Am J Psychiatry January 2023 PMID 36475374

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial.

Stefanie Russman Block, Luke J Norman, Xiaoxi Zhang, Kristin A Mannella, Huan Yang, Mike Angstadt, James L Abelson, Joseph A Himle, Stephan F Taylor, Kate D Fitzgerald

Mentions

17
Peak: 8 in Jan 2023
across 4 sources since Dec 2022

Extended reach

60,060
potential audience

Total likes

15

Video views

126

Mentions per month

Dec 2022 – Apr 2023

Where it's discussed

  • X / Twitter12 posts
  • YouTube2 videos
  • Reddit2 posts
  • Blogs1 articles

AI synopsis

What people are saying

The overall tone shows that these discussions appreciate the study's contribution to understanding OCD treatment responses, especially mentioning brain connectivity as a predictor, with phrases like 'promising approach' and 'potential game-changer.' The tone varies from cautious optimism to curiosity, reflecting a moderate level of engagement and recognition of impact based on example mentions of how pre-treatment scans could guide individualized therapy.

AgreementModerate agreement

Most discussions recognize the significance of brain connectivity patterns in predicting therapy response, showing general support for the study's findings.

InterestModerate interest

Posts express moderate interest, highlighting the potential of resting-state brain scans to inform treatment, but without deep technical engagement.

EngagementModerate engagement

Many discussions reference the study's methodology and implications, indicating some level of active engagement beyond surface reactions.

ImpactModerate impact

The discussions suggest this research could influence future clinical approaches and understanding of OCD treatments, pointing to a moderate perceived impact.

Abstract in brief

  • This study examined how different brain connectivity patterns in adolescents and adults with OCD relate to their response to two types of therapy—exposure and response prevention (ERP) and stress management therapy (SMT)—by using resting-state fMRI scans.
  • The findings showed that ERP was generally more effective at reducing OCD symptoms and was linked to decreased connectivity between the vmPFC and subcortical regions like the caudate and thalamus, especially in unmedicated patients; greater symptom improvements were associated with enhanced connectivity in brain regions involved in cognitive control.
  • The study also highlighted developmental differences, with adolescents benefiting more from increased connectivity between frontoparietal regions and the nucleus accumbens, whereas adults showed improvements associated with connectivity in frontoparietal regions alone, implying that treatment response may depend on age-specific brain circuitry patterns.]

Top posts

Most liked on X and Bluesky
Journals of The American Psychiatric Association
@APAPubJournals · X

Our January 2023 AJP Audio #podcast episode features a discussion with Dr. Stefanie Russman Block about a trial looking at whether connectivity patterns in the brain can be used to predict #psychotherapy treatment response in patients with #OCD. https://t.co/QPRhkN6G3d https://t.co/36IDBDz7VB

Jan 13, 2023 · 6 likes · 2 shares · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

A study of pretreatment brain scans of adolescents and adults with #OCD found that the way certain brain regions talk to one another at rest predicted how well patients would respond to 3 months of #psychotherapy. https://t.co/M9rV0wX8sk https://t.co/xlYOeVgqIv

Dec 8, 2022 · 4 likes · 2 shares · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

AJP Deputy Editor Danny Pine highlights two articles from the January 2023 issue. https://t.co/MB4cgLGfYb

Jan 30, 2023 · 2 likes · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

4. “Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial,” by Stefanie Russman Block, Ph.D., et al. 4/4 https://t.co/7yhhaaQkli

Jan 30, 2023 · 1 like · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial https://t.co/7yhhaaQkli

Jan 30, 2023 · 1 like · 11,606 followers View post →
Luke Norman
@Luke_J_Norman · X

RT @APAPubJournals: A study of pretreatment brain scans of adolescents and adults with #OCD found that the way certain brain regions talk t…

Dec 8, 2022 · 2 shares · 758 followers View post →

All mentions

Sappy4005
@Sappy4005 · X

@fredlau1101 美国精神病学杂志只能通过库来下。不过你可以试试你买的库里有没有这篇:Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial

Apr 6, 2023 · 227 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

4. “Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial,” by Stefanie Russman Block, Ph.D., et al. 4/4 https://t.co/7yhhaaQkli

Jan 30, 2023 · 1 like · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial https://t.co/7yhhaaQkli

Jan 30, 2023 · 1 like · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

AJP Deputy Editor Danny Pine highlights two articles from the January 2023 issue. https://t.co/MB4cgLGfYb

Jan 30, 2023 · 2 likes · 11,606 followers View post →
Marco A. Sanchez R.
@marcorenteria61 · X

RT @APAPubJournals: Our January 2023 AJP Audio #podcast episode features a discussion with Dr. Stefanie Russman Block about a trial looking…

Jan 13, 2023 · 2 shares · 507 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Our January 2023 AJP Audio #podcast episode features a discussion with Dr. Stefanie Russman Block about a trial looking at whether connectivity patterns in the brain can be used to predict #psychotherapy treatment response in patients with #OCD. https://t.co/QPRhkN6G3d https://t.co/36IDBDz7VB

Jan 13, 2023 · 6 likes · 2 shares · 11,606 followers View post →
MoonShineMcGee
@MisterWheeze · X

January 2023: Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial #americanJournalOfPsychiatryAudio https://t.co/PwbasGqcvg via @PodcastAddict

Jan 3, 2023 · 151 followers View post →
Luke Norman
@Luke_J_Norman · X

RT @APAPubJournals: A study of pretreatment brain scans of adolescents and adults with #OCD found that the way certain brain regions talk t…

Dec 8, 2022 · 2 shares · 758 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

A study of pretreatment brain scans of adolescents and adults with #OCD found that the way certain brain regions talk to one another at rest predicted how well patients would respond to 3 months of #psychotherapy. https://t.co/M9rV0wX8sk https://t.co/xlYOeVgqIv

Dec 8, 2022 · 4 likes · 2 shares · 11,606 followers View post →
TC_papers
@TC_papers · X

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial https://t.co/Mek4ZTb6O3

Dec 7, 2022 · 212 followers View post →
Psychiatry.dev
@Psychiatrydev · X

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial – https://t.co/IwGiGXgP9A

Dec 7, 2022 · 2 followers View post →
Psychiatry.dev
@Psychiatrydev · X

Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial – https://t.co/Ty4tZDX32t

Dec 7, 2022 · 2 followers View post →
Linear mixed effects models in fMRI analysis : r/neuroimaging
Reddit

Hope it will be useful to anyone who is interested :) Sure, here it is: https://doi.org/10.1176/appi.ajp.21111173. If you cannot access it ...

Feb 20, 2023 View →
Is the brain capable of guiding treatment for OCD?
Blogs

[3] https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.21111173 [4] https://www.columbiapsychiatry.org/research/research-areas/child-and ...

Feb 13, 2023 View →
[Article] Resting-State Connectivity and Response to Psychotherapy ...
Reddit

AJP Published Online:**7 Dec 2022 DOI: https://doi.org/10.1176/appi.ajp.21111173 URL: https://doi.org/10.1176/appi.ajp.21111173.

Dec 8, 2022 View →