Changes in physical activity during a one-year weight loss trial with liraglutide vs placebo in participants with knee osteoarthritis: Secondary analyses of a randomised controlled trial.
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Mar 2022 – Jan 2025Where it's discussed
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X / Twitter6 posts
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YouTube2 videos
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What people are saying
The discussions highlight that despite positive outcomes on weight and physical function, physical activity levels did not significantly increase, with comments emphasizing the need for targeted physical activity interventions. The tone is measured, recognizing both the benefits and limitations of the medication, which contributes to the moderate scores across the dimensions.
Most posts acknowledge the findings that liraglutide improves weight and function but does not increase physical activity, showing general agreement.
Discussions show moderate curiosity about the implications for treatment and behavior change, but not highly passionate.
Comments reflect some reflection on the limitations and future needs, indicating moderate engagement.
While the findings are relevant to obesity and osteoarthritis treatment, the overall influence on practice seems moderate at this stage.
Abstract in brief
- The study aimed to evaluate changes in physical activity after one year of weight loss using liraglutide in overweight patients with knee osteoarthritis.
- Participants were randomly assigned to receive either liraglutide or a placebo, and their physical activity was measured using accelerometers.
- Results showed no significant change in daily physical activity for either group, even though the liraglutide group lost more weight and reported better physical functioning compared to the placebo group.
Top posts
Most liked on X and BlueskyDespite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not increase physical activity over one year, compared with placebo. Neither group acheived recommended PA levels. Targeted PA rx is needed! https://t.co/67pqdpThSD
RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…
RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…
RT @OACJournal:
RT @OACJournal:
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RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…
RT @CMOR_Otago: Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not incr…
Despite better outcomes on body weight and function, people with knee #osteoarthritis treated with liraglutide did not increase physical activity over one year, compared with placebo. Neither group acheived recommended PA levels. Targeted PA rx is needed! https://t.co/67pqdpThSD
RT @OACJournal:
RT @OACJournal: