesky
Greg Larssen
@GregLarssen · X

$BNGO - Bionano The wonders of science work. A genetics study of the Nile rat, using Bionano's OGM, shows that the Nile rat, with its propensity to develop diet-induced diabetes, is a perfect model for discovering diabetes solutions for humans. https://t.co/xVa8aVSwup

Nov 13, 2022 · 15 likes · 3 shares · 874 followers View post →
Olivier Fedrigo
@ofedrigo · X

One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incredible model system for studying diabetes. https://t.co/sfaQ02tXvF @genomewarriors @bllapin @jackie_mcastle @erichjarvis

Nov 8, 2022 · 14 likes · 8 shares · 746 followers View post →
Phys.org
@physorg_com · X

#Genome sequencing supports Nile rat animal model for diabetes research @Morgridge_Inst https://t.co/xyBRLYGXX8 https://t.co/4ta6cVeUA8

Nov 9, 2022 · 5 likes · 3 shares · 1,024,284 followers View post →
BMC Biology
@BMCBiology · X

On #WorldDiabetesDay, new #openaccess #research from @ybukhman, Mark Chaisson, Ron Stewart, James Thomson and co. provides a #genome assembly of the Nile rat, and insights on genes associated with type 2 #diabetes and #metabolic dysfunction https://t.co/fj7xDfgz9F https://t.co/oQ2laIUw8c

Nov 14, 2022 · 3 likes · 3 shares · 9,012 followers View post →
BMC
@BioMedCentral · X

A study published in @BMCBiology reports a reference-quality genome assembly of the Nile rat, expanding its potential as a model organism for diabetes research. https://t.co/lztDqAwO4i

Nov 13, 2022 · 2 likes · 75,419 followers View post →
Liz Tseng
@Magdoll · X

4/ @PacBio genome of Nile rat finds fewer copies of amylase gene compared to house mouse. Implication for type 2 diabetes research. New model system? https://t.co/bRFeABd9p6

Apr 5, 2023 · 2 likes · 3,946 followers View post →

All mentions

Yury V Bukhman
@ybukhman · X

My short talk at the ISMB 2023: https://t.co/VgEQ52KlNN

Jul 25, 2023 · 1 like · 47 followers View post →
Liz Tseng
@Magdoll · X

4/ @PacBio genome of Nile rat finds fewer copies of amylase gene compared to house mouse. Implication for type 2 diabetes research. New model system? https://t.co/bRFeABd9p6

Apr 5, 2023 · 2 likes · 3,946 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @physorg_com: #Genome sequencing supports Nile rat animal model for diabetes research @Morgridge_Inst https://t.co/xyBRLYGXX8 https://t.…

Nov 16, 2022 · 3 shares · 1,790 followers View post →
La Semaine Vétérinaire
@semainevet · X

RT @GIRCOR:

Nov 15, 2022 · 2 shares · 4,125 followers View post →
Sabry Neuro Biology
@Sabri88Dz · X

RT @GIRCOR:

Nov 15, 2022 · 2 shares · 258 followers View post →
Gircor, recherche animale et alternatives
@GIRCOR · X

Nov 15, 2022 · 2 likes · 2 shares · 3,946 followers View post →
Kihara Laboratory
@kiharalab · X

RT @BMCBiology: On #WorldDiabetesDay, new #openaccess #research from @ybukhman, Mark Chaisson, Ron Stewart, James Thomson and co. provides…

Nov 14, 2022 · 3 shares · 2,359 followers View post →
Gracy
@Gracy_ldn · X

RT @BMCBiology: On #WorldDiabetesDay, new #openaccess #research from @ybukhman, Mark Chaisson, Ron Stewart, James Thomson and co. provides…

Nov 14, 2022 · 3 shares · 487 followers View post →
Genome Biology
@GenomeBiology · X

RT @BMCBiology: On #WorldDiabetesDay, new #openaccess #research from @ybukhman, Mark Chaisson, Ron Stewart, James Thomson and co. provides…

Nov 14, 2022 · 3 shares · 89,952 followers View post →
BMC Biology
@BMCBiology · X

On #WorldDiabetesDay, new #openaccess #research from @ybukhman, Mark Chaisson, Ron Stewart, James Thomson and co. provides a #genome assembly of the Nile rat, and insights on genes associated with type 2 #diabetes and #metabolic dysfunction https://t.co/fj7xDfgz9F https://t.co/oQ2laIUw8c

Nov 14, 2022 · 3 likes · 3 shares · 9,012 followers View post →
EsikoR
@E_sikoR · X

RT @GregLarssen: $BNGO - Bionano The wonders of science work. A genetics study of the Nile rat, using Bionano's OGM, shows that the Nile…

Nov 14, 2022 · 3 shares · 15 followers View post →
Abu Elijah
@noriega_khan · X

RT @GregLarssen: $BNGO - Bionano The wonders of science work. A genetics study of the Nile rat, using Bionano's OGM, shows that the Nile…

Nov 14, 2022 · 3 shares · 80 followers View post →
N3
@n3groove · X

RT @GregLarssen: $BNGO - Bionano The wonders of science work. A genetics study of the Nile rat, using Bionano's OGM, shows that the Nile…

Nov 14, 2022 · 3 shares · 652 followers View post →
Greg Larssen
@GregLarssen · X

$BNGO - Bionano The wonders of science work. A genetics study of the Nile rat, using Bionano's OGM, shows that the Nile rat, with its propensity to develop diet-induced diabetes, is a perfect model for discovering diabetes solutions for humans. https://t.co/xVa8aVSwup

Nov 13, 2022 · 15 likes · 3 shares · 874 followers View post →
BMC
@BioMedCentral · X

A study published in @BMCBiology reports a reference-quality genome assembly of the Nile rat, expanding its potential as a model organism for diabetes research. https://t.co/lztDqAwO4i

Nov 13, 2022 · 2 likes · 75,419 followers View post →
Yury V Bukhman
@ybukhman · X

https://t.co/7fILJSyUHU

Nov 11, 2022 · 48 followers View post →
BMC Biology
@BMCBiology · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 10, 2022 · 8 shares · 9,012 followers View post →
Manu Gupta
@mgupt108 · X

RT @physorg_com: #Genome sequencing supports Nile rat animal model for diabetes research @Morgridge_Inst https://t.co/xyBRLYGXX8 https://t.…

Nov 10, 2022 · 3 shares · 5,114 followers View post →
Phys.org
@physorg_com · X

#Genome sequencing supports Nile rat animal model for diabetes research @Morgridge_Inst https://t.co/xyBRLYGXX8 https://t.co/4ta6cVeUA8

Nov 9, 2022 · 5 likes · 3 shares · 1,024,284 followers View post →
Phys.org Biology
@physorg_biology · X

RT @physorg_com: #Genome sequencing supports Nile rat animal model for diabetes research @Morgridge_Inst https://t.co/xyBRLYGXX8 https://t.…

Nov 9, 2022 · 3 shares · 8,209 followers View post →
Giulio Formenti
@giulio_formenti · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 9, 2022 · 8 shares · 537 followers View post →
Genki Terashi
@GTerashi · X

RT @kiharalab: Paper on the Nile rat genome just published in BMC Biology. We provided Gene Ontology annotation in this project. https://t.…

Nov 8, 2022 · 1 share · 230 followers View post →
Arima Genomics
@ArimaGenomics · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 1,245 followers View post →
Milton Tan
@mtanichthys · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 5,091 followers View post →
Erich Jarvis
@erichjarvis · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 6,440 followers View post →
Kihara Laboratory
@kiharalab · X

Paper on the Nile rat genome just published in BMC Biology. We provided Gene Ontology annotation in this project. https://t.co/1J1zYUjuk1 https://t.co/JYj5eA5cxD

Nov 8, 2022 · 1 like · 1 share · 2,359 followers View post →
Vertebrate Genomes Project (VGP)
@genomeark · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 3,295 followers View post →
Kristina (Kay) Weber
@KayBFX · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 243 followers View post →
Adam Phillippy
@aphillippy · X

RT @ofedrigo: One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incr…

Nov 8, 2022 · 8 shares · 16,402 followers View post →
Olivier Fedrigo
@ofedrigo · X

One of the first trio assemblies we have done is now published. A nice collaboration with @ybukhman on the Nile Rat. An incredible model system for studying diabetes. https://t.co/sfaQ02tXvF @genomewarriors @bllapin @jackie_mcastle @erichjarvis

Nov 8, 2022 · 14 likes · 8 shares · 746 followers View post →
Edinburgh Watch
@EdinburghWatch · X

RT @jsantoyo: A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. #NileRatGenome…

Dec 11, 2021 · 1 share · 12,023 followers View post →
Javier Santoyo
@jsantoyo · X

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. #NileRatGenome #HaplotypeResolvedAssembly #VGP https://t.co/SJHuS4B1Nx

Dec 11, 2021 · 1 share · 6,197 followers View post →
bxv_genomics
@bxv_genomics · X

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes https://t.co/Du5H4gxxWm

Dec 10, 2021 · 780 followers View post →
bioRxiv
@biorxivpreprint · X

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes https://t.co/Xpe10lcm9S #bioRxiv

Dec 10, 2021 · 137,389 followers View post →
bioRxiv Genomics
@biorxiv_genomic · X

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes https://t.co/faMsPG9sIp #biorxiv_genomic

Dec 10, 2021 · 11,801 followers View post →