J Biosci Bioeng March 2023 PMID 36681523

Physiological significance of elevated levels of lactate by exercise training in the brain and body.

Sungjun Lee, Yonghyun Choi, Eunseo Jeong, Jongjun Park, Jiwon Kim, Masayoshi Tanaka, Jonghoon Choi

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Mentions

32
Peak: 28 in Nov 2023
across 2 sources since Jan 2023

Extended reach

268,497
potential audience

Total likes

1,541

Video views

29,835

Mentions per month

Jan 2023 – Jan 2024

Where it's discussed

  • X / Twitter30 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions highlight a shift in perception about lactate, emphasizing phrases like 'should no longer exist' and 'may be a solution,' which reflect strong agreement with the article's conclusions. The tone is optimistic yet analytical and focuses on potential health applications, demonstrating both interest and a moderate depth of engagement. The choice of words such as 'improvement,' 'expression of growth factors,' and 'alleviating diseases' underscores a sense of optimism about the article's significance.

AgreementModerate agreement

Most posts agree that the traditional view of lactate as merely a fatigue marker is outdated, supporting the new research perspective.

InterestHigh interest

Posts show high interest in the potential health benefits, especially related to chronic diseases like Alzheimer's and depression.

EngagementModerate engagement

Some discussions delve into physiological mechanisms and implications, such as the roles of growth factors, indicating a moderate level of deep engagement.

ImpactModerate impact

Posts suggest the research could significantly change how we understand exercise and brain health, though the overall tone indicates early recognition rather than widespread immediate impact.

Abstract in brief

  • Lactate, historically viewed as a waste product causing fatigue, is actually closely linked to energy metabolism and plays beneficial roles in the brain and body, including promoting brain function and potentially alleviating chronic diseases.
  • During exercise, lactate production varies with intensity and not just occurs in muscles but also in other organs; it serves as a key marker for fat oxidation in muscles and becomes an important energy source after exercise when muscle respiration slows.
  • New research suggests lactate can improve brain health by increasing growth factors and may help with stress-related conditions like depression; it is also being studied as a preventive agent for brain diseases like Alzheimer’s, shifting the view of lactate from a fatigue marker to a beneficial molecule.]

Top posts

Most liked on X and Bluesky
Andy Galpin, PhD
@DrAndyGalpin · X

The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effect of lactate may be a solution to alleviating some chronic diseases. E.g., brain (Alzheimer's) & mental (depression) health. https://t.co/jV9hd1u7LJ

Nov 2, 2023 · 145 likes · 27 shares · 94,845 followers View post →
Andy Galpin, PhD
@DrAndyGalpin · X

The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effect of lactate may be a solution to alleviating some chronic diseases.: E.g., brain (Alzheimer's) & mental (depression) health. https://t.co/jV9hd1u7LJ

Nov 2, 2023 · 9 likes · 94,845 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

Furthermore, improvement in brain function by lactate, particularly, through the expression of vascular endothelial growth factor and brain-derived neurotrophic factor, is being increasingly studied. https://t.co/rcFTRQmu98

Jan 25, 2023 · 8 likes · 2 shares · 22,166 followers View post →
William A. Wallace, Ph.D.
@drwilliamwallac · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 8,678 followers View post →
Ignacio Hernando Valle
@nachoafysalud · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 5,834 followers View post →
Luis_AT/PE/MP
@LuisIgl51610 · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 2,334 followers View post →

All mentions

Lactate's Role in Enhancing Brain and Muscle Function

Lactate, once seen as a waste product, is now recognized as a vital energy source and beneficial for brain health. This video explores how exercise-induced lactate influences energy metabolism, promotes brain function…

Physionic · Dec 18, 2023 27,254 views
Tom
@tommypiner · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 6, 2023 · 27 shares · 104 followers View post →
Colin Slager
@slagermeister · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 6, 2023 · 27 shares · 448 followers View post →
Michal Sieroslawski
@micsieroslawski · X

According to Sungjun Lee et al., the perception that lactate is equivalent to fatigue should no longer exist https://t.co/9ZsOZKcgzy

Nov 4, 2023 · 11 followers View post →
alvaro alaor
@alaoralavaro · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 4, 2023 · 27 shares · 543 followers View post →
Cristiane Schmitz
@schmitzcris · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 4, 2023 · 27 shares · 81 followers View post →
Workout School
@school_workout · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 4, 2023 · 27 shares · 32 followers View post →
Quincy Talbot
@quincytalbot · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 158 followers View post →
Mind Your Science!
@MindYourSci · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 134 followers View post →
Donald Kanupp
@NutritionSciGuy · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 50 followers View post →
BrendenMHorn
@BrendenMHorn · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 269 followers View post →
drehman ☕️#ReadWriteThinkCriticallyDaily
@pomdr · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 586 followers View post →
Steve Laubenberg
@SLaubenberg · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 154 followers View post →
Ignacio Hernando Valle
@nachoafysalud · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 3, 2023 · 27 shares · 5,834 followers View post →
Javed Alam
@jalam1001 · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 1,008 followers View post →
Aaron Boyum
@aaronjboyum · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 260 followers View post →
Joe A Kim
@Joe_A_Kim · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 751 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 1,367 followers View post →
Jason Crawhorn
@JCrawhorn · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 123 followers View post →
Arun Karthik
@narcissistak · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 819 followers View post →
SSG_Mat_CSCS
@afronetix · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 202 followers View post →
Pat Bernat
@PatBernat · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 515 followers View post →
JAWPUNCHER
@JordonWadeUSA · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 303 followers View post →
Luis_AT/PE/MP
@LuisIgl51610 · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 2,334 followers View post →
William A. Wallace, Ph.D.
@drwilliamwallac · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 8,678 followers View post →
Cindy Kugler
@Exspec85 · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 230 followers View post →
KOP
@33Kopp143 · X

RT @DrAndyGalpin: The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effe…

Nov 2, 2023 · 27 shares · 357 followers View post →
Andy Galpin, PhD
@DrAndyGalpin · X

The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effect of lactate may be a solution to alleviating some chronic diseases. E.g., brain (Alzheimer's) & mental (depression) health. https://t.co/jV9hd1u7LJ

Nov 2, 2023 · 145 likes · 27 shares · 94,845 followers View post →
Andy Galpin, PhD
@DrAndyGalpin · X

The perception that lactate is equivalent to fatigue should no longer exist. Importantly, controlling physiological effect of lactate may be a solution to alleviating some chronic diseases.: E.g., brain (Alzheimer's) & mental (depression) health. https://t.co/jV9hd1u7LJ

Nov 2, 2023 · 9 likes · 94,845 followers View post →
Luis Carlos Escobar
@luiskescobar · X

https://t.co/USLNKitSxk

May 12, 2023 · 48 followers View post →
Jose Antonio PhD
@JoseAntonioPhD · X

Furthermore, improvement in brain function by lactate, particularly, through the expression of vascular endothelial growth factor and brain-derived neurotrophic factor, is being increasingly studied. https://t.co/rcFTRQmu98

Jan 25, 2023 · 8 likes · 2 shares · 22,166 followers View post →