PLoS Med December 2022 PMID 36454733

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case-control analysis.

Margaret L Lind, Alexander J Robertson, Julio Silva, Frederick Warner, Andreas C Coppi, Nathan Price, Chelsea Duckwall, Peri Sosensky, Erendira C Di Giuseppe, Ryan Borg, Mariam O Fofana, Otavio T Ranzani, Natalie E Dean, Jason R Andrews, Julio Croda

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Mentions

112
Peak: 15 in Dec 2022
across 4 sources since Dec 2022

Extended reach

448,992
potential audience

Total likes

35

Video views

15

Mentions per month

Dec 2022 – Apr 2025

Where it's discussed

  • News89 articles
  • X / Twitter19 posts
  • Blogs3 articles
  • YouTube1 videos

AI synopsis

What people are saying

The group reflects awareness of the study's nuanced findings, with comments like 'small boosts' and 'additional protection,' highlighting how vaccine effectiveness varies based on prior infection status. The tone balances concern and curiosity, suggesting that these findings could influence future vaccination approaches.

AgreementModerate agreement

Most discussions acknowledge the study's findings, with comments noting that boosters offer limited additional protection for previously infected individuals.

InterestModerate interest

Posts show moderate curiosity, with some highlighting the nuances, such as differences between those with and without prior infections.

EngagementModerate engagement

Participants are engaging with specific data points and implications, referencing reinfection rates and vaccine efficacy.

ImpactModerate impact

The discussions suggest a recognition of the study's relevance to ongoing vaccination strategies and public health policies.

Top posts

Most liked on X and Bluesky
PLOS Medicine
@PLOSMedicine · X

Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection. https://t.co/gV6KkAf6HR #COVID19 #vaccination #omicron https://t.co/FH1SKt1rYY

Dec 1, 2022 · 23 likes · 5 shares · 57,958 followers View post →
Dr Dave Cartland BMedSc MBChB Ex-MRCGP
@CartlandDavid · X

COVID-19 vaccine boosters provided very small boosts for people who have recovered from COVID-19, according to study. https://t.co/vldxclZywi

Apr 14, 2025 · 6 likes · 2 shares · 307,626 followers View post →
Agingdoc
@agingdoc1 · X

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis https://t.co/8FRwclNx2S

Dec 2, 2022 · 5 likes · 2 shares · 41,794 followers View post →
BCNT
@BCNThomson · X

@macroliter BA.1 reinfection/BTI rates: -Prior infection, post 2-dose vax (≥150 d): 6.1% -Prior infection, post 3-dose vax (≥14 d): 5.7% -No prior infection, post 2-dose vax: 8.9% -No prior infection, post 3-dose vax: 5.5% https://t.co/1xqiqDTsk3 No post-infection pathology studied here.

Dec 20, 2022 · 1 like · 459 followers View post →
Otavio Ranzani
@otavio_ranzani · X

RT @PLOSMedicine: Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omi…

Dec 2, 2022 · 5 shares · 34,620 followers View post →
CanCOVID
@CanCovid · X

An article was published in @PLOSMedicine on the association between primary or booster #COVID19 vaccination and #Omicron lineage infection in people with prior SARS-CoV-2 infection. The article was written by Lind et al. Find it here: https://t.co/QXsRhyirr2. https://t.co/8w5NWBd1eq

Dec 9, 2022 · 2,721 followers View post →

All mentions

Lesley Johnson
@LesleyLelly88 · X

RT @CartlandDavid: COVID-19 vaccine boosters provided very small boosts for people who have recovered from COVID-19, according to study. ht…

Apr 14, 2025 · 2 shares · 748 followers View post →
Na'eem
@satoru32495 · X

RT @CartlandDavid: COVID-19 vaccine boosters provided very small boosts for people who have recovered from COVID-19, according to study. ht…

Apr 14, 2025 · 2 shares · 22 followers View post →
Dr Dave Cartland BMedSc MBChB Ex-MRCGP
@CartlandDavid · X

COVID-19 vaccine boosters provided very small boosts for people who have recovered from COVID-19, according to study. https://t.co/vldxclZywi

Apr 14, 2025 · 6 likes · 2 shares · 307,626 followers View post →
@KenVOttawa
@Kenvinottawa · X

@E_RA_SUR @ctvottawa More on effectiveness moron https://t.co/S7qo1imZN7

Feb 12, 2023 · 778 followers View post →
BCNT
@BCNThomson · X

@macroliter BA.1 reinfection/BTI rates: -Prior infection, post 2-dose vax (≥150 d): 6.1% -Prior infection, post 3-dose vax (≥14 d): 5.7% -No prior infection, post 2-dose vax: 8.9% -No prior infection, post 3-dose vax: 5.5% https://t.co/1xqiqDTsk3 No post-infection pathology studied here.

Dec 20, 2022 · 1 like · 459 followers View post →
CanCOVID
@CanCovid · X

An article was published in @PLOSMedicine on the association between primary or booster #COVID19 vaccination and #Omicron lineage infection in people with prior SARS-CoV-2 infection. The article was written by Lind et al. Find it here: https://t.co/QXsRhyirr2. https://t.co/8w5NWBd1eq

Dec 9, 2022 · 2,721 followers View post →
juz
@juz28710242 · X

RT @JerryTess: "Bien que la vax de rappel ait été associée à une protection supplémentaire contre l'infection par Omicron chez les personne…

Dec 8, 2022 · 2 shares · 107 followers View post →
Bernie Simon
@Jinzang · X

While booster vaccination was associated with additional protection against Omicron BA.1 infection in people without a prior infection, it was not found to be associated with additional protection among people with a prior infection. https://t.co/OZhVZ6SJDI

Dec 7, 2022 · 454 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @agingdoc1: Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people wit…

Dec 2, 2022 · 2 shares · 107 followers View post →
Margaret (Maggie) Lind
@MaggieLind2 · X

RT @PLOSMedicine: Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omi…

Dec 2, 2022 · 5 shares · 148 followers View post →
valeria campos
@valeria62893304 · X

RT @PLOSMedicine: Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omi…

Dec 2, 2022 · 5 shares · 282 followers View post →
Otavio Ranzani
@otavio_ranzani · X

RT @PLOSMedicine: Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omi…

Dec 2, 2022 · 5 shares · 34,620 followers View post →
Jerry Tessap
@JerryTess · X

RT @JerryTess: "Bien que la vax de rappel ait été associée à une protection supplémentaire contre l'infection par Omicron chez les personne…

Dec 2, 2022 · 2 shares · 238 followers View post →
Derfel-ap-arthur
@ap_derfel · X

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis | PLOS Medicine https://t.co/x6nyzi1Us7

Dec 2, 2022 · 440 followers View post →
Agingdoc
@agingdoc1 · X

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case–control analysis https://t.co/8FRwclNx2S

Dec 2, 2022 · 5 likes · 2 shares · 41,794 followers View post →
Cardio-Targets
@CardioTargets · X

Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case-control analysis https://t.co/mRf2zubrTF

Dec 1, 2022 · 153 followers View post →
Jerry Tessap
@JerryTess · X

"Bien que la vax de rappel ait été associée à une protection supplémentaire contre l'infection par Omicron chez les personnes SANS infection antérieure, elle n'a pas été associée à une protection supplémentaire chez celles AYANT une infection antérieure" https://t.co/PIzudoXJG0

Dec 1, 2022 · 2 shares · 238 followers View post →
Association for Computational Health
@AssocCompHealth · X

RT @PLOSMedicine: Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omi…

Dec 1, 2022 · 5 shares · 2 followers View post →
PLOS Medicine
@PLOSMedicine · X

Margaret L. Lind and colleagues, investigate the association between primary or booster COVID-19 mRNA vaccination and omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection. https://t.co/gV6KkAf6HR #COVID19 #vaccination #omicron https://t.co/FH1SKt1rYY

Dec 1, 2022 · 23 likes · 5 shares · 57,958 followers View post →