January 2023 PMID 36678257

Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis.

Maria Bonvicini, Silvia Travaglini, Diana Lelli, Raffaele Antonelli Incalzi, Claudio Pedone

Mentions

60
Peak: 10 in Nov 2025
across 4 sources since Jan 2023

Extended reach

52,443
potential audience

Total likes

124

Video views

1,788

Mentions per month

Jan 2023 – Dec 2025

Where it's discussed

  • TikTok50 posts
  • X / Twitter6 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

This collection of discussions highlights a generally positive attitude toward citicoline as a cognitive support supplement, with some users expressing intent to try it based on research findings. The tone varies from supportive to cautiously optimistic, with references to scientific reviews and mentions of the need for more rigorous research, demonstrating a moderate level of engagement and influence in shaping opinions.

AgreementModerate agreement

Most of the discussions express support or positive impressions of citicoline, especially noting its potential cognitive benefits. However, some acknowledge the current evidence's limitations, indicating cautious optimism.

InterestHigh interest

There is high interest demonstrated by explicit mentions of trying citicoline for memory issues and interest in its role in preventing dementia, reflecting personal relevance and curiosity.

EngagementModerate engagement

Posts delve into specifics, such as referencing scientific studies and discussing the quality of research, indicating moderate engagement with the topic’s nuances.

ImpactNeutral impact

While the discussions show enthusiasm and curiosity, they mainly reflect individual opinions rather than widespread or actionable influence, resulting in a neutral impact score.

Abstract in brief

  • The systematic review and meta-analysis investigated whether citicoline can help prevent or slow down dementia by improving cognitive functions, especially in patients with mild cognitive impairment, Alzheimer’s disease, or post-stroke dementia.
  • The findings suggest that citicoline has a positive effect on cognitive performance, with pooled data showing improvements, but the overall quality of the studies was poor, indicating a need for more rigorous research.
  • While current evidence points to potential benefits of citicoline for cognition, the risk of bias and low-quality data mean its effectiveness in clinical practice remains uncertain.]

Top posts

Most liked on X and Bluesky
Shaun Ward
@MyNutritionSci · X

I've been fairly impressed by the research of Cognizin/Citicoline in supporting cognitive function (particularly memory). Might give it a try since my short-term memory is hilariously bad. https://t.co/3BS4yVGLKJ https://t.co/MDZnfnO9ub https://t.co/Egp4VD8ewA

May 21, 2024 · 4 likes · 1 share · 2,386 followers View post →
Anssi H. Manninen | Mass Balance Man
@KingManninen · X

Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis https://t.co/F0I79pP2dQ #mdpinutrients via @Nutrients_MDPI

Jan 23, 2023 · 2 likes · 1 share · 1,073 followers View post →
株式会社サンクト
@sanct200301 · X

イタリアのローマバイオ医療大学の研究者らの最新のシステマティックレビュー&メタアナリシスによると、シチコリンの摂取は認知機能にポジティブな効果を与える可能性があるものの、まだエビデンスが不十分としています。#シチコリン #認知機能 https://t.co/fIA94FpaFU

Jan 29, 2023 · 2 likes · 775 followers View post →
Simon Hill MSc, BSc
@theproof · X

RT @WardWriting: I've been fairly impressed by the research of Cognizin/Citicoline in supporting cognitive function (particularly memory).…

May 21, 2024 · 1 share · 34,341 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

RT @KingManninen: Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis https://t.co/F0I…

Jan 25, 2023 · 1 share · 11,326 followers View post →
Nutr Reviews
@NutrReview · X

Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis https://t.co/RsV5kvAD84

Jan 21, 2023 · 226 followers View post →

All mentions

Essential Nutrients for Health After Age 50

In this video, Dr. Luca Leoni discusses the essential vitamins and minerals after 50 years to promote overall well-being. Key nutrients like vitamin D, B6, B9, and B12 can reduce cognitive decline and support hormonal…

Dottor Luca · Jun 6, 2025 1,239 views
Simon Hill MSc, BSc
@theproof · X

RT @WardWriting: I've been fairly impressed by the research of Cognizin/Citicoline in supporting cognitive function (particularly memory).…

May 21, 2024 · 1 share · 34,341 followers View post →
Shaun Ward
@MyNutritionSci · X

I've been fairly impressed by the research of Cognizin/Citicoline in supporting cognitive function (particularly memory). Might give it a try since my short-term memory is hilariously bad. https://t.co/3BS4yVGLKJ https://t.co/MDZnfnO9ub https://t.co/Egp4VD8ewA

May 21, 2024 · 4 likes · 1 share · 2,386 followers View post →
株式会社サンクト
@sanct200301 · X

イタリアのローマバイオ医療大学の研究者らの最新のシステマティックレビュー&メタアナリシスによると、シチコリンの摂取は認知機能にポジティブな効果を与える可能性があるものの、まだエビデンスが不十分としています。#シチコリン #認知機能 https://t.co/fIA94FpaFU

Jan 29, 2023 · 2 likes · 775 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

RT @KingManninen: Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis https://t.co/F0I…

Jan 25, 2023 · 1 share · 11,326 followers View post →
Anssi H. Manninen | Mass Balance Man
@KingManninen · X

Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis https://t.co/F0I79pP2dQ #mdpinutrients via @Nutrients_MDPI

Jan 23, 2023 · 2 likes · 1 share · 1,073 followers View post →
Nutr Reviews
@NutrReview · X

Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis https://t.co/RsV5kvAD84

Jan 21, 2023 · 226 followers View post →
Vizatime Per 17 Dhk | TikTok
TikTok

http://dx.doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/1087054715593633 http://dx.doi.org/10.4236/fns.2012.36103 http://dx.doi.org/10.1093/jn ...

Dec 15, 2025 View →
Erome Viss Tantric | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Dottor Luca Naso | TikTok
TikTok

https://doi.org/10.3390/nu13113757. MAGNESIO: Gholizadeh‐Moghaddam, M., Ghasemi‐Tehrani ... https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Tizio Dei Sogni | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Come Fare Un Sogno Lucido | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Citicolina Inyectable | TikTok
TikTok

Link: https://doi.org/10.3390/nu12103113 - Studio sulle dosi efficaci di citicolina ... https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Luca E Paolo Lucido Si O Lucido No | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Dr Lucas Products Contact Number | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Boukari Di Le Lion | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
B9 17d | TikTok
TikTok

http://dx.doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/1087054715593633 http://dx.doi.org/10.4236/fns.2012.36103 http://dx.doi.org/10.1093/jn ...

Dec 15, 2025 View →
Luca Ries | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Bori E Pariolini Significato | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Luca Il Maestro Arlia | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Trgovin Eka Purecic | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Quando Sogni La Persona Che Ti Piace | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Non Serve Rifugiarsi Nei Sogni | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Cosqun Ovçular Evi | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
Sleoniita_fp | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Dec 15, 2025 View →
20240703163414_h5t3h33yxv | PDF
News

DOI: 10.3390/nu15020386. Forum Allergy Rhinol, 2023, 13(7): 1061‑1482. DOI: [84] 张微微, 李小刚, 王默力, 等. 奥拉西坦治疗卒中后认知功 10.1002/alr.23079. 能 ...

Dec 15, 2025 View →
中国血管性认知障碍诊治指南(2024版) | PDF
News

DOI: 10.3390/nu15020386. Forum Allergy Rhinol, 2023, 13(7): 1061‑1482. DOI: [84] 张微微, 李小刚, 王默力, 等. 奥拉西坦治疗卒中后认知功 10.1002/alr.23079. 能 ...

Dec 15, 2025 View →
Cosa Fare Quando Ti Trovo in Loop Di Sogni Lucidi E Non Riesci A ...
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Dec 8, 2025 View →
Que Es Petit Suisse Significado | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Dec 1, 2025 View →
Dottor Luca 19 | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Dec 1, 2025 View →
Kira Huberman | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Dec 1, 2025 View →
Dottorluca | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 24, 2025 View →
Idris Vicuña Maya Kibbel | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 24, 2025 View →
Integratore Difese Immunitarie Adulti | TikTok
TikTok

**doi: 10.3390/foods10061360. Disclaimer Integratore alimentare ... http://dx.doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177 ...

Nov 24, 2025 View →
Concetto Trippa Librino Spara | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 17, 2025 View →
Suana Sigillo | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 17, 2025 View →
Dr Lukas Cheney | TikTok
TikTok

http://dx.doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/1087054715593633 http://dx.doi.org/10.4236/fns.2012.36103 http://dx.doi.org ...

Nov 17, 2025 View →
Hai mai sentito dire che “l'intestino è il secondo cervello”? In realt ...
TikTok

... 10.3390/antiox9050386 https://doi.org/10.3390/ijms21186695 https ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Nov 16, 2025 View →
A volte non è solo stanchezza. È come se qualcosa, lentamente, ti ...
TikTok

... 10.3390/antiox9050386 https://doi.org/10.3390/ijms21186695 https ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Nov 14, 2025 View →
Come Fare Sogni Comandati | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 10, 2025 View →
Come Fare Sogni Belli | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 3, 2025 View →
Si A Sfaccim Ra Vit Mij | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Oct 27, 2025 View →
Faser Jeg Ved Det Ikke Sang | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Oct 20, 2025 View →
Lo zinco è un minerale fondamentale: sostiene il sistema ...
TikTok

... 10.3390/nu17091482 https://doi.org/10.1089/acm.2021.0135 http://dx ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Oct 14, 2025 View →
Creatina per le donne: potenzia la tua energia | TikTok
TikTok

... 10.3390/nu13020586 https://doi.org/10.3390/nu14050921 https://doi ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Oct 7, 2025 View →
Sogni Lucidi Dire A Tutti Che Non Sono Reali | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Sep 28, 2025 View →
Il Resveratrolo è uno degli integratori più discussi degli ultimi anni ...
TikTok

... 10.3390/nu17091482 https://doi.org/10.1089/acm.2021.0135 http://dx ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Sep 25, 2025 View →
La vitamina D non è "una delle tante", è LA molecola base. Senza di ...
TikTok

... 10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Sep 16, 2025 View →
Sai cosa colpisce tante persone dopo un ictus? Non tanto la parte ...
TikTok

... 10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Sep 9, 2025 View →
Dra Leonie Apablaza Soto | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

May 21, 2025 View →
Maschera Sogni Lucidi Parte 4 | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

May 5, 2025 View →
T'agg Luat Rind A Vita Mij Comm S Fa Che I Vizzij | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 8, 2024 View →
Tagg Levat Ra Vita Mi Comm S Fa Che Vizij | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Oct 25, 2024 View →
Tagg Luvat A Rind A Vita Mj Comm Se Fa Che Vizij | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Oct 24, 2024 View →
Meditare ogni giorno sembra complicato, ma in realtà è molto più ...
TikTok

... 10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi.org/10.1177 ...

Oct 22, 2024 View →
Il Coraggio Abbinato Alla Dignita Oriana Fallaci | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Oct 20, 2024 View →
Mutazione del gene COMT e impatti sul sonno | TikTok
TikTok

... 10.3390/nu13020586 https://doi.org/10.3390/nu14050921 https://doi ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Jul 11, 2024 View →
Notti in bianco? Ti rigiri nel letto guardando il soffitto, contando p ...
TikTok

... 10.3390/antiox9050386 https://doi.org/10.3390/ijms21186695 https ... nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx ...

Nov 22, 2023 View →
Ho Guardato in Tutti I Posti | TikTok
TikTok

https://doi.org/10.3390/nu15020386 http://dx.doi.org/10.1177/0891988716673466 http://dx.doi.org/10.1016/j.sleep.2020.03.012 http://dx.doi ...

Nov 12, 2022 View →