February 2023 PMID 36642814

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks.

Nikhil Dave, Jessica M Judd, Annika Decker, Wendy Winslow, Patrick Sarette, Oscar Villarreal Espinosa, Savannah Tallino, Samantha K Bartholomew, Alina Bilal, Jessica Sandler, Ian McDonough, Joanna K Winstone, Erik A Blackwood, Christopher Glembotski, Timothy Karr

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Mentions

88
Peak: 30 in Jan 2023
across 5 sources since Aug 2022

Extended reach

942,869
potential audience

Total likes

322

Video views

18,219

Mentions per month

Aug 2022 – Apr 2025

Where it's discussed

  • X / Twitter51 posts
  • News27 articles
  • Reddit4 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect widespread agreement about the critical role of dietary choline in preventing systemic organ damage and cognitive decline, with posts describing the study as 'necessary' and referencing its groundbreaking nature, which underscores the high impact of this research. Words like 'benefits,' 'necessary,' and references to high-visibility articles indicate both interest and recognition of the importance of these findings.

AgreementStrong agreement

Most discussions support the importance of dietary choline, emphasizing its role in preventing organ damage and Alzheimer's features, indicating strong consensus.

InterestModerate interest

Posts show moderate interest by highlighting new research and its potential implications, yet some focus mainly on sharing the article rather than in-depth dialogue.

EngagementModerate engagement

Participants reference multiple studies and comment on research significance, but there’s limited critical discussion or alternative viewpoints, suggesting moderate engagement.

ImpactHigh impact

The numerous references to scientific findings and mention of the research as a top-viewed publication suggest these discussions could influence recent health and dietary perspectives.

Abstract in brief

  • Dietary choline is essential for preventing widespread organ damage and reducing Alzheimer's disease markers, with most Americans failing to meet recommended intake levels.
  • A study on mice showed that a choline-deficient diet led to physical, metabolic, and brain-related issues, especially in mice genetically predisposed to Alzheimer's.
  • The research suggests that maintaining adequate dietary choline could be crucial for protecting organs and reducing Alzheimer's symptoms through its role in brain function, metabolism, and protein networks.]

Top posts

Most liked on X and Bluesky
Neuroscience News
@NeuroscienceNew · X

“Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks” by Ramon Velazquez et al. Aging Cell https://t.co/bLdRu5dUa1

Jan 17, 2023 · 44 likes · 8 shares · 505,838 followers View post →
Agingdoc
@agingdoc1 · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 32 likes · 9 shares · 41,781 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/zoE5vcsmVZ

Jul 25, 2023 · 16 likes · 2 shares · 9,725 followers View post →
Margit Slimáková
@MSlimakova · X

Obhajoba konzumace masa / tedy skutečného jídla v podcastu u vegetariánů - jak jsme to zvládli? Přesvěčte se a dejte vědět, jak vnímáte vy. https://t.co/dpKmc3Tj3h https://t.co/v4N2lVoLbW

Jul 25, 2024 · 7 likes · 5,004 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/zoE5vcrP6r

Oct 28, 2023 · 6 likes · 9,725 followers View post →
Tyrone Williams
@ImmuneHack · X

~90% of Americans consume less than the recommended amount of choline. In a mouse model, a deficiency in choline results in inflammation, metabolic & cognitive dysfunction including dementia. https://t.co/35Muddh0BT

Jan 18, 2023 · 3 likes · 9,127 followers View post →

All mentions

Exploring Soy Nutrition with Margit Slimáková

In this episode, we discuss nutrition with Margit Slimáková, a nutrition specialist and advocate for real food. Topics include the benefits and controversies surrounding soy, dietary preferences, and the impacts of…

Hostina · Jul 23, 2024 17,769 views
Oscar Villarreal-Espinosa
@OscarIVE97 · X

Congratulations to my team - Velazquez lab at the Neurodegenerative Disease Research Center at @ASU @ASUBiodesign Our article on Choline Supplementation received enough views to be a Top Viewed Article. Read it here https://t.co/ur0ZSYmIg8 #TopViewedArticle @wileyinresearch

Apr 16, 2025 · 2 likes · 12 followers View post →
Margit Slimáková
@MSlimakova · X

Obhajoba konzumace masa / tedy skutečného jídla v podcastu u vegetariánů - jak jsme to zvládli? Přesvěčte se a dejte vědět, jak vnímáte vy. https://t.co/dpKmc3Tj3h https://t.co/v4N2lVoLbW

Jul 25, 2024 · 7 likes · 5,004 followers View post →
Sarah Rice
@sarah4info · X

2/ Dietary choline intake is necessary to prevent systems‐wide organ pathology & reduce Alzheimer's disease hallmarks preclinical study 'choline deficiency ...led to motor impairments, wt gain, impaired glucose metabolism, cardiac pathology, & liver dx https://t.co/NoE8uZvpGn

Jun 3, 2024 · 2 likes · 911 followers View post →
rp
@raypeater · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's diseas.. https://t.co/HJ2OKaUVMm #raypeat

Jan 10, 2024 · 1 like · 471 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/zoE5vcrP6r

Oct 28, 2023 · 6 likes · 9,725 followers View post →
Daniel Grimaldes MD
@DrGrimaldesJ · X

❌ Choline deficiency in the diet produces

Sep 27, 2023 · 1,015 followers View post →
Magnesium Girl - yin solutions for a yang world
@LocalRachel · X

RT @mike_lustgarten: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks…

Jul 29, 2023 · 2 shares · 8,873 followers View post →
Tomaso Antonacci
@TomasoAntonacci · X

RT @mike_lustgarten: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks…

Jul 25, 2023 · 2 shares · 2,386 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/zoE5vcsmVZ

Jul 25, 2023 · 16 likes · 2 shares · 9,725 followers View post →
Steven M. Belknap, MD PGY43
@StevenMBelknap · X

@rainerickson @ScepticalDoctor The point is “that dietary choline intake is necessary to prevent systems‐wide organ pathology…” This is not “majoring in minor things!” As to your claim: What single research result best supports the claim that a 100% plant-based diet provides adequate nutrition for health?

Jun 23, 2023 · 2,203 followers View post →
Rene Sugar
@renesugar · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/Ha5F8QkPCI

Jun 12, 2023 · 1 like · 3,969 followers View post →
Choline For Life
@CholineForLife · X

RT @fxvitality: Benefits of choline #choline #brainhealth https://t.co/2gVHB9MaHq

Mar 24, 2023 · 1 share · 812 followers View post →
Melanie Rathbun , R.H.N., FNC, FMCHC
@fxvitality · X

Benefits of choline #choline #brainhealth https://t.co/2gVHB9MaHq

Mar 23, 2023 · 1 like · 1 share · 336 followers View post →
Advanced Biology
@Adv_Biology · X

Checkout this great Research Article from Aging Cell, entitled 'Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks' Click below for more! #Wiley #AcademicChatter #AcademicTwitter #Aging https://t.co/XRdZGX4NU6

Feb 16, 2023 · 635 followers View post →
John Tye
@johntyehealth · X

‘There is an urgent need to identify modifiable environmental risk factors that reduce the incidence of Alzheimer's disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions.’ Nikhil Dave and Jes…https://t.co/Y0tlbYWOnX https://t.co/rnRFGwO3AX

Feb 14, 2023 · 10 followers View post →
John Tye
@johntyehealth · X

‘There is an urgent need to identify modifiable environmental risk factors that reduce the incidence of Alzheimer's disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions.’ Nikhil Dave and Jes…https://t.co/d26fBsLGfe https://t.co/We4iGVNmzr

Feb 14, 2023 · 10 followers View post →
John Tye
@johntyehealth · X

‘There is an urgent need to identify modifiable environmental risk factors that reduce the incidence of Alzheimer's disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions.’ Nikhil Dave and Je…https://t.co/NNfkUFMSSA https://t.co/cslF1DkBhH

Feb 14, 2023 · 10 followers View post →
John Tye
@johntyehealth · X

‘There is an urgent need to identify modifiable environmental risk factors that reduce the incidence of Alzheimer's disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions.’ Nikhil Dave and Je…https://t.co/8LIPoRp6Gu https://t.co/YVGLFAdzAn

Feb 14, 2023 · 10 followers View post →
John Tye
@johntyehealth · X

'Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks.' https://t.co/ywiEJ5KBtd

Feb 14, 2023 · 10 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

Study explores effects of dietary choline deficiency on neurologic and system-wide health https://t.co/vZsF7B4zn6 https://t.co/cpUHeOeyT5 https://t.co/3anXidoZox

Jan 28, 2023 · 93 followers View post →
Dr Sam Pappas
@DrSamPappas · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 20, 2023 · 8 shares · 2,092 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/ic9g5Q6ZEF https://t.co/UdU8JdTXCy

Jan 19, 2023 · 1 like · 24,147 followers View post →
Ariakas Enoreth
@Aenoreth · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/bCYbuVtdNJ

Jan 18, 2023 · 1,004 followers View post →
Brian Dean
@bdean_ · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 18, 2023 · 9 shares · 564 followers View post →
Let's Prolong Life
@hunt4longevity · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 18, 2023 · 9 shares · 8 followers View post →
UpToPhate
@UpToPhate · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/WMbggKPxCz

Jan 18, 2023 · 3 likes · 193 followers View post →
@thevelvetmeow.bsky.social
@thevelvetmeow · X

RT @Nutradvance: "Our data highlight that dietary choline intake is necessary to prevent systems-wide organ pathology and reduce hallmark A…

Jan 18, 2023 · 1 share · 782 followers View post →
Michael Joseph
@Nutradvance · X

"Our data highlight that dietary choline intake is necessary to prevent systems-wide organ pathology and reduce hallmark AD pathologies." https://t.co/lGPp5LjTG2 (in mice)

Jan 18, 2023 · 2 likes · 1 share · 11,780 followers View post →
José Luis Lugo
@JosLuisLugo17 · X

https://t.co/lrsob3TyY9

Jan 18, 2023 · 319 followers View post →
Reddit Journal of Science
@rsciencejournal · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks (Jan 2023) https://t.co/AclS3fEDwz #science #health #dietary #choline #intake #pathology

Jan 18, 2023 · 331 followers View post →
Tyrone Williams
@ImmuneHack · X

~90% of Americans consume less than the recommended amount of choline. In a mouse model, a deficiency in choline results in inflammation, metabolic & cognitive dysfunction including dementia. https://t.co/35Muddh0BT

Jan 18, 2023 · 3 likes · 9,127 followers View post →
Deric Cadora
@HighDefHealth · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 18, 2023 · 8 shares · 862 followers View post →
SabineRing
@ring_sabine · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 18, 2023 · 9 shares · 51 followers View post →
Rodrigue Brossaud PhD
@RodrigueB_PhD · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 18, 2023 · 9 shares · 168 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 9 shares · 77 followers View post →
CopperKettle
@Artyom_Yekat · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 17, 2023 · 8 shares · 384 followers View post →
Stephanie Holbrook
@sholbk · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 17, 2023 · 8 shares · 1,421 followers View post →
Amy Berger
@TuitNutrition · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 17, 2023 · 8 shares · 67,475 followers View post →
Ulfhedin
@karmapredator · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 17, 2023 · 8 shares · 44 followers View post →
sun_rug_S
@mizmizu97 · X

RT @NeuroscienceNew: “Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks”…

Jan 17, 2023 · 8 shares · 390 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer’s disease hallmarks” by Ramon Velazquez et al. Aging Cell https://t.co/bLdRu5dUa1

Jan 17, 2023 · 44 likes · 8 shares · 505,838 followers View post →
localhostscience
@localhostsci · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks (Jan 2023)

Jan 17, 2023 · 34 followers View post →
luis hernan graffe
@hernangraffe · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 9 shares · 3,155 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/CTF0IKvCEr

Jan 17, 2023 · 3,155 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 9 shares · 107 followers View post →
james Bond
@jamesBo74099976 · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 9 shares · 1,462 followers View post →
Syed Shaaban
@ShaabanSyed · X

RT @agingdoc1: Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 9 shares · 161 followers View post →
Agingdoc
@agingdoc1 · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

Jan 17, 2023 · 32 likes · 9 shares · 41,781 followers View post →
Dr Andrew Mitchell
@mitcharj · X

Dietary choline intake is necessary to prevent systems‐wide organ pathology and reduce Alzheimer's disease hallmarks https://t.co/NEDBamuTXo #ageing #choline via @AgingCell

Jan 17, 2023 · 3,757 followers View post →
bioRxiv
@biorxivpreprint · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimers disease hallmarks https://t.co/qYA343pJ2z #bioRxiv

Aug 15, 2022 · 2 likes · 137,379 followers View post →
bioRxiv Neuroscience
@biorxiv_neursci · X

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimers disease hallmarks https://t.co/l3zJVbF0Qy #biorxiv_neursci

Aug 15, 2022 · 60,054 followers View post →