February 2023 PMID 36726978

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells.

Rekha Jalandra, Govind K Makharia, Minakshi Sharma, Anil Kumar

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Mentions

13
Peak: 9 in Jan 2023
across 2 sources since Jan 2023

Extended reach

86,227
potential audience

Total likes

36

Video views

59

Mentions per month

Jan 2023 – Oct 2025

Where it's discussed

  • X / Twitter11 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect a recognition of the article's importance, using words like 'deleterious' and 'inflammation' to underscore its significance. References to discoveries by specific scientists and tagging of organizations demonstrate thoughtful engagement and an understanding of the potential implications for health science.

AgreementModerate agreement

Most discussions acknowledge the harmful role of TMA on gut health, with many emphasizing the potential link to inflammation and cancer.

InterestModerate interest

The key topic of gut microbiota and its negative effects garners moderate interest, especially from those in health and biological sciences.

EngagementModerate engagement

Posts demonstrate a somewhat deep engagement by sharing references, tagging relevant organizations, and discussing implications.

ImpactHigh impact

The discussions highlight that this research could significantly influence future studies and clinical approaches to gut health and disease prevention.

Abstract in brief

  • TMA, a compound produced by gut bacteria from dietary precursors, exhibits toxic and inflammatory effects on colon cells, causing DNA damage, oxidative stress, and cell death.
  • Experimental treatments with TMA in both cell cultures and mice demonstrated that increased TMA levels lead to cell cycle arrest, tissue damage, inflammation, and shortened intestines, indicating severe gut health implications.
  • The study highlights the potential harmful role of gut microbiota-derived TMA in promoting colon and rectal inflammation, tissue damage, and overall intestinal health deterioration.]

Top posts

Most liked on X and Bluesky
BRIC-NII
@NImmunology · X

Scientist @AnilKumar_NII discovered a role of gut microbiota-derived trimethylamine (TMA) in #colon inflammation and possibly in #colorectalcancer #Cancer @DBTIndia @rajesh_gokhale @DrJitendraSingh Read full text

Jan 19, 2023 · 22 likes · 2 shares · 19,675 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (TMA) is produced by the intestinal microbiota as a by-product of metabolism of dietary precursors. TMA has been… https://t.co/5C6InLOe9V #immunology

Jan 16, 2023 · 5 likes · 4 shares · 33,830 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells https://t.co/LBUTXXf8mG https://t.co/2o5JoegDmM

Jan 19, 2023 · 2 likes · 24,156 followers View post →
Microbiome Articles
@microbe_article · X

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells. - Jalandra R et al. - https://t.co/aOiavoXPzM #microbiome

Feb 2, 2023 · 1 like · 7,156 followers View post →
Andy Blidy
@ablidy · X

RT @FrontImmunol: New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (…

Jan 16, 2023 · 4 shares · 850 followers View post →
Anil Kumar
@AnilKumar_NII · X

RT @NImmunology: Scientist @AnilKumar_NII discovered a role of gut microbiota-derived trimethylamine (TMA) in #colon inflammation and possi…

Jan 19, 2023 · 2 shares · 237 followers View post →

All mentions

Building Your Microbiome for Health and Longevity

Learn how your gut microbiome influences your overall health, immune system, and aging process. This video explains simple methods like a balanced diet, prebiotics, and probiotics to enhance gut health based on recent…

AevoBiome · Oct 3, 2025 26 views
ACHS Research
@AchsResearch · X

New NUTRITION Research Available. Click Here to Access Article(s): https://t.co/XvxZepNnh2

Feb 4, 2023 · 44 followers View post →
Microbiome Articles
@microbe_article · X

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells. - Jalandra R et al. - https://t.co/aOiavoXPzM #microbiome

Feb 2, 2023 · 1 like · 7,156 followers View post →
Prachi Deshpande
@prachi48868635 · X

RT @NImmunology: Scientist @AnilKumar_NII discovered a role of gut microbiota-derived trimethylamine (TMA) in #colon inflammation and possi…

Jan 19, 2023 · 2 shares · 111 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells https://t.co/LBUTXXf8mG https://t.co/2o5JoegDmM

Jan 19, 2023 · 2 likes · 24,156 followers View post →
Anil Kumar
@AnilKumar_NII · X

RT @NImmunology: Scientist @AnilKumar_NII discovered a role of gut microbiota-derived trimethylamine (TMA) in #colon inflammation and possi…

Jan 19, 2023 · 2 shares · 237 followers View post →
BRIC-NII
@NImmunology · X

Scientist @AnilKumar_NII discovered a role of gut microbiota-derived trimethylamine (TMA) in #colon inflammation and possibly in #colorectalcancer #Cancer @DBTIndia @rajesh_gokhale @DrJitendraSingh Read full text

Jan 19, 2023 · 22 likes · 2 shares · 19,675 followers View post →
Plasmodesmen
@BuettnerManuela · X

RT @FrontImmunol: New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (…

Jan 18, 2023 · 4 shares · 14 followers View post →
Rekha Jalandra
@JalandraRekha · X

RT @FrontImmunol: New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (…

Jan 18, 2023 · 4 shares · 19 followers View post →
TMAO Articles
@TMAOArticles · X

RT @FrontImmunol: New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (…

Jan 17, 2023 · 4 shares · 25 followers View post →
Andy Blidy
@ablidy · X

RT @FrontImmunol: New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (…

Jan 16, 2023 · 4 shares · 850 followers View post →
Frontiers - Immunology
@FrontImmunol · X

New Research: Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells: Trimethylamine (TMA) is produced by the intestinal microbiota as a by-product of metabolism of dietary precursors. TMA has been… https://t.co/5C6InLOe9V #immunology

Jan 16, 2023 · 5 likes · 4 shares · 33,830 followers View post →