June 2022 PMID 36475294

Changes in physical activity during a one-year weight loss trial with liraglutide vs placebo in participants with knee osteoarthritis: Secondary analyses of a randomised controlled trial.

Cecilie Bartholdy, Anders Overgaard, Henrik Gudbergsen, Henning Bliddal, Lars Erik Kristensen, Marius Henriksen

Mentions

8
Peak: 3 in Mar 2022
across 2 sources since Mar 2022

Extended reach

6,828
potential audience

Total likes

32

Video views

1,097

Mentions per month

Mar 2022 – Jan 2025

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions highlight that despite positive outcomes on weight and physical function, physical activity levels did not significantly increase, with comments emphasizing the need for targeted physical activity interventions. The tone is measured, recognizing both the benefits and limitations of the medication, which contributes to the moderate scores across the dimensions.

AgreementModerate agreement

Most posts acknowledge the findings that liraglutide improves weight and function but does not increase physical activity, showing general agreement.

InterestModerate interest

Discussions show moderate curiosity about the implications for treatment and behavior change, but not highly passionate.

EngagementModerate engagement

Comments reflect some reflection on the limitations and future needs, indicating moderate engagement.

ImpactNeutral impact

While the findings are relevant to obesity and osteoarthritis treatment, the overall influence on practice seems moderate at this stage.

Abstract in brief

  • The study aimed to evaluate changes in physical activity after one year of weight loss using liraglutide in overweight patients with knee osteoarthritis.
  • Participants were randomly assigned to receive either liraglutide or a placebo, and their physical activity was measured using accelerometers.
  • Results showed no significant change in daily physical activity for either group, even though the liraglutide group lost more weight and reported better physical functioning compared to the placebo group.

Top posts

Most liked on X and Bluesky
Osteoarthritis and Cartilage Journals
@OACJournal · X

Mar 19, 2022 · 4 likes · 2 shares · 4,325 followers View post →
Centre for Musculoskeletal Outcomes Research
@CMOR_Otago · X

Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not increase physical activity over one year, compared with placebo. Neither group acheived recommended PA levels. Targeted PA rx is needed! https://t.co/67pqdpThSD

Apr 10, 2022 · 1 like · 2 shares · 526 followers View post →
Simon Cummings
@ExerciseAuthor · X

RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…

Apr 11, 2022 · 2 shares · 616 followers View post →
Osteoarthritis Aotearoa NZ
@OA_AoNZ · X

RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…

Apr 10, 2022 · 2 shares · 157 followers View post →
Erin Deuss
@ARIVARASANE · X

RT @OACJournal:

Mar 20, 2022 · 2 shares · 62 followers View post →
William Lau
@RockLiu12 · X

RT @OACJournal:

Mar 19, 2022 · 2 shares · 22 followers View post →

All mentions

Simon Cummings
@ExerciseAuthor · X

RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…

Apr 11, 2022 · 2 shares · 616 followers View post →
Osteoarthritis Aotearoa NZ
@OA_AoNZ · X

RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…

Apr 10, 2022 · 2 shares · 157 followers View post →
Centre for Musculoskeletal Outcomes Research
@CMOR_Otago · X

Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not increase physical activity over one year, compared with placebo. Neither group acheived recommended PA levels. Targeted PA rx is needed! https://t.co/67pqdpThSD

Apr 10, 2022 · 1 like · 2 shares · 526 followers View post →
Erin Deuss
@ARIVARASANE · X

RT @OACJournal:

Mar 20, 2022 · 2 shares · 62 followers View post →
William Lau
@RockLiu12 · X

RT @OACJournal:

Mar 19, 2022 · 2 shares · 22 followers View post →
Osteoarthritis and Cartilage Journals
@OACJournal · X

Mar 19, 2022 · 4 likes · 2 shares · 4,325 followers View post →