Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations: https://t.co/BELaY8RnYE
Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Dec 2022 – Aug 2023Where it's discussed
-
X / Twitter8 posts
-
News4 articles
-
YouTube2 videos
-
Blogs2 articles
AI synopsis
What people are saying
The discussions reflect a positive reception, with mentions like 'Condensates form small-world networks' and statements such as 'these structures influence biochemical functions,' demonstrating appreciation and curiosity. The tone suggests respect for the research's significance but stops short of extensive debate or critical analysis.
All discussions recognize and affirm the main findings of the publication, indicating strong overall support.
Participants show moderate curiosity, often referencing the significance of the small-world structures and biological relevance.
Comments include some elaboration on the mechanisms and implications, but lack deep technical critique or alternative viewpoints.
The discussions suggest that the findings are considered meaningful within the scientific community, though not universally deemed revolutionary.
Abstract in brief
- Condensates formed by prion-like low complexity domains (PLCDs) have small-world network structures with interfaces shaped by expanded conformations, which influence their biochemical functions.
- The formation of these condensates involves coupled phase transitions, such as phase separation and percolation, driven by multivalent associative interactions mediated by cohesive motifs called stickers and the spacers that regulate their cooperativity.
- Simulations show that within condensates, PLCD molecules are organized into reversible networks with small-world topology, displaying spatial inhomogeneity, especially at interfaces, which primes these structures for biological activity.
Top posts
Most liked on X and BlueskyNat. Commun.: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations https://t.co/noF2LY9wcO
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
All mentions
Small-World Network Structures in Prion-Like Protein Condensates
Condensates formed by prion-like low-complexity domains exhibit small-world network structures. These structures, with interfaces shaped by expanded conformations, influence their biological functions and are driven by…
Small-World Network Structures in Prion-Like Domain Condensates
Condensates formed by prion-like low-complexity domains exhibit small-world network structures with interfaces shaped by expanded conformations, influencing their biochemical functions and organization, driven by…
Nat. Commun.: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations https://t.co/noF2LY9wcO
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
RT @ShorterLab: Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expan…
Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations: https://t.co/BELaY8RnYE