Microb Biotechnol June 2023 PMID 36722614

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli.

Sourik Dey, Marc Blanch-Asensio, Sanjana Balaji Kuttae, Shrikrishnan Sankaran

Mentions

41
Peak: 26 in Feb 2023
across 2 sources since Aug 2022

Extended reach

287,147
potential audience

Total likes

114

Video views

5

Mentions per month

Aug 2022 – Aug 2023

Where it's discussed

  • X / Twitter40 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone of the discussions underscores excitement about the innovative genetic modules that enable high-level protein expression without antibiotics, with phrases like 'exciting development' and mentions of 'first paper' highlighting both novelty and progress. This language, coupled with references to potential medical and safety advantages, illustrates a collective perception of high impact and interest in the study's implications for future probiotic engineering.

AgreementModerate agreement

Most discussions show enthusiasm or neutral acknowledgment of the research, with some expressing excitement about the novelty and potential applications, indicating general support rather than skepticism.

InterestNeutral interest
EngagementNeutral engagement
ImpactNeutral impact

Abstract in brief

  • The study introduces two new genetic modules in Lactiplantibacillus plantarum that enable high-level protein production without relying on antibiotics, bacteriocins, or genetic alterations to the bacterial genome.
  • These modules include a promoter from Salmonella typhimurium, which boosts gene expression up to five times compared to older methods, and toxin-antitoxin systems that help retain the genetic material in the bacteria without traditional selection methods.
  • Overall, these advancements will make it easier to engineer lactobacilli for medical and health applications, offering versatile and sustainable ways to modify these beneficial bacteria.]

Top posts

Most liked on X and Bluesky
Shrikrishnan Sankaran
@ShrikrishnanS · X

Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts to expand the programmability of probiotic lactobacilli for medical applications @MicrobialBiote1 @DeySourik @marcblanch94 https://t.co/ebhhEIUick More in

Feb 1, 2023 · 37 likes · 12 shares · 428 followers View post →
SOURIK DEY
@DeySourik · X

The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblanch94 @ShrikrishnanS @LSCLifeMat https://t.co/H8TXwO9pkw

Feb 1, 2023 · 36 likes · 7 shares · 310 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laboratory. @ShrikrishnanS published the work from his first grant recently in MBT. Read the article here and a summary in tweet 2/2

Feb 17, 2023 · 17 likes · 7 shares · 2,509 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expression without using antibiotic markers. A step toward safer and more effective probiotics‼️ #probiotics, #wellness, #health. Read here

Apr 19, 2023 · 12 likes · 8 shares · 2,509 followers View post →
bioRxiv
@biorxivpreprint · X

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/lE9txIffec #bioRxiv

Aug 5, 2022 · 6 likes · 2 shares · 137,378 followers View post →
bioRxiv Synthetic Biology
@bioRxiv_synbio · X

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/x4zNPJPEFE #biorxiv_synbio

Aug 5, 2022 · 6 likes · 2,015 followers View post →

All mentions

Wiley Microbiology
@wileymicrobio · X

Lactobacilli are often found in nature & used in food fermentation.

Apr 20, 2023 · 65,835 followers View post →
Patricia Bernal
@pbernal209 · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 1,175 followers View post →
Marc Blanch Asensio
@marcblanch94 · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 115 followers View post →
Manuel Sánchez
@ManoloSanchezA · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 1,725 followers View post →
Kenneth Timmis
@KennethTimmis · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 1,234 followers View post →
Peter Guhl bones0@chaos.social chabis ch
@chabis_ch · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 458 followers View post →
Applied Microbiology International
@AMIposts · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 29,281 followers View post →
Shrikrishnan Sankaran
@ShrikrishnanS · X

RT @MicrobialBiote1: SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expr…

Apr 19, 2023 · 8 shares · 428 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

SYNTHETIC BIOLOGY. Exciting development in #probiotics research! Dey et al have discovered a way to modulate gene expression without using antibiotic markers. A step toward safer and more effective probiotics‼️ #probiotics, #wellness, #health. Read here

Apr 19, 2023 · 12 likes · 8 shares · 2,509 followers View post →
juan luis ramos
@ramoslabgranada · X

RT @MicrobialBiote1: From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laborato…

Feb 17, 2023 · 7 shares · 403 followers View post →
Marc Blanch Asensio
@marcblanch94 · X

RT @MicrobialBiote1: From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laborato…

Feb 17, 2023 · 7 shares · 115 followers View post →
Varun Tadimarri
@Vrunvrun3 · X

RT @MicrobialBiote1: From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laborato…

Feb 17, 2023 · 7 shares · 96 followers View post →
Patricia Bernal
@pbernal209 · X

RT @MicrobialBiote1: From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laborato…

Feb 17, 2023 · 7 shares · 1,175 followers View post →
Shrikrishnan Sankaran
@ShrikrishnanS · X

RT @MicrobialBiote1: From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laborato…

Feb 17, 2023 · 7 shares · 428 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

From the Initiative "Promoting new and emerging PI at MBT", we introduce you today to Shrikrishnan Sankaran´s laboratory. @ShrikrishnanS published the work from his first grant recently in MBT. Read the article here and a summary in tweet 2/2

Feb 17, 2023 · 17 likes · 7 shares · 2,509 followers View post →
Dr Rob Leigh
@RobLeigh_ · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 3, 2023 · 12 shares · 605 followers View post →
Nefertiti
@ReloadNefertiti · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 3, 2023 · 12 shares · 401 followers View post →
Daehee Lee
@bioexpert · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 3, 2023 · 7 shares · 191 followers View post →
Akos T. Kovacs
@EvolvedBiofilm · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 3, 2023 · 12 shares · 21,075 followers View post →
Rahul K
@theresearch · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 2, 2023 · 12 shares · 164 followers View post →
juan luis ramos
@ramoslabgranada · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 2, 2023 · 12 shares · 403 followers View post →
Carlos Blondel
@cjblondel · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 5,623 followers View post →
Waliyullahi Ajibola
@WalliyulahiA · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 429 followers View post →
Microbial Biotechnology (MBT)
@MicrobialBiote1 · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 2,509 followers View post →
Vivek Mutalik
@vivek_mutalik · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 5,171 followers View post →
SOURIK DEY
@DeySourik · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 310 followers View post →
Varun Tadimarri
@Vrunvrun3 · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 96 followers View post →
SFB 1027
@SFB_1027 · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 71 followers View post →
Varun Tadimarri
@Vrunvrun3 · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 96 followers View post →
LSC Living Therapeutic Materials
@LSCLifeMat · X

RT @ShrikrishnanS: Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts…

Feb 1, 2023 · 12 shares · 250 followers View post →
LSC Living Therapeutic Materials
@LSCLifeMat · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 250 followers View post →
Shrikrishnan Sankaran
@ShrikrishnanS · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 428 followers View post →
Shrikrishnan Sankaran
@ShrikrishnanS · X

Excited to share the first article emerging solely from my research group! We found and characterized new genetic parts to expand the programmability of probiotic lactobacilli for medical applications @MicrobialBiote1 @DeySourik @marcblanch94 https://t.co/ebhhEIUick More in

Feb 1, 2023 · 37 likes · 12 shares · 428 followers View post →
Marc Blanch Asensio
@marcblanch94 · X

RT @DeySourik: The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblan…

Feb 1, 2023 · 7 shares · 115 followers View post →
SOURIK DEY
@DeySourik · X

The first of something is always very special. I am happy to share the first paper of my PhD. More coming soon!!!! @marcblanch94 @ShrikrishnanS @LSCLifeMat https://t.co/H8TXwO9pkw

Feb 1, 2023 · 36 likes · 7 shares · 310 followers View post →
Engineering Papers
@eng_papers · X

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/7BhGteAr4J

Aug 5, 2022 · 45 followers View post →
Hafsa | حفصة
@HafsaHussain_ · X

RT @biorxivpreprint: Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/l…

Aug 5, 2022 · 2 shares · 473 followers View post →
bioRxiv Synthetic Biology
@bioRxiv_synbio · X

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/x4zNPJPEFE #biorxiv_synbio

Aug 5, 2022 · 6 likes · 2,015 followers View post →
Free56
@Free5620 · X

RT @biorxivpreprint: Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/l…

Aug 5, 2022 · 2 shares · 197 followers View post →
bioRxiv
@biorxivpreprint · X

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilli https://t.co/lE9txIffec #bioRxiv

Aug 5, 2022 · 6 likes · 2 shares · 137,378 followers View post →