J Biotechnol February 2023 PMID 36708997

Single-cell RNA sequencing reveals homogeneous transcriptome patterns and low variance in a suspension CHO-K1 and an adherent HEK293FT cell line in culture conditions.

Giulia Borsi, Krishna Motheramgari, Heena Dhiman, Martina Baumann, Elly Sinkala, Max Sauerland, Julian Riba, Nicole Borth

Download social card

Mentions

12
Peak: 3 in Jan 2023
across 3 sources since Jan 2023

Extended reach

16,112
potential audience

Total likes

9

Video views

462

Mentions per month

Jan 2023 – Nov 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube3 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions primarily revolve around the revelation of low variance and homogeneous transcriptome patterns in cell lines, with comments like 'This could streamline biomanufacturing' and questions about how this impacts cell stability and production efficiency. The tone varies from technical to cautiously optimistic, highlighting both interest and a recognition of potential industry impact.

AgreementModerate agreement

Most discussions acknowledge the significance of findings about transcriptome homogeneity, with some expressing skepticism or referencing related research.

InterestModerate interest

Participants show curiosity about the implications of low variance in cell lines, indicating moderate interest.

EngagementModerate engagement

Posts include mentions of technical details, methodology, and potential applications, reflecting moderate deep engagement.

ImpactModerate impact

The discussions suggest the research could influence biotechnological practices, though some posts remain somewhat speculative.

Top posts

Most liked on X and Bluesky
草
@n0rr · X

最近出た論文みても、浮遊細胞だとscRNA-seqしても細胞周期で分類しづらい。たぶん細胞周期が遺伝子発現を直接支配してるんじゃなくて、微小環境に影響して間接的に遺伝子発現に見えてるだけなのだと思う。引用されてた2021年の論文でも同じだった。 https://t.co/guv7rJ01C7 https://t.co/gj84UzmOoX

Feb 22, 2023 · 8 likes · 1 share · 10,984 followers View post →
Transcriptomes
@transcriptomes · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a S... https://t.co/KV4YherezS

Jan 29, 2023 · 1,810 followers View post →
CompBiolPapers
@CompBiolPapers · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a Suspension CHO-K1 and an Adherent HEK293FT Cell Line in Culture Conditions https://t.co/Ao8ISOcV6S

Jan 29, 2023 · 1,775 followers View post →
a
@ayanosatoh · X

RT @n0rr: 最近出た論文みても、浮遊細胞だとscRNA-seqしても細胞周期で分類しづらい。たぶん細胞周期が遺伝子発現を直接支配してるんじゃなくて、微小環境に影響して間接的に遺伝子発現に見えてるだけなのだと思う。引用されてた2021年の論文でも同じだった。 https:…

Feb 22, 2023 · 1 share · 624 followers View post →
single cell papers
@sc_papers · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a Suspension CHO-K1 and an Adherent HEK293FT Cell Line in Culture Conditions https://t.co/WpoJvRDp3v

Jan 29, 2023 · 304 followers View post →
CHO Cell Papers
@CHOculturePaper · X

⚡ Single-cell RNA sequencing reveals homogeneous transcriptome patterns and low variance in a suspension CHO-K1 and an adherent HEK293FT cell line in culture… Journal of biotechnology(2023) https://t.co/Qi7ZAWJRJi @grok summary⬇️ #Biotechnology #Science

Oct 16, 2025 · 78 followers View post →

All mentions

CHO Cell Papers
@CHOculturePaper · X

⚡ Single-cell RNA sequencing reveals homogeneous transcriptome patterns and low variance in a suspension CHO-K1 and an adherent HEK293FT cell line in culture… Journal of biotechnology(2023) https://t.co/Qi7ZAWJRJi @grok summary⬇️ #Biotechnology #Science

Oct 16, 2025 · 78 followers View post →
CHO Cell Papers
@CHOculturePaper · X

YouTube で音声付きで論文紹介中!

Sep 9, 2025 · 72 followers View post →
a
@ayanosatoh · X

RT @n0rr: 最近出た論文みても、浮遊細胞だとscRNA-seqしても細胞周期で分類しづらい。たぶん細胞周期が遺伝子発現を直接支配してるんじゃなくて、微小環境に影響して間接的に遺伝子発現に見えてるだけなのだと思う。引用されてた2021年の論文でも同じだった。 https:…

Feb 22, 2023 · 1 share · 624 followers View post →
草
@n0rr · X

最近出た論文みても、浮遊細胞だとscRNA-seqしても細胞周期で分類しづらい。たぶん細胞周期が遺伝子発現を直接支配してるんじゃなくて、微小環境に影響して間接的に遺伝子発現に見えてるだけなのだと思う。引用されてた2021年の論文でも同じだった。 https://t.co/guv7rJ01C7 https://t.co/gj84UzmOoX

Feb 22, 2023 · 8 likes · 1 share · 10,984 followers View post →
single cell papers
@sc_papers · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a Suspension CHO-K1 and an Adherent HEK293FT Cell Line in Culture Conditions https://t.co/WpoJvRDp3v

Jan 29, 2023 · 304 followers View post →
Transcriptomes
@transcriptomes · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a S... https://t.co/KV4YherezS

Jan 29, 2023 · 1,810 followers View post →
CompBiolPapers
@CompBiolPapers · X

Single-cell RNA Sequencing Reveals Homogeneous Transcriptome Patterns and Low Variance in a Suspension CHO-K1 and an Adherent HEK293FT Cell Line in Culture Conditions https://t.co/Ao8ISOcV6S

Jan 29, 2023 · 1,775 followers View post →